TR200100672T2 - Yeni izoksazolinon antibakteriyel ajanları - Google Patents

Yeni izoksazolinon antibakteriyel ajanları

Info

Publication number
TR200100672T2
TR200100672T2 TR2001/00672T TR200100672T TR200100672T2 TR 200100672 T2 TR200100672 T2 TR 200100672T2 TR 2001/00672 T TR2001/00672 T TR 2001/00672T TR 200100672 T TR200100672 T TR 200100672T TR 200100672 T2 TR200100672 T2 TR 200100672T2
Authority
TR
Turkey
Prior art keywords
new
antibacterial agents
isoxazolinone
isoxazolinone antibacterial
present
Prior art date
Application number
TR2001/00672T
Other languages
English (en)
Inventor
B. Snyder Lawrence
Zheng Zhizhen
Original Assignee
Bristol-Myers Souibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Souibb Company filed Critical Bristol-Myers Souibb Company
Publication of TR200100672T2 publication Critical patent/TR200100672T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Mevcut bulus, antibakteriyel aktiviteye sahip ve bakteriyel hastaliklarin tedavisinde faydali olan izoksazolinon türevleri ile ilgilidir. Özellikle, bulus konusu yeni izoksazolinonlar asagidaki genel formüle (I) sahip olacak biçimde saglanmakta olup içerisindeki A ve R1 tarifnamede tanimlanmaktadir.
TR2001/00672T 1998-08-24 1999-08-23 Yeni izoksazolinon antibakteriyel ajanları TR200100672T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9757498P 1998-08-24 1998-08-24

Publications (1)

Publication Number Publication Date
TR200100672T2 true TR200100672T2 (tr) 2001-07-23

Family

ID=22264103

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/00672T TR200100672T2 (tr) 1998-08-24 1999-08-23 Yeni izoksazolinon antibakteriyel ajanları

Country Status (22)

Country Link
EP (1) EP1107756A4 (tr)
JP (1) JP2002523369A (tr)
KR (1) KR20010072945A (tr)
CN (1) CN1314813A (tr)
AR (1) AR020250A1 (tr)
AU (1) AU748750B2 (tr)
BR (1) BR9913225A (tr)
CA (1) CA2341271A1 (tr)
CO (1) CO5160266A1 (tr)
CZ (1) CZ2001669A3 (tr)
HU (1) HUP0103433A3 (tr)
ID (1) ID27690A (tr)
IL (1) IL141542A0 (tr)
NO (1) NO20010916L (tr)
NZ (1) NZ509867A (tr)
PE (1) PE20001063A1 (tr)
PL (1) PL346267A1 (tr)
TR (1) TR200100672T2 (tr)
TW (1) TW572757B (tr)
UY (1) UY25677A1 (tr)
WO (1) WO2000010566A1 (tr)
ZA (1) ZA200101505B (tr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2002020366A (ja) * 2000-07-05 2002-01-23 Sumitomo Seika Chem Co Ltd アルキルチオフェニル酢酸類の製造方法
PE20020689A1 (es) 2000-11-17 2002-08-03 Upjohn Co Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno
PE20030044A1 (es) 2000-11-17 2003-02-09 Upjohn Co Isoxazolinonas biciclicas de formula i
US6861433B2 (en) 2000-12-15 2005-03-01 Pharmacia & Upjohn Company Oxazolidinone photoaffinity probes
ATE319710T1 (de) 2000-12-21 2006-03-15 Pharmacia & Upjohn Co Llc Antimikrobielle chinolonderivate und ihre verwendung zur behandlung bakterieller infektionen
ES2180456B1 (es) * 2001-07-20 2004-05-01 Laboratorios S.A.L.V.A.T., S.A. Isoxazoles sustituidos y su utilizacion como antibioticos.
WO2003031443A1 (en) 2001-10-04 2003-04-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Dual actions antibiotics comprising a oxazoldinone and a quinolone or naphthyridinone moiety
JP2005512975A (ja) 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体
US6875784B2 (en) 2002-10-09 2005-04-05 Pharmacia & Upjohn Company Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives
MXPA05003774A (es) 2002-10-10 2005-06-08 Pharmacia & Upjohn Co Llc Compuestos de 1-aril-dihidropiridona con actividad antimicrobiana.
EP1594865A2 (en) * 2003-02-07 2005-11-16 Warner-Lambert Company LLC Antibacterial agents
ES2308171T3 (es) 2003-04-30 2008-12-01 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Uso de antibioticos hibridos de oxazolidinona-quinolina para el tratamiento del antrax y de otras infecciones.
AU2004267007C1 (en) 2003-06-03 2010-04-29 Melinta Subsidiary Corp. Biaryl heterocyclic compounds and methods of making and using the same
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
EP1646617A2 (en) * 2003-06-03 2006-04-19 Rib-X Pharmaceuticals, Inc. Sulfonamide compounds and methods of making and using the same
JP2007500707A (ja) * 2003-07-29 2007-01-18 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ビアリールヘテロ環状のアミン、アミドおよび硫黄−含有化合物、並びに該化合物の製造方法および使用方法
DE10340485B4 (de) 2003-09-03 2015-05-13 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
JP2007514782A (ja) 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
US8158797B2 (en) 2003-12-18 2012-04-17 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
CA2549675C (en) 2003-12-18 2012-11-20 Morphochem Aktiengesellschaft Fur Kombinatorische Chemie Oxazolidinone-quinolone hybrid antibiotics
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
US8399660B2 (en) 2005-06-08 2013-03-19 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
AT503354B1 (de) * 2006-02-22 2008-07-15 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von 3,4-disubstituierten phenylessigsäuren, sowie neue zwischenverbindungen
JP4518066B2 (ja) * 2006-10-25 2010-08-04 宇部興産株式会社 ジアルコキシニトリル誘導体及びその製法
CN110423610B (zh) * 2019-08-29 2023-05-12 浙江理工大学 一种检测双光子汞离子荧光探针及其制备方法与使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2045049A1 (de) * 1970-09-11 1972-03-23 Dr Karl Thomae GmbH, 7950 Biberach Neue Nitrofurandenvate und Ver fahren zu ihrer Herstellung
US4000155A (en) * 1975-12-11 1976-12-28 Eli Lilly And Company Herbicidal 2-methyl-4-phenyl-5-pyrazolinones[and isoxazolinones]
JP3558088B2 (ja) * 1992-12-08 2004-08-25 ファルマシア・アンド・アップジョン・カンパニー トロポン−置換のフェニルオキサゾリジノン抗菌剤
US5708169A (en) * 1995-09-15 1998-01-13 Pharmacia & Upjohn Company 5-amidomethyl α,β-saturated and -unsaturated 3-aryl butyrolactone antibacterial agents
GB9521508D0 (en) * 1995-10-20 1995-12-20 Zeneca Ltd Chemical compounds
US5990136A (en) * 1996-08-21 1999-11-23 Pharmacia & Upjohn Company Isoxazoline derivatives useful as antimicrobials

Also Published As

Publication number Publication date
EP1107756A1 (en) 2001-06-20
CZ2001669A3 (cs) 2001-08-15
AU5783399A (en) 2000-03-14
ID27690A (id) 2001-04-19
EP1107756A4 (en) 2003-02-26
IL141542A0 (en) 2002-03-10
NO20010916D0 (no) 2001-02-23
JP2002523369A (ja) 2002-07-30
HUP0103433A2 (hu) 2002-01-28
HUP0103433A3 (en) 2002-08-28
NZ509867A (en) 2003-08-29
AR020250A1 (es) 2002-05-02
PE20001063A1 (es) 2000-12-24
ZA200101505B (en) 2002-02-22
UY25677A1 (es) 2001-08-27
TW572757B (en) 2004-01-21
NO20010916L (no) 2001-04-10
WO2000010566A1 (en) 2000-03-02
CA2341271A1 (en) 2000-03-02
AU748750B2 (en) 2002-06-13
CN1314813A (zh) 2001-09-26
CO5160266A1 (es) 2002-05-30
BR9913225A (pt) 2001-05-22
PL346267A1 (en) 2002-01-28
KR20010072945A (ko) 2001-07-31

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