AR039983A1 - Derivados de hidroxi tetrahidro-naftalenilurea - Google Patents
Derivados de hidroxi tetrahidro-naftalenilureaInfo
- Publication number
- AR039983A1 AR039983A1 ARP030101614A ARP030101614A AR039983A1 AR 039983 A1 AR039983 A1 AR 039983A1 AR P030101614 A ARP030101614 A AR P030101614A AR P030101614 A ARP030101614 A AR P030101614A AR 039983 A1 AR039983 A1 AR 039983A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- halogen
- amino
- optionally substituted
- tri
- Prior art date
Links
- 229910052736 halogen Inorganic materials 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 2
- 208000002193 Pain Diseases 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- -1 hydroxy, nitro, carboxy, amino Chemical group 0.000 abstract 2
- 208000004296 neuralgia Diseases 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical class C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 abstract 1
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
- GYUVMUDBAKAYON-UHFFFAOYSA-N 1-hydroxy-1-(1,2,3,4-tetrahydronaphthalen-1-yl)urea Chemical class C1=CC=C2C(N(O)C(=O)N)CCCC2=C1 GYUVMUDBAKAYON-UHFFFAOYSA-N 0.000 abstract 1
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 206010021639 Incontinence Diseases 0.000 abstract 1
- 208000028389 Nerve injury Diseases 0.000 abstract 1
- 208000004550 Postoperative Pain Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000005115 alkyl carbamoyl group Chemical group 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000006310 cycloalkyl amino group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000008764 nerve damage Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 201000001119 neuropathy Diseases 0.000 abstract 1
- 230000007823 neuropathy Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 230000002485 urinary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0210512.0A GB0210512D0 (en) | 2002-05-08 | 2002-05-08 | Tetrahydro-napthalene derivatives |
| GBGB0227262.3A GB0227262D0 (en) | 2002-05-08 | 2002-11-21 | Tetrahydro-naphthalene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR039983A1 true AR039983A1 (es) | 2005-03-09 |
Family
ID=9936269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP030101614A AR039983A1 (es) | 2002-05-08 | 2003-05-08 | Derivados de hidroxi tetrahidro-naftalenilurea |
Country Status (13)
| Country | Link |
|---|---|
| KR (1) | KR101000688B1 (fr) |
| AR (1) | AR039983A1 (fr) |
| CU (1) | CU23422B7 (fr) |
| DO (1) | DOP2003000642A (fr) |
| EC (1) | ECSP045413A (fr) |
| GB (2) | GB0210512D0 (fr) |
| GT (1) | GT200300102A (fr) |
| MA (1) | MA30728B1 (fr) |
| MY (1) | MY155011A (fr) |
| PE (1) | PE20040363A1 (fr) |
| PT (1) | PT1506167E (fr) |
| UA (1) | UA77301C2 (fr) |
| ZA (1) | ZA200408993B (fr) |
-
2002
- 2002-05-08 GB GBGB0210512.0A patent/GB0210512D0/en not_active Ceased
- 2002-11-21 GB GBGB0227262.3A patent/GB0227262D0/en not_active Ceased
-
2003
- 2003-04-28 UA UA20041210079A patent/UA77301C2/uk unknown
- 2003-04-28 PT PT03722554T patent/PT1506167E/pt unknown
- 2003-04-28 KR KR1020047017969A patent/KR101000688B1/ko not_active Expired - Fee Related
- 2003-05-05 GT GT200300102A patent/GT200300102A/es unknown
- 2003-05-06 MY MYPI20031696A patent/MY155011A/en unknown
- 2003-05-07 DO DO2003000642A patent/DOP2003000642A/es unknown
- 2003-05-07 PE PE2003000445A patent/PE20040363A1/es not_active Application Discontinuation
- 2003-05-08 AR ARP030101614A patent/AR039983A1/es active IP Right Grant
-
2004
- 2004-11-04 CU CU20040254A patent/CU23422B7/es unknown
- 2004-11-05 MA MA27935A patent/MA30728B1/fr unknown
- 2004-11-05 ZA ZA2004/08993A patent/ZA200408993B/en unknown
- 2004-11-08 EC EC2004005413A patent/ECSP045413A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1506167E (pt) | 2007-12-10 |
| KR101000688B1 (ko) | 2010-12-10 |
| GB0227262D0 (en) | 2002-12-31 |
| KR20040108784A (ko) | 2004-12-24 |
| CU23422B7 (es) | 2009-09-08 |
| MA30728B1 (fr) | 2009-10-01 |
| ECSP045413A (es) | 2005-01-03 |
| DOP2003000642A (es) | 2003-11-15 |
| PE20040363A1 (es) | 2004-07-03 |
| GT200300102A (es) | 2004-03-17 |
| MY155011A (en) | 2015-08-28 |
| GB0210512D0 (en) | 2002-06-19 |
| UA77301C2 (en) | 2006-11-15 |
| ZA200408993B (en) | 2006-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |