SMT201600464T1 - Procedimento per la preparazione di esterolo - Google Patents

Procedimento per la preparazione di esterolo

Info

Publication number
SMT201600464T1
SMT201600464T1 SM20160464T SMT201600464T SMT201600464T1 SM T201600464 T1 SMT201600464 T1 SM T201600464T1 SM 20160464 T SM20160464 T SM 20160464T SM T201600464 T SMT201600464 T SM T201600464T SM T201600464 T1 SMT201600464 T1 SM T201600464T1
Authority
SM
San Marino
Prior art keywords
esterol
preparing
procedure
preparing esterol
Prior art date
Application number
SM20160464T
Other languages
English (en)
Inventor
Johannes Jan Platteeuw
Bennink Herman Jan Tijmen Coelingh
Franciscus Wilhelmus Petrus Damen
Vliet Michiel Christian Alexander Van
Original Assignee
Donesta Bioscience B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44582248&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201600464(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Donesta Bioscience B V filed Critical Donesta Bioscience B V
Publication of SMT201600464T1 publication Critical patent/SMT201600464T1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
SM20160464T 2011-07-19 2012-07-18 Procedimento per la preparazione di esterolo SMT201600464T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11174509A EP2383279A1 (en) 2011-07-19 2011-07-19 Process for the preparation of estetrol
PCT/NL2012/050514 WO2013012328A1 (en) 2011-07-19 2012-07-18 Process for the preparation of estetrol
EP12742968.6A EP2734536B1 (en) 2011-07-19 2012-07-18 Process for the preparation of estetrol

Publications (1)

Publication Number Publication Date
SMT201600464T1 true SMT201600464T1 (it) 2017-03-08

Family

ID=44582248

Family Applications (2)

Application Number Title Priority Date Filing Date
SM20160464T SMT201600464T1 (it) 2011-07-19 2012-07-18 Procedimento per la preparazione di esterolo
SM201600464T SMT201600464B (it) 2011-07-19 2016-12-21 Procedimento per la preparazione di esterolo

Family Applications After (1)

Application Number Title Priority Date Filing Date
SM201600464T SMT201600464B (it) 2011-07-19 2016-12-21 Procedimento per la preparazione di esterolo

Country Status (16)

Country Link
US (2) US20140235882A1 (it)
EP (2) EP2383279A1 (it)
CN (1) CN103781795B (it)
CA (1) CA2842035C (it)
CY (1) CY1118288T1 (it)
DK (1) DK2734536T3 (it)
ES (1) ES2602227T3 (it)
HR (1) HRP20161467T1 (it)
HU (1) HUE029783T2 (it)
LT (1) LT2734536T (it)
PL (1) PL2734536T3 (it)
PT (1) PT2734536T (it)
RS (1) RS55384B1 (it)
SI (1) SI2734536T1 (it)
SM (2) SMT201600464T1 (it)
WO (1) WO2013012328A1 (it)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013030833B1 (pt) 2011-06-01 2019-09-03 Estetra S A processo para a preparação de um composto de fórmula (i) e processo para a preparação de estetrol
WO2012164096A1 (en) * 2011-06-01 2012-12-06 Estetra S.A. Process for the production of estetrol intermediates
EP2383279A1 (en) 2011-07-19 2011-11-02 Pantarhei Bioscience B.V. Process for the preparation of estetrol
EP2764008B1 (en) * 2011-10-07 2016-08-17 Estetra S.P.R.L. Process for the production of estetrol
WO2013034780A2 (en) 2012-12-20 2013-03-14 Crystal Pharma, S.A.U. Process for the preparation of estetrol and related compounds
EP3046928B1 (en) 2013-09-18 2017-02-08 Crystal Pharma, S.A.U. Process for the preparation of estetrol
WO2016203044A1 (en) 2015-06-18 2016-12-22 Mithra Pharmaceuticals S.A. Orodispersible tablet containing estetrol
NZ737945A (en) 2015-06-18 2023-06-30 Estetra Sprl Orodispersible dosage unit containing an estetrol component
LT3310345T (lt) 2015-06-18 2021-06-25 Estetra Sprl Burnoje disperguojama tabletė, turinti estetrolio
RS57328B1 (sr) 2015-06-18 2018-08-31 Mithra Pharmaceuticals S A Orodisperzibilna dozna jedinica koja sadrži estetrolsku komponentu
CA3178291A1 (en) 2016-08-05 2018-04-12 Estetra Srl Method for the management of dysmenorrhea and menstrual pain
TWI801561B (zh) 2018-04-19 2023-05-11 比利時商依思特拉私人有限責任公司 化合物及其用於緩解絕經相關症狀的用途
CR20200486A (es) 2018-04-19 2021-01-27 Estetra Sprl Compuestos y sus usos para aliviar los síntomas asociados a la menopausa
HU231240B1 (hu) * 2019-09-03 2022-04-28 Richter Gedeon Nyrt. Ipari eljárás nagytisztaságú ösztetrol hatóanyag előállítására
CN114514237B (zh) * 2019-09-27 2024-07-26 工业化学有限公司 用于制备(15α,16α,17β)-雌-1,3,5(10)-三烯-3,15,16,17-四醇(雌四醇)的工艺及所述工艺的中间体
TWI893101B (zh) 2020-04-16 2025-08-11 比利時商埃斯特拉有限責任公司 具有降低之副作用之避孕組成物
US12550643B2 (en) * 2021-06-22 2026-02-10 Applied Materials, Inc. Oxidants and strained-ring precursors
IT202100019631A1 (it) 2021-07-23 2023-01-23 Newchem S P A Metodo per produrre estetrolo e i suoi intermedi
WO2023021026A1 (en) 2021-08-17 2023-02-23 Aspen Oss B.V. A synthetic pathway to estra-1,3,5(10)-triene-3,15a,16a,17b-tetrol
HUP2400151A1 (hu) 2024-02-28 2025-09-28 Richter Gedeon Nyrt Ösztetrol-monohidrát kristályosítási eljárás

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Also Published As

Publication number Publication date
EP2734536B1 (en) 2016-09-28
EP2734536A1 (en) 2014-05-28
EP2383279A1 (en) 2011-11-02
SMT201600464B (it) 2017-03-08
US10844088B2 (en) 2020-11-24
CY1118288T1 (el) 2017-06-28
HUE029783T2 (en) 2017-04-28
WO2013012328A1 (en) 2013-01-24
RS55384B1 (sr) 2017-03-31
CA2842035C (en) 2020-06-23
CA2842035A1 (en) 2013-01-24
CN103781795A (zh) 2014-05-07
ES2602227T3 (es) 2017-02-20
US20170369521A1 (en) 2017-12-28
DK2734536T3 (en) 2016-12-12
PL2734536T3 (pl) 2017-03-31
CN103781795B (zh) 2016-08-17
HRP20161467T1 (hr) 2017-01-27
SI2734536T1 (sl) 2017-01-31
US20140235882A1 (en) 2014-08-21
LT2734536T (lt) 2016-12-27
PT2734536T (pt) 2017-01-02

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