TN2009000199A1 - Heteromonocyclic compound and use thereof - Google Patents

Heteromonocyclic compound and use thereof

Info

Publication number: TN2009000199A1
Authority: TN; Tunisia
Prior art keywords: formula; compound; group represented; diseases; heteromonocyclic compound
Prior art date: 2006-11-24

Application number

TNP2009000199A

Other languages

English (en)

Inventor

Takanobu Kuroita

Hiroki Sakamoto

Hideyuki Igawa

Minoru Sasaki

Kouhei Asano

Tsuyoshi Maekawa

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-11-24

Filing date

2009-05-20

Publication date

2010-10-18

2009-05-20 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2010-10-18 Publication of TN2009000199A1 publication Critical patent/TN2009000199A1/fr

Links

-1 Heteromonocyclic compound Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
208000015114 central nervous system disease Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
208000030159 metabolic disease Diseases 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

TNP2009000199A 2006-11-24 2009-05-20 Heteromonocyclic compound and use thereof TN2009000199A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2006317839		2006-11-24
JP2007232106		2007-09-06
PCT/JP2007/073004 WO2008062905A2 (fr)	2006-11-24	2007-11-21	Composé hétéromonocyclique et ses utilisations

Publications (1)

Publication Number	Publication Date
TN2009000199A1 true TN2009000199A1 (en)	2010-10-18

Family

ID=39205144

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2009000199A TN2009000199A1 (en)	2006-11-24	2009-05-20	Heteromonocyclic compound and use thereof

Country Status (21)

Country	Link
US (2)	US20100056526A1 (fr)
EP (2)	EP2256115A1 (fr)
JP (1)	JP2010510962A (fr)
KR (1)	KR20090085117A (fr)
AR (1)	AR063912A1 (fr)
AU (1)	AU2007322608A1 (fr)
BR (1)	BRPI0719060A2 (fr)
CA (1)	CA2670404A1 (fr)
CL (1)	CL2007003352A1 (fr)
CO (1)	CO6231035A2 (fr)
CR (1)	CR10847A (fr)
EA (1)	EA200970510A1 (fr)
EC (1)	ECSP099461A (fr)
IL (1)	IL198819A0 (fr)
MA (1)	MA30985B1 (fr)
MX (1)	MX2009005449A (fr)
NO (1)	NO20092415L (fr)
PE (1)	PE20081228A1 (fr)
TN (1)	TN2009000199A1 (fr)
TW (1)	TW200829581A (fr)
WO (1)	WO2008062905A2 (fr)

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US8086575B2 (en)	2004-09-23	2011-12-27	Rovi Solutions Corporation	Methods and apparatus for integrating disparate media formats in a networked media system
US8607287B2 (en)	2005-12-29	2013-12-10	United Video Properties, Inc.	Interactive media guidance system having multiple devices
US9681105B2 (en)	2005-12-29	2017-06-13	Rovi Guides, Inc.	Interactive media guidance system having multiple devices
EP2256115A1 (fr) *	2006-11-24	2010-12-01	Takeda Pharmaceutical Company Limited	Composé hétéromonocyclique et ses utilisations
US7803940B2 (en) *	2006-11-24	2010-09-28	Takeda Pharmaceutical Company Limited	Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
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EP2420501A4 (fr) *	2009-04-17	2012-08-29	Kowa Co	Nouveau composé ayant une structure 3-hétéroarylpyrimidin-4-(3h)-one et préparation pharmaceutique contenant celui-ci
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US20120322819A1 (en) *	2010-02-25	2012-12-20	Kowa Company, Ltd.	Compound containing a novel 4-alkoxypyrimidine structure and medicine containing same
CA2835596A1 (fr) *	2010-05-11	2011-11-17	8337187 Canada Inc.	Derive benzo- ou pyrido-imidazole
JPWO2012011592A1 (ja) *	2010-07-23	2013-09-09	武田薬品工業株式会社	複素環化合物およびその用途
CA2813911A1 (fr)	2010-10-07	2012-04-12	Takeda Pharmaceutical Company Limited	Derives de 1,4-oxazepane
WO2012078674A1 (fr)	2010-12-06	2012-06-14	Confluence Life Sciences, Inc.	Composés indole/indazole-pyrimidinyle substitués
US8563558B2 (en)	2010-12-06	2013-10-22	Confluence Life Sciences, Inc.	Substituted pyridine urea compounds
CA2819889C (fr)	2010-12-06	2020-12-15	Confluence Life Sciences, Inc.	Composes pyridinone-pyridinyle substitues
US9359300B2 (en)	2010-12-06	2016-06-07	Confluence Life Sciences, Inc.	Methyl/difluorophenyl-methoxy substituted pyridinone-pyridinyl compounds, methyl-pyridinyl-methoxy substituted pyridinone-pyridinyl compounds, and methyl-pyrimidinyl-methoxy substituted pyridinone-pyridinyl compounds
PL2687523T3 (pl)	2011-03-14	2016-06-30	Kowa Co	Nowa pochodna fenylopirydyny i lek zawierający ją
EP2567959B1 (fr)	2011-09-12	2014-04-16	Sanofi	Dérivés d'amide d'acide 6-(4-hydroxy-phényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
US9056110B2 (en)	2011-12-06	2015-06-16	Confluence Life Sciences, Inc.	Substituted pyrimidinone-phenyl-pyrimidinyl compounds
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JO3470B1 (ar)	2012-10-08	2020-07-05	Merck Sharp & Dohme	مشتقات 5- فينوكسي-3h-بيريميدين-4-أون واستخدامها كمثبطات ناسخ عكسي ل hiv
CA2917344C (fr)	2013-06-07	2021-09-07	Confluence Life Sciences, Inc.	Composes de pyridinone-pyridinyle substitues avec methyle/fluoro-pyridinyle-methoxy et des composes de pyridinone-pyridinyle substitues avec fluoro-pyrimidinyl-methoxy
BR112015031291A2 (pt)	2013-06-20	2017-07-25	Bayer Cropscience Ag	derivados de sulfureto de arila e derivados de arilalquil sulfóxido como acaricidas e inseticidas
EP3010889B1 (fr)	2013-06-20	2018-10-03	Bayer CropScience Aktiengesellschaft	Dérivés d'arylsulfure et d'arylsulfoxyde comme acaricides et insecticides
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US7803940B2 (en) *	2006-11-24	2010-09-28	Takeda Pharmaceutical Company Limited	Heteromonocyclic compound or a salt thereof having strong antihypertensive action, insulin sensitizing activity and the like production thereof and use thereof for prophylaxis or treatment of cardiovascular diseases, metabolic diseases and/or central nervous system diseases
EP2256115A1 (fr) *	2006-11-24	2010-12-01	Takeda Pharmaceutical Company Limited	Composé hétéromonocyclique et ses utilisations

2007
- 2007-11-21 EP EP10173592A patent/EP2256115A1/fr not_active Withdrawn
- 2007-11-21 MX MX2009005449A patent/MX2009005449A/es not_active Application Discontinuation
- 2007-11-21 AU AU2007322608A patent/AU2007322608A1/en not_active Abandoned
- 2007-11-21 KR KR1020097012959A patent/KR20090085117A/ko not_active Withdrawn
- 2007-11-21 JP JP2009521472A patent/JP2010510962A/ja not_active Abandoned
- 2007-11-21 BR BRPI0719060-3A2A patent/BRPI0719060A2/pt not_active IP Right Cessation
- 2007-11-21 EP EP07832719A patent/EP2074117A2/fr not_active Withdrawn
- 2007-11-21 US US12/516,099 patent/US20100056526A1/en not_active Abandoned
- 2007-11-21 EA EA200970510A patent/EA200970510A1/ru unknown
- 2007-11-21 US US11/943,910 patent/US20080207654A1/en not_active Abandoned
- 2007-11-21 WO PCT/JP2007/073004 patent/WO2008062905A2/fr not_active Ceased
- 2007-11-21 CA CA002670404A patent/CA2670404A1/fr not_active Abandoned
- 2007-11-23 PE PE2007001629A patent/PE20081228A1/es not_active Application Discontinuation
- 2007-11-23 CL CL200703352A patent/CL2007003352A1/es unknown
- 2007-11-23 TW TW096144409A patent/TW200829581A/zh unknown
- 2007-11-23 AR ARP070105204A patent/AR063912A1/es not_active Application Discontinuation
2009
- 2009-05-19 IL IL198819A patent/IL198819A0/en unknown
- 2009-05-20 TN TNP2009000199A patent/TN2009000199A1/fr unknown
- 2009-06-09 CR CR10847A patent/CR10847A/es unknown
- 2009-06-10 MA MA31977A patent/MA30985B1/fr unknown
- 2009-06-23 EC EC2009009461A patent/ECSP099461A/es unknown
- 2009-06-24 NO NO20092415A patent/NO20092415L/no not_active Application Discontinuation
- 2009-06-24 CO CO09065607A patent/CO6231035A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2007322608A1 (en)	2008-05-29
BRPI0719060A2 (pt)	2014-02-04
IL198819A0 (en)	2010-02-17
CO6231035A2 (es)	2010-12-20
CA2670404A1 (fr)	2008-05-29
EP2074117A2 (fr)	2009-07-01
CL2007003352A1 (es)	2008-07-04
MA30985B1 (fr)	2009-12-01
AU2007322608A2 (en)	2009-07-16
US20080207654A1 (en)	2008-08-28
CR10847A (es)	2009-07-13
WO2008062905A2 (fr)	2008-05-29
TW200829581A (en)	2008-07-16
JP2010510962A (ja)	2010-04-08
MX2009005449A (es)	2009-06-02
ECSP099461A (es)	2009-11-30
EA200970510A1 (ru)	2009-12-30
PE20081228A1 (es)	2008-10-29
EP2256115A1 (fr)	2010-12-01
US20100056526A1 (en)	2010-03-04
AR063912A1 (es)	2009-02-25
KR20090085117A (ko)	2009-08-06
WO2008062905A3 (fr)	2008-12-04
NO20092415L (no)	2009-08-17

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WO2008062905A3 (fr)	2008-12-04	Composé hétéromonocyclique et ses utilisations
TN2012000152A1 (en)	2013-12-12	Spiropiperidine compounds and pharmaceutical use thereof for treating diabetes
UY31803A (es)	2009-12-14	Compuesto cristalino
CO6382126A2 (es)	2012-02-15	Compuestos heteroaromaticos fusionados y espirociclicos para el tratamiento de infecciones bacterianas
MY168201A (en)	2018-10-15	Agricultural And Horticultural Fungicidal Composition
MY148429A (en)	2013-04-30	Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with benzyl groups, method for producing drugs containing said compounds and use thereof
PH12012500903A1 (en)	2014-09-24	N1 - pyrazolospiroketone acetyl-coa carboxylase inhibitors
TN2012000248A1 (en)	2013-12-12	Novel spiropiperidine compounds
PH12013500880A1 (en)	2013-07-01	Pyrazole aminopyrimidine derivatives as lrrk2 modulators
MX340490B (es)	2016-07-11	Derivados de pirazolo [1, 5a] pirimidina y de tieno [3, 2b] pirimidina como moduladores de la cinasa asociada al receptor de la interleucina 4 (irak4).
MX2014006026A (es)	2014-06-04	Derivados de aminopirimidina como moduladores de proteina cinasa 2 rica en unidades repetitivas de leucina (lrrk2).
JO2741B1 (en)	2014-03-15	Spiro-cyclic nitroblast as protease inhibitors
SG176628A1 (en)	2012-01-30	Aminopyrrolidinone derivatives and uses thereof
NO20091858L (no)	2009-07-08	Hydrobenzamid derivater som inhibitorer av HSP90
GEP20166481B (en)	2016-05-25	(crystalline forms of hydrochloride salt of (4a-r, 9a-s)-1-(1h-benzoimidazole-5-carbonyl)-2, 3, 4, 4a, 9, 9a-hexa- hydro-1h-indeno [2, 1-b] pyridine-6-carbonitrile and their use as hsd 1 inhibitors
GEP20166483B (en)	2016-05-25	Phenyl-3-aza-bicyclo[3.1.0] hex-3-yl-methanones and the use thereof as medicament
WO2007108936A3 (fr)	2007-11-01	Azacyclylamines avec substitution n en tant qu'antagonistes de l'histamine-3
NO20082096L (no)	2008-05-29	Azaindol-2-karboksamidderivativer
UA109290C2 (uk)	2015-08-10	Спільні кристали і солі інгібіторів ccr3
MX2010002899A (es)	2010-04-09	Derivados de azaciclilisoquinolinona e isoindolinona como antagonistas de la histamina-3.
GEP20135806B (en)	2013-04-10	Lactams as beta secretase inhibitors
WO2007136668A3 (fr)	2008-01-24	N-benzoyle et n-benzylpyrrolidin-3-ylamines comme antagonistes de l'histamine-3
EA200700909A1 (ru)	2007-12-28	Азаиндолкарбоксамиды
JO2999B1 (ar)	2016-09-05	مركب ثلاثي حلقي و استخدامه الدوائي
MX2008011576A (es)	2008-09-22	Compuestos de imidazo[2,1-b]tiazol sustituidos y su uso para la produccion de farmacos.