TR199802441A2 - Kanda asiri ürik asit bulunmasinin tedavisi ve önlenmesi için yöntem ve terkip. - Google Patents
Kanda asiri ürik asit bulunmasinin tedavisi ve önlenmesi için yöntem ve terkip.Info
- Publication number
- TR199802441A2 TR199802441A2 TR1998/02441A TR9802441A TR199802441A2 TR 199802441 A2 TR199802441 A2 TR 199802441A2 TR 1998/02441 A TR1998/02441 A TR 1998/02441A TR 9802441 A TR9802441 A TR 9802441A TR 199802441 A2 TR199802441 A2 TR 199802441A2
- Authority
- TR
- Turkey
- Prior art keywords
- treatment
- blood
- uric acid
- prevention
- composition
- Prior art date
Links
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title abstract 2
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008280 blood Substances 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title abstract 2
- 229940116269 uric acid Drugs 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 201000005569 Gout Diseases 0.000 abstract 1
- 201000001431 Hyperuricemia Diseases 0.000 abstract 1
- 206010022489 Insulin Resistance Diseases 0.000 abstract 1
- 208000009625 Lesch-Nyhan syndrome Diseases 0.000 abstract 1
- 208000035317 Total hypoxanthine-guanine phosphoribosyl transferase deficiency Diseases 0.000 abstract 1
- 206010046337 Urate nephropathy Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- GXPHKUHSUJUWKP-UHFFFAOYSA-N troglitazone Chemical compound C1CC=2C(C)=C(O)C(C)=C(C)C=2OC1(C)COC(C=C1)=CC=C1CC1SC(=O)NC1=O GXPHKUHSUJUWKP-UHFFFAOYSA-N 0.000 abstract 1
- 229960001641 troglitazone Drugs 0.000 abstract 1
- GXPHKUHSUJUWKP-NTKDMRAZSA-N troglitazone Natural products C([C@@]1(OC=2C(C)=C(C(=C(C)C=2CC1)O)C)C)OC(C=C1)=CC=C1C[C@H]1SC(=O)NC1=O GXPHKUHSUJUWKP-NTKDMRAZSA-N 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Biological Depolymerization Polymers (AREA)
Abstract
Troglitazon gibi ensülin duyarliligini artiran maddelerin, hiperüriseminin yani kanda asiri ürik asit bulunmasini tedavi ve önleme kabiliyeti oldugundan gut, üriner sistemde tas olusmasi, hiperürisemik nefropati ve Lesch-Nyhan sendromu gibi hastaliklarin tedavisi ve önleyici tedavisinde kullanilabilirler.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32318297 | 1997-11-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TR199802441A3 TR199802441A3 (tr) | 1999-10-21 |
| TR199802441A2 true TR199802441A2 (tr) | 1999-10-21 |
Family
ID=18151987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1998/02441A TR199802441A2 (tr) | 1997-11-25 | 1998-11-25 | Kanda asiri ürik asit bulunmasinin tedavisi ve önlenmesi için yöntem ve terkip. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6353009B1 (tr) |
| EP (1) | EP0919232B1 (tr) |
| KR (1) | KR19990045531A (tr) |
| AR (1) | AR011231A1 (tr) |
| AT (1) | ATE278400T1 (tr) |
| AU (1) | AU744653B2 (tr) |
| BR (1) | BR9805012A (tr) |
| CA (1) | CA2254394C (tr) |
| CZ (1) | CZ378898A3 (tr) |
| DE (2) | DE69826811D1 (tr) |
| ES (1) | ES2230657T3 (tr) |
| HU (2) | HUP9902721A2 (tr) |
| ID (1) | ID21332A (tr) |
| IL (1) | IL127219A (tr) |
| NO (1) | NO985484L (tr) |
| NZ (1) | NZ332895A (tr) |
| PL (1) | PL329893A1 (tr) |
| RU (1) | RU2190425C2 (tr) |
| SA (1) | SA99191266A (tr) |
| TR (1) | TR199802441A2 (tr) |
| TW (1) | TW592697B (tr) |
| ZA (1) | ZA9810788B (tr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312807A (zh) | 1998-06-19 | 2001-09-12 | 希龙公司 | 糖元合成酶激酶3的抑制剂 |
| US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| US6794154B1 (en) * | 1999-05-27 | 2004-09-21 | Tanabe Seiyaku Co., Ltd. | Remedies for kidney diseases and method for screening the same |
| US6768008B2 (en) | 2000-04-24 | 2004-07-27 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| US6680387B2 (en) | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| US6958355B2 (en) | 2000-04-24 | 2005-10-25 | Aryx Therapeutics, Inc. | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| WO2002024689A1 (en) * | 2000-09-21 | 2002-03-28 | Aryx Therapeutics | Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, and atherosclerosis |
| ATE529110T1 (de) * | 2002-03-05 | 2011-11-15 | Transtech Pharma Inc | Mono- und bicyclische azolderivate die die interaktion von liganden mit rage hemmen |
| RU2230565C1 (ru) * | 2003-03-31 | 2004-06-20 | Савина Лидия Васильевна | Способ снижения уровня мочевой кислоты в организме человека |
| CN1805743A (zh) * | 2003-05-20 | 2006-07-19 | 特兰斯泰克制药公司 | 用作逆转淀粉样变性及其他与之相关疾病的rage拮抗剂 |
| US20050025823A1 (en) * | 2003-07-29 | 2005-02-03 | Fong Andy A.T. | Methods of use of herbal compositions |
| JP2005092923A (ja) * | 2003-09-12 | 2005-04-07 | Renesas Technology Corp | 半導体記憶装置 |
| WO2006012438A2 (en) * | 2004-07-21 | 2006-02-02 | University Of Florida Research Foundation, Inc. | Compositions and methods for treatment and prevention of insulin resistance |
| AU2006276933A1 (en) * | 2005-07-21 | 2007-02-15 | University Of Florida Research Foundation, Inc. | Compositions and methods for treatment and prevention of hyperuricemia related health consequences |
| BRPI0809643A2 (pt) * | 2007-04-05 | 2014-11-11 | Daiichi Sankyo Co Ltd | Derivados de heteroarila bicíclica fundida |
| RU2366421C2 (ru) * | 2007-11-01 | 2009-09-10 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтический состав для лечения диабета |
| ES2617191T3 (es) | 2009-03-05 | 2017-06-15 | Daiichi Sankyo Company, Limited | Derivado de piridina como inhibidor de PPARY |
| JP5805646B2 (ja) | 2009-09-30 | 2015-11-04 | ブイティーブイ・セラピューティクス・エルエルシー | アルツハイマー病の治療のための置換イミダゾール誘導体 |
| US8822464B2 (en) | 2011-11-28 | 2014-09-02 | Boehringer Ingelheim International Gmbh | N-aryl-piperazine derivatives and their use as positive allosteric modulators of mGluR5 receptors |
| US8741892B2 (en) | 2011-12-05 | 2014-06-03 | Boehringer Ingelheim International Gmbh | Compounds |
| US8846948B2 (en) | 2011-12-13 | 2014-09-30 | Boehringer Ingelheim International Gmbh | Compounds |
| US8796467B2 (en) | 2011-12-13 | 2014-08-05 | Boehringer Ingelheim International Gmbh | Compounds |
| US8716277B2 (en) * | 2011-12-14 | 2014-05-06 | Boehringer Ingelheim International Gmbh | Substituted imidazole compounds useful as positive allosteric modulators of mGlu5 receptor activity |
| US8937176B2 (en) | 2011-12-14 | 2015-01-20 | Boehringer Ingelheim International Gmbh | Compounds |
| US8883789B2 (en) | 2011-12-14 | 2014-11-11 | Boehringer Ingelheim International Gmbh | Piperazine derivatives and their use as positive allosteric modulators of mGluR5 receptors |
| US8889677B2 (en) | 2012-01-17 | 2014-11-18 | Boehringer Ingellheim International GmbH | Substituted triazoles useful as mGlu5 receptor modulators |
| MX2014008484A (es) * | 2012-01-27 | 2014-10-14 | Teijin Pharma Ltd | Agente terapeutico para la diabetes mellitus. |
| US20190152967A1 (en) * | 2016-04-04 | 2019-05-23 | The Schepens Eye Research Institute, Inc. | Peroxisome proliferator-activated receptor gamma selective agonists for inhibition of retinal pigment epithelium degeneration or geographic atrophy |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| JPS58118577A (ja) | 1982-01-07 | 1983-07-14 | Takeda Chem Ind Ltd | チアゾリジン誘導体 |
| JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
| CN1003445B (zh) | 1984-10-03 | 1989-03-01 | 武田药品工业株式会社 | 噻唑烷二酮衍生物,其制备方法和用途 |
| AR240698A1 (es) | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
| HU210339B (en) | 1985-05-21 | 1995-03-28 | Pfizer | Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect |
| ZA873745B (en) | 1986-06-04 | 1988-10-26 | Daiichi Seiyaku Co | Benzopyran derivatives |
| US4873255A (en) | 1987-02-04 | 1989-10-10 | Sankyo Company Limited | Thiazolidinone derivatives, their preparation and their use |
| FI91869C (fi) | 1987-03-18 | 1994-08-25 | Tanabe Seiyaku Co | Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi |
| EP0295828A1 (en) | 1987-06-13 | 1988-12-21 | Beecham Group Plc | Novel compounds |
| US5194443A (en) | 1987-09-04 | 1993-03-16 | Beecham Group P.L.C. | Compounds |
| US5260445A (en) | 1987-09-04 | 1993-11-09 | Beecham Group P.L.C. | 2,4-thiazolidinediones |
| US5232925A (en) | 1987-09-04 | 1993-08-03 | Beecham Group P.L.C. | Compounds |
| EP0842925A1 (en) | 1987-09-04 | 1998-05-20 | Beecham Group Plc | Substituted thiazolidinedione derivatives |
| US5061717A (en) | 1988-03-08 | 1991-10-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
| US5223522A (en) | 1988-03-08 | 1993-06-29 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
| WO1989008651A1 (en) | 1988-03-08 | 1989-09-21 | Pfizer Inc. | Hypoglycemic thiazolidinedione derivatives |
| US5120754A (en) | 1988-03-08 | 1992-06-09 | Pfizer Inc. | Thiazolidinedione hypoglycemic agents |
| US5155114A (en) * | 1989-01-23 | 1992-10-13 | Fujisawa Pharmaceutical Company, Ltd. | Method of treatment using pyrazolopyridine compound |
| US4897405A (en) | 1989-04-21 | 1990-01-30 | American Home Products Corporation | Novel naphthalenylalkyl-3H-1,2,3,5-oxathiadiazole 2-oxides useful as antihyperglycemic agents |
| GB8919434D0 (en) | 1989-08-25 | 1989-10-11 | Beecham Group Plc | Novel compounds |
| WO1991007107A1 (en) | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
| JPH0469383A (ja) | 1990-07-06 | 1992-03-04 | Yamanouchi Pharmaceut Co Ltd | 置換チアゾリジン誘導体 |
| GB9017218D0 (en) | 1990-08-06 | 1990-09-19 | Beecham Group Plc | Novel compounds |
| BR9306650A (pt) * | 1992-07-02 | 1998-12-08 | Novo Nordisk As | Processo para a polimerização e/ou modificação enzimática de lignina ou de material contendo lignina por meio do tratamento com uma peroxidase uso do processo e cola ou agente aglutinante ativo |
| GB9223059D0 (en) | 1992-11-04 | 1992-12-16 | Bamford Excavators Ltd | Intercooler apparatus |
| JP2845743B2 (ja) | 1992-12-28 | 1999-01-13 | 三菱化学株式会社 | 新規なナフタレン誘導体 |
| JPH06211657A (ja) | 1993-01-21 | 1994-08-02 | Mochida Pharmaceut Co Ltd | 尿酸排泄剤 |
| CZ283339B6 (cs) | 1993-09-15 | 1998-03-18 | Sankyo Company Limited | Použití thiazolidinových derivátů pro výrobu léčivého přípravku pro léčení zhoršené tolerance glukosy pro zabránění nebo zpoždění nástupu diabetes mellitus nezávislé na inzulinu |
| ATE179709T1 (de) | 1993-12-27 | 1999-05-15 | Japan Tobacco Inc | Isoxazolidindionderivate und deren verwendung |
| RU2151145C1 (ru) | 1994-04-11 | 2000-06-20 | Санкио Компани Лимитед | Промежуточное соединение для получения гетероциклических соединений, обладающих антидиабетической активностью |
| GB9418958D0 (en) * | 1994-09-21 | 1994-11-09 | Ciba Geigy Ag | Fluorescent whitening agents |
| CA2159938A1 (en) | 1994-10-07 | 1996-04-08 | Hiroaki Yanagisawa | Oxime derivatives, their preparation and their therapeutic use |
| CZ293016B6 (cs) | 1995-06-01 | 2004-01-14 | Sankyo Company Limited | Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem |
| US5929055A (en) | 1997-06-23 | 1999-07-27 | The Research Foundation Of State University Of New York | Therapeutic method for management of diabetes mellitus |
-
1997
- 1997-03-25 HU HU9902721A patent/HUP9902721A2/hu unknown
-
1998
- 1998-11-18 ES ES98309426T patent/ES2230657T3/es not_active Expired - Lifetime
- 1998-11-18 DE DE69826811A patent/DE69826811D1/de not_active Expired - Lifetime
- 1998-11-18 US US09/195,031 patent/US6353009B1/en not_active Expired - Fee Related
- 1998-11-18 EP EP98309426A patent/EP0919232B1/en not_active Expired - Lifetime
- 1998-11-18 DE DE69826811T patent/DE69826811T4/de not_active Expired - Lifetime
- 1998-11-18 AT AT98309426T patent/ATE278400T1/de not_active IP Right Cessation
- 1998-11-19 NZ NZ332895A patent/NZ332895A/en unknown
- 1998-11-20 CZ CZ983788A patent/CZ378898A3/cs unknown
- 1998-11-23 IL IL12721998A patent/IL127219A/en not_active IP Right Cessation
- 1998-11-24 BR BR9805012A patent/BR9805012A/pt not_active Application Discontinuation
- 1998-11-24 NO NO985484A patent/NO985484L/no not_active Application Discontinuation
- 1998-11-24 CA CA002254394A patent/CA2254394C/en not_active Expired - Fee Related
- 1998-11-24 TW TW087119452A patent/TW592697B/zh not_active IP Right Cessation
- 1998-11-24 ID IDP981528A patent/ID21332A/id unknown
- 1998-11-24 RU RU98121310/14A patent/RU2190425C2/ru not_active IP Right Cessation
- 1998-11-24 KR KR1019980050484A patent/KR19990045531A/ko not_active Ceased
- 1998-11-25 HU HU9802721A patent/HUP9802721A1/hu unknown
- 1998-11-25 PL PL98329893A patent/PL329893A1/xx unknown
- 1998-11-25 TR TR1998/02441A patent/TR199802441A2/tr unknown
- 1998-11-25 AR ARP980105979A patent/AR011231A1/es unknown
- 1998-11-25 AU AU94102/98A patent/AU744653B2/en not_active Ceased
- 1998-11-25 ZA ZA9810788A patent/ZA9810788B/xx unknown
-
1999
- 1999-04-06 SA SA99191266A patent/SA99191266A/ar unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2190425C2 (ru) | 2002-10-10 |
| IL127219A (en) | 2001-08-08 |
| KR19990045531A (ko) | 1999-06-25 |
| AR011231A1 (es) | 2000-08-02 |
| ZA9810788B (en) | 1999-05-25 |
| SA99191266A (ar) | 2005-12-03 |
| TR199802441A3 (tr) | 1999-10-21 |
| DE69826811D1 (de) | 2004-11-11 |
| CA2254394C (en) | 2009-11-17 |
| BR9805012A (pt) | 2000-03-21 |
| ID21332A (id) | 1999-05-27 |
| HUP9802721A1 (hu) | 2000-03-28 |
| HU9802721D0 (en) | 1999-01-28 |
| HK1020259A1 (en) | 2000-04-07 |
| CA2254394A1 (en) | 1999-05-25 |
| US6353009B1 (en) | 2002-03-05 |
| ATE278400T1 (de) | 2004-10-15 |
| AU9410298A (en) | 1999-06-17 |
| EP0919232B1 (en) | 2004-10-06 |
| IL127219A0 (en) | 1999-09-22 |
| PL329893A1 (en) | 1999-06-07 |
| CZ378898A3 (cs) | 1999-07-14 |
| TW592697B (en) | 2004-06-21 |
| HUP9902721A2 (hu) | 1999-12-28 |
| NZ332895A (en) | 2001-04-27 |
| NO985484L (no) | 1999-05-26 |
| DE69826811T4 (de) | 2006-09-21 |
| ES2230657T3 (es) | 2005-05-01 |
| EP0919232A1 (en) | 1999-06-02 |
| DE69826811T2 (de) | 2005-06-16 |
| NO985484D0 (no) | 1998-11-24 |
| AU744653B2 (en) | 2002-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TR199802441A2 (tr) | Kanda asiri ürik asit bulunmasinin tedavisi ve önlenmesi için yöntem ve terkip. | |
| MXPA04004170A (es) | Tratamiento del sindrome de resitencia a la insulina y diabetes de tipo 2 con inhibidores de pde9. | |
| DE69826695D1 (de) | Arylharnstoffderivate zur behandlung von inflammatorischen oder immunomodulatorischen erkrankungen | |
| TR200103493T2 (tr) | Metaloproteaz önleyicileri | |
| ATE381336T1 (de) | Verwendung von a2a adenosin rezeptor agonisten und anti-pathogene mittel enthaltenden kombinationen zur behandlung von entzündungskrankheiten | |
| NO20051107L (no) | Substituerte tienylhydroksaminsyrer og deres anvendelse til behandling av sykdommer forbundet med enzymatisk histondeacetylueaktivitet | |
| ATE409466T1 (de) | Verfahren und zusammensetzung zur behandlung von diabetes, hypertonie, chronischer herzinsuffizienz und mit flüssigkeitsretention einhergehenden zuständen | |
| Motzkau et al. | Expression of matrix-metalloproteases in the fluid of chronic diabetic foot wounds treated with a protease absorbent dressing | |
| ATE303147T1 (de) | Verwendung von thiazolidinedion-derivaten zur behandlung des polyzystischen ovarien syndroms und des schwangerschaftsdiabetes | |
| ID30237A (id) | KOMBINASI PENGHAMBAT-PENGHAMBAT FBPase DAN PEMEKA-PEMEKA INSULIN UNTUK PENGOBATAN DIABETES | |
| DE60324777D1 (de) | Verwendung von il-18-inhibitoren zur behandlung und/oder prävention von peripheren gefässkrankheiten | |
| WO2003024386A8 (en) | Use of potent, selective and non toxic c-kit inhibitors for treating interstitial cystitis | |
| DE60229406D1 (de) | Verfahren zur behandlung oder verhinderung von vaskulärer entzündung mit sterol-absorbierungs- inhibitor(en) | |
| ATE311192T1 (de) | Verfahren zur behandlung von chronischen geschwüren | |
| EP1720574A4 (en) | METHOD FOR THE TREATMENT OF ABNORMAL CELL GROWTH WITH C-MET AND TOR HEMMERN | |
| NO994640D0 (no) | Hostestillende midler | |
| WO2002039994A3 (en) | Methods for the treatment and prevention of urinary stone disease | |
| DE60116642D1 (de) | Verbindungen mit cytochrom p450ra1 hemmenden aktivität | |
| BR0213994A (pt) | Derivados heterocìclicos de glicinamida e seus usos médicos | |
| MA26777A1 (fr) | Inhibiteurs d'aminotransferase dependante d'aminoacide en chaine ramifiee et leur usage dans le traitement de la retinopathie diabetique. | |
| ATE327752T1 (de) | Aryl- (oder heteroaryl-) azolylcarbynolderivatve zur behandlung von harninkontinenz | |
| DK1441708T3 (da) | Sammensætninger og fremgangsmåder til forögelse af föjelighed med terapier ved anvendelse af aldehyddehydrogenase-inhibitorer og behandling af alkoholisme | |
| DE69721747D1 (de) | Methode zur behandlung oder verhütung von interstitieller blasenentzundung | |
| MXPA02004699A (es) | Derivados de acidos hidroxieicosatetraenoico modificados con cadena omega y metodos de su uso para el tratameinto del ojo reseco. | |
| NO20012569L (no) | Anvendelse av aryl-substituerte syklobutylalkylaminer for behandling av urininkontinens |