SMT201600464B - Procedimento per la preparazione di esterolo - Google Patents

Procedimento per la preparazione di esterolo

Info

Publication number
SMT201600464B
SMT201600464B SM201600464T SM201600464T SMT201600464B SM T201600464 B SMT201600464 B SM T201600464B SM 201600464 T SM201600464 T SM 201600464T SM 201600464 T SM201600464 T SM 201600464T SM T201600464 B SMT201600464 B SM T201600464B
Authority
SM
San Marino
Prior art keywords
esterol
procedure
preparation
Prior art date
Application number
SM201600464T
Other languages
English (en)
Inventor
Johannes Jan Platteeuw
Bennink Herman Jan Tijmen Coelingh
Franciscus Wilhelmus Petrus Damen
Vliet Michiel Christian Alexander Van
Original Assignee
Donesta Bioscience B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44582248&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201600464(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Donesta Bioscience B V filed Critical Donesta Bioscience B V
Publication of SMT201600464B publication Critical patent/SMT201600464B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
SM201600464T 2011-07-19 2016-12-21 Procedimento per la preparazione di esterolo SMT201600464B (it)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161509168P 2011-07-19 2011-07-19
EP11174509A EP2383279A1 (en) 2011-07-19 2011-07-19 Process for the preparation of estetrol
PCT/NL2012/050514 WO2013012328A1 (en) 2011-07-19 2012-07-18 Process for the preparation of estetrol
EP12742968.6A EP2734536B1 (en) 2011-07-19 2012-07-18 Process for the preparation of estetrol

Publications (1)

Publication Number Publication Date
SMT201600464B true SMT201600464B (it) 2017-03-08

Family

ID=44582248

Family Applications (2)

Application Number Title Priority Date Filing Date
SM20160464T SMT201600464T1 (it) 2011-07-19 2012-07-18 Procedimento per la preparazione di esterolo
SM201600464T SMT201600464B (it) 2011-07-19 2016-12-21 Procedimento per la preparazione di esterolo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SM20160464T SMT201600464T1 (it) 2011-07-19 2012-07-18 Procedimento per la preparazione di esterolo

Country Status (16)

Country Link
US (2) US20140235882A1 (it)
EP (2) EP2383279A1 (it)
CN (1) CN103781795B (it)
CA (1) CA2842035C (it)
CY (1) CY1118288T1 (it)
DK (1) DK2734536T3 (it)
ES (1) ES2602227T3 (it)
HR (1) HRP20161467T1 (it)
HU (1) HUE029783T2 (it)
LT (1) LT2734536T (it)
PL (1) PL2734536T3 (it)
PT (1) PT2734536T (it)
RS (1) RS55384B1 (it)
SI (1) SI2734536T1 (it)
SM (2) SMT201600464T1 (it)
WO (1) WO2013012328A1 (it)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE029252T2 (en) * 2011-06-01 2017-02-28 Estetra Sprl Process for the preparation of intermediates of estetrol
SG195121A1 (en) 2011-06-01 2013-12-30 Estetra S A Process for the production of estetrol intermediates
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
EP2764008B1 (en) * 2011-10-07 2016-08-17 Estetra S.P.R.L. Process for the production of estetrol
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
EP3046928B1 (en) * 2013-09-18 2017-02-08 Crystal Pharma, S.A.U. Process for the preparation of estetrol
RS61777B1 (sr) 2015-06-18 2021-06-30 Estetra Sprl Oralno-disperzibilna tableta koja sadrži estetrol
MD3310333T2 (ro) 2015-06-18 2020-06-30 Estetra Sprl Unitate de dozare orodispersabilă care conține un component estetrol
HUE054589T2 (hu) 2015-06-18 2021-09-28 Estetra Sprl Szájban diszpergálódó esztetrol tartalmú tabletta
CN116077454A (zh) 2015-06-18 2023-05-09 埃斯特拉有限责任公司 含雌四醇组分的口腔分散剂量单位
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
DK3781171T3 (da) 2018-04-19 2022-05-02 Estetra Srl Sammensætninger og deres anvendelser til lindring af menopause-associerede symptomer
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
HU231240B1 (hu) * 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
BR112022005359A2 (pt) * 2019-09-27 2022-07-19 Ind Chimica Srl Processo de preparação de (15a,16a,17ss)-estra-1,3,5(10)-trieno-3,15,16,17-tetrol(estetrol) e intermediários do referido processo
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
US12550643B2 (en) * 2021-06-22 2026-02-10 Applied Materials, Inc. Oxidants and strained-ring precursors
IT202100019631A1 (it) 2021-07-23 2023-01-23 Newchem S P A Metodo per produrre estetrolo e i suoi intermedi
WO2023021026A1 (en) 2021-08-17 2023-02-23 Aspen Oss B.V. A synthetic pathway to estra-1,3,5(10)-triene-3,15a,16a,17b-tetrol
HUP2400151A1 (hu) 2024-02-28 2025-09-28 Richter Gedeon Nyrt Ösztetrol-monohidrát kristályosítási eljárás

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Also Published As

Publication number Publication date
CY1118288T1 (el) 2017-06-28
ES2602227T3 (es) 2017-02-20
PT2734536T (pt) 2017-01-02
SMT201600464T1 (it) 2017-03-08
WO2013012328A1 (en) 2013-01-24
US10844088B2 (en) 2020-11-24
US20140235882A1 (en) 2014-08-21
HUE029783T2 (en) 2017-04-28
EP2734536A1 (en) 2014-05-28
LT2734536T (lt) 2016-12-27
EP2734536B1 (en) 2016-09-28
CN103781795B (zh) 2016-08-17
US20170369521A1 (en) 2017-12-28
HRP20161467T1 (hr) 2017-01-27
EP2383279A1 (en) 2011-11-02
DK2734536T3 (en) 2016-12-12
CN103781795A (zh) 2014-05-07
PL2734536T3 (pl) 2017-03-31
RS55384B1 (sr) 2017-03-31
CA2842035A1 (en) 2013-01-24
CA2842035C (en) 2020-06-23
SI2734536T1 (sl) 2017-01-31

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