TR200400357T4 - Pravastatin üretimi için bir işlem - Google Patents

Pravastatin üretimi için bir işlem

Info

Publication number
TR200400357T4
TR200400357T4 TR2004/00357T TR200400357T TR200400357T4 TR 200400357 T4 TR200400357 T4 TR 200400357T4 TR 2004/00357 T TR2004/00357 T TR 2004/00357T TR 200400357 T TR200400357 T TR 200400357T TR 200400357 T4 TR200400357 T4 TR 200400357T4
Authority
TR
Turkey
Prior art keywords
pravastatin
production
aspergillus
exocellular
fermentation
Prior art date
Application number
TR2004/00357T
Other languages
English (en)
Inventor
Benedetti Alberto
Manzoni Matilde
Nichele Marina
Rollini Manuela
Original Assignee
Gnosis Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Srl filed Critical Gnosis Srl
Publication of TR200400357T4 publication Critical patent/TR200400357T4/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pyrane Compounds (AREA)

Abstract

Bulus, pravastatin üretimi için bir isleme iliskindir. Özel olarak, bulus, Monarcus türünden mikroorganizmalarin yerlestirilmesiyle, hücre disi pravastatinin dogrudan bir mayalama ortaminda üretilmesi için bir mayalama islemine iliskindir.
TR2004/00357T 2001-06-15 2001-06-15 Pravastatin üretimi için bir işlem TR200400357T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01114462A EP1266967B1 (en) 2001-06-15 2001-06-15 Process for the production of pravastatin and lovastatin

Publications (1)

Publication Number Publication Date
TR200400357T4 true TR200400357T4 (tr) 2004-03-22

Family

ID=8177727

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/00357T TR200400357T4 (tr) 2001-06-15 2001-06-15 Pravastatin üretimi için bir işlem

Country Status (7)

Country Link
EP (1) EP1266967B1 (tr)
AT (1) ATE258603T1 (tr)
DE (1) DE60101904T2 (tr)
DK (1) DK1266967T3 (tr)
ES (1) ES2210066T3 (tr)
PT (1) PT1266967E (tr)
TR (1) TR200400357T4 (tr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100048938A1 (en) * 2006-06-22 2010-02-25 Marco Alexander Van Den Berg Fermentation of pravastatin
WO2009077523A2 (en) * 2007-12-18 2009-06-25 Dsm Ip Assets B.V. Improved statin production
JP6916482B2 (ja) * 2016-06-23 2021-08-11 学校法人日本大学 アスペルギルス・テレウス検出用プローブ、及びアスペルギルス・テレウスの検出方法
CN112553262B (zh) * 2020-12-31 2023-04-07 广东蓝宝制药有限公司 一种普伐他汀的发酵工艺
CN113061536B (zh) * 2021-03-17 2022-08-23 江南大学 一株高产洛伐他汀的紫色红曲菌z-27及其应用
CN114958625B (zh) * 2022-07-07 2023-12-19 福安药业集团烟台只楚药业有限公司 一种发酵生产洛伐他汀的土曲霉的培养与保存方法
CN116925926B (zh) * 2023-07-14 2024-02-02 中国农业大学 富硒红色红曲霉发酵生产洛伐他汀的方法

Also Published As

Publication number Publication date
DE60101904D1 (de) 2004-03-04
ATE258603T1 (de) 2004-02-15
DK1266967T3 (da) 2004-05-03
EP1266967B1 (en) 2004-01-28
ES2210066T3 (es) 2004-07-01
PT1266967E (pt) 2004-05-31
DE60101904T2 (de) 2004-07-15
EP1266967A1 (en) 2002-12-18

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