UA78183C2 - Composition for in vitro fertilization - Google Patents

Composition for in vitro fertilization Download PDF

Info

Publication number: UA78183C2
Authority: UA; Ukraine
Prior art keywords: less; composition according; composition; better; cholest
Prior art date: 1999-09-16

Application number

UA2002032077A

Other languages

English (en)

Ukrainian (uk)

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-09-16

Filing date

2000-11-09

Publication date

2007-03-15

2000-11-09 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

2007-03-15 Publication of UA78183C2 publication Critical patent/UA78183C2/uk

Links

239000000203 mixture Substances 0.000 title claims description 46
230000004720 fertilization Effects 0.000 title description 2
238000000338 in vitro Methods 0.000 title 1
230000021121 meiosis Effects 0.000 claims abstract description 5
239000000126 substance Substances 0.000 claims abstract description 4
239000000654 additive Substances 0.000 claims description 12
230000000996 additive effect Effects 0.000 claims description 8
108091006905 Human Serum Albumin Proteins 0.000 claims description 6
102000008100 Human Serum Albumin Human genes 0.000 claims description 6
239000007864 aqueous solution Substances 0.000 claims description 5
239000003960 organic solvent Substances 0.000 claims description 5
239000002253 acid Substances 0.000 claims description 2
150000001408 amides Chemical class 0.000 claims description 2
229930182817 methionine Natural products 0.000 claims description 2
238000012876 topography Methods 0.000 claims 1
102000004169 proteins and genes Human genes 0.000 abstract description 2
108090000623 proteins and genes Proteins 0.000 abstract description 2
230000003213 activating effect Effects 0.000 abstract 1
239000008247 solid mixture Substances 0.000 abstract 1
239000000243 solution Substances 0.000 description 32
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 24
210000000287 oocyte Anatomy 0.000 description 23
239000002609 medium Substances 0.000 description 12
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
150000001875 compounds Chemical class 0.000 description 9
239000000047 product Substances 0.000 description 8
238000000034 method Methods 0.000 description 7
241000699670 Mus sp. Species 0.000 description 6
239000003637 basic solution Substances 0.000 description 4
238000001704 evaporation Methods 0.000 description 4
230000008020 evaporation Effects 0.000 description 4
238000002156 mixing Methods 0.000 description 4
239000012736 aqueous medium Substances 0.000 description 3
-1 for example Proteins 0.000 description 3
102000012673 Follicle Stimulating Hormone Human genes 0.000 description 2
108010079345 Follicle Stimulating Hormone Proteins 0.000 description 2
229940028334 follicle stimulating hormone Drugs 0.000 description 2
FDGQSTZJBFJUBT-UHFFFAOYSA-N hypoxanthine Chemical compound O=C1NC=NC2=C1NC=N2 FDGQSTZJBFJUBT-UHFFFAOYSA-N 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
239000002904 solvent Substances 0.000 description 2
238000003756 stirring Methods 0.000 description 2
TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 description 1
108091003079 Bovine Serum Albumin Proteins 0.000 description 1
102000004190 Enzymes Human genes 0.000 description 1
108090000790 Enzymes Proteins 0.000 description 1
JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 description 1
ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 description 1
102000006771 Gonadotropins Human genes 0.000 description 1
108010086677 Gonadotropins Proteins 0.000 description 1
101000979190 Homo sapiens Transcription factor MafB Proteins 0.000 description 1
UGQMRVRMYYASKQ-UHFFFAOYSA-N Hypoxanthine nucleoside Natural products OC1C(O)C(CO)OC1N1C(NC=NC2=O)=C2N=C1 UGQMRVRMYYASKQ-UHFFFAOYSA-N 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 1
108010071390 Serum Albumin Proteins 0.000 description 1
102000007562 Serum Albumin Human genes 0.000 description 1
102100023234 Transcription factor MafB Human genes 0.000 description 1
230000002411 adverse Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
238000007664 blowing Methods 0.000 description 1
229940098773 bovine serum albumin Drugs 0.000 description 1
239000013065 commercial product Substances 0.000 description 1
ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
150000002327 glycerophospholipids Chemical class 0.000 description 1
239000002622 gonadotropin Substances 0.000 description 1
229940094892 gonadotropins Drugs 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
230000035800 maturation Effects 0.000 description 1
210000001672 ovary Anatomy 0.000 description 1
WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 description 1
150000008104 phosphatidylethanolamines Chemical class 0.000 description 1
150000003905 phosphatidylinositols Chemical class 0.000 description 1
210000004508 polar body Anatomy 0.000 description 1
239000011148 porous material Substances 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
239000002342 ribonucleoside Substances 0.000 description 1
230000005070 ripening Effects 0.000 description 1
239000012047 saturated solution Substances 0.000 description 1
238000000926 separation method Methods 0.000 description 1
238000000527 sonication Methods 0.000 description 1
239000011550 stock solution Substances 0.000 description 1
238000011179 visual inspection Methods 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Reproductive Health (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Dermatology (AREA)
Inorganic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Endocrinology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

UA2002032077A 1999-09-16 2000-11-09 Composition for in vitro fertilization UA78183C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199901308		1999-09-16
PCT/DK2000/000500 WO2001019354A2 (fr)	1999-09-16	2000-09-11	Composition pour fecondation in vitro

Publications (1)

Publication Number	Publication Date
UA78183C2 true UA78183C2 (en)	2007-03-15

Family

ID=8103409

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA2002032077A UA78183C2 (en)	1999-09-16	2000-11-09	Composition for in vitro fertilization

Country Status (21)

Country	Link
US (1)	US6844313B1 (fr)
EP (1)	EP1216059B1 (fr)
JP (1)	JP2003509365A (fr)
KR (1)	KR100757909B1 (fr)
CN (1)	CN1222319C (fr)
AT (1)	ATE306942T1 (fr)
AU (1)	AU781994B2 (fr)
BR (1)	BR0014058A (fr)
CA (1)	CA2382908A1 (fr)
CZ (1)	CZ2002591A3 (fr)
DE (1)	DE60023324T2 (fr)
ES (1)	ES2252048T3 (fr)
HU (1)	HUP0202630A3 (fr)
IL (1)	IL148234A0 (fr)
MX (1)	MXPA02002439A (fr)
NO (1)	NO323694B1 (fr)
PL (1)	PL202224B1 (fr)
RU (1)	RU2263516C2 (fr)
UA (1)	UA78183C2 (fr)
WO (1)	WO2001019354A2 (fr)
ZA (1)	ZA200201383B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ20012671A3 (cs) *	1999-02-26	2002-01-16	Novo Nordisk A/S	Způsob in vitro oplodnění s pouľitím kultivačního média obsahujícího sterol aktivující meiosu
CA2382908A1 (fr)	1999-09-16	2001-03-22	Novo Nordisk A/S	Composition pour fecondation in vitro
MXPA02007818A (es) *	2000-02-25	2002-10-23	Schering Ag	Tasa de implantacion mejorada utilizando ff-mas.
US6988613B2 (en)	2001-02-06	2006-01-24	Novo Nordisk A/S	Composition for IVF
EP1245572A1 (fr)	2001-03-26	2002-10-02	Schering Aktiengesellschaft	Composés aminostérols, leur utilisation pour la préparation des médicaments pour la régulation de la méiose et un procédé de leur préparation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4175074A (en)	1976-08-23	1979-11-20	Deshmukh Arvind D	Serum-soluble cholesterol compounds and method for their preparation
US4751219A (en)	1985-02-05	1988-06-14	Nederlandse Centrale Organisatie Voor Toegepast-Natuur-Wetenschappelijk Onderzoek	Synthetic glycolipides, a process for the preparation thereof and several uses for these synthetic glycolipides
WO1990003429A1 (fr) *	1988-09-23	1990-04-05	Cetus Corporation	Micro-emulsions de lipides pour milieux de culture
DE4221880A1 (de)	1992-07-03	1994-01-05	Alfatec Pharma Gmbh	Feste und flüssige Lösungen von schwer wasserlöslichen Arzneistoffen
CA2150803C (fr) *	1992-12-02	2006-01-31	Henry Auer	Hormone de croissance a liberation controlee qui contient des microspheres
US5716777A (en) *	1994-06-23	1998-02-10	Novo Nordisk A/S	Regulation of meiosis using sterols
US6281015B1 (en) *	1994-12-16	2001-08-28	Children's Medical Center Corp.	Localized delivery of factors enhancing survival of transplanted cells
HUP9800731A3 (en) *	1995-03-06	2000-03-28	Novo Nordisk As	Stimulation of meiosis
CA2224866A1 (fr)	1995-06-23	1997-01-09	Novo Nordisk A/S	Composes regulateurs de la meiose
GB9625175D0 (en) *	1996-12-04	1997-01-22	Medi Cult As	Serum-free cell culture media
JP2001506656A (ja) *	1996-12-20	2001-05-22	ノボノルディスクアクティーゼルスカブ	減数分裂調節化合物
TR199902873T2 (xx)	1997-06-04	2000-04-21	Akzo Nobel N.V.	Miyozun mod�lasyonu i�in 17�-aliloksi(tiyo)alkil-androstan t�revleri.
HUP9701554D0 (en)	1997-09-18	1997-11-28	Human Oltoanyagtermeloe Gyogys	Pharmaceutical composition containing plazma proteins
EP1098652A2 (fr)	1998-05-26	2001-05-16	Schering Aktiengesellschaft	Traitement de l'infertilite par des composes stimulant la production d'ampc, seuls ou associes a au moins un compose stimulant la meiose
CZ20012671A3 (cs) *	1999-02-26	2002-01-16	Novo Nordisk A/S	Způsob in vitro oplodnění s pouľitím kultivačního média obsahujícího sterol aktivující meiosu
CA2382908A1 (fr)	1999-09-16	2001-03-22	Novo Nordisk A/S	Composition pour fecondation in vitro

2000
- 2000-09-11 CA CA002382908A patent/CA2382908A1/fr not_active Abandoned
- 2000-09-11 AT AT00958274T patent/ATE306942T1/de not_active IP Right Cessation
- 2000-09-11 BR BR0014058-9A patent/BR0014058A/pt not_active Application Discontinuation
- 2000-09-11 CZ CZ2002591A patent/CZ2002591A3/cs unknown
- 2000-09-11 DE DE60023324T patent/DE60023324T2/de not_active Expired - Fee Related
- 2000-09-11 PL PL353968A patent/PL202224B1/pl not_active IP Right Cessation
- 2000-09-11 ES ES00958274T patent/ES2252048T3/es not_active Expired - Lifetime
- 2000-09-11 AU AU69850/00A patent/AU781994B2/en not_active Ceased
- 2000-09-11 HU HU0202630A patent/HUP0202630A3/hu unknown
- 2000-09-11 IL IL14823400A patent/IL148234A0/xx unknown
- 2000-09-11 WO PCT/DK2000/000500 patent/WO2001019354A2/fr not_active Ceased
- 2000-09-11 KR KR1020027003526A patent/KR100757909B1/ko not_active Expired - Fee Related
- 2000-09-11 EP EP00958274A patent/EP1216059B1/fr not_active Expired - Lifetime
- 2000-09-11 MX MXPA02002439A patent/MXPA02002439A/es active IP Right Grant
- 2000-09-11 JP JP2001522989A patent/JP2003509365A/ja active Pending
- 2000-09-11 CN CNB008128820A patent/CN1222319C/zh not_active Expired - Fee Related
- 2000-09-11 RU RU2002109794/15A patent/RU2263516C2/ru not_active IP Right Cessation
- 2000-09-14 US US09/661,696 patent/US6844313B1/en not_active Expired - Fee Related
- 2000-11-09 UA UA2002032077A patent/UA78183C2/uk unknown
2002
- 2002-02-19 ZA ZA200201383A patent/ZA200201383B/en unknown
- 2002-03-15 NO NO20021309A patent/NO323694B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2382908A1 (fr)	2001-03-22
HUP0202630A2 (hu)	2002-12-28
IL148234A0 (en)	2002-09-12
BR0014058A (pt)	2004-03-30
ATE306942T1 (de)	2005-11-15
NO323694B1 (no)	2007-06-25
KR20020032593A (ko)	2002-05-03
DE60023324T2 (de)	2006-07-20
EP1216059B1 (fr)	2005-10-19
CZ2002591A3 (cs)	2002-08-14
WO2001019354A2 (fr)	2001-03-22
DE60023324D1 (de)	2005-11-24
AU781994B2 (en)	2005-06-23
NO20021309L (no)	2002-03-15
US6844313B1 (en)	2005-01-18
ZA200201383B (en)	2002-11-27
MXPA02002439A (es)	2002-07-30
PL353968A1 (en)	2003-12-15
KR100757909B1 (ko)	2007-09-11
HUP0202630A3 (en)	2004-06-28
EP1216059A2 (fr)	2002-06-26
JP2003509365A (ja)	2003-03-11
PL202224B1 (pl)	2009-06-30
ES2252048T3 (es)	2006-05-16
CN1222319C (zh)	2005-10-12
AU6985000A (en)	2001-04-17
WO2001019354A3 (fr)	2001-06-14
RU2263516C2 (ru)	2005-11-10
NO20021309D0 (no)	2002-03-15
CN1373675A (zh)	2002-10-09

Publication	Publication Date	Title
EP0509761B1 (fr)	1996-09-11	Composition transdermique à base de sélégiline
Cameron et al.	1994	In vitro development of the sea urchin male pronucleus
UA78183C2 (en)	2007-03-15	Composition for in vitro fertilization
EP2242496A1 (fr)	2010-10-27	Procédés de maturation in vitro de follicules ovariens
Suzuki et al.	1965	In vitro fertilization of rabbit ova in tubal fluid
Akki et al.	2020	Formulation and evaluation of mupirocin nimosomal gel for topical drug delivery system
KR101263963B1 (ko)	2013-05-13	항바이러스 및 면역자극 해산 어류 오일 조성물
Petr et al.	2005	Nitric oxide-dependent activation of pig oocytes: role of calcium
TWI281404B (en)	2007-05-21	Composition for IVF
RU2296571C1 (ru)	2007-04-10	Ранозаживляющий состав и способ его получения
US6988613B2 (en)	2006-01-24	Composition for IVF
ES2301627T3 (es)	2008-07-01	Envase con bajo contenido de oxigeno que contiene ff-mas.
JP2004269534A (ja)	2004-09-30	駆虫性レジネートおよびその調製法
Roberts et al.	1954	The appearance of starch grains of potato tubers of plants grown under constant light and temperature conditions
Brinster	1964	Studies on the development of mouse embryos in vitro.
Sakkas et al.	1991	Formulation of a complex serum-free medium (CSM) for use in the co-culture of mouse embryos with cells of the female reproductive tract
RU2236457C2 (ru)	2004-09-20	Способ получения питательной среды "лимфокар" для культивирования лимфоцитов периферической крови человека и животных
Makler et al.	1980	The effect of copper on spermatozoal motility and viability evaluated objectively with the aid of the multiple-exposure photography method
Lubzens et al.	1981	Active vitellogenesis in precocene-treated Locusta migratoria
Richter	1979	A STUDY OF THE REGULATION OF MAMMALIAN OOCYTE MATURATION.
Palmieri	1991	Platelet-derived growth factor in early mouse embryogenesis
Kayser	2001	The effects of uterine-spermatozoa co-culture on equine uterine protein synthesis and stallion spermatozoal maturation
JPS6030282B2 (ja)	1985-07-16	殺カビおよび殺ダニ調合物
JPS6287502A (ja)	1987-04-22	安定化された殺菌剤
UA134981U (uk)	2019-06-10	Спосіб отримання ліпосомальної форми куркуміну