SU657748A3 - Способ получени 2-/4-(теноил-3)фенил/-пропионовой кислоты - Google Patents

Способ получени 2-/4-(теноил-3)фенил/-пропионовой кислоты

Info

Publication number: SU657748A3
Authority: SU; USSR - Soviet Union
Prior art keywords: mol; phenyl; formula; tenoyl; thenoyl
Prior art date: 1976-03-24

Application number

SU772462808A

Other languages

English (en)

Russian (ru)

Inventor

Брие Филипп

Бертелон Жан-Жак

Депен Жан-Клод

Бетбедер-Матибе Анни

Original Assignee

Лифа Лионнэз Эндюстриель Фармасетик, (Фирма)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-03-24

Filing date

1977-03-23

Publication date

1979-04-15

1977-03-23 Application filed by Лифа Лионнэз Эндюстриель Фармасетик, (Фирма) filed Critical Лифа Лионнэз Эндюстриель Фармасетик, (Фирма)

1979-04-15 Application granted granted Critical

1979-04-15 Publication of SU657748A3 publication Critical patent/SU657748A3/ru

Links

XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Substances CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title 1
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 6
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 4
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 3
238000001704 evaporation Methods 0.000 claims 3
230000008020 evaporation Effects 0.000 claims 3
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 3
238000002360 preparation method Methods 0.000 claims 3
239000000243 solution Substances 0.000 claims 3
239000002904 solvent Substances 0.000 claims 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 claims 2
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 claims 2
238000006243 chemical reaction Methods 0.000 claims 2
238000001816 cooling Methods 0.000 claims 2
GNOIPBMMFNIUFM-UHFFFAOYSA-N hexamethylphosphoric triamide Chemical compound CN(C)P(=O)(N(C)C)N(C)C GNOIPBMMFNIUFM-UHFFFAOYSA-N 0.000 claims 2
238000010992 reflux Methods 0.000 claims 2
239000012312 sodium hydride Substances 0.000 claims 2
229910000104 sodium hydride Inorganic materials 0.000 claims 2
VQDJODAWOFNASI-UHFFFAOYSA-N 2-propylpropanedioic acid Chemical compound CCCC(C(O)=O)C(O)=O VQDJODAWOFNASI-UHFFFAOYSA-N 0.000 claims 1
OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 claims 1
238000005904 alkaline hydrolysis reaction Methods 0.000 claims 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
229910052782 aluminium Inorganic materials 0.000 claims 1
239000008346 aqueous phase Substances 0.000 claims 1
239000007864 aqueous solution Substances 0.000 claims 1
239000002585 base Substances 0.000 claims 1
238000009835 boiling Methods 0.000 claims 1
238000004821 distillation Methods 0.000 claims 1
238000001035 drying Methods 0.000 claims 1
238000002474 experimental method Methods 0.000 claims 1
239000012467 final product Substances 0.000 claims 1
238000011010 flushing procedure Methods 0.000 claims 1
239000005457 ice water Substances 0.000 claims 1
238000004519 manufacturing process Methods 0.000 claims 1
239000000203 mixture Substances 0.000 claims 1
PYLWMHQQBFSUBP-UHFFFAOYSA-N monofluorobenzene Chemical compound FC1=CC=CC=C1 PYLWMHQQBFSUBP-UHFFFAOYSA-N 0.000 claims 1
229910052757 nitrogen Inorganic materials 0.000 claims 1
239000012074 organic phase Substances 0.000 claims 1
239000002798 polar solvent Substances 0.000 claims 1
239000000047 product Substances 0.000 claims 1
239000011541 reaction mixture Substances 0.000 claims 1
235000017557 sodium bicarbonate Nutrition 0.000 claims 1
229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
235000011121 sodium hydroxide Nutrition 0.000 claims 1
239000007787 solid Substances 0.000 claims 1
238000003756 stirring Methods 0.000 claims 1
239000000725 suspension Substances 0.000 claims 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Rheumatology (AREA)
Pharmacology & Pharmacy (AREA)
Pain & Pain Management (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)

SU772462808A 1976-03-24 1977-03-23 Способ получени 2-/4-(теноил-3)фенил/-пропионовой кислоты SU657748A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7608470A FR2345148A1 (fr)	1976-03-24	1976-03-24	Nouvel acide propionique substitue, preparation et application

Publications (1)

Publication Number	Publication Date
SU657748A3 true SU657748A3 (ru)	1979-04-15

Family

ID=9170850

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SU772462808A SU657748A3 (ru)	1976-03-24	1977-03-23	Способ получени 2-/4-(теноил-3)фенил/-пропионовой кислоты

Country Status (26)

Country	Link
JP (1)	JPS52139057A (cs)
AR (1)	AR212262A1 (cs)
AT (1)	AT358026B (cs)
AU (1)	AU2351877A (cs)
BE (1)	BE852463A (cs)
CA (1)	CA1102343A (cs)
CH (1)	CH597220A5 (cs)
CS (1)	CS199667B2 (cs)
DD (1)	DD128778A5 (cs)
DE (1)	DE2711585A1 (cs)
DK (1)	DK128077A (cs)
ES (1)	ES457112A1 (cs)
FR (1)	FR2345148A1 (cs)
GB (1)	GB1517688A (cs)
HU (1)	HU176990B (cs)
IE (1)	IE44660B1 (cs)
IL (1)	IL51720A0 (cs)
IT (1)	IT1115272B (cs)
MX (1)	MX4565E (cs)
NL (1)	NL7703215A (cs)
NO (1)	NO771033L (cs)
OA (1)	OA06109A (cs)
SE (1)	SE7703317L (cs)
SU (1)	SU657748A3 (cs)
YU (1)	YU65377A (cs)
ZA (1)	ZA771724B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2030131B (en) *	1978-09-12	1982-12-22	Taiyo Pharma Ind	Process for producing 2-(4-(2-thienyl-carbonyl) phenyl) propionic acid
EP0046337A3 (en) *	1980-08-20	1982-09-15	Imperial Chemical Industries Plc	Triazole compounds, a process for preparing them, their use as plant and pharmaceutical fungicides and as plant growth regulators and compositions containing them
GB2181728B (en) *	1985-10-21	1990-01-24	Indian Drugs & Pharma	4-(3-thienyl)phenylalkanoic acids and derivatives and process for their preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1007643A (en) *	1972-10-24	1977-03-29	Janssen Pharmaceutica Naamloze Vennootschap	Aroyl-substituted phenylacetic acid derivatives

1976
- 1976-03-24 FR FR7608470A patent/FR2345148A1/fr active Granted
1977
- 1977-03-11 YU YU00653/77A patent/YU65377A/xx unknown
- 1977-03-15 BE BE175792A patent/BE852463A/xx not_active IP Right Cessation
- 1977-03-15 AT AT176577A patent/AT358026B/de not_active IP Right Cessation
- 1977-03-17 DE DE19772711585 patent/DE2711585A1/de not_active Withdrawn
- 1977-03-18 CS CS771807A patent/CS199667B2/cs unknown
- 1977-03-21 IT IT7721461A patent/IT1115272B/it active
- 1977-03-21 CA CA274,355A patent/CA1102343A/en not_active Expired
- 1977-03-22 ZA ZA00771724A patent/ZA771724B/xx unknown
- 1977-03-22 CH CH359977A patent/CH597220A5/xx not_active IP Right Cessation
- 1977-03-22 IL IL51720A patent/IL51720A0/xx unknown
- 1977-03-23 IE IE616/77A patent/IE44660B1/en unknown
- 1977-03-23 MX MX775559U patent/MX4565E/es unknown
- 1977-03-23 GB GB12327/77A patent/GB1517688A/en not_active Expired
- 1977-03-23 DK DK128077A patent/DK128077A/da not_active Application Discontinuation
- 1977-03-23 NO NO771033A patent/NO771033L/no unknown
- 1977-03-23 ES ES457112A patent/ES457112A1/es not_active Expired
- 1977-03-23 SE SE7703317A patent/SE7703317L/xx unknown
- 1977-03-23 HU HU77LI310A patent/HU176990B/hu unknown
- 1977-03-23 SU SU772462808A patent/SU657748A3/ru active
- 1977-03-23 AU AU23518/77A patent/AU2351877A/en not_active Expired
- 1977-03-24 DD DD7700198055A patent/DD128778A5/xx unknown
- 1977-03-24 NL NL7703215A patent/NL7703215A/xx not_active Application Discontinuation
- 1977-03-24 JP JP3164377A patent/JPS52139057A/ja active Pending
- 1977-03-24 AR AR266969A patent/AR212262A1/es active
- 1977-03-28 OA OA56120A patent/OA06109A/xx unknown

Also Published As

Publication number	Publication date
NO771033L (no)	1977-09-27
IT1115272B (it)	1986-02-03
SE7703317L (sv)	1977-09-25
IL51720A0 (en)	1977-05-31
FR2345148B1 (cs)	1978-10-20
IE44660L (en)	1977-09-24
DE2711585A1 (de)	1977-09-29
HU176990B (hu)	1981-06-28
BE852463A (fr)	1977-09-15
CA1102343A (en)	1981-06-02
ZA771724B (en)	1978-02-22
DD128778A5 (de)	1977-12-07
ATA176577A (de)	1980-01-15
MX4565E (es)	1982-06-17
AR212262A1 (es)	1978-06-15
CS199667B2 (en)	1980-07-31
JPS52139057A (en)	1977-11-19
CH597220A5 (cs)	1978-03-31
GB1517688A (en)	1978-07-12
AU2351877A (en)	1978-09-28
FR2345148A1 (fr)	1977-10-21
ES457112A1 (es)	1978-03-01
AT358026B (de)	1980-08-11
NL7703215A (nl)	1977-09-27
DK128077A (da)	1977-09-25
OA06109A (fr)	1981-06-30
YU65377A (en)	1983-01-21
IE44660B1 (en)	1982-02-10

Publication	Publication Date	Title
US4120874A (en)	1978-10-17	Diesters of 6-cyano-2,2-tetrahydropyrandicarboxylates
SU657748A3 (ru)	1979-04-15	Способ получени 2-/4-(теноил-3)фенил/-пропионовой кислоты
JPH0529344B2 (cs)	1993-04-30
FR2803846A1 (fr)	2001-07-20	3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation
SU516341A3 (ru)	1976-05-30	Способ получени замещенных бензофенонов
US20050261513A1 (en)	2005-11-24	Process for producing indenol esters or ethers
US5264630A (en)	1993-11-23	Halo-substituted thiobutanals
SU791718A1 (ru)	1980-12-30	Бицикло-/1,1,0/-бутанди-/спироциклобутан/ и способ его получени
JPS6240355B2 (cs)	1987-08-27
JPH0511110B2 (cs)	1993-02-12
SU303866A1 (ru)	1977-07-25	Способ получени -дифенилацетонов
SU963462A3 (ru)	1982-09-30	Способ получени 2-арилпропионовой кислоты
SU383373A1 (ru)	1975-05-05	Способ получени динатриевой соли дисульфида 3,3-дипропандисульфокислоты
SU493964A3 (ru)	1975-11-28	Способ производных изоиндолина или их солей
JPH0237914B2 (cs)	1990-08-28
SU648100A3 (ru)	1979-02-15	Способ получени замещенных или незамещенных производных 3-тиофурана
JPH0210829B2 (cs)	1990-03-09
US3979415A (en)	1976-09-07	Method of preparation of sulfonated, dialkyl-substituted benzodioxoles
JPS6120529B2 (cs)	1986-05-22
RU2017709C1 (ru)	1994-08-15	Способ получения дельта-пиронена
JPS6024085B2 (ja)	1985-06-11	メタアクロレンアセタ−ルを原料とするジヒドロタゲトンの製造法
RU1473300C (ru)	1995-02-09	Способ получения 4-бензоиламино-3-оксотетрагидротиофена
SU996417A1 (ru)	1983-02-15	8,8-Диалкил-9-тиа-1,4-диазаспиро /5,5/ ундеканы
SU395354A1 (ru)	1973-08-28	Способ получения полных или неполных ариловых эфиров фенолов или нафтолов
SU1616901A1 (ru)	1990-12-30	Способ получени симметричных органилселенидов