SU1301319A3 - Способ получени бычьего,свиного или человеческого проинсулина - Google Patents

Способ получени бычьего,свиного или человеческого проинсулина Download PDF

Info

Publication number
SU1301319A3
SU1301319A3 SU813264049A SU3264049A SU1301319A3 SU 1301319 A3 SU1301319 A3 SU 1301319A3 SU 813264049 A SU813264049 A SU 813264049A SU 3264049 A SU3264049 A SU 3264049A SU 1301319 A3 SU1301319 A3 SU 1301319A3
Authority
SU
USSR - Soviet Union
Prior art keywords
gly
glu
ala
leu
pro
Prior art date
Application number
SU813264049A
Other languages
English (en)
Russian (ru)
Inventor
Хилл Франк Брюс
Original Assignee
Эли Лилли Энд Компани (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26832281&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SU1301319(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Эли Лилли Энд Компани (Фирма) filed Critical Эли Лилли Энд Компани (Фирма)
Application granted granted Critical
Publication of SU1301319A3 publication Critical patent/SU1301319A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SU813264049A 1980-03-27 1981-03-26 Способ получени бычьего,свиного или человеческого проинсулина SU1301319A3 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13438980A 1980-03-27 1980-03-27
US21069680A 1980-11-28 1980-11-28

Publications (1)

Publication Number Publication Date
SU1301319A3 true SU1301319A3 (ru) 1987-03-30

Family

ID=26832281

Family Applications (1)

Application Number Title Priority Date Filing Date
SU813264049A SU1301319A3 (ru) 1980-03-27 1981-03-26 Способ получени бычьего,свиного или человеческого проинсулина

Country Status (23)

Country Link
EP (1) EP0037255B2 (2)
KR (1) KR840000946B1 (2)
AR (1) AR224933A1 (2)
AU (1) AU540644B2 (2)
CA (1) CA1154435A (2)
DD (1) DD157612A5 (2)
DE (1) DE3161475D1 (2)
DK (1) DK149863C (2)
EG (1) EG15310A (2)
ES (1) ES500747A0 (2)
FI (1) FI810917A7 (2)
GB (1) GB2073204B (2)
GR (1) GR73517B (2)
HU (1) HU185249B (2)
IE (1) IE51172B1 (2)
IL (1) IL62486A (2)
NO (1) NO151898C (2)
NZ (1) NZ196609A (2)
PL (1) PL127843B1 (2)
PT (1) PT72732B (2)
RO (1) RO81951B (2)
SU (1) SU1301319A3 (2)
YU (1) YU76881A (2)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983003413A1 (en) * 1982-03-31 1983-10-13 Genetics Inst Creation of dna sequences encoding modified proinsulin precursors
DK58285D0 (da) * 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
DE3501641A1 (de) * 1985-01-19 1986-07-24 Hoechst Ag, 6230 Frankfurt Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
DE3901719A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur herstellung eines insulinvorlaeufers
DE3901718A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Verfahren zur renaturierung falscher rekombinanten von insulinvorlaeufern
SG46612A1 (en) 1992-12-02 1998-02-20 Hoechst Ag Process for obtaining proinsulin in processing correctly linked cystine bridges
DE4405179A1 (de) * 1994-02-18 1995-08-24 Hoechst Ag Verfahren zur Gewinnung von Insulin mit korrekt verbundenen Cystinbrücken
EP3344651B1 (en) 2015-09-02 2022-03-02 Merck Sharp & Dohme Corp. A process for obtaining insulin with correctly formed disulfide bonds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2253327A1 (de) * 1972-10-31 1974-05-09 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент US № 3883496, кл. С 07 С 103/52, опублик. 1975. Патент US № 3883500, кл. С 07 С. 103/52, опублик. 1975. *

Also Published As

Publication number Publication date
AR224933A1 (es) 1982-01-29
NO811039L (no) 1981-09-28
DK149863C (da) 1987-06-01
RO81951B (ro) 1984-02-28
EG15310A (en) 1985-12-31
HU185249B (en) 1984-12-28
PT72732A (en) 1981-04-01
GB2073204A (en) 1981-10-14
EP0037255B2 (en) 1989-04-05
KR830005251A (ko) 1983-08-03
ES8201957A1 (es) 1982-01-16
DK136481A (da) 1981-09-28
GB2073204B (en) 1983-09-21
KR840000946B1 (ko) 1984-07-01
NZ196609A (en) 1984-02-03
IE810679L (en) 1981-09-27
GR73517B (2) 1984-03-08
FI810917L (fi) 1981-09-28
NO151898B (no) 1985-03-18
PL127843B1 (en) 1983-11-30
IL62486A0 (en) 1981-05-20
DE3161475D1 (en) 1983-12-29
EP0037255A1 (en) 1981-10-07
AU6871981A (en) 1981-10-01
PT72732B (en) 1982-03-23
PL230292A1 (2) 1981-11-27
CA1154435A (en) 1983-09-27
IL62486A (en) 1984-12-31
ES500747A0 (es) 1982-01-16
YU76881A (en) 1984-04-30
FI810917A7 (fi) 1981-09-28
EP0037255B1 (en) 1983-11-23
NO151898C (no) 1985-06-26
DK149863B (da) 1986-10-13
RO81951A (ro) 1984-02-21
DD157612A5 (de) 1982-11-24
IE51172B1 (en) 1986-10-29
AU540644B2 (en) 1984-11-29

Similar Documents

Publication Publication Date Title
Gutte et al. The synthesis of ribonuclease A
Kaiser et al. The amino acid sequence of a myotoxic phospholipase from the venom of Bothrops asper
US4430266A (en) Process for producing an insulin precursor
Sidler et al. The primary structure of Bacillus cereus neutral proteinase and comparison with thermolysin and Bacillus subtilis neutral proteinase
Reimer et al. Small-scale solid-phase O-glycopeptide synthesis of linear and cyclized hexapeptides from blood-clotting factor IX containing O-(α-D-Xyl-1→ 3-α-D-Xyl-1→ 3-β-D-Glc)-L-ser
Nishida et al. Amino acid sequence of a sea anemone toxin from Parasicyonis actinostoloides
Shechter et al. Selective reduction of cystine I-VIII in α-lactalbumin of bovine milk
SHOME et al. Purification and characterization of monkey placental lactogen
Esnard et al. Purification and physicochemical characterization of a new rat plasma proteinase inhibitor, α1-inhibitor III
Yamasaki et al. Amino acid sequence of a biologically active fragment of bovine growth hormone
Chen et al. Amino acid sequence of the λ light chain of a human myeloma immunoglobulin (IgG new)
KR840000946B1 (ko) 인슐린 전구체의 제조방법
Kitagawa et al. Interaction between the A2 and A19 amino acid residues is of critical importance for high biological activity in insulin:[19-leucine-A] insulin
Querinjean et al. Transplantable Immunoglobulin‐Secreting Tumours in Rats: Purification and Chemical Characterization of Four Kappa Chains from LOU/Wsl Rats
Offer The N-terminus of myosin I. Studies on N-acetyl peptides from a pronase digest of myosin
Harris et al. The carboxymethylation of human metmyoglobin
Smith et al. The use of high-performance liquid chromatography in the isolation and characterisation of mouse and rat epidermal growth factors and examination of apparent heterogeneity
RU2122549C1 (ru) Способ хроматографического выделения и очистки белков, пептидов и их комплексов
Tempst et al. Separation of peptides by reverse-phase high-performance liquid chromatography using propyl-and cyanopropylsilyl supports
Smith et al. Studies on ovalbumin. IV. Trypsin digsestion and the cystine peptides of ovalbumin and S-ovalbumin
GOTO et al. Conformation of the constant fragment of the immunoglobulin light chain: effect of cleavage of the polypeptide chain and the disulfide bond
Olsen et al. Further characterization of human eosinophil peroxidase
RU2045535C1 (ru) Способ получения проинсулина человека
Piot et al. Identification of peptides, from a peptic haemoglobin hydrolysate produced at pilot-plant scale, by high-performance liquid chromatography and mass spectrometry
Cannella et al. Multiple forms of bovine liver rhodanese