UA27901C2 - Похідні 7-(2-аміноетил)бензотіазолону, що проявляють агоністичну активність по відношенню до бета2-адренорецепторів, фармацевтична композиція, спосіб їх отримання та проміжні сполуки - Google Patents

Похідні 7-(2-аміноетил)бензотіазолону, що проявляють агоністичну активність по відношенню до бета2-адренорецепторів, фармацевтична композиція, спосіб їх отримання та проміжні сполуки

Info

Publication number: UA27901C2
Authority: UA; Ukraine
Prior art keywords: aminoethyl; derivatives; pharmacatsyaphyat; benzotiazolone; adrenoreceptors
Prior art date: 1992-05-27

Application number

UA94119105A

Other languages

English (en)

Russian (ru)

Inventor

Роджер Віктор Боннет

Роджер Чарльз Браун

Дейвід Рейнулф Чешир

Френсіс Інсе

Original Assignee

Астра Фармасьютикалз Лімітид

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-27

Filing date

1993-05-27

Publication date

2000-10-16

1993-05-27 Application filed by Астра Фармасьютикалз Лімітид filed Critical Астра Фармасьютикалз Лімітид

2000-10-16 Publication of UA27901C2 publication Critical patent/UA27901C2/uk

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Ophthalmology & Optometry (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Cosmetics (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Adhesives Or Adhesive Processes (AREA)

UA94119105A 1992-05-27 1993-05-27 Похідні 7-(2-аміноетил)бензотіазолону, що проявляють агоністичну активність по відношенню до бета2-адренорецепторів, фармацевтична композиція, спосіб їх отримання та проміжні сполуки UA27901C2 (uk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929211172A GB9211172D0 (en)	1992-05-27	1992-05-27	Compounds
PCT/GB1993/001095 WO1993024473A1 (en)	1992-05-27	1993-05-27	7-(2-aminoethyl)-benzothiazolones

Publications (1)

Publication Number	Publication Date
UA27901C2 true UA27901C2 (uk)	2000-10-16

Family

ID=10716059

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA94119105A UA27901C2 (uk)	1992-05-27	1993-05-27	Похідні 7-(2-аміноетил)бензотіазолону, що проявляють агоністичну активність по відношенню до бета2-адренорецепторів, фармацевтична композиція, спосіб їх отримання та проміжні сполуки

Country Status (31)

Country	Link
EP (1)	EP0649418B1 (uk)
JP (1)	JP3094452B2 (uk)
KR (1)	KR100279132B1 (uk)
CN (1)	CN1036393C (uk)
AT (1)	ATE172726T1 (uk)
AU (1)	AU675649B2 (uk)
CA (1)	CA2136553C (uk)
CZ (1)	CZ286905B6 (uk)
DE (1)	DE69321835T2 (uk)
DK (1)	DK0649418T3 (uk)
DZ (1)	DZ1694A1 (uk)
ES (1)	ES2123652T3 (uk)
FI (1)	FI945538A0 (uk)
GB (1)	GB9211172D0 (uk)
HU (2)	HUT71124A (uk)
IL (1)	IL105801A (uk)
LV (1)	LV12443B (uk)
MA (1)	MA22895A1 (uk)
MX (1)	MX9303145A (uk)
MY (1)	MY131193A (uk)
NO (1)	NO304739B1 (uk)
NZ (1)	NZ253190A (uk)
PH (1)	PH31453A (uk)
PL (2)	PL172807B1 (uk)
RU (1)	RU2114108C1 (uk)
SG (1)	SG48068A1 (uk)
SK (1)	SK281282B6 (uk)
TW (1)	TW368501B (uk)
UA (1)	UA27901C2 (uk)
WO (1)	WO1993024473A1 (uk)
ZA (1)	ZA933648B (uk)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW356468B (en) *	1995-09-15	1999-04-21	Astra Pharma Prod	Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) *	1995-12-23	1996-02-28	Astra Pharma Prod	Pharmaceutically active compounds
SE9900693D0 (sv) *	1999-02-26	1999-02-26	Astra Pharma Prod	Novel process
SE9902938D0 (sv) *	1999-08-18	1999-08-18	Astra Pharma Prod	Pharmaceutical compositions
SE9902937D0 (sv) *	1999-08-18	1999-08-18	Astra Pharma Prod	Pharmaceutical compositions
SE9902935D0 (sv) *	1999-08-18	1999-08-18	Astra Pharma Prod	Pharmaceutical compositions
SE9902936D0 (sv) *	1999-08-18	1999-08-18	Astra Pharma Prod	Pharmaceutical compositions
DE10063957A1 (de) *	2000-12-20	2002-06-27	Boehringer Ingelheim Pharma	Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Dopamin-Agonisten
GB0218629D0 (en) *	2002-08-09	2002-09-18	Novartis Ag	Organic compounds
PE20050130A1 (es) *	2002-08-09	2005-03-29	Novartis Ag	Compuestos organicos
ES2329586T3 (es)	2003-11-21	2009-11-27	Theravance, Inc.	Compuestos que tienen actividad agonista del receptor beta2 adrenergico y antagonista del receptor muscarino.
RU2281769C2 (ru) *	2004-07-16	2006-08-20	Федеральное государственное научное учреждение Всероссийский научно-исследовательский ветеринарный институт	Средство для лечения дерматомикозов
GB0426164D0 (en) *	2004-11-29	2004-12-29	Novartis Ag	Organic compounds
RU2288715C2 (ru) *	2005-01-11	2006-12-10	ГОУ ВПО "Воронежская государственная медицинская академия им. Н.Н. Бурденко Министерства здравоохранения Российской Федерации"	Способ лечения бронхиальной астмы
TW200738658A (en)	2005-08-09	2007-10-16	Astrazeneca Ab	Novel compounds
RU2415136C2 (ru) *	2005-08-09	2011-03-27	Астразенека Аб	Новые производные бензотиазолона
TW200738659A (en) *	2005-08-29	2007-10-16	Astrazeneca Ab	Novel compounds
TW200745067A (en)	2006-03-14	2007-12-16	Astrazeneca Ab	Novel compounds
RU2455295C2 (ru) *	2006-12-20	2012-07-10	АстраЗенека AБ	4-ГИДРОКСИ-2-ОКСО-2,3-ДИГИДРО-1,3-БЕНЗОТИАЗОЛ-7-ИЛЬНЫЕ СОЕДИНЕНИЯ ДЛЯ МОДУЛЯЦИИ β2-АДРЕНОРЕЦЕПТОРНОЙ АКТИВНОСТИ
TW200833670A (en)	2006-12-20	2008-08-16	Astrazeneca Ab	Novel compounds 569
GB0702458D0 (en)	2007-02-08	2007-03-21	Astrazeneca Ab	Salts 668
GB0704000D0 (en) *	2007-03-01	2007-04-11	Astrazeneca Ab	Salts 670
WO2009154557A1 (en)	2008-06-18	2009-12-23	Astrazeneca Ab	Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders
CN102977050B (zh) *	2012-11-20	2015-04-22	浙江工业大学	一种2-苯并噻唑二甲缩醛和2-苯并噻唑甲醛的合成方法
CN106748930B (zh) *	2016-12-05	2019-03-15	三门峡奥科化工有限公司	3-巯基-1-丙醇的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4554284A (en) *	1984-09-12	1985-11-19	Smithkline Beckman Corporation	7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
IE914003A1 (en) *	1990-11-20	1992-05-20	Astra Pharma Prod	Biologically Active Amines

1992
- 1992-05-27 GB GB929211172A patent/GB9211172D0/en active Pending
1993
- 1993-05-05 PH PH46233A patent/PH31453A/en unknown
- 1993-05-25 ZA ZA933648A patent/ZA933648B/xx unknown
- 1993-05-25 IL IL10580193A patent/IL105801A/xx not_active IP Right Cessation
- 1993-05-26 TW TW082104181A patent/TW368501B/zh active
- 1993-05-26 MA MA23194A patent/MA22895A1/fr unknown
- 1993-05-26 DZ DZ930063A patent/DZ1694A1/fr active
- 1993-05-27 AT AT93913203T patent/ATE172726T1/de not_active IP Right Cessation
- 1993-05-27 AU AU43343/93A patent/AU675649B2/en not_active Ceased
- 1993-05-27 KR KR1019940704294A patent/KR100279132B1/ko not_active Expired - Fee Related
- 1993-05-27 WO PCT/GB1993/001095 patent/WO1993024473A1/en not_active Ceased
- 1993-05-27 CA CA002136553A patent/CA2136553C/en not_active Expired - Fee Related
- 1993-05-27 ES ES93913203T patent/ES2123652T3/es not_active Expired - Lifetime
- 1993-05-27 SK SK1433-94A patent/SK281282B6/sk unknown
- 1993-05-27 FI FI945538A patent/FI945538A0/fi unknown
- 1993-05-27 MY MYPI93000997A patent/MY131193A/en unknown
- 1993-05-27 PL PL93317714A patent/PL172807B1/pl unknown
- 1993-05-27 RU RU94046093A patent/RU2114108C1/ru active
- 1993-05-27 JP JP06500327A patent/JP3094452B2/ja not_active Expired - Fee Related
- 1993-05-27 NZ NZ253190A patent/NZ253190A/en unknown
- 1993-05-27 CZ CZ19942916A patent/CZ286905B6/cs not_active IP Right Cessation
- 1993-05-27 DK DK93913203T patent/DK0649418T3/da active
- 1993-05-27 PL PL93306303A patent/PL172904B1/pl unknown
- 1993-05-27 MX MX9303145A patent/MX9303145A/es not_active IP Right Cessation
- 1993-05-27 SG SG1996006829A patent/SG48068A1/en unknown
- 1993-05-27 UA UA94119105A patent/UA27901C2/uk unknown
- 1993-05-27 DE DE69321835T patent/DE69321835T2/de not_active Expired - Fee Related
- 1993-05-27 EP EP93913203A patent/EP0649418B1/en not_active Expired - Lifetime
- 1993-05-27 CN CN93108209A patent/CN1036393C/zh not_active Expired - Fee Related
- 1993-05-27 HU HU9403387A patent/HUT71124A/hu unknown
1994
- 1994-11-24 NO NO944509A patent/NO304739B1/no not_active IP Right Cessation
1995
- 1995-06-27 HU HU95P/P00462P patent/HU211947A9/hu unknown
1999
- 1999-10-28 LV LVP-99-152A patent/LV12443B/en unknown

Also Published As

Publication number	Publication date
DE69321835D1 (de)	1998-12-03
CN1085899A (zh)	1994-04-27
ATE172726T1 (de)	1998-11-15
DZ1694A1 (fr)	2002-02-17
SK281282B6 (sk)	2001-02-12
EP0649418B1 (en)	1998-10-28
ES2123652T3 (es)	1999-01-16
JPH08503923A (ja)	1996-04-30
SG48068A1 (en)	1998-04-17
FI945538L (fi)	1994-11-25
MX9303145A (es)	1994-06-30
HUT71124A (en)	1995-11-28
NZ253190A (en)	1995-12-21
IL105801A0 (en)	1993-09-22
MY131193A (en)	2007-07-31
DK0649418T3 (da)	1999-07-12
AU675649B2 (en)	1997-02-13
CZ291694A3 (en)	1995-03-15
ZA933648B (en)	1993-11-25
SK143394A3 (en)	1995-06-07
NO944509D0 (no)	1994-11-24
GB9211172D0 (en)	1992-07-08
CN1036393C (zh)	1997-11-12
DE69321835T2 (de)	1999-05-12
LV12443A (en)	2000-03-20
TW368501B (en)	1999-09-01
HU9403387D0 (en)	1995-02-28
LV12443B (en)	2000-06-20
CZ286905B6 (en)	2000-08-16
FI945538A7 (fi)	1994-11-25
PL172904B1 (pl)	1997-12-31
WO1993024473A1 (en)	1993-12-09
MA22895A1 (fr)	1993-12-31
KR100279132B1 (ko)	2001-01-15
AU4334393A (en)	1993-12-30
PH31453A (en)	1998-11-03
EP0649418A1 (en)	1995-04-26
NO944509L (no)	1994-11-24
PL172807B1 (pl)	1997-11-28
CA2136553A1 (en)	1993-12-09
HU211947A9 (en)	1996-01-29
RU2114108C1 (ru)	1998-06-27
JP3094452B2 (ja)	2000-10-03
CA2136553C (en)	2000-08-15
RU94046093A (ru)	1996-09-27
IL105801A (en)	1997-01-10
FI945538A0 (fi)	1994-11-25
NO304739B1 (no)	1999-02-08

Publication	Publication Date	Title
ATE211743T1 (de)	2002-01-15	Substituierte 3-aminochinuclidine
MX9504332A (es)	1997-03-29	Derivados de amino(tio)eter y procedimiento para su preparacion.
MX9100308A (es)	1992-02-28	Derivados de quinuclidina
EA199800340A1 (ru)	1998-10-29	Производные пиримидина как антагонисты 5нт2с
ES2138691T3 (es)	2000-01-16	Procedimiento para la obtencion de derivados de n-acil-5-fluorocitidina.
BR9916307A (pt)	2002-01-15	Derivados quinolina
BG101110A (bg)	1997-08-29	Заместени пиримидинови съединения и тяхното използване
NO944578L (no)	1995-06-06	Eksitatoriske aminosyre reseptor antagonister
EA200100204A1 (ru)	2001-08-27	Фармацевтические агенты для лечения болезни паркинсона, ганв и микроаденом
MX9301197A (es)	1993-09-01	Derivados de indol.
EA200200207A1 (ru)	2002-08-29	Применение антагонистов cgrp и ингибиторов высвобождения cgrp для устранения приливов в период менопаузы
ES2101858T3 (es)	1997-07-16	Derivados de geneserina como inhibidores de colinesterasa.
FI944727L (fi)	1994-10-07	Indolijohdannaisia 5-HT1:n kaltaisina agonisteina
ATE242220T1 (de)	2003-06-15	Benzimidazolderivate mit dopaminerger wirkung
UA27713C2 (uk)	2000-10-16	Амідинові похідні бензолу, що мають гіпоглікемічну активність, та їх фармацевтично прийнятні солі
DK407885A (da)	1986-03-13	7-(2-(dialkylamino)ethyl)-4-hydroxy-1,3-benzimidazol-2-oner
TR27833A (tr)	1995-08-31	Antelmintik'lerin uygulanmasina mahsus ''pour-on'' formülasyonu.
ATE103182T1 (de)	1994-04-15	Antimikrobielle zusammensetzungen.
AR005008A1 (es)	1999-04-07	Compuestos benzotiazolona etanaminas, procedimiento e intermediarios para su preparacion y su uso en la preparacion de medicamentos
ITMI920979A0 (it)	1992-04-24	N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.
NO913644D0 (no)	1991-09-16	Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
ATE74505T1 (de)	1992-04-15	Schmerzpraeparat.
AR021502A1 (es)	2002-07-24	Uso de derivados de azabicicloalcanos n-sustituidos para el tratamiento de enfermedades del sistema central nervioso
NO890245L (no)	1989-01-19	Isoxazoler med nootrop aktivitet.
SU1783774A1 (ru)	2001-06-10	Натриевая соль n-(3-хлорбутен-2-ил)антраниловой кислоты, проявляющая противовоспалительную и анальгетическую активность