TR200002019T2 - 1,3,4-Okzadiazolon türevleri. - Google Patents

1,3,4-Okzadiazolon türevleri.

Info

Publication number
TR200002019T2
TR200002019T2 TR2000/02019T TR200002019T TR200002019T2 TR 200002019 T2 TR200002019 T2 TR 200002019T2 TR 2000/02019 T TR2000/02019 T TR 2000/02019T TR 200002019 T TR200002019 T TR 200002019T TR 200002019 T2 TR200002019 T2 TR 200002019T2
Authority
TR
Turkey
Prior art keywords
formula
oxadiazolone derivatives
oxadiazolone
derivatives
solvate
Prior art date
Application number
TR2000/02019T
Other languages
English (en)
Inventor
Hewawasam Piyasena
Ding Min
E. Jr. Starrett John
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of TR200002019T2 publication Critical patent/TR200002019T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Mevcut bulus; yüksek ölçüde iletkenlige sahip kalsiyum-aktivasyonlu potasyum kanallarinin açilmasinin sorumlulugundaki rahatsizliklarin tedavisinde faydali olan, içerisinde A,B,D ve R' nin yukarida tanimlandigi gibi oldugu genel formüle Formül (I) sahip, yeni okzadiazolon türevlerini veya bunlarin toksik olmayan, farmasötik olarak kabul edilebilen bir tuzu veya solvatini saglamaktadir.
TR2000/02019T 1998-01-29 1999-01-15 1,3,4-Okzadiazolon türevleri. TR200002019T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7296698P 1998-01-29 1998-01-29
US10227498P 1998-09-29 1998-09-29

Publications (1)

Publication Number Publication Date
TR200002019T2 true TR200002019T2 (tr) 2000-11-21

Family

ID=26753969

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02019T TR200002019T2 (tr) 1998-01-29 1999-01-15 1,3,4-Okzadiazolon türevleri.

Country Status (27)

Country Link
US (1) US6034113A (tr)
EP (1) EP1051173A4 (tr)
JP (1) JP2002527352A (tr)
KR (1) KR20010077838A (tr)
CN (1) CN1150175C (tr)
AR (1) AR010712A1 (tr)
AU (1) AU735704B2 (tr)
BG (1) BG104706A (tr)
BR (1) BR9913010A (tr)
CA (1) CA2318830A1 (tr)
CO (1) CO5090837A1 (tr)
EE (1) EE04089B1 (tr)
GE (1) GEP20032914B (tr)
HU (1) HUP0102025A3 (tr)
ID (1) ID26909A (tr)
IL (1) IL137518A0 (tr)
LT (1) LT4838B (tr)
LV (1) LV12559B (tr)
NO (1) NO317102B1 (tr)
NZ (1) NZ505409A (tr)
PL (1) PL342060A1 (tr)
RU (1) RU2202548C2 (tr)
SK (1) SK10852000A3 (tr)
TR (1) TR200002019T2 (tr)
TW (1) TW550075B (tr)
UA (1) UA58579C2 (tr)
WO (1) WO1999038510A1 (tr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1056731A4 (en) * 1998-01-29 2002-07-31 Bristol Myers Squibb Co AMINOACID DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE
CN1133636C (zh) * 1999-01-29 2004-01-07 布里斯托尔-米尔斯·斯奎布公司 二芳基1,3,4－噁二唑酮的氨基甲酸酯衍生物
US6297241B1 (en) 1999-01-29 2001-10-02 Bristol-Myers Squibb Company Carbamate derivatives of diaryl 1,3,4-oxadiazolone
US6326388B1 (en) * 1999-12-21 2001-12-04 Celgene Corporation Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level
CA2438868A1 (en) 2001-02-20 2002-09-19 Valentin K. Gribkoff Modulators of kcnq potassium channels and use thereof in treating migraine and mechanistically related diseases
WO2002083111A2 (en) * 2001-04-16 2002-10-24 Tanabe Seiyaku Co., Ltd. Imidazole, thiazole and oxazole derivatives and their use for the manufacture of a medicament for the treatment and/or prevention of pollakiuria or urinary incontinence
US6909027B1 (en) * 2001-08-13 2005-06-21 Perry Robins Method of forming an in-situ film dressing and the composition of the film-forming material
US7119246B2 (en) * 2002-06-25 2006-10-10 Perry Robins Method of treating acne
CN116898848A (zh) 2012-01-18 2023-10-20 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
JP5855599B2 (ja) * 2013-04-30 2016-02-09 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
CN104710379B (zh) * 2015-03-09 2017-01-18 华南理工大学 一种bms‑191011的合成方法
JP6165816B2 (ja) * 2015-10-01 2017-07-19 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
CN110545809A (zh) * 2017-02-24 2019-12-06 奥维德医疗公司 治疗发作性疾病的方法
WO2020086149A1 (en) 2018-10-26 2020-04-30 University Of South Florida Drug for treating tinnitus
CN110987847B (zh) * 2019-12-11 2021-02-19 苏州今蓝纳米科技有限公司 1,3,4-噁二唑衍生物在检测酸以及数据加密和储存中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH583213A5 (tr) * 1973-05-21 1976-12-31 Ciba Geigy Ag
IT1251488B (it) * 1991-09-17 1995-05-15 Mini Ricerca Scient Tecnolog Ossa(tia)diazol- e triazol-oni(tioni) ad attivita' acaricida ed insetticida
US5234947A (en) * 1991-11-07 1993-08-10 New York University Potassium channel activating compounds and methods of use thereof
US5547966A (en) * 1993-10-07 1996-08-20 Bristol-Myers Squibb Company Aryl urea and related compounds
TW467902B (en) * 1996-07-31 2001-12-11 Bristol Myers Squibb Co Diphenyl heterocycles as potassium channel modulators
EP1056731A4 (en) * 1998-01-29 2002-07-31 Bristol Myers Squibb Co AMINOACID DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE

Also Published As

Publication number Publication date
IL137518A0 (en) 2001-07-24
GEP20032914B (en) 2003-03-25
JP2002527352A (ja) 2002-08-27
LV12559A (en) 2000-11-20
NZ505409A (en) 2003-08-29
CO5090837A1 (es) 2001-10-30
HUP0102025A3 (en) 2002-01-28
TW550075B (en) 2003-09-01
EE04089B1 (et) 2003-08-15
AU735704B2 (en) 2001-07-12
NO20003825L (no) 2000-07-26
CN1150175C (zh) 2004-05-19
EP1051173A4 (en) 2002-07-31
LT4838B (lt) 2001-08-27
BR9913010A (pt) 2001-05-08
WO1999038510A1 (en) 1999-08-05
HUP0102025A2 (hu) 2001-11-28
AU2230899A (en) 1999-08-16
EP1051173A1 (en) 2000-11-15
CA2318830A1 (en) 1999-08-05
KR20010077838A (ko) 2001-08-20
RU2202548C2 (ru) 2003-04-20
BG104706A (en) 2001-04-30
US6034113A (en) 2000-03-07
UA58579C2 (uk) 2003-08-15
CN1289249A (zh) 2001-03-28
LT2000068A (en) 2001-03-26
NO20003825D0 (no) 2000-07-26
SK10852000A3 (sk) 2002-02-05
LV12559B (en) 2001-04-20
NO317102B1 (no) 2004-08-09
ID26909A (id) 2001-02-15
PL342060A1 (en) 2001-05-21
EE200000447A (et) 2001-12-17
AR010712A1 (es) 2000-07-12

Similar Documents

Publication Publication Date Title
TR200002019T2 (tr) 1,3,4-Okzadiazolon türevleri.
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
BG105270A (en) Tetrahydropyridoethers
NZ510987A (en) 3-substituted-4-arylquinolin-2-one derivatives as potassium channel modulators
TR200800474T2 (tr) Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem.
TR200103460T2 (tr) 5-Fenil-pirimidin türevleri
BG103310A (en) Benzonaphthyridins as bronchial therapeutical means
BR9809185A (pt) Diidropiranos fundidos
MXPA02012042A (es) Compuestos efectivos como agonistas de beta-2-adrenorreceptor, y como inhibidores de pde4.
MXPA03002911A (es) Compuestos quimicos.
TR200002605T2 (tr) Nitrik oksit sentaz inhibitörleri olarak faydalı halojene amidino amino asit türevleri
TR200403436T2 (tr) Kristalin 1-metilkarbapenem türevleri.
TR200001452T2 (tr) Bifenilamidin türevleri.
TR200100885T2 (tr) 2-Metil-tieno-benzodiazepin formülasyonu
ATE265455T1 (de) Tetrahydropyridoverbindungen
TR200201128T2 (tr) PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
NZ515025A (en) Solvates of pymetrozine
BR9902084A (pt) Heterociclos.
YU18801A (sh) Eletriptan hidrobromid monohidrat
DK1204659T3 (da) Serotonerge benzofuraner
TR199901386T2 (tr) Imidazopiridazinler.
PT1056754E (pt) Derivados fosfatados de 1,3,4-oxadiazolona de diarilo
ATE330958T1 (de) Pyrazino 1'2':1,6öpyrido 3,4-böindolderivate
PT1121375E (pt) Composto de elevada pureza de (7alfa, 17alfa)-17-hidroxi-7-metil-19-nor-17-pregn-5(10)-en-20-in-3-ona
GB9901253D0 (en) Bis-terpyridine-platinum(II) complexes