SU1433413A3 - Способ получени замещенного имидазо @ 1,5- @ пиридина или его фармацевтически приемлемой соли - Google Patents

Способ получени замещенного имидазо @ 1,5- @ пиридина или его фармацевтически приемлемой соли Download PDF

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Publication number
SU1433413A3
SU1433413A3 SU853917403A SU3917403A SU1433413A3 SU 1433413 A3 SU1433413 A3 SU 1433413A3 SU 853917403 A SU853917403 A SU 853917403A SU 3917403 A SU3917403 A SU 3917403A SU 1433413 A3 SU1433413 A3 SU 1433413A3
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USSR - Soviet Union
Prior art keywords
pyridine
compound
imidazo
solution
acceptable salt
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SU853917403A
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English (en)
Russian (ru)
Inventor
Джонстон Браун Лесли
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Циба-Гейги Аг (Фирма)
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
SU853917403A 1984-06-20 1985-06-19 Способ получени замещенного имидазо @ 1,5- @ пиридина или его фармацевтически приемлемой соли SU1433413A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/622,421 US4617307A (en) 1984-06-20 1984-06-20 Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors

Publications (1)

Publication Number Publication Date
SU1433413A3 true SU1433413A3 (ru) 1988-10-23

Family

ID=24494112

Family Applications (6)

Application Number Title Priority Date Filing Date
SU853917403A SU1433413A3 (ru) 1984-06-20 1985-06-19 Способ получени замещенного имидазо @ 1,5- @ пиридина или его фармацевтически приемлемой соли
SU864027755A SU1436879A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений,или их стереоизомеров,или смеси стереоизомеров,или их кислотно-аддитивных солей
SU864027756A SU1482530A3 (ru) 1984-06-20 1986-07-02 Способ получени производных имидазола, их стереоизомеров, смеси стереоизомеров или их фармацевтически приемлемых солей
SU864027754A SU1436878A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений,или их кислотно-аддитивных солей,или их стереоизомеров,или смеси стереоизомеров
SU864027758A SU1443802A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений, или их стереоизомеров, или смеси стереоизомеров, или их кислотно-аддитивных солей
SU864027757A SU1436880A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений,или их стереоизомеров,или смеси стереоизомеров,или их кислотно-аддитивных солей

Family Applications After (5)

Application Number Title Priority Date Filing Date
SU864027755A SU1436879A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений,или их стереоизомеров,или смеси стереоизомеров,или их кислотно-аддитивных солей
SU864027756A SU1482530A3 (ru) 1984-06-20 1986-07-02 Способ получени производных имидазола, их стереоизомеров, смеси стереоизомеров или их фармацевтически приемлемых солей
SU864027754A SU1436878A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений,или их кислотно-аддитивных солей,или их стереоизомеров,или смеси стереоизомеров
SU864027758A SU1443802A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений, или их стереоизомеров, или смеси стереоизомеров, или их кислотно-аддитивных солей
SU864027757A SU1436880A3 (ru) 1984-06-20 1986-07-02 Способ получени замещенных азотсодержащих бициклических соединений,или их стереоизомеров,или смеси стереоизомеров,или их кислотно-аддитивных солей

Country Status (31)

Country Link
US (1) US4617307A (2)
EP (1) EP0165904B1 (2)
JP (1) JPS6112688A (2)
KR (1) KR900008566B1 (2)
AT (1) ATE62415T1 (2)
AU (1) AU589565B2 (2)
BG (7) BG60262B2 (2)
CA (1) CA1276633C (2)
CS (1) CS268672B2 (2)
CY (1) CY1750A (2)
DD (1) DD237510A5 (2)
DE (1) DE3582452D1 (2)
DK (1) DK170302B1 (2)
DZ (1) DZ799A1 (2)
ES (6) ES8702406A1 (2)
FI (1) FI80694C (2)
GR (1) GR851487B (2)
HK (1) HK23494A (2)
HU (1) HU202529B (2)
IE (1) IE58070B1 (2)
IL (1) IL75546A (2)
MA (1) MA20459A1 (2)
MX (1) MX9203369A (2)
NO (1) NO162467C (2)
NZ (1) NZ212483A (2)
PH (1) PH23390A (2)
PL (6) PL145104B1 (2)
PT (1) PT80661B (2)
RO (1) RO92583A (2)
SU (6) SU1433413A3 (2)
ZA (1) ZA854615B (2)

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* Cited by examiner, † Cited by third party
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