TR200101204T2 - Dialkil Fumaratlarının kullanımı - Google Patents
Dialkil Fumaratlarının kullanımıInfo
- Publication number
- TR200101204T2 TR200101204T2 TR2001/01204T TR200101204T TR200101204T2 TR 200101204 T2 TR200101204 T2 TR 200101204T2 TR 2001/01204 T TR2001/01204 T TR 2001/01204T TR 200101204 T TR200101204 T TR 200101204T TR 200101204 T2 TR200101204 T2 TR 200101204T2
- Authority
- TR
- Turkey
- Prior art keywords
- fumarates
- dialkil
- preparations
- micro
- transplantation medicine
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
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- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
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- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
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- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
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- A61K9/2095—Tabletting processes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
Abstract
Bulus,dialkil fumaratlarinin, transplantasyon hekimliginde veya bagisiklik sisteminde kendiliginden olusan hastaliklarin tedavisinde uygulanan tibbi ecza preparatlarinin ve dialkil fumaratlari içeren mikro tablet veya mikro haplar seklindeki tibbi ecza preparatlarinin imalatinda kullanilmasi ile ilgilidir. Dialkil fumaratlari bu amaçla transplantasyon hekimliginde alisilagelmis preparatlarla ve özellikle immünosüpresifler gibi siklosporinlerle kombinasyon halinde de kullanilabilmektedir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853487A DE19853487A1 (de) | 1998-11-19 | 1998-11-19 | Verwendung von Dialkylfumaraten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200101204T2 true TR200101204T2 (tr) | 2001-09-21 |
Family
ID=7888396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/01204T TR200101204T2 (tr) | 1998-11-19 | 1999-10-29 | Dialkil Fumaratlarının kullanımı |
Country Status (34)
| Country | Link |
|---|---|
| US (9) | US6509376B1 (tr) |
| EP (1) | EP1131065B1 (tr) |
| JP (7) | JP2002530324A (tr) |
| CN (2) | CN1615839A (tr) |
| AT (1) | ATE242633T1 (tr) |
| BE (1) | BE2014C040I2 (tr) |
| BG (1) | BG64837B1 (tr) |
| BR (1) | BR9914606A (tr) |
| CA (1) | CA2346438C (tr) |
| CY (1) | CY2014027I2 (tr) |
| CZ (1) | CZ299409B6 (tr) |
| DE (2) | DE19853487A1 (tr) |
| DK (1) | DK1131065T3 (tr) |
| EE (1) | EE04389B1 (tr) |
| ES (1) | ES2195664T3 (tr) |
| FR (1) | FR14C0051I2 (tr) |
| HK (1) | HK1042242B (tr) |
| HU (2) | HU226689B1 (tr) |
| IL (2) | IL142728A0 (tr) |
| LT (1) | LTC1131065I2 (tr) |
| LU (1) | LU92488I2 (tr) |
| ME (1) | ME00731B (tr) |
| MX (1) | MXPA01005007A (tr) |
| NO (3) | NO333257B1 (tr) |
| NZ (1) | NZ510247A (tr) |
| PL (2) | PL226074B1 (tr) |
| PT (1) | PT1131065E (tr) |
| RS (1) | RS49995B (tr) |
| RU (1) | RU2215524C2 (tr) |
| SI (1) | SI1131065T1 (tr) |
| SK (1) | SK285601B6 (tr) |
| TR (1) | TR200101204T2 (tr) |
| WO (1) | WO2000030622A2 (tr) |
| ZA (1) | ZA200202335B (tr) |
Families Citing this family (115)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19853487A1 (de) * | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
| DE10000577A1 (de) * | 2000-01-10 | 2001-07-26 | Fumapharm Ag Muri | Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten |
| US6912052B2 (en) * | 2000-11-17 | 2005-06-28 | Cymer, Inc. | Gas discharge MOPA laser spectral analysis module |
| DE10101307A1 (de) * | 2001-01-12 | 2002-08-01 | Fumapharm Ag Muri | Fumarsäurederivate als NF-kappaB-Inhibitor |
| AU2002219236B2 (en) * | 2001-01-12 | 2006-02-09 | Biogen International Gmbh | Fumaric acid amides |
| US20050259709A1 (en) * | 2002-05-07 | 2005-11-24 | Cymer, Inc. | Systems and methods for implementing an interaction between a laser shaped as a line beam and a film deposited on a substrate |
| DE10217314A1 (de) * | 2002-04-18 | 2003-11-13 | Fumapharm Ag Muri | Carbocyclische und Oxacarboncyclische Fumarsäure-Oligomere |
| WO2004112773A1 (en) * | 2003-04-24 | 2004-12-29 | Shin-Jen Shiao | Pharmaceutical compositions used for immune disease treatment and improvement |
| US7277188B2 (en) * | 2003-04-29 | 2007-10-02 | Cymer, Inc. | Systems and methods for implementing an interaction between a laser shaped as a line beam and a film deposited on a substrate |
| WO2005023241A1 (en) * | 2003-09-09 | 2005-03-17 | Fumapharm Ag | The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma |
| DE10360869A1 (de) * | 2003-09-09 | 2005-04-07 | Fumapharm Ag | Verwendung von Fumarsäurederivaten zur Therapie der Herzinsuffizienz, der Hyperkeratose und von Asthma |
| DE10342423A1 (de) * | 2003-09-13 | 2005-04-14 | Heidland, August, Prof. Dr.med. Dr.h.c. | Verwendung von Fumarsäurederivaten zur Prophylaxe und zur Behandlung von Genomschäden |
| US6873418B1 (en) | 2003-09-30 | 2005-03-29 | Cymer, Inc. | Optical mountings for gas discharge MOPA laser spectral analysis module |
| US6894785B2 (en) * | 2003-09-30 | 2005-05-17 | Cymer, Inc. | Gas discharge MOPA laser spectral analysis module |
| CA2478458A1 (en) * | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
| SI2801354T1 (sl) | 2004-10-08 | 2017-07-31 | Forward Pharma A/S | Farmacevtske sestave z nadzorovanim sproščanjem, ki zajemajo ester fumarne kisline |
| US20080004344A1 (en) * | 2004-11-10 | 2008-01-03 | Aditech Pharma Ab | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use |
| US7653095B2 (en) * | 2005-06-30 | 2010-01-26 | Cymer, Inc. | Active bandwidth control for a laser |
| WO2007006307A2 (en) * | 2005-07-07 | 2007-01-18 | Aditech Pharma Ab | Novel salts of fumaric acid monoalkylesters and their pharmaceutical use |
| US20100144651A1 (en) * | 2005-07-07 | 2010-06-10 | Aditech Pharma Ab | Novel glucopyranose esters and glucofuranose esters of alkyl- fumarates and their pharmaceutical use |
| US20080299196A1 (en) * | 2005-10-07 | 2008-12-04 | Aditech Pharma Ab | Controlled Release Pharmaceutical Compositions Comprising a Fumaric Acid Ester |
| WO2007042035A2 (en) * | 2005-10-07 | 2007-04-19 | Aditech Pharma Ab | Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders |
| US7679029B2 (en) * | 2005-10-28 | 2010-03-16 | Cymer, Inc. | Systems and methods to shape laser light as a line beam for interaction with a substrate having surface variations |
| US7317179B2 (en) * | 2005-10-28 | 2008-01-08 | Cymer, Inc. | Systems and methods to shape laser light as a homogeneous line beam for interaction with a film deposited on a substrate |
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1998
- 1998-11-19 DE DE19853487A patent/DE19853487A1/de not_active Withdrawn
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1999
- 1999-10-29 IL IL14272899A patent/IL142728A0/xx active IP Right Grant
- 1999-10-29 JP JP2000583505A patent/JP2002530324A/ja not_active Withdrawn
- 1999-10-29 DK DK99972532T patent/DK1131065T3/da active
- 1999-10-29 HK HK02103958.2A patent/HK1042242B/zh not_active IP Right Cessation
- 1999-10-29 PT PT99972532T patent/PT1131065E/pt unknown
- 1999-10-29 WO PCT/EP1999/008215 patent/WO2000030622A2/de not_active Ceased
- 1999-10-29 RU RU2001116566/14A patent/RU2215524C2/ru active
- 1999-10-29 CZ CZ20010939A patent/CZ299409B6/cs not_active IP Right Cessation
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- 1999-10-29 CN CNA200410011769XA patent/CN1615839A/zh active Pending
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- 1999-10-29 EP EP99972532A patent/EP1131065B1/de not_active Expired - Lifetime
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- 1999-10-29 CN CNB998123889A patent/CN1182844C/zh not_active Expired - Lifetime
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- 1999-10-29 SK SK576-2001A patent/SK285601B6/sk not_active IP Right Cessation
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- 1999-10-29 EE EEP200100266A patent/EE04389B1/xx active Protection Beyond IP Right Term
- 1999-10-29 AT AT99972532T patent/ATE242633T1/de active
- 1999-10-29 BR BR9914606-1A patent/BR9914606A/pt not_active Application Discontinuation
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2001
- 2001-03-12 NO NO20011242A patent/NO333257B1/no not_active IP Right Cessation
- 2001-03-30 BG BG105396A patent/BG64837B1/bg unknown
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2002
- 2002-03-22 ZA ZA200202335A patent/ZA200202335B/en unknown
- 2002-07-17 US US10/197,077 patent/US7320999B2/en not_active Expired - Lifetime
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2004
- 2004-12-21 JP JP2004368948A patent/JP2005097323A/ja active Pending
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2007
- 2007-06-20 US US11/765,563 patent/US7612110B2/en not_active Expired - Fee Related
- 2007-06-20 US US11/765,578 patent/US7619001B2/en not_active Expired - Fee Related
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2009
- 2009-03-17 US US12/405,665 patent/US7915310B2/en not_active Expired - Lifetime
- 2009-03-17 US US12/405,661 patent/US7803840B2/en not_active Expired - Fee Related
- 2009-08-10 JP JP2009185402A patent/JP5828614B2/ja not_active Expired - Lifetime
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2011
- 2011-03-04 US US13/040,914 patent/US8759393B2/en not_active Expired - Fee Related
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2012
- 2012-08-24 JP JP2012185136A patent/JP2012255020A/ja not_active Withdrawn
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2013
- 2013-03-13 US US13/800,128 patent/US20140066505A1/en not_active Abandoned
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2014
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2015
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2019
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