TR200700067T2 - Corynebacterium glutamicum gen kodlayıcı fosfoenol piruvat : şeker fosfotransferaz sistem proteini - Google Patents
Corynebacterium glutamicum gen kodlayıcı fosfoenol piruvat : şeker fosfotransferaz sistem proteiniInfo
- Publication number
- TR200700067T2 TR200700067T2 TR2007/00067T TR200700067T TR200700067T2 TR 200700067 T2 TR200700067 T2 TR 200700067T2 TR 2007/00067 T TR2007/00067 T TR 2007/00067T TR 200700067 T TR200700067 T TR 200700067T TR 200700067 T2 TR200700067 T2 TR 200700067T2
- Authority
- TR
- Turkey
- Prior art keywords
- pts
- nucleic acid
- acid molecules
- corynebacterium glutamicum
- gene coding
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 241000186226 Corynebacterium glutamicum Species 0.000 title abstract 3
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 229930029653 phosphoenolpyruvate Natural products 0.000 title 1
- DTBNBXWJWCWCIK-UHFFFAOYSA-N phosphoenolpyruvic acid Chemical compound OC(=O)C(=C)OP(O)(O)=O DTBNBXWJWCWCIK-UHFFFAOYSA-N 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 abstract 4
- 108020004707 nucleic acids Proteins 0.000 abstract 4
- 150000007523 nucleic acids Chemical class 0.000 abstract 4
- 239000013604 expression vector Substances 0.000 abstract 2
- 230000000692 anti-sense effect Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 238000010353 genetic engineering Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1223—Phosphotransferases with a nitrogenous group as acceptor (2.7.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/03—Phosphotransferases with a nitrogenous group as acceptor (2.7.3)
- C12Y207/03009—Phosphoenolpyruvate-protein phosphotransferase (2.7.3.9)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Corynebacterium glutamicum'dan türetilmiş yeni PTS proteinlerini şifreleyen PTS nükleik asit molekülleri adlı izole edilmiş nükleik asit molekülleri tarif edilmektedir. Buluş anti duyarlı nükleik asit molekülleri, PTS nükleik asit molekülleri ihtiva eden yeniden birleştirici tanım vektörleri ve tanım vektörlerinin yerleştirildiği konakçı hücreler de sağlar. Hali hazırda buluş ayrıca izole edilmiş PTS proteinleri, mutasyon geçirmiş PTS proteinleri, füzyon proteinleri, antijenik peptitler ve bu organizmadaki PTS genlerinin genetik mühendisliğine dayanarak arzu edilen bir bileşiğin C. Glutamicum'dan üretiminin geliştirilmesine yönelik metotlar sağlar.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14269199P | 1999-07-01 | 1999-07-01 | |
| US15031099P | 1999-08-23 | 1999-08-23 | |
| DE19942097 | 1999-09-03 | ||
| DE19942095 | 1999-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200700067T2 true TR200700067T2 (tr) | 2007-03-21 |
Family
ID=27438980
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/03854T TR200103854T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium glutamicum gen kodlayıcı fosfonolpiruvat: şeker fosfotransferaz sistem proteini |
| TR2007/00067T TR200700067T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium glutamicum gen kodlayıcı fosfoenol piruvat : şeker fosfotransferaz sistem proteini |
| TR2007/00068T TR200700068T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium Glutamicum gen kodlayıcı fosfoenol piruvat: şeker fosfotransferaz sistem proteini |
| TR2004/03465T TR200403465T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium glutamicum gen kodlayıcı fosfonolpiruvat:seker fosfotransferaz sistem proteini |
| TR2007/00069T TR200700069T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium glutamicum gen kodlayıcı fosfoenol piruvat: şeker fosfotransferaz sistem proteini. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/03854T TR200103854T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium glutamicum gen kodlayıcı fosfonolpiruvat: şeker fosfotransferaz sistem proteini |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2007/00068T TR200700068T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium Glutamicum gen kodlayıcı fosfoenol piruvat: şeker fosfotransferaz sistem proteini |
| TR2004/03465T TR200403465T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium glutamicum gen kodlayıcı fosfonolpiruvat:seker fosfotransferaz sistem proteini |
| TR2007/00069T TR200700069T2 (tr) | 1999-07-01 | 2000-06-27 | Corynebacterium glutamicum gen kodlayıcı fosfoenol piruvat: şeker fosfotransferaz sistem proteini. |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP1246922B1 (tr) |
| JP (3) | JP2003512024A (tr) |
| KR (2) | KR20020025099A (tr) |
| CN (2) | CN1371420A (tr) |
| AU (1) | AU783697B2 (tr) |
| BR (1) | BR0012038A (tr) |
| CA (1) | CA2377378A1 (tr) |
| CZ (1) | CZ20014700A3 (tr) |
| ES (1) | ES2174768T1 (tr) |
| HU (1) | HUP0203191A3 (tr) |
| MX (1) | MXPA01012932A (tr) |
| PL (1) | PL359501A1 (tr) |
| SK (1) | SK18892001A3 (tr) |
| TR (5) | TR200103854T2 (tr) |
| WO (1) | WO2001002583A2 (tr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU781091B2 (en) * | 1999-07-02 | 2005-05-05 | Ajinomoto Co., Inc. | DNA encoding sucrose PTS enzyme II |
| DE10001101A1 (de) * | 2000-01-13 | 2001-07-19 | Degussa | Neue für das ptsH-Gen codierende Nukleotidsequenzen |
| US6818432B2 (en) | 2000-01-13 | 2004-11-16 | Degussa Ag | Nucleotide sequences encoding the ptsH gene |
| DE10045496A1 (de) | 2000-09-14 | 2002-03-28 | Degussa | Neue für das ptsi-Gen kodierende Nukleotidsequenzen |
| DE10154276A1 (de) * | 2001-11-05 | 2003-05-15 | Basf Ag | Gene die für Phosphoenolpyruvat-Zucker-phosphotransferase Proteine codieren |
| US7468262B2 (en) | 2003-05-16 | 2008-12-23 | Ajinomoto Co., Inc. | Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum |
| DE602005020165D1 (de) * | 2004-09-28 | 2010-05-06 | Kyowa Hakko Bio Co Ltd | Verfahren zur herstellung von l-arginin, l-ornithin oder l-citrullin |
| EP1929028A1 (en) * | 2005-09-27 | 2008-06-11 | Ajinomoto Co., Inc. | An l-amino acid-producing bacterium and a method for producing l-amino acids |
| US8048649B2 (en) * | 2007-09-26 | 2011-11-01 | Archer Daniels Midland Company | Production of amino acids from sucrose in Corynebacterium glutamicum |
| JP5564423B2 (ja) * | 2008-06-17 | 2014-07-30 | 公益財団法人地球環境産業技術研究機構 | D−キシロース利用機能が向上したコリネ型細菌形質転換体 |
| JP5663859B2 (ja) * | 2009-11-13 | 2015-02-04 | 三菱化学株式会社 | 非アミノ有機酸生産菌および非アミノ有機酸の製造方法 |
| EP3431599B1 (en) * | 2016-03-16 | 2022-06-15 | Kumiai Chemical Industry Co., Ltd. | A tentoxin synthesis gene, a method for producing tentoxin or dihydrotentoxin using the same, and a transformant comprising the same |
| BR112019008320A2 (pt) * | 2016-10-24 | 2020-01-28 | Evonik Degussa Gmbh | células e método para produzir ramnolipídios com o uso de transportadores de glicose alternativos |
| US10767205B2 (en) | 2017-03-07 | 2020-09-08 | DePuy Synthes Products, Inc. | Bacterium for the production of an exopolysaccharide comprising N-acetylglucosamine and D-glucose |
| US10633682B2 (en) | 2017-03-07 | 2020-04-28 | DePuy Synthes Products, Inc. | Bioresorbable exopolysaccharides |
| CN112062821B (zh) * | 2020-09-24 | 2022-02-01 | 江南大学 | 一种碳分解代谢调控蛋白CcpA突变体K31A |
| CN114763372B (zh) * | 2021-01-13 | 2024-12-10 | 中国科学院天津工业生物技术研究所 | 具有l-脯氨酸外排功能的蛋白及其应用 |
| KR20240108883A (ko) * | 2022-12-30 | 2024-07-10 | 씨제이제일제당 (주) | 신규한 폴리뉴클레오티드 및 이를 이용한 l-알라닌 생산 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
| US4649119A (en) | 1983-04-28 | 1987-03-10 | Massachusetts Institute Of Technology | Cloning systems for corynebacterium |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| GB2223754B (en) * | 1988-09-12 | 1992-07-22 | Degussa | Dna encoding phosphoenolpyruvate carboxylase |
| DE4120867A1 (de) | 1991-06-25 | 1993-01-07 | Agfa Gevaert Ag | Fotografisches verarbeitungsverfahren und vorrichtung dafuer |
| EP0693558B1 (en) | 1994-07-19 | 2002-12-04 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Trehalose and its production and use |
| JP4469026B2 (ja) * | 1996-10-31 | 2010-05-26 | ヒューマン ジノーム サイエンシーズ,インコーポレイテッド | Streptococcus pneumoniaeの抗原およびワクチン |
| DE19823834A1 (de) | 1998-05-28 | 1999-12-02 | Basf Ag | Genetisches Verfahren zur Herstellung von Riboflavin |
| AU781091B2 (en) * | 1999-07-02 | 2005-05-05 | Ajinomoto Co., Inc. | DNA encoding sucrose PTS enzyme II |
| JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
-
2000
- 2000-06-27 MX MXPA01012932A patent/MXPA01012932A/es not_active Application Discontinuation
- 2000-06-27 WO PCT/IB2000/000973 patent/WO2001002583A2/en not_active Ceased
- 2000-06-27 TR TR2001/03854T patent/TR200103854T2/tr unknown
- 2000-06-27 EP EP00942322A patent/EP1246922B1/en not_active Expired - Lifetime
- 2000-06-27 KR KR1020017016970A patent/KR20020025099A/ko not_active Withdrawn
- 2000-06-27 CN CN00812165A patent/CN1371420A/zh active Pending
- 2000-06-27 HU HU0203191A patent/HUP0203191A3/hu unknown
- 2000-06-27 KR KR1020067022021A patent/KR20060121993A/ko not_active Withdrawn
- 2000-06-27 PL PL00359501A patent/PL359501A1/xx unknown
- 2000-06-27 TR TR2007/00067T patent/TR200700067T2/tr unknown
- 2000-06-27 CN CNA2005100672071A patent/CN1680559A/zh active Pending
- 2000-06-27 TR TR2007/00068T patent/TR200700068T2/tr unknown
- 2000-06-27 JP JP2001508355A patent/JP2003512024A/ja active Pending
- 2000-06-27 TR TR2004/03465T patent/TR200403465T2/tr unknown
- 2000-06-27 BR BR0012038-3A patent/BR0012038A/pt not_active IP Right Cessation
- 2000-06-27 TR TR2007/00069T patent/TR200700069T2/tr unknown
- 2000-06-27 AU AU57014/00A patent/AU783697B2/en not_active Ceased
- 2000-06-27 CA CA002377378A patent/CA2377378A1/en not_active Abandoned
- 2000-06-27 CZ CZ20014700A patent/CZ20014700A3/cs unknown
- 2000-06-27 SK SK1889-2001A patent/SK18892001A3/sk not_active Application Discontinuation
- 2000-06-27 ES ES00942322T patent/ES2174768T1/es active Pending
- 2000-06-27 EP EP10012211.8A patent/EP2272953B1/en not_active Expired - Lifetime
-
2007
- 2007-04-25 JP JP2007115460A patent/JP2007267744A/ja not_active Withdrawn
- 2007-04-25 JP JP2007115387A patent/JP2007236393A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001002583A2 (en) | 2001-01-11 |
| KR20020025099A (ko) | 2002-04-03 |
| TR200700069T2 (tr) | 2007-02-21 |
| PL359501A1 (en) | 2004-08-23 |
| JP2007267744A (ja) | 2007-10-18 |
| EP1246922A2 (en) | 2002-10-09 |
| ES2174768T1 (es) | 2002-11-16 |
| CA2377378A1 (en) | 2001-01-11 |
| TR200103854T2 (tr) | 2002-06-21 |
| TR200700068T2 (tr) | 2007-03-21 |
| WO2001002583A3 (en) | 2001-07-26 |
| HUP0203191A3 (en) | 2009-01-28 |
| EP2272953A1 (en) | 2011-01-12 |
| EP1246922B1 (en) | 2010-10-13 |
| AU5701400A (en) | 2001-01-22 |
| MXPA01012932A (es) | 2002-07-30 |
| CN1680559A (zh) | 2005-10-12 |
| CZ20014700A3 (cs) | 2002-06-12 |
| CN1371420A (zh) | 2002-09-25 |
| SK18892001A3 (sk) | 2002-09-10 |
| HUP0203191A2 (hu) | 2002-12-28 |
| JP2003512024A (ja) | 2003-04-02 |
| AU783697B2 (en) | 2005-11-24 |
| EP2272953B1 (en) | 2014-09-24 |
| KR20060121993A (ko) | 2006-11-29 |
| BR0012038A (pt) | 2002-07-02 |
| JP2007236393A (ja) | 2007-09-20 |
| TR200403465T2 (tr) | 2005-03-21 |
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