TR199802426T2 - Taksus türünün hücre kültürleriyle taksanlarin arttirilmis üretimi. - Google Patents

Taksus türünün hücre kültürleriyle taksanlarin arttirilmis üretimi.

Info

Publication number
TR199802426T2
TR199802426T2 TR1998/02426T TR9802426T TR199802426T2 TR 199802426 T2 TR199802426 T2 TR 199802426T2 TR 1998/02426 T TR1998/02426 T TR 1998/02426T TR 9802426 T TR9802426 T TR 9802426T TR 199802426 T2 TR199802426 T2 TR 199802426T2
Authority
TR
Turkey
Prior art keywords
taxus
taxol
efficiency
species
enhancing agents
Prior art date
Application number
TR1998/02426T
Other languages
English (en)
Inventor
Bringi Venkataraman
G. Kadkrade Prakash
L. Prince Christopher
L. Roach Braden
Original Assignee
Phyton, Inc..
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24619244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR199802426(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Phyton, Inc.. filed Critical Phyton, Inc..
Publication of TR199802426T2 publication Critical patent/TR199802426T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P15/00—Preparation of compounds containing at least three condensed carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

Mevcut bulus; sayesinde brevifolia, canadensis, cuspidata, baccata, globosa, floridana, wallichiana, media ve chinensis gibi bilinen bütün Taksus (Taxus) türlerinden taksol, baccatin III ve diger taksol benzeri bilesiklerin veya taksanlarin çok yüksek verimde üretilebildigi metotlar saglanmaktadir. Kültür sartlarinin özel modifikasyonlari (yani ortam bilesimi ve isletme modlari) bütün Taksus türlerinin hücre kültüründen çesitli taksanlarin verimini arttirmak için bulunmustur. Özellikle tercih edilen arttirma ajanlari gümüs iyonu veya kompleksi, jasmonik asit (özellikle metil ester), oksinle (auxin) ilgili gelisim düzenleyicileri ve 3,4- metilendioksi-6-nitrosinnamik asit gibi fenilpropanoid kimyasal degisim inhibitörleri içermektedir. Bu arttirma ajanlari tek basina veya bir baska veya diger verim arttici sartlarla kombine olarak kullanilabilmektedir.
TR1998/02426T 1996-05-24 1997-05-27 Taksus türünün hücre kültürleriyle taksanlarin arttirilmis üretimi. TR199802426T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65303696A 1996-05-24 1996-05-24

Publications (1)

Publication Number Publication Date
TR199802426T2 true TR199802426T2 (tr) 2001-01-22

Family

ID=24619244

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/02426T TR199802426T2 (tr) 1996-05-24 1997-05-27 Taksus türünün hücre kültürleriyle taksanlarin arttirilmis üretimi.

Country Status (16)

Country Link
US (2) US8338143B2 (tr)
EP (3) EP1538214A1 (tr)
JP (5) JP4047929B2 (tr)
KR (7) KR20070094867A (tr)
AT (1) ATE315097T1 (tr)
AU (1) AU727425B2 (tr)
BR (1) BR9709361B1 (tr)
CA (2) CA2638292A1 (tr)
DE (1) DE69735059T2 (tr)
DK (1) DK0954596T3 (tr)
ES (1) ES2256887T3 (tr)
HU (2) HU223267B1 (tr)
IL (1) IL127062A (tr)
PT (1) PT954596E (tr)
TR (1) TR199802426T2 (tr)
WO (1) WO1997044476A1 (tr)

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CN105349592B (zh) * 2015-12-09 2018-11-27 天津艾赛博生物技术有限公司 代谢互补的植物细胞系混种培养生产次级代谢产物的方法
CN106636242A (zh) * 2016-12-20 2017-05-10 天津艾赛博生物技术有限公司 一种红豆杉细胞长期培养生产紫杉烷的调控方法
JP7359527B2 (ja) * 2017-05-31 2023-10-11 トヨタ自動車株式会社 電池搭載構造
WO2022026613A2 (en) * 2020-07-28 2022-02-03 Impello Biosciences, Inc. Methods and compositions for altering secondary metabolites in plants
CN113416689B (zh) * 2021-08-04 2023-01-10 海南鑫开源医药科技有限公司 一种利用植物细胞发酵技术生产高丽槐素的方法
CN115948494B (zh) * 2022-09-12 2024-07-16 昆明理工大学 一种利用三七细胞合成齐墩果烷型皂苷的方法
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Also Published As

Publication number Publication date
US8338143B2 (en) 2012-12-25
WO1997044476A1 (en) 1997-11-27
US20110086397A1 (en) 2011-04-14
DE69735059D1 (de) 2006-03-30
PT954596E (pt) 2006-05-31
JP2008167764A (ja) 2008-07-24
CA2638292A1 (en) 1997-11-27
BR9709361B1 (pt) 2009-05-05
CA2256357A1 (en) 1997-11-27
KR20000015952A (ko) 2000-03-25
KR20120138251A (ko) 2012-12-24
JP2007143557A (ja) 2007-06-14
KR20100070389A (ko) 2010-06-25
JP2011212029A (ja) 2011-10-27
EP1538214A1 (en) 2005-06-08
CA2256357C (en) 2008-08-12
IL127062A0 (en) 1999-09-22
JP2000511420A (ja) 2000-09-05
HUP9901788A2 (hu) 1999-09-28
AU727425B2 (en) 2000-12-14
KR20090005241A (ko) 2009-01-12
EP0954596B1 (en) 2006-01-04
KR20140062179A (ko) 2014-05-22
KR20070094867A (ko) 2007-09-21
BR9709361A (pt) 1999-08-10
EP1398384A1 (en) 2004-03-17
ATE315097T1 (de) 2006-02-15
KR20100070388A (ko) 2010-06-25
IL127062A (en) 2005-09-25
US20130017582A1 (en) 2013-01-17
HUP9901788A3 (en) 2002-07-29
HU223267B1 (hu) 2004-04-28
EP0954596A1 (en) 1999-11-10
JP4047929B2 (ja) 2008-02-13
AU3143097A (en) 1997-12-09
JP2013046643A (ja) 2013-03-07
HU0302357D0 (en) 2003-09-29
ES2256887T3 (es) 2006-07-16
DK0954596T3 (da) 2006-05-15
DE69735059T2 (de) 2006-08-31
KR100897457B1 (ko) 2009-12-18

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