UA74571C2 - Compounds of pyridazinylphenyl hydrazone being used in congestive heart failure - Google Patents

Compounds of pyridazinylphenyl hydrazone being used in congestive heart failure Download PDF

Info

Publication number
UA74571C2
UA74571C2 UA2002108100A UA2002108100A UA74571C2 UA 74571 C2 UA74571 C2 UA 74571C2 UA 2002108100 A UA2002108100 A UA 2002108100A UA 2002108100 A UA2002108100 A UA 2002108100A UA 74571 C2 UA74571 C2 UA 74571C2
Authority
UA
Ukraine
Prior art keywords
methyl
hydrogen
alkyl
hydroxy
pyridazin
Prior art date
Application number
UA2002108100A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of UA74571C2 publication Critical patent/UA74571C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
UA2002108100A 2000-03-13 2001-12-03 Compounds of pyridazinylphenyl hydrazone being used in congestive heart failure UA74571C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20000577A FI20000577A0 (fi) 2000-03-13 2000-03-13 Pyridatsinyylifenyylihydratsoneja
PCT/FI2001/000241 WO2001068611A1 (en) 2000-03-13 2001-03-12 Pyridazinyl phenyl hydrazones useful against congestive heart failure

Publications (1)

Publication Number Publication Date
UA74571C2 true UA74571C2 (en) 2006-01-16

Family

ID=8557913

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2002108100A UA74571C2 (en) 2000-03-13 2001-12-03 Compounds of pyridazinylphenyl hydrazone being used in congestive heart failure

Country Status (31)

Country Link
US (1) US6699868B2 (sr)
EP (1) EP1265871B1 (sr)
JP (1) JP2003527375A (sr)
KR (1) KR20030001379A (sr)
CN (1) CN1191241C (sr)
AR (1) AR027644A1 (sr)
AT (1) ATE317388T1 (sr)
AU (2) AU4657701A (sr)
BG (1) BG65859B1 (sr)
BR (1) BR0109136A (sr)
CA (1) CA2403188A1 (sr)
CZ (1) CZ20022997A3 (sr)
DE (1) DE60117131T2 (sr)
DK (1) DK1265871T3 (sr)
EA (1) EA005574B1 (sr)
EE (1) EE200200520A (sr)
ES (1) ES2256222T3 (sr)
FI (1) FI20000577A0 (sr)
HR (1) HRP20020816A2 (sr)
HU (1) HUP0300177A3 (sr)
IL (2) IL151492A0 (sr)
MX (1) MXPA02008997A (sr)
NO (1) NO324172B1 (sr)
NZ (1) NZ521162A (sr)
PL (1) PL357107A1 (sr)
RS (1) RS50439B (sr)
SI (1) SI1265871T1 (sr)
SK (1) SK287163B6 (sr)
UA (1) UA74571C2 (sr)
WO (1) WO2001068611A1 (sr)
ZA (1) ZA200206917B (sr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015228D0 (en) * 2000-06-21 2000-08-16 Portela & Ca Sa Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders
JP4561698B2 (ja) * 2002-02-19 2010-10-13 小野薬品工業株式会社 縮合ピリダジン誘導体化合物およびその化合物を有効成分として含有する薬剤
WO2004087641A1 (ja) * 2003-03-31 2004-10-14 Daiichi Pharmaceutical Co., Ltd. ヒドラゾン誘導体
GB0503962D0 (en) 2005-02-25 2005-04-06 Kudos Pharm Ltd Compounds
HRP20130044T1 (hr) 2006-07-25 2013-02-28 Cephalon, Inc. Derivati piridizinona
AU2008206903B2 (en) * 2007-01-17 2012-07-05 Orion Corporation Levosimendan for use in treating chronic valvular disease
CN103842334B (zh) * 2011-09-27 2016-06-29 日本瑞翁株式会社 聚合性化合物的制备中间体及其制备方法
CA2898440A1 (en) * 2013-01-18 2014-07-24 Bristol-Myers Squibb Company Phthalazinones and isoquinolinones as rock inhibitors
TW202005643A (zh) * 2018-06-08 2020-02-01 日商日產化學股份有限公司 激酶抑制劑

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531658A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
US5185332A (en) * 1989-02-11 1993-02-09 Orion-Yhtyma Oy Thiadiazines and pharmaceutical compositions thereof as well as method of use
FI973804A7 (fi) * 1997-09-26 1999-03-27 Orion Yhtymae Oy Levosimendaanin oraalisia koostumuksia

Also Published As

Publication number Publication date
FI20000577A0 (fi) 2000-03-13
CZ20022997A3 (cs) 2003-04-16
HK1052008A1 (en) 2003-08-29
HUP0300177A3 (en) 2003-09-29
IL151492A (en) 2007-09-20
AU2001246577B2 (en) 2006-08-31
RS50439B (sr) 2009-12-31
EA005574B1 (ru) 2005-04-28
PL357107A1 (en) 2004-07-12
BG65859B1 (bg) 2010-03-31
HRP20020816A2 (en) 2004-12-31
DE60117131T2 (de) 2006-10-26
EA200200973A1 (ru) 2003-02-27
CN1191241C (zh) 2005-03-02
EE200200520A (et) 2004-04-15
CA2403188A1 (en) 2001-09-20
ATE317388T1 (de) 2006-02-15
NO20024247L (no) 2002-10-25
JP2003527375A (ja) 2003-09-16
EP1265871B1 (en) 2006-02-08
IL151492A0 (en) 2003-04-10
HUP0300177A2 (hu) 2003-07-28
AU4657701A (en) 2001-09-24
NO324172B1 (no) 2007-09-03
NO20024247D0 (no) 2002-09-05
WO2001068611A1 (en) 2001-09-20
BG107175A (bg) 2003-05-30
CN1418196A (zh) 2003-05-14
DK1265871T3 (da) 2006-06-06
US6699868B2 (en) 2004-03-02
EP1265871A1 (en) 2002-12-18
ES2256222T3 (es) 2006-07-16
SI1265871T1 (sl) 2006-06-30
NZ521162A (en) 2003-11-28
YU68502A (sh) 2005-11-28
ZA200206917B (en) 2003-07-30
BR0109136A (pt) 2002-12-24
AR027644A1 (es) 2003-04-09
SK12882002A3 (sk) 2003-06-03
DE60117131D1 (de) 2006-04-20
KR20030001379A (ko) 2003-01-06
SK287163B6 (sk) 2010-02-08
US20030158200A1 (en) 2003-08-21
MXPA02008997A (es) 2003-04-25

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