TR199800577A2 - Orto-Ikameli benzoilguanidin'ler, bunlarin üretim usülü. - Google Patents

Orto-Ikameli benzoilguanidin'ler, bunlarin üretim usülü.

Info

Publication number
TR199800577A2
TR199800577A2 TR1998/00577A TR9800577A TR199800577A2 TR 199800577 A2 TR199800577 A2 TR 199800577A2 TR 1998/00577 A TR1998/00577 A TR 1998/00577A TR 9800577 A TR9800577 A TR 9800577A TR 199800577 A2 TR199800577 A2 TR 199800577A2
Authority
TR
Turkey
Prior art keywords
bunlar
benzoilguanidin
benkameli
retim
orto
Prior art date
Application number
TR1998/00577A
Other languages
English (en)
Inventor
Andreas Weichert Dr.
Joachim Brendel Dr.
Heinz-Werner Kleemann Dr.
Hans Jochen Lang Dr.
Jan-Robert Schwark Dr.
Udo Albus Dr.
Wolfgang Scholz Dr.
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of TR199800577A2 publication Critical patent/TR199800577A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Formül I'e göre benzoilguanidinler, formülde R(1) ile R(4) istemlerde tanimlandigi gibidir, enfarktüs profilaksi ve enfarktüs tedavisi ve ayrica anjina pectoris tedavisi için kardiyo protektif komponentlere sahip antiaritmik ilaç olarak uygundurlar. Sözkonusu bilesikler isemik kaynakli hasarlarin, özellikle isemik kaynakli kalp aritmilerinin olusumundaki patofizyolojik olaylari önlemektedirler.
TR1998/00577A 1997-04-01 1998-03-30 Orto-Ikameli benzoilguanidin'ler, bunlarin üretim usülü. TR199800577A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19713427A DE19713427A1 (de) 1997-04-01 1997-04-01 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
TR199800577A2 true TR199800577A2 (tr) 1998-10-21

Family

ID=7825126

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00577A TR199800577A2 (tr) 1997-04-01 1998-03-30 Orto-Ikameli benzoilguanidin'ler, bunlarin üretim usülü.

Country Status (29)

Country Link
US (1) US6075054A (tr)
EP (1) EP0869116B1 (tr)
JP (1) JP4160650B2 (tr)
KR (1) KR19980080899A (tr)
CN (1) CN1097579C (tr)
AR (1) AR011207A1 (tr)
AT (1) ATE210636T1 (tr)
AU (1) AU729230B2 (tr)
BR (1) BR9800989A (tr)
CA (1) CA2232461A1 (tr)
CZ (1) CZ290041B6 (tr)
DE (2) DE19713427A1 (tr)
DK (1) DK0869116T3 (tr)
ES (1) ES2169453T3 (tr)
HR (1) HRP980169B1 (tr)
HU (1) HUP9800745A3 (tr)
ID (1) ID19397A (tr)
IL (1) IL123874A (tr)
MY (1) MY117500A (tr)
NO (1) NO309033B1 (tr)
NZ (1) NZ330076A (tr)
PL (1) PL189605B1 (tr)
PT (1) PT869116E (tr)
RU (1) RU2227796C2 (tr)
SI (1) SI0869116T1 (tr)
SK (1) SK282350B6 (tr)
TR (1) TR199800577A2 (tr)
TW (1) TW574192B (tr)
ZA (1) ZA982688B (tr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19951702A1 (de) * 1999-10-27 2001-05-03 Aventis Pharma Gmbh Verwendung von 2-Amino-3,4-dihydro-chinazolinen zur Herstellung eines Medikaments zur Behandlung oder Prophylaxe von durch ischämischen Zuständen bewirkten Krankheiten
OA13285A (en) * 2003-11-13 2007-01-31 Sanofi Aventis Deutschland Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4327244A1 (de) * 1993-08-13 1995-02-16 Hoechst Ag Harnstoffsubstituierte Benzoylguandine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4430212A1 (de) * 1994-08-28 1996-02-29 Merck Patent Gmbh Ortho-substituierte Benzoesäure-Derivate
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
DE19606509A1 (de) * 1996-02-22 1997-08-28 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19624178A1 (de) * 1996-06-18 1998-01-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
EP0869116A1 (de) 1998-10-07
MY117500A (en) 2004-07-31
DE19713427A1 (de) 1998-10-08
KR19980080899A (ko) 1998-11-25
SI0869116T1 (en) 2002-06-30
CA2232461A1 (en) 1998-10-01
PT869116E (pt) 2002-06-28
RU2227796C2 (ru) 2004-04-27
ES2169453T3 (es) 2002-07-01
NO981446L (no) 1998-10-02
IL123874A (en) 2003-11-23
AU5972298A (en) 1998-10-08
AR011207A1 (es) 2000-08-02
ATE210636T1 (de) 2001-12-15
NO981446D0 (no) 1998-03-31
NZ330076A (en) 1999-08-30
CN1194976A (zh) 1998-10-07
ZA982688B (en) 1998-10-01
CZ290041B6 (cs) 2002-05-15
ID19397A (id) 1998-07-09
DE59802390D1 (de) 2002-01-24
CN1097579C (zh) 2003-01-01
AU729230B2 (en) 2001-01-25
HUP9800745A2 (hu) 1998-12-28
JP4160650B2 (ja) 2008-10-01
PL325670A1 (en) 1998-10-12
SK41698A3 (en) 1999-04-13
SK282350B6 (sk) 2002-01-07
JPH10298157A (ja) 1998-11-10
HRP980169A2 (en) 1998-12-31
CZ97698A3 (cs) 1998-11-11
DK0869116T3 (da) 2002-04-08
PL189605B1 (pl) 2005-08-31
HRP980169B1 (en) 2002-06-30
BR9800989A (pt) 2000-02-29
IL123874A0 (en) 1998-10-30
EP0869116B1 (de) 2001-12-12
NO309033B1 (no) 2000-12-04
HUP9800745A3 (en) 2000-03-28
TW574192B (en) 2004-02-01
US6075054A (en) 2000-06-13

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