TWI419681B - 胺基甲酸酯用於製造供治療白天過度嗜睡（eds）的藥物之用途 - Google Patents

胺基甲酸酯用於製造供治療白天過度嗜睡（eds）的藥物之用途 Download PDF

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Publication number
TWI419681B
TWI419681B TW095120134A TW95120134A TWI419681B TW I419681 B TWI419681 B TW I419681B TW 095120134 A TW095120134 A TW 095120134A TW 95120134 A TW95120134 A TW 95120134A TW I419681 B TWI419681 B TW I419681B
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Taiwan
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sleep
mirror image
formula
compound
eds
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TW095120134A
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English (en)
Chinese (zh)
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TW200716084A (en
Inventor
艾達 安
卓威翰
白喬瑟
施強生
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Ｓｋ生物製藥股份有限公司
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Application filed by Ｓｋ生物製藥股份有限公司 filed Critical Ｓｋ生物製藥股份有限公司
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW095120134A 2005-06-08 2006-06-07 胺基甲酸酯用於製造供治療白天過度嗜睡（eds）的藥物之用途 TWI419681B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68863805P 2005-06-08 2005-06-08

Publications (2)

Publication Number Publication Date
TW200716084A TW200716084A (en) 2007-05-01
TWI419681B true TWI419681B (zh) 2013-12-21

Family

ID=37085728

Family Applications (2)

Application Number Title Priority Date Filing Date
TW095120134A TWI419681B (zh) 2005-06-08 2006-06-07 胺基甲酸酯用於製造供治療白天過度嗜睡（eds）的藥物之用途
TW101130937A TW201328689A (zh) 2005-06-08 2006-06-07 治療睡眠-覺醒病症之方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW101130937A TW201328689A (zh) 2005-06-08 2006-06-07 治療睡眠-覺醒病症之方法

Country Status (17)

Country Link
US (8) US8440715B2 (2)
EP (1) EP1890684B1 (2)
JP (1) JP5024635B2 (2)
KR (1) KR101335941B1 (2)
CN (1) CN101217949B (2)
AU (1) AU2006254899B2 (2)
BE (1) BE2020C004I2 (2)
BR (1) BRPI0613697A2 (2)
CA (1) CA2611713C (2)
DK (1) DK1890684T3 (2)
ES (1) ES2435403T3 (2)
FR (1) FR20C1014I2 (2)
NL (1) NL301037I2 (2)
PL (1) PL1890684T3 (2)
RU (1) RU2417077C2 (2)
TW (2) TWI419681B (2)
WO (1) WO2006133393A1 (2)

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ES2344469T3 (es) * 2005-06-22 2010-08-27 Sk Holdings Co., Ltd. Tratamiento de disfuncion sexual.
KR102173587B1 (ko) * 2009-06-22 2020-11-04 에스케이바이오팜 주식회사 피로의 치료 또는 예방 방법
US8232315B2 (en) * 2009-06-26 2012-07-31 Sk Biopharmaceuticals Co., Ltd. Methods for treating drug addiction and improving addiction-related behavior
US8895609B2 (en) * 2009-11-06 2014-11-25 Sk Biopharmaceuticals Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
MX350745B (es) * 2009-11-06 2017-09-14 Sk Biopharmaceuticals Co Ltd * El uso de un compuesto de carbamoilo para el tratamiento del sindrome de fibromialgia.
US8623913B2 (en) * 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) * 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US9359290B2 (en) * 2013-03-13 2016-06-07 Jazz Pharmaceuticals International Iii Limited Treatment of cataplexy
KR102309836B1 (ko) 2013-07-18 2021-10-12 에스케이바이오팜 주식회사 비만의 치료
TWI698415B (zh) * 2014-02-28 2020-07-11 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10888542B2 (en) 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
WO2016061488A1 (en) 2014-10-17 2016-04-21 Concert Pharmaceuticals, Inc. Amine reuptake inhibitors
JP6466792B2 (ja) * 2015-07-03 2019-02-06 エスケー バイオファーマスティカルズ カンパニー リミテッド 注意欠陥／多動性障害（ａｄｈｄ）の治療方法
TWI637765B (zh) * 2016-05-10 2018-10-11 台灣共振波研發股份有限公司 Soothing device for attention deficit hyperactivity disorder
ES2970887T3 (es) 2016-09-06 2024-05-31 Axsome Malta Ltd Forma de solvato de carbamato de (R)-2-amino-3-fenilpropilo
US10195151B2 (en) * 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
EP4316592A3 (en) 2016-10-06 2024-05-01 Axsome Malta Ltd. Carbamoyl phenylalaninol compounds and uses thereof
AU2018278332B2 (en) 2017-06-02 2022-05-19 Jazz Pharmaceuticals Ireland Limited Methods and compositions for treating excessive sleepiness
KR102643275B1 (ko) * 2017-07-31 2024-03-04 재즈 파마슈티칼즈 아일랜드 리미티드 카바모일 페닐알라니놀 유사체 및 이의 용도
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
US11033214B1 (en) * 2020-05-19 2021-06-15 United Arab Emirates University Wearable eye tracking system
KR102390194B1 (ko) 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물
AU2023375326A1 (en) * 2022-11-07 2025-05-22 Axsome Therapeutics Compositions and methods for treating insomnia
WO2024118904A1 (en) * 2022-11-30 2024-06-06 Axsome Therapeutics Methods and compositions for improving driving performance
KR20260033050A (ko) 2023-06-29 2026-03-10 액섬 테라퓨틱스, 인크. 수유 여성에게 솔리암페톨을 투여하는 방법
WO2025165760A1 (en) * 2024-01-29 2025-08-07 Axsome Therapeutics, Inc. Phenylalkylamino carbamates for use in the treatment of attention deficit/hyperactivity disorder

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US8232315B2 (en) 2009-06-26 2012-07-31 Sk Biopharmaceuticals Co., Ltd. Methods for treating drug addiction and improving addiction-related behavior
MX350745B (es) 2009-11-06 2017-09-14 Sk Biopharmaceuticals Co Ltd * El uso de un compuesto de carbamoilo para el tratamiento del sindrome de fibromialgia.
US8895609B2 (en) 2009-11-06 2014-11-25 Sk Biopharmaceuticals Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
US8623913B2 (en) 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
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US5955499A (en) * 1994-09-09 1999-09-21 Yukong Limited Phenylalkylaminoalcohol carbamates and process for preparing the same
US5756817A (en) * 1995-02-11 1998-05-26 Yukong Limited O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same
US5756817C1 (en) * 1995-02-11 2001-04-17 Sk Corp O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same

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Also Published As

Publication number Publication date
TW200716084A (en) 2007-05-01
JP5024635B2 (ja) 2012-09-12
WO2006133393A1 (en) 2006-12-14
AU2006254899B2 (en) 2011-11-24
US12209059B2 (en) 2025-01-28
FR20C1014I1 (2) 2020-06-12
US20170158622A1 (en) 2017-06-08
CN101217949A (zh) 2008-07-09
US8877806B2 (en) 2014-11-04
US20190367448A1 (en) 2019-12-05
CN101217949B (zh) 2012-10-17
RU2417077C2 (ru) 2011-04-27
US8440715B2 (en) 2013-05-14
US11753368B2 (en) 2023-09-12
US20090312416A1 (en) 2009-12-17
EP1890684B1 (en) 2013-08-14
NL301037I1 (2) 2020-04-01
KR101335941B1 (ko) 2013-12-04
US20210078943A1 (en) 2021-03-18
BE2020C004I2 (2) 2026-01-06
RU2008100019A (ru) 2009-07-20
AU2006254899A1 (en) 2006-12-14
BRPI0613697A2 (pt) 2011-01-25
US9604917B2 (en) 2017-03-28
CA2611713C (en) 2013-10-01
EP1890684A1 (en) 2008-02-27
ES2435403T3 (es) 2013-12-19
CA2611713A1 (en) 2006-12-14
US10351517B2 (en) 2019-07-16
KR20080035565A (ko) 2008-04-23
PL1890684T3 (pl) 2014-05-30
TW201328689A (zh) 2013-07-16
US20130137764A1 (en) 2013-05-30
US20240239740A1 (en) 2024-07-18
NL301037I2 (nl) 2020-05-12
US20250109099A1 (en) 2025-04-03
DK1890684T3 (da) 2013-10-14
JP2008545795A (ja) 2008-12-18
US20140350098A1 (en) 2014-11-27
FR20C1014I2 (fr) 2021-04-23

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