UA80976C2 - Processes and materials for production of d-lactic acid in yeast - Google Patents

Processes and materials for production of d-lactic acid in yeast Download PDF

Info

Publication number
UA80976C2
UA80976C2 UA20041210933A UA20041210933A UA80976C2 UA 80976 C2 UA80976 C2 UA 80976C2 UA 20041210933 A UA20041210933 A UA 20041210933A UA 20041210933 A UA20041210933 A UA 20041210933A UA 80976 C2 UA80976 C2 UA 80976C2
Authority
UA
Ukraine
Prior art keywords
gene
lactic acid
promoter
cell according
terminator
Prior art date
Application number
UA20041210933A
Other languages
English (en)
Ukrainian (uk)
Inventor
Steisey Olson
Original Assignee
Cargill Dow Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Dow Llc filed Critical Cargill Dow Llc
Publication of UA80976C2 publication Critical patent/UA80976C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
UA20041210933A 2002-05-30 2003-05-30 Processes and materials for production of d-lactic acid in yeast UA80976C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38433302P 2002-05-30 2002-05-30
PCT/US2003/017310 WO2003102201A2 (en) 2002-05-30 2003-05-30 Methods and materials for the production of d-lactic acid in yeast

Publications (1)

Publication Number Publication Date
UA80976C2 true UA80976C2 (en) 2007-11-26

Family

ID=29712012

Family Applications (2)

Application Number Title Priority Date Filing Date
UA20041210933A UA80976C2 (en) 2002-05-30 2003-05-30 Processes and materials for production of d-lactic acid in yeast
UA20041210932A UA88437C2 (ru) 2002-05-30 2003-05-30 Процесс ферментации при участии генетически модифицированых дрожжей и способ осуществления ферментации

Family Applications After (1)

Application Number Title Priority Date Filing Date
UA20041210932A UA88437C2 (ru) 2002-05-30 2003-05-30 Процесс ферментации при участии генетически модифицированых дрожжей и способ осуществления ферментации

Country Status (15)

Country Link
US (7) US20040029256A1 (de)
EP (4) EP2878675B1 (de)
JP (4) JP2005528112A (de)
CN (4) CN100335626C (de)
AT (1) ATE367436T1 (de)
AU (4) AU2003243366B2 (de)
BR (4) BR0311452A (de)
CA (3) CA2487296A1 (de)
DE (1) DE60315028T2 (de)
DK (1) DK2878675T3 (de)
ES (3) ES2642928T3 (de)
PT (1) PT1513923E (de)
UA (2) UA80976C2 (de)
WO (3) WO2003102200A2 (de)
ZA (3) ZA200409529B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2553563C2 (ru) * 2009-06-03 2015-06-20 Торэй Индастриз, Инк. Полипептид, обладающий активностью d-лактатдегидрогеназы, полинуклеотид, кодирующий этот полипептид, и способ получения d-молочной кислоты

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US20070031950A1 (en) * 1998-09-11 2007-02-08 Winkler Aaron A Production of D-lactic acid with yeast
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
ATE367436T1 (de) 2002-05-30 2007-08-15 Natureworks Llc Verfahren und materialien zur produktion von d- milchsäure in hefe
JP4711955B2 (ja) 2003-05-02 2011-06-29 ネイチャーワークス・エル・エル・シー 遺伝子組換え酵母及び遺伝子組換え酵母を用いた発酵方法
JP4460876B2 (ja) * 2003-11-07 2010-05-12 株式会社豊田中央研究所 有機酸存在下におけるプロモーター及びその利用
US20050112737A1 (en) * 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
JP4806904B2 (ja) * 2004-07-09 2011-11-02 トヨタ自動車株式会社 乳酸生産方法
JP2006296377A (ja) * 2005-04-25 2006-11-02 Toyota Central Res & Dev Lab Inc 有機酸生産用形質転換体
JP2008545429A (ja) * 2005-06-02 2008-12-18 カーギル インコーポレイテッド 遺伝子操作されたIssatchenkiaorientalis種又はその近隣種の酵母及びこの酵母を用いた発酵方法
ES2401339T3 (es) 2005-08-10 2013-04-18 University Of Florida Research Foundation, Inc. Materiales y métodos para producción eficiente de ácido láctico
JP4692173B2 (ja) * 2005-09-13 2011-06-01 東レ株式会社 D−乳酸デヒドロゲナーゼ活性を有するポリペプチド、これをコードする遺伝子およびd−乳酸の製造方法
US7718405B2 (en) * 2005-09-19 2010-05-18 American Air Liquide, Inc. Use of pure oxygen in viscous fermentation processes
CA2623751A1 (en) 2005-09-22 2007-04-05 Tate & Lyle Ingredients Americas, Inc. Improved strains for the production of organic acids
EP1975232A4 (de) * 2005-10-14 2009-07-29 Toray Industries Hefe und verfahren zur herstellung von l-milchsäure
JP5121070B2 (ja) 2005-11-23 2013-01-16 ネイチャーワークス・エル・エル・シー L−又はd−ラクタート:フェリチトクロームc酸化還元酵素遺伝子が機能しない乳酸産生酵母
WO2007085443A2 (en) * 2006-01-24 2007-08-02 Purac Biochem Bv Genetic modification of homolactic thermophilic bacilli
ES2620770T3 (es) 2006-03-13 2017-06-29 Cargill, Incorporated Proceso de fermentación que emplea células de levadura que tienen una ruta alterada desde dihidroxiacetona fosfato hasta glicerol
JP5320692B2 (ja) * 2006-06-28 2013-10-23 東レ株式会社 酵母及びl−乳酸の製造方法
US20080064076A1 (en) * 2006-09-11 2008-03-13 Saucedo Victor M Dissolved Oxygen Profile to Increase Fermentation Productivity and Economics
JP5141126B2 (ja) * 2006-09-26 2013-02-13 東レ株式会社 連続発酵によるd−乳酸の製造方法
WO2008052596A1 (en) * 2006-10-31 2008-05-08 Metabolic Explorer Process for the biological production of n-butanol with high yield
JP2010508013A (ja) * 2006-10-31 2010-03-18 メタボリック エクスプローラー グリセロールから1,3−プロパンジオールを高収量で生物学的に製造する方法
CN101743310A (zh) 2006-12-07 2010-06-16 麻省理工学院 全局转录机器的改造
JP5130826B2 (ja) * 2007-03-28 2013-01-30 東レ株式会社 連続発酵による乳酸の製造方法
JP2008283917A (ja) * 2007-05-18 2008-11-27 Toray Ind Inc 乳酸の製造方法
AU2008305655B2 (en) 2007-09-20 2013-10-31 Amyris, Inc. Production of isoprenoids
BRPI0818979A2 (pt) * 2007-12-07 2014-10-14 Toray Industries "cassete de expressão de lactato desidrogenase, cepa de levedura transformante e método de produzir ácido láctico"
US8455239B2 (en) 2007-12-23 2013-06-04 Gevo, Inc. Yeast organism producing isobutanol at a high yield
CN101952448A (zh) * 2007-12-23 2011-01-19 格沃股份有限公司 高产率产生异丁醇的酵母生物
CN101959568A (zh) 2007-12-27 2011-01-26 格沃股份有限公司 从稀水溶液回收高级醇
WO2009099044A1 (ja) * 2008-02-04 2009-08-13 Toray Industries, Inc. 連続発酵による乳酸の製造方法
US20090235951A1 (en) * 2008-03-18 2009-09-24 Legrande W E Environmentally Responsible Dental Floss and Packaging
JP4963488B2 (ja) * 2008-04-23 2012-06-27 トヨタ自動車株式会社 変異体酵母及びこれを用いた物質生産方法
US9012187B2 (en) * 2008-07-08 2015-04-21 Dsm Ip Assets B.V. Dicarboxylic acid production by fermentation at low pH
CA2738452C (en) 2008-10-03 2016-06-21 Metabolic Explorer Method for purifying an alcohol from a fermentation broth using a falling film, a wiped film, a thin film or a short path evaporator
EP2390342A1 (de) * 2009-01-23 2011-11-30 Agribioindustry Inc. Verfahren zur erzeugung von d-milchsäure und verfahren zur erhöhung der optischen reinheit von d-milchsäure oder des ertrags von d-milchsäure hinsichtlich des zuckergehalts in milchsäure
EP2446045A4 (de) * 2009-06-26 2017-04-19 GEVO, Inc. Wiedergewinnung von höheren alkoholen aus gelösten wässrigen lösungen
MX2012000150A (es) 2009-07-02 2012-04-11 Verdezyne Inc Metodos biologicos para preparar acido adipico.
JPWO2011013721A1 (ja) * 2009-07-28 2013-01-10 三井化学株式会社 乳酸製造方法
BR112012002153A2 (pt) 2009-07-30 2015-09-15 Metabolic Explorer Sa metilglioxal sintase mutante (mgs) para a produção de material bioquímico por fermentação
PL2470667T3 (pl) 2009-08-27 2018-04-30 Dsm Ip Assets B.V. Sposób wytwarzania kwasu dikarboksylowego na drodze fermentacji
EP2485995A4 (de) * 2009-10-06 2015-12-02 Gevo Inc Integriertes verfahren zur selektiven umwandlung von erneuerbarem isobutanol in p-xylen
CA2794817C (en) 2010-04-21 2019-03-12 Dsm Ip Assets B.V. Cell suitable for fermentation of a mixed sugar composition
US9012190B2 (en) 2011-06-15 2015-04-21 Butamax Advanced Biofuels Llc Use of thiamine and nicotine adenine dinucleotide for butanol production
CA2807102C (en) 2010-07-31 2018-08-21 Myriant Corporation Improved fermentation process for the production of organic acids
CA2813513A1 (en) 2010-10-13 2012-04-19 Dsm Ip Assets B.V. Polypeptides with permease activity
CA2885934C (en) 2010-11-22 2018-05-01 Cargill, Incorporated Compositions and methods for increased ethanol titer from biomass
CN103502432A (zh) 2010-11-22 2014-01-08 诺维信股份有限公司 用于生产3-羟基丙酸的组合物和方法
EP2668281A4 (de) 2011-01-25 2015-08-26 Cargill Inc Zusammensetzungen und verfahren zur succinatherstellung
SG193589A1 (en) * 2011-03-29 2013-10-30 Nestec Sa Natural derivative of the lactobacilus johnsonii strain cncm i-1225, deficient in d-lactic acid production and with a further improved immune profile
US9512495B2 (en) 2011-04-07 2016-12-06 Virdia, Inc. Lignocellulose conversion processes and products
DK2697252T3 (en) 2011-04-11 2016-12-12 Cargill Inc Configurations and methods for increased ethanol production from biomass
CA2833312A1 (en) 2011-04-22 2012-10-26 Dsm Ip Assets B.V. Yeast cell capable of converting sugars including arabinose and xylose
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
CN102285664B (zh) * 2011-05-27 2013-06-19 广西崇左市湘桂糖业有限公司 模拟移动床分离l-乳酸和d-乳酸专用分子筛及其制备方法
CN103717746B (zh) * 2011-08-11 2016-05-18 三井化学株式会社 通过连续培养制造异丙醇的方法
EP2807262A4 (de) * 2012-01-25 2015-12-30 Bioamber Internat S A R L Verfahren zur succinatherstellung
CN104093846B (zh) * 2012-02-22 2017-03-22 诺维信公司 先进的发酵控制
FR2988733B1 (fr) * 2012-03-27 2016-02-05 Carbios Microorganisme recombinant
KR101438882B1 (ko) * 2012-04-24 2014-09-05 씨제이제일제당 (주) 신규한 d형 젖산 생산균주
US9493851B2 (en) 2012-05-03 2016-11-15 Virdia, Inc. Methods for treating lignocellulosic materials
GB2518547B (en) 2012-05-03 2015-10-07 Virdia Ltd Method for the preparation of high purity lignin
WO2014003439A1 (ko) * 2012-06-26 2014-01-03 한국생명공학연구원 에탄올 생산 경로가 봉쇄된 클루이베로마이세스 막시아누스 균주 및 이의 용도
EP3901248A1 (de) 2012-07-25 2021-10-27 Cargill, Incorporated Hefezellen mit reduktivem tca-weg von pyruvat zu succinat und überexpression eines exogenen nad(p)+-transhydrogenase-enzyms
EP2895593B1 (de) * 2012-09-14 2019-12-11 PTT Global Chemical Public Company Limited Herstellung organischer säuren durch fermentation bei niedrigem ph-wert
PL2909305T3 (pl) 2012-10-16 2019-06-28 Dsm Ip Assets B.V. Komórki o ulepszonej konwersji pentozy
KR20150082241A (ko) 2012-11-07 2015-07-15 디에스엠 아이피 어셋츠 비.브이. pH 제어된 효모 증식
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
EP2925873B1 (de) 2012-11-30 2017-07-12 Novozymes, Inc. Herstellung von 3-hydroxypropionsäure mittels rekombinanter hefen
ES2757913T3 (es) 2013-06-18 2020-04-30 Calysta Inc Composiciones y métodos para la producción biológica de lactato a partir de compuestos de C1 mediante el uso de transformantes de deshidrogenasa láctica
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
US9845484B2 (en) 2013-07-31 2017-12-19 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
BR112016016539A2 (pt) 2014-01-16 2018-01-23 Calysta Inc micro-organismos recombinantes enriquecidos com carboidratos
KR20150096019A (ko) * 2014-02-13 2015-08-24 삼성전자주식회사 유전자 조작 효율이 향상된 효모 세포 및 그의 용도
US9593350B2 (en) 2014-02-14 2017-03-14 Samsung Electronics Co., Ltd. Lactate dehydrogenase mutant, polynucleotide coding for the mutant, yeast cell including the polynucleotide, method of preparing the mutant, and method of producing the lactate using the same
JP6183263B2 (ja) * 2014-03-28 2017-08-23 王子ホールディングス株式会社 D−乳酸の精製のための工程が改良されたd−乳酸の製造方法
ES2924896T3 (es) 2014-05-16 2022-10-11 Carbios Procedimiento para reciclar artículos de plástico mixto con PET
WO2016012429A1 (en) 2014-07-24 2016-01-28 Dsm Ip Assets B.V. Yeast cell with improved pentose transport
KR102245298B1 (ko) 2014-09-05 2021-04-27 삼성전자주식회사 증가된 edc 활성을 갖고 락테이트 생산능을 갖는 유전적으로 조작된 효모 세포, 그를 제조하는 방법, 그를 제조하는 방법, 및 그를 사용하여 락테이트를 생산하는 방법
US10214754B2 (en) 2014-10-10 2019-02-26 Jmtc Enzyme Corporation Transformant and its production process, and method for producing lactic acid
EP3778883A1 (de) 2014-10-21 2021-02-17 Carbios Polypeptid mit polyesterabbauender aktivität und verwendungen davon
WO2016081902A1 (en) 2014-11-20 2016-05-26 Full Cycle Bioplastics Inc. Producing polyhydroxyalkanoate copolymers from organic waste products
WO2016084963A1 (ja) * 2014-11-28 2016-06-02 味の素株式会社 イソプレノイド化合物の製造方法
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
US10626242B2 (en) 2014-12-19 2020-04-21 Carbios Plastic compound and preparation process
SE538899C2 (en) 2015-02-03 2017-01-31 Stora Enso Oyj Method for treating lignocellulosic materials
EP3262161B1 (de) 2015-02-27 2021-06-30 Novozymes A/S Mutante wirtszellen zur herstellung von 3-hydroxypropionsäure
CN107532153A (zh) 2015-03-13 2018-01-02 卡比奥斯公司 具有聚酯降解活性的新多肽及其用途
US20180179499A1 (en) 2015-06-04 2018-06-28 Bioamber Inc. Biobased production of functionalized alpha-substituted acrylates and c4-dicarboxylates
CA2987842C (en) 2015-06-12 2024-01-02 Carbios Biodegradable polyester composition and uses thereof
WO2017035270A1 (en) 2015-08-24 2017-03-02 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
EP3394264A1 (de) 2015-12-21 2018-10-31 Carbios Polymilchsäure produzierende rekombinante hefezellen und verwendungen davon
PL3458508T3 (pl) 2016-05-19 2026-02-23 Carbios Sposób degradowania produktów z tworzyw sztucznych
US10787649B2 (en) 2016-07-13 2020-09-29 Dsm Ip Assets B.V. Malate dehyrogenases
WO2018144701A2 (en) 2017-02-02 2018-08-09 Cargill Incorporated Genetically modified cells that produce c6-c10 fatty acid derivatives
EP3668306A4 (de) 2017-08-17 2021-06-09 Cargill, Incorporated Genetisch modifizierte haploidissatchenkia orientalis
WO2019159011A2 (en) * 2018-02-16 2019-08-22 Ptt Global Chemical Public Company Limited Microorganisms and processes for lactic acid production
US12338428B2 (en) 2018-03-30 2025-06-24 Inv Nylon Chemicals Americas, Llc Materials and methods for managing aerobic gas fermentation
US12065636B2 (en) 2018-03-30 2024-08-20 Inv Nylon Chemicals Americas, Llc High hydrogen utilization and gas recycle
KR102140596B1 (ko) 2018-04-17 2020-08-04 에스케이이노베이션 주식회사 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법
KR102140597B1 (ko) 2018-04-17 2020-08-03 에스케이이노베이션 주식회사 에탄올 생산 경로가 억제된 내산성 효모 및 이를 이용한 젖산의 제조방법
WO2019213033A1 (en) 2018-05-02 2019-11-07 Invista North America S.A.R.L. Materials and methods for maximizing biosynthesis through alteration of pyruvate-acetyl-coa-tca balance in species of the genera ralstonia and cupriavidus and organisms related thereto
US11702680B2 (en) 2018-05-02 2023-07-18 Inv Nylon Chemicals Americas, Llc Materials and methods for controlling PHA biosynthesis in PHA-generating species of the genera Ralstonia or Cupriavidus and organisms related thereto
TWI719317B (zh) * 2018-06-13 2021-02-21 遠東新世紀股份有限公司 用於生產乳酸的方法
CN109097293B (zh) * 2018-07-13 2021-10-26 广东利世康低碳科技有限公司 一种能降解利用餐厨废弃物生成乳酸的基因重组毕赤酵母
KR102736070B1 (ko) 2018-10-08 2024-12-02 에스케이이노베이션 주식회사 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
US20210403928A1 (en) 2018-11-30 2021-12-30 Utilization Of Carbon Dioxide Institute Co., Ltd. Lactic Acid-Producing Hydrogenophilus Bacterium Transformant
EP4012020A4 (de) 2019-08-09 2022-08-17 Utilization of Carbon Dioxide Institute Co.,Ltd. Milchsäure-produzierendes transgenes hydrogenophilus-bakterium
WO2021034276A2 (en) * 2019-08-19 2021-02-25 Ptt Global Chemical Public Company Limited Yeast having improvement of lactic acid tolerance and use thereof
TWI730383B (zh) * 2019-08-21 2021-06-11 遠東新世紀股份有限公司 重組型假絲酵母菌菌株及其製備方法與用途
KR20210041903A (ko) 2019-10-08 2021-04-16 에스케이이노베이션 주식회사 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210128742A (ko) 2020-04-17 2021-10-27 에스케이이노베이션 주식회사 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210158676A (ko) 2020-06-24 2021-12-31 에스케이이노베이션 주식회사 젖산 생산능이 증가된 재조합 내산성 효모
RU2752896C1 (ru) * 2020-12-04 2021-08-11 Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" - ГосНИИгенетика) Штамм дрожжей Schizosaccharomyces pombe, продуцирующий L-молочную кислоту, содержащий в составе хромосомы гены трех различных гетерологичных лактатдегидрогеназ
KR102287114B1 (ko) * 2021-01-25 2021-08-06 씨제이제일제당 주식회사 신규한 사이토신 퍼미에이즈 변이체 및 이를 이용한 l-트립토판 생산 방법
WO2022241027A1 (en) * 2021-05-13 2022-11-17 Lygos, Inc. Recombinant host cells and methods for producing l-lactic acid
CN113430127B (zh) * 2021-07-07 2024-01-12 江南大学 一种产l-乳酸的重组菌及其应用
CN118256415A (zh) * 2021-09-29 2024-06-28 上海肆芃科技有限公司 生产聚乳酸的基因工程菌株及生产聚乳酸的方法
US12049660B2 (en) 2021-11-03 2024-07-30 Wisconsin Alumni Research Foundation Gene duplications for crabtree-warburg-like aerobic xylose fermentation

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3384553A (en) * 1965-04-08 1968-05-21 Ceskoslovenska Akademie Ved Method and equipment for aerobic fermentation on liquid culture mediums
IL39710A (en) 1972-06-19 1975-04-25 Imi Inst For Res & Dev Recovery of acids from aqueous solutions by solvent extraction
US4064015A (en) * 1975-05-12 1977-12-20 New Brunswick Scientific Co., Inc. Control of biosynthesis in submerged culture
US4771001A (en) 1986-03-27 1988-09-13 Neurex Corp. Production of lactic acid by continuous fermentation using an inexpensive raw material and a simplified method of lactic acid purification
US5210296A (en) 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
US5132456A (en) 1991-05-07 1992-07-21 The Regents Of The University Of California Sorption of carboxylic acid from carboxylic salt solutions at PHS close to or above the pKa of the acid, with regeneration with an aqueous solution of ammonia or low-molecular-weight alkylamine
JP3012377B2 (ja) * 1991-10-11 2000-02-21 名糖産業株式会社 低耐熱性プロテアーゼとその関連物及びその生産法
US5247059A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for the manufacture of a purified lactide from esters of lactic acid
US5142023A (en) * 1992-01-24 1992-08-25 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5420304A (en) 1992-03-19 1995-05-30 Biopak Technology, Ltd. Method to produce cyclic esters
FR2693463B1 (fr) * 1992-07-08 1994-09-02 Rhone Poulenc Rorer Sa Promoteur de levure et son utilisation.
US5338822A (en) 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
IL109003A (en) 1994-03-16 1999-09-22 Yissum Res Dev Co Process and extractant composition for extracting water-soluble carboxylic and mineral acids
JPH08173170A (ja) * 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
DK0875579T3 (da) 1997-05-03 2007-10-22 Nestle Sa Fremstilling af L(+)-laktat
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US6229046B1 (en) * 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
US6046002A (en) * 1998-01-05 2000-04-04 The Board Of Trustees Of The Leland Stanford Junior University Highly parallel and sensitive method for identifying drugs and drug targets
WO2000029604A1 (en) * 1998-11-18 2000-05-25 The University Of Akron Production of biological materials by simultaneous aerobic and anaerobic respiration
EP1183385B1 (de) 1999-05-21 2006-07-19 Cargill Dow LLC Methoden und materialien zur synthese von organischen produkten
US6268189B1 (en) * 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
JP2002136293A (ja) * 2000-08-23 2002-05-14 Toray Ind Inc 微生物およびd−乳酸の製造方法
DK1332222T3 (da) * 2000-11-03 2009-07-06 Genentech Inc Stofskifteændringer i fermenteringer der udtrykker rekombinante proteiner
CN1955299A (zh) 2000-11-22 2007-05-02 内特尔沃克公司 合成有机产物的方法和材料
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
KR100426990B1 (ko) * 2001-06-27 2004-04-13 삼성전자주식회사 외부의 코드에 따라 프로그래머블하게 기준 전압을 발생시키는 기준 전압 발생 회로
EP1484407B1 (de) * 2002-03-11 2011-10-26 Toyota Jidosha Kabushiki Kaisha Verfahren zur steuerung der ethanolproduktion und massenproduktion von milchsäure und transformant dafür
ATE367436T1 (de) 2002-05-30 2007-08-15 Natureworks Llc Verfahren und materialien zur produktion von d- milchsäure in hefe
JP4395132B2 (ja) * 2003-05-22 2010-01-06 株式会社豊田中央研究所 D−乳酸脱水素酵素活性を有するタンパク質をコードするdna及びその利用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2553563C2 (ru) * 2009-06-03 2015-06-20 Торэй Индастриз, Инк. Полипептид, обладающий активностью d-лактатдегидрогеназы, полинуклеотид, кодирующий этот полипептид, и способ получения d-молочной кислоты

Also Published As

Publication number Publication date
ES2290466T3 (es) 2008-02-16
WO2003102200A3 (en) 2004-11-04
AU2003243366B2 (en) 2008-01-24
JP2005528111A (ja) 2005-09-22
EP1513939B1 (de) 2014-12-31
US7939298B2 (en) 2011-05-10
JP2005528106A (ja) 2005-09-22
BRPI0311517A2 (pt) 2016-06-28
US20100137551A1 (en) 2010-06-03
EP2878675B1 (de) 2017-07-19
ZA200409531B (en) 2005-11-23
AU2003240481B8 (en) 2008-03-20
DE60315028T2 (de) 2008-04-10
CA2487116A1 (en) 2003-12-11
EP2878675A1 (de) 2015-06-03
PT1513923E (pt) 2007-10-24
UA88437C2 (ru) 2009-10-26
ES2529254T3 (es) 2015-02-18
AU2003251381A1 (en) 2003-12-19
CA2487296A1 (en) 2003-12-11
CN1735683B (zh) 2010-05-26
CA2487116C (en) 2012-02-21
US20140377794A1 (en) 2014-12-25
ES2642928T3 (es) 2017-11-20
ZA200409530B (en) 2005-05-31
US20040043444A1 (en) 2004-03-04
US20070148748A1 (en) 2007-06-28
AU2003243366A1 (en) 2003-12-19
US20040029256A1 (en) 2004-02-12
BR0311452A (pt) 2005-03-29
CA2488196A1 (en) 2003-12-11
WO2003102152A3 (en) 2004-02-12
ATE367436T1 (de) 2007-08-15
US8828707B2 (en) 2014-09-09
EP1513940A2 (de) 2005-03-16
BR0311453A (pt) 2005-03-29
CN1735691A (zh) 2006-02-15
EP1513940A4 (de) 2006-10-25
AU2008202963A1 (en) 2008-07-31
JP2009000124A (ja) 2009-01-08
EP1513923A2 (de) 2005-03-16
EP1513939A4 (de) 2012-08-01
JP4318638B2 (ja) 2009-08-26
ZA200409529B (en) 2005-06-23
CN1688703A (zh) 2005-10-26
CN1735683A (zh) 2006-02-15
US20030228671A1 (en) 2003-12-11
BRPI0311517B1 (pt) 2017-06-27
DK2878675T3 (en) 2017-10-23
CN100335626C (zh) 2007-09-05
WO2003102201A3 (en) 2004-03-18
JP2005528112A (ja) 2005-09-22
WO2003102200A2 (en) 2003-12-11
WO2003102201A2 (en) 2003-12-11
AU2003251381B2 (en) 2008-04-03
US7534597B2 (en) 2009-05-19
EP1513923A4 (de) 2006-05-10
CN1735691B (zh) 2010-05-26
US9428776B2 (en) 2016-08-30
US7232664B2 (en) 2007-06-19
WO2003102152A2 (en) 2003-12-11
AU2003240481A1 (en) 2003-12-19
EP1513923B1 (de) 2007-07-18
US20110229873A1 (en) 2011-09-22
CN101157930A (zh) 2008-04-09
DE60315028D1 (de) 2007-08-30
AU2003240481B2 (en) 2008-01-10
EP1513939A2 (de) 2005-03-16

Similar Documents

Publication Publication Date Title
CN109402158B (zh) 一种产岩藻糖基乳糖的重组表达质粒载体、代谢工程菌及生产方法
US12203105B2 (en) Engineered strain for producing allulose and derivatives thereof, method for construction therefor and use thereof
KR101511639B1 (ko) 재조합 미생물 및 이의 사용 방법
EP1513923B1 (de) Verfahren und materialien zur produktion von d-milchsäure in hefe
EA025990B1 (ru) Полипептиды с оксидоредуктазной активностью и их применение
CN112126615B (zh) 一种产丁酸的枯草芽孢杆菌及其构建方法和应用
KR102345898B1 (ko) 글루코오스 투과 효소 라이브러리를 생성하는 방법 및 이의 용도
CN108676766B (zh) 基因修饰的应用及其获得的菌株
CN110382684A (zh) 产生木糖醇的梅奇酵母种
CN107746815A (zh) 生产13r‑泪柏醚的重组酿酒酵母菌及其构建方法
CN107223152B (zh) 具有改变的一氧化碳脱氢酶(codh)活性的遗传工程细菌
CN116064345A (zh) 高效生产岩藻糖基乳糖的无抗基因工程菌及其应用
KR102793833B1 (ko) 푸코오스 전이효소를 발현하는 재조합 미생물 및 이를 이용한 2’-푸코실락토오스 제조방법
EP4263851A1 (de) Modifizierte ss-1,3-n-acetylglucosaminyltransferase-polypeptide
US20250283124A1 (en) Polyhydroxyalkanoate-producing bacteria and methods for making and using them
KR102320074B1 (ko) 재조합 미생물의 생산 방법
KR102683624B1 (ko) 기능적 dna 서열의 안정화된 카피 수를 갖는 미생물 및 관련 방법
CN110468091B (zh) 微生物及其用途
KR102855858B1 (ko) 메발론산을 생산하는 재조합 미생물 및 이를 이용한 메발론산의 생산 방법
US20250313867A1 (en) Recombinant microorganism with controlled ability to produce polyols or exopolymers
CN107299074B (zh) 甲酸脱氢酶工程菌株的构建方法及应用
CN120025952A (zh) 生产络塞维的基因工程菌和其应用
CN113249281B (zh) 一种利用乙醇生产间苯三酚的重组菌及其构建方法与应用
KR102166288B1 (ko) D-글루타메이트 영양요구성 대장균 및 이를 이용한 목적 물질 생산 방법
CN115322998A (zh) 一种人工转录器件库的构建方法及应用