UA77301C2 - Tetrahydro-naphthalene derivatives - Google Patents

Info

Publication number

UA77301C2

UA77301C2 UA20041210079A UA20041210079A UA77301C2 UA 77301 C2 UA77301 C2 UA 77301C2 UA 20041210079 A UA20041210079 A UA 20041210079A UA 20041210079 A UA20041210079 A UA 20041210079A UA 77301 C2 UA77301 C2 UA 77301C2

Authority

UA

Ukraine

Prior art keywords

still

hydroxy

tetrahydro

urea

naphthalenyl

Prior art date

2002-05-08

Links

• Espacenet
• Global Dossier
• Discuss

• CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical class C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 title abstract 3
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• 208000027866 inflammatory disease Diseases 0.000 claims abstract description 7
• XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 122
• 150000001875 compounds Chemical class 0.000 claims description 116
• 239000004202 carbamide Substances 0.000 claims description 79
• -1 hydroxy, nitro, carboxy, amino Chemical group 0.000 claims description 57
• 229910052739 hydrogen Inorganic materials 0.000 claims description 37
• 239000001257 hydrogen Substances 0.000 claims description 36
• 238000000034 method Methods 0.000 claims description 33
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 33
• 125000000217 alkyl group Chemical group 0.000 claims description 27
• 229910052736 halogen Inorganic materials 0.000 claims description 23
• 238000012360 testing method Methods 0.000 claims description 21
• GYUVMUDBAKAYON-UHFFFAOYSA-N 1-hydroxy-1-(1,2,3,4-tetrahydronaphthalen-1-yl)urea Chemical class C1=CC=C2C(N(O)C(=O)N)CCCC2=C1 GYUVMUDBAKAYON-UHFFFAOYSA-N 0.000 claims description 20
• UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 20
• 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 17
• 150000002431 hydrogen Chemical class 0.000 claims description 16
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• 125000004093 cyano group Chemical group *C#N 0.000 claims description 10
• WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 8
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