SMT202000565T1 - Composti di benzossaborolo 4-sostituiti e loro usi - Google Patents

Composti di benzossaborolo 4-sostituiti e loro usi

Info

Publication number
SMT202000565T1
SMT202000565T1 SM20200565T SMT202000565T SMT202000565T1 SM T202000565 T1 SMT202000565 T1 SM T202000565T1 SM 20200565 T SM20200565 T SM 20200565T SM T202000565 T SMT202000565 T SM T202000565T SM T202000565 T1 SMT202000565 T1 SM T202000565T1
Authority
SM
San Marino
Prior art keywords
benzoxaborole compounds
substituted benzoxaborole
substituted
compounds
benzoxaborole
Prior art date
Application number
SM20200565T
Other languages
English (en)
Inventor
Carlos Alemparte-Gallardo
M R K Alley (Dickon)
David Barros-Aguirre
Ilaria Giordano
Vincent Hernandez
Xianfeng Li
Jacob J Plattner
Original Assignee
Glaxosmithkline Ip No 2 Ltd
Anacor Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55409879&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT202000565(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Ip No 2 Ltd, Anacor Pharmaceuticals Inc filed Critical Glaxosmithkline Ip No 2 Ltd
Publication of SMT202000565T1 publication Critical patent/SMT202000565T1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/08Antibacterial agents for leprosy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/04Esters of boric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SM20200565T 2015-02-12 2016-02-12 Composti di benzossaborolo 4-sostituiti e loro usi SMT202000565T1 (it)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP15382054 2015-02-12
EP15382055 2015-02-12
EP15382056 2015-02-12
EP16706002.9A EP3256479B1 (en) 2015-02-12 2016-02-12 4 -substituted benzoxaborole compounds and uses thereof
PCT/IB2016/050775 WO2016128948A1 (en) 2015-02-12 2016-02-12 4 -substituted benzoxaborole compounds and uses thereof

Publications (1)

Publication Number Publication Date
SMT202000565T1 true SMT202000565T1 (it) 2020-11-10

Family

ID=55409879

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20200565T SMT202000565T1 (it) 2015-02-12 2016-02-12 Composti di benzossaborolo 4-sostituiti e loro usi

Country Status (36)

Country Link
US (3) US20180037595A1 (it)
EP (2) EP3256479B1 (it)
JP (2) JP2018506540A (it)
KR (2) KR20170117158A (it)
CN (2) CN107548398A (it)
AU (3) AU2016217508A1 (it)
BR (2) BR112017017211B1 (it)
CA (2) CA2976030C (it)
CL (2) CL2017002059A1 (it)
CO (2) CO2017008809A2 (it)
CR (2) CR20170371A (it)
CY (1) CY1123687T1 (it)
DK (1) DK3256479T3 (it)
DO (2) DOP2017000188A (it)
EA (2) EA036516B1 (it)
ES (1) ES2821951T3 (it)
HR (1) HRP20201597T1 (it)
HU (1) HUE051113T2 (it)
IL (2) IL253864B (it)
LT (1) LT3256479T (it)
MA (2) MA41494B1 (it)
MX (2) MX379057B (it)
MY (1) MY194004A (it)
NZ (1) NZ734379A (it)
PE (2) PE20171348A1 (it)
PH (2) PH12017501428A1 (it)
PL (1) PL3256479T3 (it)
PT (1) PT3256479T (it)
RS (1) RS60885B1 (it)
SG (2) SG11201706511TA (it)
SI (1) SI3256479T1 (it)
SM (1) SMT202000565T1 (it)
TW (2) TW201702250A (it)
UA (1) UA120527C2 (it)
WO (2) WO2016128948A1 (it)
ZA (1) ZA201705456B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA032844B1 (ru) * 2013-08-09 2019-07-31 Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед Трициклические соединения бензоксаборола и их применение
JP7123074B2 (ja) 2017-05-08 2022-08-22 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド マイコバクテリア感染の処置において使用するためのサンフェトリネム、その塩、またはそのエステル
US11834466B2 (en) 2017-11-30 2023-12-05 5Metis, Inc. Benzoxaborole compounds and formulations thereof
US11236115B2 (en) 2018-08-18 2022-02-01 5Metis, Inc. Solid forms of substituted benzoxaborole and compositions thereof
CN110441344B (zh) * 2019-06-25 2020-09-29 北京大学 一种基于固体核磁共振技术检测rna结构的方法
AU2023287202A1 (en) * 2022-06-23 2024-06-06 Shanghai Micurx Pharmaceutical Co., Ltd. Methods and uses of boron compounds in the treatment of nontuberculous mycobacterium infections and pharmaceutical compositions for treatment of same
CN119233977B (zh) * 2022-06-23 2026-03-17 上海盟科药业股份有限公司 硼化合物的前药及其在治疗细菌感染中的用途
KR20240150582A (ko) 2023-04-08 2024-10-15 김태서 맥세이프 배터리팩을 포함한 아이폰 케이스

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9411587D0 (en) * 1994-06-09 1994-08-03 Zeneca Ltd Compound, composition and use
AU4967997A (en) 1996-12-02 1998-06-29 Chisso Corporation Optically active nitro alcohol derivatives, optically active amino alcohol derivates, and process for preparing the same
US7446236B2 (en) 2002-12-02 2008-11-04 Solvias Ag Catalytic hydrogenation of carbon-heteroatom double bonds
NZ578297A (en) 2005-02-16 2010-11-26 Anacor Pharmaceuticals Inc Boron-containing small molecules
JP5084717B2 (ja) 2005-03-08 2012-11-28 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ キラル・ビスオキサゾリン触媒
EP1976536A4 (en) 2005-12-30 2011-03-02 Anacor Pharmaceuticals Inc SMALL MOLECULES CONTAINING BORON
TWM325238U (en) * 2006-12-29 2008-01-11 Universal Scient Ind Co Ltd Voltage regulator and voltage regulating system
KR100848491B1 (ko) 2007-01-16 2008-07-28 영진약품공업주식회사 베타아미노기를 갖는 2-싸이아졸리딘 유도체, 이의약학적으로 허용 가능한 염 및 이의 제조 방법
JO3396B1 (ar) 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
MX2011006334A (es) 2008-12-17 2011-09-22 Anacor Pharmaceuticals Inc Polimorfos de (s)-3-amino-metil-7-(3-hidroxi-propoxi)-3h-benzo-[c] [1,2]-oxaborol-1-ol.
US20110124597A1 (en) * 2009-09-25 2011-05-26 Anacor Pharmaceuticals, Inc. Boron containing small molecules
MX352607B (es) * 2010-04-07 2017-11-30 Glaxosmithkline Llc Star Proceso para la preparacion de benzoxaboroles.
WO2012033858A2 (en) 2010-09-07 2012-03-15 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US8530452B2 (en) 2011-12-22 2013-09-10 Micurx Pharmaceuticals, Inc. Tricyclic boron compounds for antimicrobial therapy
CN102739587B (zh) 2012-06-16 2014-05-21 天地融科技股份有限公司 音频数据传输方法
KR101636431B1 (ko) 2013-07-30 2016-07-05 동아에스티 주식회사 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
EA032844B1 (ru) 2013-08-09 2019-07-31 Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед Трициклические соединения бензоксаборола и их применение

Also Published As

Publication number Publication date
CN107548398A (zh) 2018-01-05
TW201702250A (zh) 2017-01-16
MA41495A (fr) 2017-12-19
EP3256479A1 (en) 2017-12-20
EA201791671A1 (ru) 2018-02-28
PE20171348A1 (es) 2017-09-13
JP6771472B2 (ja) 2020-10-21
ZA201705456B (en) 2019-10-30
AU2020256369A1 (en) 2020-11-12
BR112017017213A2 (pt) 2018-04-03
HRP20201597T1 (hr) 2020-12-25
RS60885B1 (sr) 2020-11-30
CO2017008816A2 (es) 2017-11-10
DOP2017000188A (es) 2017-09-15
MX2017010414A (es) 2018-05-11
EA201791667A1 (ru) 2018-02-28
EP3256480A1 (en) 2017-12-20
US10774096B2 (en) 2020-09-15
CN107531730B (zh) 2020-08-07
CA2976308A1 (en) 2016-08-18
IL253864B (en) 2021-07-29
EP3256479B1 (en) 2020-07-29
MX2017010413A (es) 2018-05-11
UA120527C2 (uk) 2019-12-26
DK3256479T3 (da) 2020-11-02
WO2016128949A1 (en) 2016-08-18
NZ734379A (en) 2023-06-30
LT3256479T (lt) 2020-12-28
PH12017501428A1 (en) 2018-01-15
PE20171432A1 (es) 2017-09-26
CL2017002059A1 (es) 2018-03-16
CA2976030A1 (en) 2016-08-18
AU2016217508A1 (en) 2017-09-28
MX379057B (es) 2025-03-10
CO2017008809A2 (es) 2017-11-10
KR20170117156A (ko) 2017-10-20
EA036516B1 (ru) 2020-11-18
PL3256479T3 (pl) 2021-06-14
CR20170372A (es) 2017-10-19
IL253864A0 (en) 2017-09-28
CA2976030C (en) 2023-09-26
CY1123687T1 (el) 2022-03-24
HUE051113T2 (hu) 2021-01-28
ES2821951T3 (es) 2021-04-28
JP2018506540A (ja) 2018-03-08
JP2018506538A (ja) 2018-03-08
SG11201706510YA (en) 2017-09-28
US20180044353A1 (en) 2018-02-15
BR112017017211A2 (pt) 2018-04-03
MY194004A (en) 2022-11-07
US20180037595A1 (en) 2018-02-08
IL253865A0 (en) 2017-10-31
MA41494B1 (fr) 2020-10-28
KR20170117158A (ko) 2017-10-20
SG11201706511TA (en) 2017-09-28
WO2016128948A1 (en) 2016-08-18
CR20170371A (es) 2018-01-22
US11214582B2 (en) 2022-01-04
CL2017002060A1 (es) 2018-03-16
TWI730953B (zh) 2021-06-21
CN107531730A (zh) 2018-01-02
DOP2017000189A (es) 2018-02-15
TW201643173A (zh) 2016-12-16
AU2016217507B2 (en) 2019-03-14
MA41494A (fr) 2017-12-19
PT3256479T (pt) 2020-10-22
SI3256479T1 (sl) 2020-11-30
PH12017501427A1 (en) 2018-01-15
US20210053996A1 (en) 2021-02-25
AU2016217507A1 (en) 2017-09-28
BR112017017211B1 (pt) 2023-04-25

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