UA64714C2 - Dervatives of substituted 2-methyl benzimidazole, a method for preparing thereof, a pharmaceutical composition and a method for treatment of gastrointestinal diseases - Google Patents

Dervatives of substituted 2-methyl benzimidazole, a method for preparing thereof, a pharmaceutical composition and a method for treatment of gastrointestinal diseases Download PDF

Info

Publication number: UA64714C2
Authority: UA; Ukraine
Prior art keywords: compound according; compound; formula; pharmaceutically acceptable; acceptable salt
Prior art date: 1996-06-10

Application number

UA98126867A

Other languages

English (en)

Ukrainian (uk)

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-10

Filing date

1997-05-06

Publication date

2004-03-15

1997-05-06 Application filed by Astra Ab filed Critical Astra Ab

2004-03-15 Publication of UA64714C2 publication Critical patent/UA64714C2/uk

Links

238000000034 method Methods 0.000 title claims description 11
239000008194 pharmaceutical composition Substances 0.000 title claims description 10
208000018522 Gastrointestinal disease Diseases 0.000 title claims description 8
LDZYRENCLPUXAX-UHFFFAOYSA-N 2-methyl-1h-benzimidazole Chemical class C1=CC=C2NC(C)=NC2=C1 LDZYRENCLPUXAX-UHFFFAOYSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 claims abstract description 16
230000002265 prevention Effects 0.000 claims abstract description 7
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 6
230000027119 gastric acid secretion Effects 0.000 claims abstract description 5
150000001875 compounds Chemical class 0.000 claims description 112
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125000000623 heterocyclic group Chemical group 0.000 claims description 11
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VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical group Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 5
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235000013355 food flavoring agent Nutrition 0.000 description 1
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150000004678 hydrides Chemical class 0.000 description 1
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238000005342 ion exchange Methods 0.000 description 1
125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
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SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 description 1
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VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
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GRNIQEQKQMSSSZ-UHFFFAOYSA-N n-[(2,6-diethylphenyl)methyl]-2-methyl-1h-benzimidazol-4-amine Chemical compound CCC1=CC=CC(CC)=C1CNC1=CC=CC2=C1NC(C)=N2 GRNIQEQKQMSSSZ-UHFFFAOYSA-N 0.000 description 1
QTGWIBNVFTVALF-UHFFFAOYSA-N n-benzyl-2-methyl-1h-benzimidazol-4-amine Chemical compound C=12NC(C)=NC2=CC=CC=1NCC1=CC=CC=C1 QTGWIBNVFTVALF-UHFFFAOYSA-N 0.000 description 1
125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
229960000564 nitrofurantoin Drugs 0.000 description 1
NXFQHRVNIOXGAQ-YCRREMRBSA-N nitrofurantoin Chemical compound O1C([N+](=O)[O-])=CC=C1\C=N\N1C(=O)NC(=O)C1 NXFQHRVNIOXGAQ-YCRREMRBSA-N 0.000 description 1
OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 description 1
229960001180 norfloxacin Drugs 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
210000000496 pancreas Anatomy 0.000 description 1
229920002866 paraformaldehyde Polymers 0.000 description 1
ANRIQLNBZQLTFV-DZUOILHNSA-N pentagastrin Chemical compound C([C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1[C]2C=CC=CC2=NC=1)NC(=O)CCNC(=O)OC(C)(C)C)CCSC)C(N)=O)C1=CC=CC=C1 ANRIQLNBZQLTFV-DZUOILHNSA-N 0.000 description 1
229960000444 pentagastrin Drugs 0.000 description 1
125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
235000019271 petrolatum Nutrition 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
239000012071 phase Substances 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
230000036470 plasma concentration Effects 0.000 description 1
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150000007660 quinolones Chemical class 0.000 description 1
238000011084 recovery Methods 0.000 description 1
238000010992 reflux Methods 0.000 description 1
238000012552 review Methods 0.000 description 1
235000019204 saccharin Nutrition 0.000 description 1
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
229940081974 saccharin Drugs 0.000 description 1
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
230000007017 scission Effects 0.000 description 1
238000010898 silica gel chromatography Methods 0.000 description 1
229910000033 sodium borohydride Inorganic materials 0.000 description 1
239000012279 sodium borohydride Substances 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
229940045902 sodium stearyl fumarate Drugs 0.000 description 1
HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
239000007790 solid phase Substances 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
238000005728 strengthening Methods 0.000 description 1
150000003460 sulfonic acids Chemical class 0.000 description 1
239000000829 suppository Substances 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
239000006188 syrup Substances 0.000 description 1
239000008399 tap water Substances 0.000 description 1
235000020679 tap water Nutrition 0.000 description 1
125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
229960002180 tetracycline Drugs 0.000 description 1
229930101283 tetracycline Natural products 0.000 description 1
229940040944 tetracyclines Drugs 0.000 description 1
DDFYFBUWEBINLX-UHFFFAOYSA-M tetramethylammonium bromide Chemical compound [Br-].C[N+](C)(C)C DDFYFBUWEBINLX-UHFFFAOYSA-M 0.000 description 1
239000002562 thickening agent Substances 0.000 description 1
238000004448 titration Methods 0.000 description 1
230000001562 ulcerogenic effect Effects 0.000 description 1
235000019871 vegetable fat Nutrition 0.000 description 1
239000001993 wax Substances 0.000 description 1
239000002132 β-lactam antibiotic Substances 0.000 description 1
229940124586 β-lactam antibiotics Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

UA98126867A 1996-06-10 1997-05-06 Dervatives of substituted 2-methyl benzimidazole, a method for preparing thereof, a pharmaceutical composition and a method for treatment of gastrointestinal diseases UA64714C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9602286A SE9602286D0 (sv)	1996-06-10	1996-06-10	New compounds
PCT/SE1997/000991 WO1997047603A1 (fr)	1996-06-10	1997-06-05	Nouveaux composes

Publications (1)

Publication Number	Publication Date
UA64714C2 true UA64714C2 (en)	2004-03-15

Family

ID=20402945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA98126867A UA64714C2 (en)	1996-06-10	1997-05-06	Dervatives of substituted 2-methyl benzimidazole, a method for preparing thereof, a pharmaceutical composition and a method for treatment of gastrointestinal diseases

Country Status (32)

Country	Link
US (1)	US6465505B1 (fr)
EP (1)	EP0906288B1 (fr)
JP (1)	JP2000512291A (fr)
CN (1)	CN1101385C (fr)
AR (1)	AR007352A1 (fr)
AT (1)	ATE227273T1 (fr)
AU (1)	AU712173B2 (fr)
BR (1)	BR9709666A (fr)
CA (1)	CA2256687C (fr)
CZ (1)	CZ291469B6 (fr)
DE (1)	DE69716904T2 (fr)
DK (1)	DK0906288T3 (fr)
EE (1)	EE03682B1 (fr)
ES (1)	ES2184097T3 (fr)
HU (1)	HUP0002952A3 (fr)
ID (1)	ID18431A (fr)
IL (1)	IL127432A0 (fr)
IS (1)	IS1864B (fr)
MY (1)	MY119012A (fr)
NO (1)	NO311672B1 (fr)
NZ (1)	NZ332965A (fr)
PL (1)	PL330525A1 (fr)
PT (1)	PT906288E (fr)
RU (1)	RU2184113C2 (fr)
SA (1)	SA97180427B1 (fr)
SE (1)	SE9602286D0 (fr)
SK (1)	SK282704B6 (fr)
TR (1)	TR199802554T2 (fr)
TW (1)	TW470742B (fr)
UA (1)	UA64714C2 (fr)
WO (1)	WO1997047603A1 (fr)
ZA (1)	ZA974681B (fr)

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Publication number	Priority date	Publication date	Assignee	Title
SE9704404D0 (sv)	1997-11-28	1997-11-28	Astra Ab	New compounds
AR043063A1 (es) *	2002-12-13	2005-07-13	Altana Pharma Ag	Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
WO2004087701A1 (fr) *	2003-04-04	2004-10-14	Altana Pharma Ag	Benzimidazoles cycliques
AR046893A1 (es) *	2003-12-16	2005-12-28	Altana Pharma Ag	Bencimidazoles triciclicos
AR048869A1 (es) *	2004-04-26	2006-06-07	Altana Pharma Ag	Bencimidazoles triciclicos
AR049168A1 (es) *	2004-05-18	2006-07-05	Altana Pharma Ag	Derivados de benzimidazol
AU2005251943A1 (en) *	2004-06-09	2005-12-22	Altana Pharma Ag	Substituted tricyclic benzimidazoles
CA2582256A1 (fr) *	2004-10-01	2006-04-13	Altana Pharma Ag	Benzimidazoles tricycliques substitues
AR051041A1 (es) *	2004-10-04	2006-12-13	Altana Pharma Ag	Bencimidazoles triciclicos condensados
DE602006009105D1 (de) *	2005-06-14	2009-10-22	Raqualia Pharma Inc	Chroman-substituierte benzimidazolderivate als säurepumpenantagonisten
JP2009504798A (ja) *	2005-08-22	2009-02-05	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	同位体置換されたベンゾイミダゾール誘導体
KR101088247B1 (ko) *	2005-12-19	2011-11-30	라퀄리아 파마 인코포레이티드	크로메인 치환된 벤즈이미다졸 및 이들의 산 펌프억제제로서의 용도
WO2007072142A2 (fr) *	2005-12-19	2007-06-28	Pfizer Japan Inc.	Dérivés de benzimidazole-5-carboxamide
US20080027044A1 (en) *	2006-06-13	2008-01-31	Kim Lewis	Prodrug antibiotic screens
EP2092590A4 (fr) *	2006-11-10	2011-01-12	Univ California	Polymérisation avec greffage induite par plasma à pression atmosphérique
WO2008156610A2 (fr) *	2007-06-13	2008-12-24	Northeastern University	Composés antibiotiques
WO2008151927A2 (fr) *	2007-06-15	2008-12-18	Nycomed Gmbh	Dérivés de benzimidazole à substitution 6-n pharmaceutiquement actifs
US8445076B2 (en) *	2008-06-11	2013-05-21	The Regents Of The University Of California	Fouling and scaling resistant nano-structured reverse osmosis membranes
KR101472686B1 (ko)	2013-07-09	2014-12-16	씨제이헬스케어 주식회사	벤즈이미다졸 유도체의 제조방법
EP4620957A1 (fr) *	2024-03-22	2025-09-24	Eberhard Karls Universität Tübingen	Composés d'imidazo[4,5-b]pyridin-7-amine se liant à l'aurora kinase a et leurs utilisations

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Publication number	Priority date	Publication date	Assignee	Title
SU1183503A1 (ru) *	1983-07-08	1985-10-07	Ростовский Ордена Трудового Красного Знамени Государственный Университет Им.М.А.Суслова	Способ получени @ -замещенных имидазолов или бензимидазолов
SE8604566D0 (sv) *	1986-10-27	1986-10-27	Haessle Ab	Novel compunds
ATE63550T1 (de) *	1986-10-29	1991-06-15	Binder Dieter	Neue 1-/ 3-(2-dialkylaminoaethoxy)-2-thienyl/-3phenyl-1-propanone und ihre saeureadditionssalze und verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
WO1996004251A1 (fr) *	1994-08-03	1996-02-15	Fujisawa Pharmaceutical Co., Ltd.	Compose heterocyclique
SE9700661D0 (sv)	1997-02-25	1997-02-25	Astra Ab	New compounds

1996
- 1996-06-10 SE SE9602286A patent/SE9602286D0/xx unknown
1997
- 1997-05-06 UA UA98126867A patent/UA64714C2/uk unknown
- 1997-05-28 ZA ZA974681A patent/ZA974681B/xx unknown
- 1997-05-29 TW TW086107338A patent/TW470742B/zh active
- 1997-05-30 AR ARP970102342A patent/AR007352A1/es unknown
- 1997-06-05 HU HU0002952A patent/HUP0002952A3/hu unknown
- 1997-06-05 CA CA002256687A patent/CA2256687C/fr not_active Expired - Fee Related
- 1997-06-05 ES ES97927552T patent/ES2184097T3/es not_active Expired - Lifetime
- 1997-06-05 AU AU31992/97A patent/AU712173B2/en not_active Ceased
- 1997-06-05 US US08/875,132 patent/US6465505B1/en not_active Expired - Lifetime
- 1997-06-05 AT AT97927552T patent/ATE227273T1/de not_active IP Right Cessation
- 1997-06-05 ID IDP971913A patent/ID18431A/id unknown
- 1997-06-05 DK DK97927552T patent/DK0906288T3/da active
- 1997-06-05 RU RU99100397/04A patent/RU2184113C2/ru not_active IP Right Cessation
- 1997-06-05 SK SK1654-98A patent/SK282704B6/sk unknown
- 1997-06-05 BR BR9709666-0A patent/BR9709666A/pt not_active Application Discontinuation
- 1997-06-05 IL IL12743297A patent/IL127432A0/xx unknown
- 1997-06-05 PT PT97927552T patent/PT906288E/pt unknown
- 1997-06-05 CZ CZ19984039A patent/CZ291469B6/cs not_active IP Right Cessation
- 1997-06-05 EE EE9800430A patent/EE03682B1/xx not_active IP Right Cessation
- 1997-06-05 PL PL97330525A patent/PL330525A1/xx unknown
- 1997-06-05 NZ NZ332965A patent/NZ332965A/xx unknown
- 1997-06-05 EP EP97927552A patent/EP0906288B1/fr not_active Expired - Lifetime
- 1997-06-05 CN CN97196704A patent/CN1101385C/zh not_active Expired - Fee Related
- 1997-06-05 TR TR1998/02554T patent/TR199802554T2/xx unknown
- 1997-06-05 JP JP10501511A patent/JP2000512291A/ja not_active Ceased
- 1997-06-05 WO PCT/SE1997/000991 patent/WO1997047603A1/fr not_active Ceased
- 1997-06-05 DE DE69716904T patent/DE69716904T2/de not_active Expired - Fee Related
- 1997-06-09 MY MYPI97002563A patent/MY119012A/en unknown
- 1997-09-24 SA SA97180427A patent/SA97180427B1/ar unknown
1998
- 1998-11-25 IS IS4907A patent/IS1864B/is unknown
- 1998-12-09 NO NO19985764A patent/NO311672B1/no unknown

Also Published As

Publication number	Publication date
AR007352A1 (es)	1999-10-27
PT906288E (pt)	2003-02-28
EE9800430A (et)	1999-06-15
HUP0002952A3 (en)	2001-11-28
IS1864B (is)	2003-04-15
NO311672B1 (no)	2002-01-02
CA2256687A1 (fr)	1997-12-18
ZA974681B (en)	1998-08-25
SK165498A3 (en)	1999-06-11
US6465505B1 (en)	2002-10-15
AU3199297A (en)	1998-01-07
TW470742B (en)	2002-01-01
SA97180427B1 (ar)	2005-10-15
EP0906288B1 (fr)	2002-11-06
CZ291469B6 (cs)	2003-03-12
SE9602286D0 (sv)	1996-06-10
ES2184097T3 (es)	2003-04-01
BR9709666A (pt)	2000-05-09
IS4907A (is)	1998-11-25
AU712173B2 (en)	1999-10-28
CA2256687C (fr)	2005-08-09
ID18431A (id)	1998-04-09
ATE227273T1 (de)	2002-11-15
NO985764D0 (no)	1998-12-09
SK282704B6 (sk)	2002-11-06
CN1226236A (zh)	1999-08-18
PL330525A1 (en)	1999-05-24
TR199802554T2 (xx)	1999-03-22
DE69716904T2 (de)	2003-07-24
HK1017351A1 (en)	1999-11-19
DE69716904D1 (de)	2002-12-12
IL127432A0 (en)	1999-10-28
RU2184113C2 (ru)	2002-06-27
WO1997047603A1 (fr)	1997-12-18
JP2000512291A (ja)	2000-09-19
MY119012A (en)	2005-03-31
EE03682B1 (et)	2002-04-15
CN1101385C (zh)	2003-02-12
HUP0002952A2 (hu)	2001-05-28
NO985764L (no)	1998-12-09
CZ403998A3 (cs)	1999-05-12
NZ332965A (en)	2000-05-26
DK0906288T3 (da)	2003-01-06
EP0906288A1 (fr)	1999-04-07

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RU2235725C2 (ru)	2004-09-10	Производные имидазопиридина, способ их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты и способ лечения состояний, в которые вовлечено инфицирование h.pylori
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US4520025A (en)	1985-05-28	Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
HUP0000720A2 (hu)	2000-10-28	Imidazo [1,2-a] piridinszármazékok, eljárás előállításukra, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
IE840655L (en)	1984-09-16	1,3-thiazolidine derivatives
RU2294935C2 (ru)	2007-03-10	Имидазопиридиновые производные для применения в терапии в качестве лекарственного средства, ингибирующего протонный насос, и промежуточные соединения для их получения
BG97438A (bg)	1994-03-24	4-алкилимидазолови съединения
US4596806A (en)	1986-06-24	7-piperidino-1,2,3,5-tetrahydroimidazo[2,1-b]-quinazolin-2-one having platelet aggregation inhibitory activity
US4599346A (en)	1986-07-08	Propan-2-ol derivatives, a process for their production and medicaments containing these compounds
RU2142454C1 (ru)	1999-12-10	Производные 4-амино-3-ацилхинолина, способ их получения, фармацевтический препарат на их основе, способ получения фармацевтического препарата и промежуточное соединение
KR100487029B1 (ko)	2005-11-25	신규화합물
US4108999A (en)	1978-08-22	Thiazolo[3,4-b]isoquinoline derivatives, pharmaceutical compositions containing them and pharmaceutical methods using them
CA2205896A1 (fr)	1996-06-13	Composes destines a inhiber la secretion d'acide gastrique
AU697006C (en)	1999-05-06	Compounds for inhibition of gastric acid secretion
MXPA97004136A (en)	1998-02-01	Compounds for inhibition of gastr acid secretion
HK1017351B (en)	2003-02-21	New compounds
JPH0613486B2 (ja)	1994-02-23	ピリミドン誘導体及びその医薬的に許容される塩
JPH03148262A (ja)	1991-06-25	イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤