UA72890C2 - A crystalline form of osanetant (variants), a method for the preparation thereof (variants) and a pharmaceutical composition - Google Patents

A crystalline form of osanetant (variants), a method for the preparation thereof (variants) and a pharmaceutical composition

Info

Publication number: UA72890C2
Authority: UA; Ukraine
Prior art keywords: variants; osanetant; preparation; pharmaceutical composition; crystalline form
Prior art date: 1998-08-05

Application number

UA2001010591A

Other languages

English (en)

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-05

Filing date

1999-08-03

Publication date

2005-05-16

1999-08-03 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2005-05-16 Publication of UA72890C2 publication Critical patent/UA72890C2/xx

Links

DZOJBGLFWINFBF-UMSFTDKQSA-N osanetant Chemical compound C([C@](C1)(CCCN2CCC(CC2)(N(C(C)=O)C)C=2C=CC=CC=2)C=2C=C(Cl)C(Cl)=CC=2)CCN1C(=O)C1=CC=CC=C1 DZOJBGLFWINFBF-UMSFTDKQSA-N 0.000 title abstract 5
229950009875 osanetant Drugs 0.000 title abstract 4
239000008194 pharmaceutical composition Substances 0.000 title 1
SRSXLGNVWSONIS-UHFFFAOYSA-M benzenesulfonate Chemical compound [O-]S(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-M 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

UA2001010591A 1998-08-05 1999-08-03 A crystalline form of osanetant (variants), a method for the preparation thereof (variants) and a pharmaceutical composition UA72890C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9810107A FR2782082B3 (fr)	1998-08-05	1998-08-05	Formes cristallines de (r)-(+)-n-[[3-[1-benzoyl-3-(3,4- dichlorophenyl)piperidin-3-yl]prop-1-yl]-4-phenylpiperidin-4 -yl]-n-methylacetamide (osanetant) et procede pour la preparation dudit compose
PCT/FR1999/001914 WO2000007987A1 (fr)	1998-08-05	1999-08-03	Formes cristallines du osanetant

Publications (1)

Publication Number	Publication Date
UA72890C2 true UA72890C2 (en)	2005-05-16

Family

ID=9529458

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA2001010591A UA72890C2 (en)	1998-08-05	1999-08-03	A crystalline form of osanetant (variants), a method for the preparation thereof (variants) and a pharmaceutical composition

Country Status (31)

Country	Link
US (1)	US7041679B2 (de)
EP (1)	EP1102747B1 (de)
JP (1)	JP3807938B2 (de)
KR (1)	KR100571944B1 (de)
CN (1)	CN1114592C (de)
AR (1)	AR019953A1 (de)
AT (1)	ATE243197T1 (de)
AU (1)	AU748177B2 (de)
BR (1)	BR9913357A (de)
CA (1)	CA2339007A1 (de)
CO (1)	CO5070576A1 (de)
DE (1)	DE69908951T2 (de)
DK (1)	DK1102747T3 (de)
DZ (1)	DZ3074A1 (de)
EA (1)	EA003205B1 (de)
EE (1)	EE04274B1 (de)
ES (1)	ES2200535T3 (de)
FR (1)	FR2782082B3 (de)
HU (1)	HUP0103134A3 (de)
IS (1)	IS5821A (de)
MY (1)	MY121447A (de)
NO (1)	NO320645B1 (de)
NZ (1)	NZ509561A (de)
PL (1)	PL345999A1 (de)
PT (1)	PT1102747E (de)
SK (1)	SK1742001A3 (de)
TR (1)	TR200100261T2 (de)
TW (1)	TW527354B (de)
UA (1)	UA72890C2 (de)
WO (1)	WO2000007987A1 (de)
YU (1)	YU8601A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE0100902D0 (sv)	2001-03-15	2001-03-15	Astrazeneca Ab	Compounds
SE0202539D0 (sv)	2002-08-27	2002-08-27	Astrazeneca Ab	Compounds
US7648992B2 (en) *	2004-07-05	2010-01-19	Astrazeneca Ab	Hydantoin derivatives for the treatment of obstructive airway diseases
SE0401762D0 (sv) *	2004-07-05	2004-07-05	Astrazeneca Ab	Novel compounds
SE0403085D0 (sv) *	2004-12-17	2004-12-17	Astrazeneca Ab	Novel componds
SE0403086D0 (sv) *	2004-12-17	2004-12-17	Astrazeneca Ab	Compounds
TW200800954A (en) *	2006-03-16	2008-01-01	Astrazeneca Ab	Novel crystal modifications
TW200831488A (en) *	2006-11-29	2008-08-01	Astrazeneca Ab	Novel compounds
US20240336565A1 (en) *	2021-07-02	2024-10-10	Acer Therapeutics, Inc.	Solid forms of osanetant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2719311B1 (fr)	1994-03-18	1998-06-26	Sanofi Sa	Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic.
JPH1053576A (ja) *	1996-06-07	1998-02-24	Eisai Co Ltd	塩酸ドネペジルの多形結晶およびその製造法
EP0915849A2 (de) *	1996-08-05	1999-05-19	Smithkline Beecham S.p.A.	Verfahren zur herstellung von 3,3-disubstituierten piperidinen
US6040316A (en) *	1996-09-16	2000-03-21	Warner-Lambert Company	3-alkyl-3-phenyl-piperidines
FR2757543B1 (fr) *	1996-12-23	1999-04-02	Sanofi Sa	Procede pour la cristallisation d'un derive de tetrahydropyridine et formes cristallines ainsi obtenues

1998
- 1998-08-05 FR FR9810107A patent/FR2782082B3/fr not_active Expired - Lifetime
1999
- 1999-07-25 DZ DZ990156A patent/DZ3074A1/xx active
- 1999-07-28 AR ARP990103741A patent/AR019953A1/es unknown
- 1999-08-03 SK SK174-2001A patent/SK1742001A3/sk unknown
- 1999-08-03 NZ NZ509561A patent/NZ509561A/xx unknown
- 1999-08-03 WO PCT/FR1999/001914 patent/WO2000007987A1/fr not_active Ceased
- 1999-08-03 EP EP99936672A patent/EP1102747B1/de not_active Expired - Lifetime
- 1999-08-03 AT AT99936672T patent/ATE243197T1/de not_active IP Right Cessation
- 1999-08-03 DK DK99936672T patent/DK1102747T3/da active
- 1999-08-03 BR BR9913357-1A patent/BR9913357A/pt not_active IP Right Cessation
- 1999-08-03 HU HU0103134A patent/HUP0103134A3/hu unknown
- 1999-08-03 DE DE69908951T patent/DE69908951T2/de not_active Expired - Fee Related
- 1999-08-03 PL PL99345999A patent/PL345999A1/xx not_active Application Discontinuation
- 1999-08-03 YU YU8601A patent/YU8601A/sh unknown
- 1999-08-03 MY MYPI99003297A patent/MY121447A/en unknown
- 1999-08-03 CA CA002339007A patent/CA2339007A1/en not_active Abandoned
- 1999-08-03 JP JP2000563621A patent/JP3807938B2/ja not_active Expired - Fee Related
- 1999-08-03 TR TR2001/00261T patent/TR200100261T2/xx unknown
- 1999-08-03 UA UA2001010591A patent/UA72890C2/xx unknown
- 1999-08-03 AU AU51685/99A patent/AU748177B2/en not_active Ceased
- 1999-08-03 KR KR1020017001460A patent/KR100571944B1/ko not_active Expired - Fee Related
- 1999-08-03 ES ES99936672T patent/ES2200535T3/es not_active Expired - Lifetime
- 1999-08-03 EE EEP200100070A patent/EE04274B1/xx not_active IP Right Cessation
- 1999-08-03 EA EA200100096A patent/EA003205B1/ru not_active IP Right Cessation
- 1999-08-03 PT PT99936672T patent/PT1102747E/pt unknown
- 1999-08-03 CN CN99810182A patent/CN1114592C/zh not_active Expired - Fee Related
- 1999-08-04 CO CO99049286A patent/CO5070576A1/es unknown
- 1999-08-04 TW TW088113235A patent/TW527354B/zh not_active IP Right Cessation
2001
- 2001-01-23 IS IS5821A patent/IS5821A/is unknown
- 2001-02-01 NO NO20010553A patent/NO320645B1/no unknown
2003
- 2003-08-28 US US10/651,313 patent/US7041679B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MY121447A (en)	2006-01-28
EE200100070A (et)	2002-06-17
KR100571944B1 (ko)	2006-04-18
CN1314888A (zh)	2001-09-26
JP3807938B2 (ja)	2006-08-09
EA200100096A1 (ru)	2001-08-27
HUP0103134A3 (en)	2003-03-28
SK1742001A3 (en)	2001-11-06
DK1102747T3 (da)	2003-09-29
ES2200535T3 (es)	2004-03-01
TW527354B (en)	2003-04-11
CA2339007A1 (en)	2000-02-17
NO20010553D0 (no)	2001-02-01
EA003205B1 (ru)	2003-02-27
NZ509561A (en)	2002-10-25
TR200100261T2 (tr)	2001-06-21
DE69908951D1 (de)	2003-07-24
BR9913357A (pt)	2001-05-15
IS5821A (is)	2001-01-23
PT1102747E (pt)	2003-09-30
FR2782082B3 (fr)	2000-09-22
DE69908951T2 (de)	2004-05-19
EP1102747A1 (de)	2001-05-30
DZ3074A1 (fr)	2004-07-20
HUP0103134A2 (en)	2002-06-29
EP1102747B1 (de)	2003-06-18
WO2000007987A1 (fr)	2000-02-17
JP2002522419A (ja)	2002-07-23
US7041679B2 (en)	2006-05-09
KR20010072220A (ko)	2001-07-31
AU748177B2 (en)	2002-05-30
PL345999A1 (en)	2002-01-14
CO5070576A1 (es)	2001-08-28
EE04274B1 (et)	2004-04-15
YU8601A (sh)	2003-07-07
US20040044215A1 (en)	2004-03-04
FR2782082A1 (fr)	2000-02-11
NO20010553L (no)	2001-04-05
AU5168599A (en)	2000-02-28
NO320645B1 (no)	2006-01-09
ATE243197T1 (de)	2003-07-15
AR019953A1 (es)	2002-03-27
CN1114592C (zh)	2003-07-16
HK1035535A1 (en)	2001-11-30

Similar Documents

Publication	Publication Date	Title
IL111960A (en)	1999-12-22	Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
HUP9701281A2 (en)	1997-11-28	Piperidine derivatives as neurokinin antagonists and pharmaceutical compositions containing them
UA72890C2 (en)	2005-05-16	A crystalline form of osanetant (variants), a method for the preparation thereof (variants) and a pharmaceutical composition
NZ334017A (en)	2000-04-28	1,4-di-substituted piperidines and use in combination with acetylcholinesterase inhibitors for treating cognitive disorders
AU5475896A (en)	1996-12-19	Dihydropyridine NPY antagonists: piperidine derivatives
MX9703025A (es)	1997-10-31	Proceso para preparar levobupivacaina y sus analogos.
HUP0900417A3 (en)	2012-12-28	Polymorphs of donepezil hydrochloride and process for production and pharmaceutical compositions containing them
SI1513528T1 (sl)	2009-10-31	Farmacevtski sestavek, ki vsebuje stabilizirano amorfno obliko donepezilijevega hidroklorida
HUT63384A (en)	1993-08-30	Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
SI2157083T1 (sl)	2016-01-29	Farmacevtske sestave, vsebujoče kristalno obliko (i) lerkanidipin hidroklorida
NO990721L (no)	1999-04-20	Stabil ikke-hygroskopisk krystallinsk form av N-[N-N-(4-(piperidin-4-yl)butanoyl)-N-etylglysyl]forbindelser
AU2455888A (en)	1989-05-04	4-phenyl-4-(n-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
NO20002450L (no)	2000-07-14	Sammenstilling av aktive bestanddeler, særlig tetrahydropyridiner og acetylcholinesterase-inhiberende midler, for behandling av senil demens av Alzheimer-type
MY118015A (en)	2004-08-30	Method of crystallizing a tetrahydropyridine derivative and crystalline forms thereby obtained
RU99115083A (ru)	2001-05-27	1-фенилалкил-1,2,3,6-тетрагидропиридины для лечения болезни альцгеймера
HUP0105466A3 (en)	2002-11-28	Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride and pharmaceutical compositions containing them
NZ217818A (en)	1989-03-29	Substituted piperidine butanamide, n-oxides derivatives and pharmaceutical compositions
UA66776C2 (uk)	2004-06-15	Форма похідного тетрагідропіридину у вигляді мікрочастинок
BRPI0410934A (pt)	2006-06-27	método para a produção de chocolate, e, chocolate
HUP0302910A3 (en)	2008-02-28	Process for the racemisation of 1-benzyl-4-(4-fluorophenyl)-3-hydroxymethyl-1,2,3,6-tetrahydropyridine to be used as intermediate in the synthesis of paroxetine
CA2315696A1 (en)	1999-07-08	Pharmaceutical composition for oral administration
IL120870A0 (en)	1997-09-30	Carboxamide derivatives of pyrolidine piperidine and hexahydroazepine their preparation and pharmaceutical compositions containing them
HUP0002270A3 (en)	2001-12-28	Polymorphs of donepezil hydrochloride and process for production and pharmaceutical compositions containing them