UA94404C2 - Новые композиции вакцин - Google Patents

Новые композиции вакцин

Info

Publication number
UA94404C2
UA94404C2 UAA200712656A UAA200712656A UA94404C2 UA 94404 C2 UA94404 C2 UA 94404C2 UA A200712656 A UAA200712656 A UA A200712656A UA A200712656 A UAA200712656 A UA A200712656A UA 94404 C2 UA94404 C2 UA 94404C2
Authority
UA
Ukraine
Prior art keywords
oil
vaccine formulations
novel vaccine
water
ionic
Prior art date
Application number
UAA200712656A
Other languages
English (en)
Ukrainian (uk)
Inventor
Алексис Ги Андре Паризо
Стефани Мари-Катрин Десгуйе-Блеше
Катрин Шарер
Клод Жан Мари Руле
Original Assignee
Мериал Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мериал Лимитед filed Critical Мериал Лимитед
Publication of UA94404C2 publication Critical patent/UA94404C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Данное изобретение относится к эмульсиям типа "масло-в-воде", их применению как адьювантов и фармацевтических, иммунологических композиций и композиций вакцин, которые могут содержать такие эмульсии. Эмульсия типа "масло-в-воде" (O/W) может включать водный раствор, который содержит иммуноген, минеральное масло, неионогенный липофильный этоксилированный спирт жирного строя и неионогенное гидрофильное поверхностно-активное вещество.
UAA200712656A 2005-04-15 2006-04-13 Новые композиции вакцин UA94404C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/107,000 US7691368B2 (en) 2005-04-15 2005-04-15 Vaccine formulations

Publications (1)

Publication Number Publication Date
UA94404C2 true UA94404C2 (ru) 2011-05-10

Family

ID=36950184

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200712656A UA94404C2 (ru) 2005-04-15 2006-04-13 Новые композиции вакцин

Country Status (24)

Country Link
US (1) US7691368B2 (ru)
EP (2) EP1888107B1 (ru)
JP (1) JP5093902B2 (ru)
KR (1) KR101292874B1 (ru)
CN (1) CN101184501A (ru)
AR (1) AR053360A1 (ru)
AU (2) AU2006236711B2 (ru)
BR (1) BRPI0610633B1 (ru)
CA (1) CA2604432C (ru)
CY (1) CY1113104T1 (ru)
DK (1) DK1888107T3 (ru)
ES (1) ES2389377T3 (ru)
IL (1) IL186600A (ru)
MX (1) MX2007012785A (ru)
MY (1) MY144189A (ru)
NZ (2) NZ584420A (ru)
PL (1) PL1888107T3 (ru)
PT (1) PT1888107E (ru)
RU (1) RU2422155C2 (ru)
SI (1) SI1888107T1 (ru)
TW (1) TWI376232B (ru)
UA (1) UA94404C2 (ru)
WO (1) WO2006113373A2 (ru)
ZA (1) ZA200708634B (ru)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US8703095B2 (en) 2005-07-07 2014-04-22 Sanofi Pasteur S.A. Immuno-adjuvant emulsion
CN101277717A (zh) * 2005-09-09 2008-10-01 英特威国际有限公司 Pcv-2疫苗
WO2007052055A1 (en) 2005-11-04 2007-05-10 Novartis Vaccines And Diagnostics Srl Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture
NZ594482A (en) 2005-11-04 2012-11-30 Novartis Vaccines & Diagnostic Influenza vaccines with reduced amount of oil-in-water emulsion as adjuvant
CA2628424A1 (en) 2005-11-04 2007-05-10 Novartis Vaccines And Diagnostics S.R.L. Adjuvanted influenza vaccines including cytokine-inducing agents
DK2275132T3 (da) 2005-12-29 2021-05-17 Boehringer Ingelheim Animal Health Usa Inc Multivalente pcv2-immunogeniske sammensætninger og fremgangsmåder til at fremstille dem
CA2635430A1 (en) * 2005-12-29 2007-08-23 Boehringer Ingelheim Vetmedica, Inc. Use of a pcv2 immunogenic composition for lessening clinical symptoms in pigs
FR2896162B1 (fr) 2006-01-13 2008-02-15 Sanofi Pasteur Sa Emulsion huile dans eau thermoreversible
JP2009528361A (ja) * 2006-03-03 2009-08-06 メリアル リミテッド マイコプラズマ・ハイオニューモニエワクチン
WO2007110776A1 (en) 2006-03-24 2007-10-04 Novartis Vaccines And Diagnostics Gmbh & Co Kg Storage of influenza vaccines without refrigeration
GB0614460D0 (en) 2006-07-20 2006-08-30 Novartis Ag Vaccines
NZ575271A (en) 2006-09-11 2011-09-30 Novartis Ag Making influenza virus vaccines without using eggs
WO2008064299A2 (en) * 2006-11-22 2008-05-29 Boehringer Ingelheim Vetmedica, Inc. Methods of reducing porcine circovirus-associated disease outbreaks
JP2011506264A (ja) 2006-12-06 2011-03-03 ノバルティス アーゲー インフルエンザウイルスの４つの株に由来する抗原を含むワクチン
WO2008073464A2 (en) * 2006-12-11 2008-06-19 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
PT2094872T (pt) * 2006-12-15 2017-04-27 Boehringer Ingelheim Vetmedica Inc Tratamento de porcos seropositivos para o anticorpo anti-pcv2 com antigénio de pcv2
EP1941903A1 (en) * 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
HUE031617T2 (en) 2007-04-06 2017-07-28 Takeda Vaccines Inc Methods and compositions for live attenuated viruses
PT2185191E (pt) 2007-06-27 2012-11-27 Novartis Ag Vacinas contra a gripe com baixo teor de aditivos
US20090017064A1 (en) * 2007-07-10 2009-01-15 Wyeth Methods and Compositions for Immunizing Pigs Against Porcine Circovirus
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
HRP20120433T1 (en) 2007-10-19 2012-07-31 Novartis@Ag Meningococcal vaccine formulations
GB0810305D0 (en) 2008-06-05 2008-07-09 Novartis Ag Influenza vaccination
DK2224951T3 (da) * 2007-12-21 2020-01-06 Zoetis Services Llc Varmebehandlede bakteriner og emulsionsvacciner, der er fremstillet af sådanne varmebehandlede bakteriner
CN101932336B (zh) * 2007-12-31 2014-07-09 贝林格尔.英格海姆维特梅迪卡有限公司 有外来氨基酸插入的pcv2 orf2病毒样颗粒
KR20100113582A (ko) 2008-01-23 2010-10-21 베링거잉겔하임베트메디카인코퍼레이티드 Ｐｃｖ2 마이코플라즈마 히오뉴모니에 면역원성 조성물 및 당해 조성물의 생산 방법
JP5518041B2 (ja) 2008-03-18 2014-06-11 ノバルティス アーゲー インフルエンザウイルスワクチン抗原の調製における改良
US9642908B2 (en) * 2008-07-30 2017-05-09 University Of Kentucky Research Foundation Equine disease model for herpesvirus neurologic disease and uses thereof
NZ591768A (en) 2008-09-18 2012-11-30 Novartis Ag Vaccine adjuvant combinations
MX2011005604A (es) 2008-11-28 2011-09-01 Merial Ltd Vacuna recombinante para influenza aviar y sus usos.
JP2012517416A (ja) 2009-02-10 2012-08-02 ノバルティス アーゲー 増加した量のｈ３抗原を含むインフルエンザワクチン
EA023662B1 (ru) 2009-02-10 2016-06-30 Новартис Аг Вакцины против гриппа со сниженным количеством сквалена
WO2010092476A1 (en) 2009-02-10 2010-08-19 Novartis Ag Influenza vaccine regimens for pandemic-associated strains
WO2010100632A2 (en) 2009-03-06 2010-09-10 Novartis Ag Chlamydia antigens
EP2228054A1 (en) * 2009-03-13 2010-09-15 ITALFARMACO S.p.A. Riluzole aqueous suspensions
EP3017826A1 (en) 2009-03-24 2016-05-11 Novartis AG Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
EP2419129A2 (en) 2009-04-14 2012-02-22 Novartis AG Compositions for immunising against staphylococcus aerus
PE20120909A1 (es) * 2009-05-19 2012-08-19 Bioproperties Pty Ltd Cepa de vacuna de mycoplasma hyopneumoniae sensible a la temperatura y usos de la misma
JP5836266B2 (ja) 2009-05-21 2015-12-24 ノバルティス アーゲー 非内因性ｐｏｌＩプロモーターを使用した逆遺伝学
EA201171491A1 (ru) 2009-05-29 2012-07-30 Новартис Аг Анализы гемагглютининов вируса гриппа
US10988511B2 (en) 2009-07-07 2021-04-27 Glaxosmithkline Biologicals Sa Conserved Escherichia bacterial IG-like domain (group 1) protein (ORF405) immunogens
CA2768343A1 (en) 2009-07-16 2011-01-20 Novartis Ag Detoxified escherichia coli immunogens
JP6166533B2 (ja) * 2009-07-31 2017-07-19 ナショナル リサーチ カウンシル オブ カナダ ピロリ菌リポ多糖類の外殻エピトープ
TWI627281B (zh) * 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低ｐｃｖ－２組合物殺病毒活性之方法及具有改良免疫原性之ｐｃｖ－２組合物
DK2475384T3 (en) * 2009-09-10 2016-10-24 Merial Inc NEW VACCINE FORMULATIONS COMPREHENSIVE saponin-CONTAINING ADJUVANTS
CN102695523A (zh) 2009-09-10 2012-09-26 诺华有限公司 针对呼吸道疾病的组合疫苗
GB0917003D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
GB0917002D0 (en) 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Improved shigella blebs
CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
KR20120083480A (ko) 2009-10-20 2012-07-25 노파르티스 아게 바이러스 구제를 위한 개선된 역유전학 방법
GB0918392D0 (en) 2009-10-20 2009-12-02 Novartis Ag Diagnostic and therapeutic methods
GB0919690D0 (en) 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
EP2519265B1 (en) 2009-12-30 2018-11-14 GlaxoSmithKline Biologicals SA Polysaccharide immunogens conjugated to e. coli carrier proteins
GB201003333D0 (en) 2010-02-26 2010-04-14 Novartis Ag Immunogenic proteins and compositions
WO2012020326A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
FR2957933B1 (fr) * 2010-03-24 2012-04-27 Seppic Sa Vaccin vivant pour maladies aviaires
GB201005625D0 (en) 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions
US9744228B2 (en) 2010-04-07 2017-08-29 Norvartis Ag Method for generating a parvovirus B19 virus-like particle
EP2563389B1 (en) 2010-04-30 2015-07-08 Temasek Life Sciences Laboratory Limited Universal vaccine against h5n1 lineages
ES2559445T3 (es) 2010-05-11 2016-02-12 Intervet International B.V. Vacuna contra Mycoplasma hyopneumoniae apta para la administración en presencia de anticuerpos de origen materno
JP5876036B2 (ja) 2010-05-21 2016-03-02 ノバルティス アーゲー インフルエンザウイルス再集合方法
GB201009861D0 (en) 2010-06-11 2010-07-21 Novartis Ag OMV vaccines
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
CA2804501C (en) 2010-07-06 2021-01-26 Novartis Ag Noro virus derived immunogenic compositions and methods
GB201017519D0 (en) 2010-10-15 2010-12-01 Novartis Vaccines Inst For Global Health S R L Vaccines
WO2012072769A1 (en) 2010-12-01 2012-06-07 Novartis Ag Pneumococcal rrgb epitopes and clade combinations
CN103533954B (zh) 2011-03-02 2015-09-09 诺华股份有限公司 含较低剂量的抗原和/或佐剂的联合疫苗
US10030052B2 (en) 2011-07-25 2018-07-24 Glaxosmithkline Biologicals Sa Parvovirus Vp1 unique region polypeptides and compositions thereof
EP2755683B1 (en) 2011-09-14 2019-04-03 GlaxoSmithKline Biologicals SA Methods for making saccharide-protein glycoconjugates
EP2768528A1 (en) 2011-10-20 2014-08-27 Novartis AG Adjuvanted influenza b virus vaccines for pediatric priming
EP2791680B1 (en) 2011-12-12 2015-12-09 Novartis AG Assay for influenza virus hemagglutinins
US20150044251A1 (en) 2011-12-23 2015-02-12 Novartis Ag Stable compositions for immunising against staphylococcus aureus
HUE033858T2 (en) 2012-02-14 2018-01-29 Merial Inc Rotavirus unit vaccines and method for their preparation and use
WO2013087945A2 (en) 2012-03-02 2013-06-20 Novartis Ag Influenza virus reassortment
WO2013182498A1 (en) 2012-06-04 2013-12-12 Novartis Ag Improved safety testing
TR201910573T4 (tr) 2012-08-31 2019-08-21 Glaxosmithkline Biologicals Sa Staphylococcus aureus'a karşı bağışıklık kazandırmak için stabilize edilmiş proteinler.
WO2014033191A1 (en) 2012-08-31 2014-03-06 Novartis Ag Stabilised proteins for immunising against staphylococcus aureus
HUE059179T2 (hu) 2012-09-10 2022-10-28 Galenbio Inc Vízimadárban Mycoplasma-fertõzés megelõzésére szolgáló oltóanyag
AU2013320313B2 (en) 2012-09-18 2018-07-12 Glaxosmithkline Biologicals Sa Outer membrane vesicles
MX2015004171A (es) 2012-10-02 2015-10-22 Glaxosmithkline Biolog Sa Conjugados de sacaridos no lineales.
GB201218195D0 (en) 2012-10-10 2012-11-21 Istituto Zooprofilattico Sperimentale Delle Venezie Composition
CN105142666A (zh) 2012-11-30 2015-12-09 葛兰素史密丝克莱恩生物有限公司 假单胞菌抗原和抗原组合
US9708585B2 (en) 2012-12-03 2017-07-18 Seqirus UK Limited Influenza virus reassortment
CA2905612A1 (en) 2013-03-13 2014-09-18 Novartis Ag Influenza virus reassortment
EP2994162B1 (en) 2013-05-08 2021-04-07 Pharmgate Biologics Inc. Vaccine for pcv2 and mycoplasma
JP2016521282A (ja) 2013-05-10 2016-07-21 ノバルティス アーゲー インフルエンザワクチンにおけるナルコレプシーのリスクの回避
DE202013005100U1 (de) 2013-06-05 2013-08-26 Novartis Ag Influenza Virus Reassortierung
DE202013005130U1 (de) 2013-06-05 2013-09-10 Novartis Ag Influenza Virus Reassortierung
CN105722976A (zh) 2013-06-06 2016-06-29 诺华股份有限公司 流感病毒重配
ES2778425T3 (es) 2013-10-02 2020-08-10 Boehringer Ingelheim Animal Health Usa Inc Variante de la proteína ORF2 del PCV2 y partículas similares a virus compuestas por esta
PL3076996T3 (pl) * 2013-12-03 2020-05-18 Intervet International B.V. Szczepionka przeciwko cirkowirusowi świń typu 2
CN103751779A (zh) * 2014-02-25 2014-04-30 中国农业科学院上海兽医研究所 O型口蹄疫多肽的泊洛沙姆凝胶佐剂
MX377794B (es) 2014-03-26 2025-03-10 Glaxosmithkline Biologicals Sa Antigenos estafilococicos mutantes.
US9713639B2 (en) 2014-05-19 2017-07-25 Merial, Inc. Recombinant spike protein subunit based vaccine for porcine epidemic diarrhea virus (PEDV)
US20150359880A1 (en) * 2014-06-16 2015-12-17 Biomune Company Dual adjuvant vaccine compositions, preparation and uses
CN105288614A (zh) * 2014-06-18 2016-02-03 潘皓 一种疫苗组合物及其制备方法
US10010605B2 (en) 2014-09-23 2018-07-03 Merial, Inc. FMDV recombinant vaccines and uses thereof
JP2015120709A (ja) * 2015-01-09 2015-07-02 ラボラトリオ アヴィメキシコ エスエー ディーイー シーヴィーＬａｂｏｒａｔｏｒｉｏ Ａｖｉ−Ｍｅｘ，Ｓ．Ａ． Ｄｅ Ｃ．Ｖ． 遺伝子組み換え不活性化ウィルスベクターワクチン
NZ739260A (en) 2015-06-26 2019-09-27 Boehringer Ingelheim Animal Health Usa Inc Inactivated canine influenza vaccines and methods of making and uses thereof
KR20180035807A (ko) 2015-06-26 2018-04-06 세퀴러스 유케이 리미티드 항원적으로 매치된 인플루엔자 백신
AU2016290603B2 (en) 2015-07-07 2022-06-02 Seqirus UK Limited Influenza potency assays
JP6986019B2 (ja) 2015-10-08 2021-12-22 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド レプトスピラ用生弱毒化異種ワクチン
JP6797206B2 (ja) 2015-11-23 2020-12-09 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド Ｆｍｄｖ及びｅ２融合タンパク質並びにその使用
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途
JOP20190088A1 (ar) 2016-10-21 2019-04-21 Us Agriculture نواقل مؤتلفة للتعبير عن مولدات مضاد فيروس انفلونزا الطيور و استخداماتها
BR112019010394A2 (pt) * 2016-11-29 2019-09-03 Intervet International B.V. vacina suína
RU2752836C2 (ru) 2016-12-14 2021-08-09 БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. Рекомбинантные hvt-векторы, экспрессирующие множественные антигены патогенов птиц, и содержащие их вакцины
US12246090B2 (en) 2018-10-16 2025-03-11 Intervet Inc. Stable emulsions of bacterial antigens
FR3092754B1 (fr) * 2019-02-18 2022-06-03 Total Marketing Services Composition adjuvante pour vaccin
EP4061930A1 (en) 2019-11-18 2022-09-28 Seqirus Pty Ltd Method for producing reassortant influenza viruses
CN113546162B (zh) * 2021-05-31 2023-07-18 江苏省农业科学院 一种支原体疫苗及其制备方法
WO2024133656A1 (en) 2022-12-22 2024-06-27 Ceva Sante Animale Oil adjuvant compositions and vaccine emulsions comprising such oil adjuvant compositions

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250289A (en) * 1987-07-24 1993-10-05 The Boots Company Plc Sunscreen compositions
US5376369A (en) * 1987-11-03 1994-12-27 Syntex (U.S.A.) Inc. Vaccine adjuvant
PL155558B1 (pl) * 1988-01-28 1991-12-31 Inst Ciezkiej Syntezy Orga Sposób wytwarzania kompozycji emulgującej
AU657907B2 (en) 1990-05-29 1995-03-30 Wyeth Holdings Corporation Mycoplasma hyopneumoniae vaccine
US6197311B1 (en) * 1991-07-25 2001-03-06 Idec Pharmaceuticals Corporation Induction of cytotoxic T-lymphocyte responses
US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US5338543A (en) 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
US5695766A (en) 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
PL178609B1 (pl) 1993-02-08 2000-05-31 Bayer Ag Izolat wirusa zespołu reprodukcyjnego i oddechowego świń zwanego PRRSV, sposób namnażania izolatu PRRSV, klon linii komórkowej, hodowla tkankowa zawierająca izolat PRRSV, szczepionka efektywna w ochronie świń przeciw PRRSV oraz sposób wytwarzania szczepionki efektywnej w ochronie świń przeciw PRRSV
FR2723740B1 (fr) 1994-08-16 1996-11-08 Pasteur Merieux Serums Vacc Procede de preparation d'antigenes du virus grippal, antigenes obtenus et leurs applications
US5985177A (en) 1995-12-14 1999-11-16 Shiseido Co., Ltd. O/W/O type multiple emulsion and method of preparing the same
US5866401A (en) 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US5980912A (en) 1997-03-25 1999-11-09 Zonagen, Inc. Chitosan induced immunopotentiation
US6391314B1 (en) 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
US20030165545A1 (en) * 2002-01-30 2003-09-04 Allergan, Inc. Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same
RU2233175C2 (ru) * 2002-06-25 2004-07-27 Всероссийский научно-исследовательский институт птицеводства Вакцинный препарат для профилактики аденовирусного гепатита с включениями - гидроперикардита кур
PL1651265T3 (pl) 2003-07-24 2008-10-31 Merial Ltd Formulacje szczepionek zawierających emulsję olej w wodzie
US9390965B2 (en) 2013-12-20 2016-07-12 Taiwan Semiconductor Manufacturing Co., Ltd. Air-gap forming techniques for interconnect structures

Also Published As

Publication number Publication date
JP5093902B2 (ja) 2012-12-12
EP1888107A2 (en) 2008-02-20
HK1116085A1 (en) 2008-12-19
KR20070122550A (ko) 2007-12-31
AU2006236711B2 (en) 2010-07-29
WO2006113373A2 (en) 2006-10-26
SI1888107T1 (sl) 2012-09-28
AR053360A1 (es) 2007-05-02
IL186600A (en) 2014-05-28
CN101184501A (zh) 2008-05-21
TWI376232B (en) 2012-11-11
AU2006236711A1 (en) 2006-10-26
NZ562663A (en) 2010-04-30
ES2389377T3 (es) 2012-10-25
US7691368B2 (en) 2010-04-06
CA2604432A1 (en) 2006-10-26
CA2604432C (en) 2013-06-11
EP2422809A1 (en) 2012-02-29
CY1113104T1 (el) 2016-04-13
TW200716165A (en) 2007-05-01
PT1888107E (pt) 2012-07-26
BRPI0610633A2 (pt) 2010-07-13
EP1888107B1 (en) 2012-06-13
ZA200708634B (en) 2008-10-29
WO2006113373A3 (en) 2007-02-01
KR101292874B1 (ko) 2013-08-05
AU2010206041A1 (en) 2010-08-19
MX2007012785A (es) 2008-01-11
RU2007142202A (ru) 2009-05-20
BRPI0610633B1 (pt) 2021-07-20
US20060233831A1 (en) 2006-10-19
AU2010206041B2 (en) 2012-08-02
MY144189A (en) 2011-08-15
IL186600A0 (en) 2008-01-20
DK1888107T3 (da) 2012-07-23
NZ584420A (en) 2011-11-25
RU2422155C2 (ru) 2011-06-27
JP2008536860A (ja) 2008-09-11
PL1888107T3 (pl) 2012-11-30

Similar Documents

Publication Publication Date Title
TW200716165A (en) Novel vaccine formulations
AR121096A2 (es) Formulaciones de vacunas que comprenden adyuvantes con saponina
ES2585810T3 (es) Uso de un virus de la gripe y un adyuvante de emulsión de aceite en agua para inducir respuesta de células T CD4 y/o una respuesta de células B de memoria mejorada
HRP20080235T3 (hr) Formulacija vakcine koja sadrži emulziju ulje-u-vodi
BRPI0717219B8 (pt) composição imunogênica, e, uso de uma composição imunogênica
CY1108994T1 (el) Θερμοαναστρεψιμο ανοσοενισχυτικο γαλακτωμα
PE20031049A1 (es) Composicion cosmetica multifasica
BRPI0815828A2 (pt) Formulação de emulsão que impede interação através da interface água-óleo
EP2269644A3 (en) Microfluidized oil-in-water emulsions and vaccine compositions
BR0000126A (pt) Adjuvantes para uso em vacinas
EA200901161A1 (ru) Вакцина против гриппа в виде эмульсии типа "масло в воде"
EA200501002A1 (ru) Эмульсия, содержащая растительный экстракт, и ее применение
EA201001479A1 (ru) Вакцина
AR075437A1 (es) Composicion inmunogenica que comprende al menos un antigeno del virus del dengue inactivado y un adyuvante sin aluminio, metodo para producir dicha vacuna y su uso para preparar un medicamento
PL1613720T3 (pl) Czyszczące kompozycje emulsji wielokrotnych
SE0000774D0 (sv) New formulation
MX384242B (es) Composicion de peroxido organico sin agente coloide.
EA201001478A1 (ru) Вакцина
BR112012021108A2 (pt) composições biocidas, e, uso de valerolactona e/ou de seus derivados de amida
CO2023013231A2 (es) Composiciones de espirotetramato que comprenden adyuvantes
SE0000730D0 (sv) Lipid carrier
MX2007000120A (es) Composicion herbacea.
BR0314443A (pt) Emulsão de água em óleo, método para a preparação de uma emulsão de água em óleo e uso de ácido fólico
MX2020001623A (es) Sistema emulsionante, producto de cuidado personal, metodo y uso.
UY29523A1 (es) Formulaciones de vacunas novedosas