TR200201880T2 - PDE4 izozimerlerinin seçici önleyicileri olarak faydalı nikotinamit benzobağlı-heterosiklil türevleri - Google Patents

PDE4 izozimerlerinin seçici önleyicileri olarak faydalı nikotinamit benzobağlı-heterosiklil türevleri

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Publication number
TR200201880T2
TR200201880T2 TR2002/01880T TR200201880T TR200201880T2 TR 200201880 T2 TR200201880 T2 TR 200201880T2 TR 2002/01880 T TR2002/01880 T TR 2002/01880T TR 200201880 T TR200201880 T TR 200201880T TR 200201880 T2 TR200201880 T2 TR 200201880T2
Authority
TR
Turkey
Prior art keywords
formula
selective inhibitors
derivatives useful
pde4 isozymes
heterocyclyl derivatives
Prior art date
Application number
TR2002/01880T
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English (en)
Inventor
Marfat Anthony
James Chamber Robert
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200201880T2 publication Critical patent/TR200201880T2/tr

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Abstract

Eozinofillerin aktivasyonu ve degranülasyonu ile düzenlenen hastaliklarin, özellikle de astim, kronik bronsit ve kronik engelleyici akciger hastaliginin tedavisinde PDE4 önleyicileri olarak faydali Formül (1.0.0)'a ait bilesikler. Adi geçen formülde R5 ve R6, (1.1.1) ila (1.1.5) arasindaki kismi Formüllere ait bir yarim veya bunun farmasötik açidan kabul gören bir tuzunu olusturmak üzere birlikte alinir. Formül (1.0.0) Formül (1.1.1) Formül (1.1.2) Formül (1.1.3) Formül (1.1.4) Formül (1.1.5)
TR2002/01880T 2000-01-31 2001-01-30 PDE4 izozimerlerinin seçici önleyicileri olarak faydalı nikotinamit benzobağlı-heterosiklil türevleri TR200201880T2 (tr)

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US17928400P 2000-01-31 2000-01-31

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TR200201880T2 true TR200201880T2 (tr) 2002-11-21

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TR2002/01880T TR200201880T2 (tr) 2000-01-31 2001-01-30 PDE4 izozimerlerinin seçici önleyicileri olarak faydalı nikotinamit benzobağlı-heterosiklil türevleri

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WO2001057036A1 (en) 2001-08-09
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PT1252158E (pt) 2005-09-30
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