TR200100885T2 - 2-Metil-tieno-benzodiazepin formülasyonu - Google Patents
2-Metil-tieno-benzodiazepin formülasyonuInfo
- Publication number
- TR200100885T2 TR200100885T2 TR2001/00885T TR200100885T TR200100885T2 TR 200100885 T2 TR200100885 T2 TR 200100885T2 TR 2001/00885 T TR2001/00885 T TR 2001/00885T TR 200100885 T TR200100885 T TR 200100885T TR 200100885 T2 TR200100885 T2 TR 200100885T2
- Authority
- TR
- Turkey
- Prior art keywords
- thieno
- methyl
- benzodiazepine formulation
- formulation
- benzodiazepine
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- KHXIELCFAHVRAL-UHFFFAOYSA-N 2-methylthieno[2,3-i][1,2]benzodiazepine Chemical compound C12=NN(C)C=CC=C2C=CC2=C1C=CS2 KHXIELCFAHVRAL-UHFFFAOYSA-N 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- IUDQMMSLVSVGDZ-UHFFFAOYSA-N chembl1201741 Chemical class C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2.C1=CC=C2C(CC=3C4=CC=CC=C4C=C(C=3O)C(=O)O)=C(O)C(C(O)=O)=CC2=C1 IUDQMMSLVSVGDZ-UHFFFAOYSA-N 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 239000004005 microsphere Substances 0.000 abstract 1
- 229960005017 olanzapine Drugs 0.000 abstract 1
- KVWDHTXUZHCGIO-UHFFFAOYSA-N olanzapine Chemical compound C1CN(C)CCN1C1=NC2=CC=CC=C2NC2=C1C=C(C)S2 KVWDHTXUZHCGIO-UHFFFAOYSA-N 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bu bulus, olanzapinin farmasötik açidan kabul edilebilir bir yagli veya kolesterol mikro kürecik formülasyonunu saglar.Bulus ayrica,yeni olanzapin pamoat tuzlari veya bunlarin solvatlarini saglar.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16376898A | 1998-09-30 | 1998-09-30 | |
| US09/163,769 US6169084B1 (en) | 1997-09-30 | 1998-09-30 | 2-methyl-thieno-benzodiazepine formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200100885T2 true TR200100885T2 (tr) | 2001-08-21 |
Family
ID=26859927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/00885T TR200100885T2 (tr) | 1998-09-30 | 1999-03-24 | 2-Metil-tieno-benzodiazepin formülasyonu |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP1119359B1 (tr) |
| JP (1) | JP4551988B2 (tr) |
| CN (1) | CN1146422C (tr) |
| AT (2) | ATE359793T1 (tr) |
| AU (1) | AU759751B2 (tr) |
| BR (1) | BR9914156A (tr) |
| CA (1) | CA2344873A1 (tr) |
| CZ (1) | CZ302367B6 (tr) |
| DE (2) | DE69935873T2 (tr) |
| DK (2) | DK1119359T3 (tr) |
| EA (1) | EA002580B1 (tr) |
| ES (2) | ES2221376T3 (tr) |
| GE (1) | GEP20094818B (tr) |
| HK (1) | HK1041199B (tr) |
| HR (1) | HRP20010238B1 (tr) |
| HU (1) | HU227400B1 (tr) |
| ID (1) | ID29574A (tr) |
| IL (2) | IL141766A0 (tr) |
| MY (1) | MY126476A (tr) |
| NO (1) | NO328243B1 (tr) |
| NZ (1) | NZ510208A (tr) |
| PL (1) | PL196821B1 (tr) |
| PT (2) | PT1468689E (tr) |
| SK (1) | SK285944B6 (tr) |
| TR (1) | TR200100885T2 (tr) |
| TW (1) | TW577890B (tr) |
| UA (1) | UA66872C2 (tr) |
| WO (1) | WO2000018408A1 (tr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022698B2 (en) | 1999-12-28 | 2006-04-04 | U & I Pharmaceuticals, Ltd. | Pharmaceutical compositions containing new polymorphic forms of olanzapine and uses thereof |
| DE60019461T2 (de) * | 1999-12-28 | 2005-09-22 | Cipla Ltd., Bombay | Neue polymorphe formen von olanzapin |
| PL196814B1 (pl) * | 2002-05-17 | 2008-02-29 | Inst Farmaceutyczny | Sposób wytwarzania odmiany polimorficznej I olanzapiny i jej solwaty |
| HU226410B1 (en) * | 2003-04-22 | 2008-11-28 | Egis Gyogyszergyar Nyilvanosan | Novel polymorphous forms of olanzapine hydrochlorides, process for producing them, use thereof and pharmaceutical compositions containing them |
| US6987111B2 (en) * | 2003-08-06 | 2006-01-17 | Alkermes Controlled Therapeutics, Ii | Aripiprazole, olanzapine and haloperidol pamoate salts |
| ES2289974T1 (es) * | 2004-07-14 | 2008-02-16 | Shasun Chemicals And Drugs Limited | Metodo mejorado para producir la forma i de la olanzapina. |
| ES2253091B1 (es) * | 2004-07-27 | 2007-02-01 | Inke, S.A. | Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo. |
| US20090155331A1 (en) * | 2005-11-16 | 2009-06-18 | Elan Pharma International Limited | Injectable nanoparticulate olanzapine formulations |
| CN101106972A (zh) * | 2004-11-16 | 2008-01-16 | 伊兰制药国际有限公司 | 注射用纳米微粒奥氮平制剂 |
| SI1838716T1 (sl) * | 2005-01-05 | 2011-10-28 | Lilly Co Eli | Olanzapin pamoat dihidrat |
| CZ2006697A3 (cs) * | 2006-11-07 | 2008-05-21 | Zentiva, A. S. | Kompozice depotních olanzapinových injekcních systému |
| FR2927965B1 (fr) * | 2008-02-22 | 2010-06-04 | Valeo Materiaux De Friction Sa | Procede de fabrication d'un materiau de friction et notamment d'une couronne de friction d'embrayage. |
| JP5486690B2 (ja) * | 2009-11-16 | 2014-05-07 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | メラノコルチン受容体リガンドの医薬組成物 |
| WO2011091142A2 (en) * | 2010-01-20 | 2011-07-28 | Teva Pharmaceutical Industries Ltd. | Crystalline and amorphous forms of olanzapine pamoate |
| EP2629775A4 (en) | 2010-10-18 | 2014-06-11 | Dainippon Sumitomo Pharma Co | INJECTABLE FORMULATION WITH DELAYED RELEASE |
| US9604995B2 (en) | 2013-02-13 | 2017-03-28 | Neuland Laboratories Limited | Process for the preparation of olanzapine pamoate |
| CN105044231B (zh) * | 2015-06-27 | 2022-09-13 | 万特制药(海南)有限公司 | 一种分离测定奥氮平双羟萘酸盐一水合物有关物质的方法 |
| WO2018172850A1 (en) * | 2017-03-20 | 2018-09-27 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulaitons |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2095499A1 (en) * | 1992-05-08 | 1993-11-09 | Petrus J. M. Van Den Oetelaar | Depot preparation |
| DE69327542T2 (de) * | 1992-11-17 | 2000-07-06 | Yoshitomi Pharmaceutical Industries, Ltd. | Ein antipsychotikum enthaltende mikrokugel zur verzögerten freisetzung und verfahren für ihre herstellung |
| TW376319B (en) * | 1993-04-28 | 1999-12-11 | Janssen Pharmaceutica Nv | Pharmaceutical composition containing risperidone pamoate and having a long acting activity for treating psychoses induced by the release of dopamine |
| EG23659A (en) * | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
| US5891461A (en) * | 1995-09-14 | 1999-04-06 | Cygnus, Inc. | Transdermal administration of olanzapine |
| JP2001500878A (ja) * | 1996-09-23 | 2001-01-23 | イーライ・リリー・アンド・カンパニー | オランザピン二水和物d |
| US6169084B1 (en) * | 1997-09-30 | 2001-01-02 | Eli Lilly And Company | 2-methyl-thieno-benzodiazepine formulation |
-
1999
- 1999-03-24 HK HK02100774.0A patent/HK1041199B/en not_active IP Right Cessation
- 1999-03-24 NZ NZ510208A patent/NZ510208A/xx not_active IP Right Cessation
- 1999-03-24 GE GEAP199911232A patent/GEP20094818B/en unknown
- 1999-03-24 UA UA2001032118A patent/UA66872C2/uk unknown
- 1999-03-24 DE DE69935873T patent/DE69935873T2/de not_active Expired - Lifetime
- 1999-03-24 AU AU33627/99A patent/AU759751B2/en not_active Expired
- 1999-03-24 CZ CZ20011149A patent/CZ302367B6/cs not_active IP Right Cessation
- 1999-03-24 DK DK99915009T patent/DK1119359T3/da active
- 1999-03-24 AT AT04005832T patent/ATE359793T1/de active
- 1999-03-24 HU HU0103636A patent/HU227400B1/hu unknown
- 1999-03-24 JP JP2000571926A patent/JP4551988B2/ja not_active Expired - Lifetime
- 1999-03-24 PT PT04005832T patent/PT1468689E/pt unknown
- 1999-03-24 HR HR20010238A patent/HRP20010238B1/xx not_active IP Right Cessation
- 1999-03-24 DE DE69917663T patent/DE69917663T2/de not_active Expired - Lifetime
- 1999-03-24 PT PT99915009T patent/PT1119359E/pt unknown
- 1999-03-24 EA EA200100406A patent/EA002580B1/ru not_active IP Right Cessation
- 1999-03-24 EP EP99915009A patent/EP1119359B1/en not_active Expired - Lifetime
- 1999-03-24 SK SK416-2001A patent/SK285944B6/sk not_active IP Right Cessation
- 1999-03-24 ID IDW20010679A patent/ID29574A/id unknown
- 1999-03-24 IL IL14176699A patent/IL141766A0/xx active IP Right Grant
- 1999-03-24 PL PL346981A patent/PL196821B1/pl unknown
- 1999-03-24 ES ES99915009T patent/ES2221376T3/es not_active Expired - Lifetime
- 1999-03-24 BR BR9914156-6A patent/BR9914156A/pt not_active Application Discontinuation
- 1999-03-24 WO PCT/US1999/006417 patent/WO2000018408A1/en not_active Ceased
- 1999-03-24 CN CNB998115355A patent/CN1146422C/zh not_active Expired - Lifetime
- 1999-03-24 ES ES04005832T patent/ES2285294T3/es not_active Expired - Lifetime
- 1999-03-24 TR TR2001/00885T patent/TR200100885T2/tr unknown
- 1999-03-24 CA CA002344873A patent/CA2344873A1/en not_active Withdrawn
- 1999-03-24 AT AT99915009T patent/ATE267602T1/de active
- 1999-03-24 DK DK04005832T patent/DK1468689T3/da active
- 1999-03-30 MY MYPI99001217A patent/MY126476A/en unknown
- 1999-04-02 TW TW088105028A patent/TW577890B/zh not_active IP Right Cessation
-
2001
- 2001-03-01 IL IL141766A patent/IL141766A/en not_active IP Right Cessation
- 2001-03-28 NO NO20011583A patent/NO328243B1/no not_active IP Right Cessation
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