UA81111C2 - Use of a microglia inhibitor for the production of a pharmaceutical agent that inhibits immune reactions mediated by interleukin 12 (il 12) and interferon-? (variants) - Google Patents

Use of a microglia inhibitor for the production of a pharmaceutical agent that inhibits immune reactions mediated by interleukin 12 (il 12) and interferon-? (variants) Download PDF

Info

Publication number: UA81111C2
Authority: UA; Ukraine
Prior art keywords: group; ring; atom; residues; alkyl
Prior art date: 2002-02-15

Application number

UA20040907401A

Other languages

English (en)

Ukrainian (uk)

Inventor

Torsten Blume

Wolfgang Halfbrodt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-02-15

Filing date

2003-01-17

Publication date

2007-12-10

2003-01-17 Application filed filed Critical

2007-12-10 Publication of UA81111C2 publication Critical patent/UA81111C2/uk

Links

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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Endocrinology (AREA)
Obesity (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

UA20040907401A 2002-02-15 2003-01-17 Use of a microglia inhibitor for the production of a pharmaceutical agent that inhibits immune reactions mediated by interleukin 12 (il 12) and interferon-? (variants) UA81111C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10207843A DE10207843A1 (de)	2002-02-15	2002-02-15	Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen
PCT/EP2003/000467 WO2003068225A1 (de)	2002-02-15	2003-01-17	Mikroglia-inhibitoren zur unterbrechung von interleukin 12 und ifn-gamma vermittelten immunreaktionen

Publications (1)

Publication Number	Publication Date
UA81111C2 true UA81111C2 (en)	2007-12-10

Family

ID=27674912

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA20040907401A UA81111C2 (en)	2002-02-15	2003-01-17	Use of a microglia inhibitor for the production of a pharmaceutical agent that inhibits immune reactions mediated by interleukin 12 (il 12) and interferon-? (variants)

Country Status (21)

Country	Link
EP (1)	EP1474138A1 (sr)
JP (1)	JP2005522447A (sr)
KR (1)	KR20040084909A (sr)
CN (1)	CN1756546A (sr)
AR (1)	AR039556A1 (sr)
AU (1)	AU2003245523A1 (sr)
BR (1)	BR0307706A (sr)
CA (1)	CA2475770A1 (sr)
DE (1)	DE10207843A1 (sr)
EC (1)	ECSP045297A (sr)
MX (1)	MXPA04007943A (sr)
NO (1)	NO20043840L (sr)
PE (1)	PE20030906A1 (sr)
PL (1)	PL371327A1 (sr)
RS (1)	RS71304A (sr)
RU (1)	RU2004127677A (sr)
TW (1)	TW200306823A (sr)
UA (1)	UA81111C2 (sr)
UY (1)	UY27662A1 (sr)
WO (1)	WO2003068225A1 (sr)
ZA (1)	ZA200407382B (sr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10207844A1 (de) *	2002-02-15	2003-09-04	Schering Ag	1-Phenyl-2-heteroaryl-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
HRP20090646T1 (hr) *	2005-03-17	2010-01-31	Proyecto De Biomedicina Cima	Uporaba 5'-metiltioadenozina (mta) kod prevencije i/ili liječenja autoimunih bolesti i/ili odbacivanje transplantata
US9550737B2 (en) *	2012-06-11	2017-01-24	Ucb Biopharma Sprl	TNF -α modulating benzimidazoles
US9586949B2 (en)	2015-02-09	2017-03-07	Incyte Corporation	Aza-heteroaryl compounds as PI3K-gamma inhibitors
EP4086259A1 (en)	2015-11-06	2022-11-09	Incyte Corporation	Heterocyclic compounds as pi3k-gamma inhibitors
KR20180094989A (ko) *	2015-12-15	2018-08-24	더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 주니어 유니버시티	노화 관련 인지장애 및 신경염증의 예방 및/또는 치료 방법
WO2017120194A1 (en)	2016-01-05	2017-07-13	Incyte Corporation	Pyridine and pyridimine compounds as pi3k-gamma inhibitors
WO2017223414A1 (en)	2016-06-24	2017-12-28	Incyte Corporation	HETEROCYCLIC COMPOUNDS AS PI3K-γ INHIBITORS
IL295978B2 (en)	2017-10-18	2024-01-01	Incyte Corp	Condensed imidazole derivatives substituted by tertiary hydroxy groups as pi3k-gamma inhibitors
CR20250050A (es)	2018-09-05	2025-03-19	Incyte Corp	Formas cristalinas de un inhibidor de fosfoinositida 3–quinasa (pi3k) (divisional 2021-0165)
HUE066335T2 (hu)	2018-10-05	2024-07-28	Annapurna Bio Inc	Vegyületek és készítmények APJ receptor aktivitáshoz kapcsolódó állapotok kezelésére
CN112341450B (zh) *	2019-08-09	2022-05-17	成都先导药物开发股份有限公司	一种免疫调节剂
CN112341451B (zh) *	2019-08-09	2022-06-17	成都先导药物开发股份有限公司	一种免疫调节剂
CN115768757B (zh) *	2019-12-19	2025-07-11	美利坚合众国,由健康及人类服务部部长代表	Cd206调节剂及其用途和制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4330959A1 (de) *	1993-09-09	1995-03-16	Schering Ag	Neue Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
BR0107628A (pt) *	2000-01-14	2002-10-08	Schering Ag	l,2-diarilbenzimidazóis para tratamento de doenças que estão associadas a uma ativação microglial
DE10134775A1 (de) *	2001-07-06	2003-01-30	Schering Ag	1-Alkyl-2.aryl-benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
DE10135050A1 (de) *	2001-07-09	2003-02-06	Schering Ag	1-Ary1-2-N-, S- oder O-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate

2002
- 2002-02-15 DE DE10207843A patent/DE10207843A1/de not_active Ceased
2003
- 2003-01-17 CN CNA038039923A patent/CN1756546A/zh active Pending
- 2003-01-17 WO PCT/EP2003/000467 patent/WO2003068225A1/de not_active Ceased
- 2003-01-17 RS YU71304A patent/RS71304A/sr unknown
- 2003-01-17 RU RU2004127677/15A patent/RU2004127677A/ru unknown
- 2003-01-17 AU AU2003245523A patent/AU2003245523A1/en not_active Abandoned
- 2003-01-17 MX MXPA04007943A patent/MXPA04007943A/es unknown
- 2003-01-17 EP EP03739380A patent/EP1474138A1/de not_active Withdrawn
- 2003-01-17 BR BR0307706-3A patent/BR0307706A/pt not_active IP Right Cessation
- 2003-01-17 JP JP2003567407A patent/JP2005522447A/ja active Pending
- 2003-01-17 KR KR10-2004-7012557A patent/KR20040084909A/ko not_active Ceased
- 2003-01-17 UA UA20040907401A patent/UA81111C2/uk unknown
- 2003-01-17 CA CA002475770A patent/CA2475770A1/en not_active Abandoned
- 2003-01-17 PL PL03371327A patent/PL371327A1/xx not_active Application Discontinuation
- 2003-02-03 PE PE2003000119A patent/PE20030906A1/es not_active Application Discontinuation
- 2003-02-11 UY UY27662A patent/UY27662A1/es not_active Application Discontinuation
- 2003-02-12 AR ARP030100436A patent/AR039556A1/es unknown
- 2003-02-14 TW TW092103072A patent/TW200306823A/zh unknown
2004
- 2004-09-14 ZA ZA200407382A patent/ZA200407382B/en unknown
- 2004-09-14 EC EC2004005297A patent/ECSP045297A/es unknown
- 2004-09-14 NO NO20043840A patent/NO20043840L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20043840L (no)	2004-11-12
PE20030906A1 (es)	2004-01-17
UY27662A1 (es)	2003-09-30
EP1474138A1 (de)	2004-11-10
TW200306823A (en)	2003-12-01
AU2003245523A1 (en)	2003-09-04
CN1756546A (zh)	2006-04-05
MXPA04007943A (es)	2004-11-26
AR039556A1 (es)	2005-02-23
KR20040084909A (ko)	2004-10-06
ZA200407382B (en)	2005-09-14
JP2005522447A (ja)	2005-07-28
RS71304A (sr)	2006-10-27
WO2003068225A1 (de)	2003-08-21
PL371327A1 (en)	2005-06-13
DE10207843A1 (de)	2003-09-04
RU2004127677A (ru)	2005-06-10
BR0307706A (pt)	2005-01-11
CA2475770A1 (en)	2003-08-21
ECSP045297A (es)	2004-10-26

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