UY38207A - Anticuerpos anti-esclerostina - Google Patents

Anticuerpos anti-esclerostina

Info

Publication number
UY38207A
UY38207A UY0001038207A UY38207A UY38207A UY 38207 A UY38207 A UY 38207A UY 0001038207 A UY0001038207 A UY 0001038207A UY 38207 A UY38207 A UY 38207A UY 38207 A UY38207 A UY 38207A
Authority
UY
Uruguay
Prior art keywords
sclerostin
sclerostin antibodies
binding
compositions
antibodies capable
Prior art date
Application number
UY0001038207A
Other languages
English (en)
Spanish (es)
Inventor
Christopher Paszty
Kim Robinson Martyn
Kevin Graham
James Henry Alistair
Sue Hoffmann Kelly
John Latham
Alastair Lawson
Sen Lu Hsieng
Andy P0PPLEWELL
Wenyan Shen
David Winkler
George Winiers Aaron
Original Assignee
Amgen Inc
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36992590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY38207(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc, Ucb Sa filed Critical Amgen Inc
Publication of UY38207A publication Critical patent/UY38207A/es

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
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  • Mycology (AREA)
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UY0001038207A 2005-05-03 2006-05-02 Anticuerpos anti-esclerostina UY38207A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US67758305P 2005-05-03 2005-05-03
US77684706P 2006-02-24 2006-02-24
US78224406P 2006-03-13 2006-03-13
US79264506P 2006-04-17 2006-04-17
US11/411,003 US7592429B2 (en) 2005-05-03 2006-04-25 Sclerostin-binding antibody
UY29514A UY29514A1 (es) 2005-05-03 2006-05-02 Agentes de unión

Publications (1)

Publication Number Publication Date
UY38207A true UY38207A (es) 2020-11-30

Family

ID=36992590

Family Applications (2)

Application Number Title Priority Date Filing Date
UY0001038207A UY38207A (es) 2005-05-03 2006-05-02 Anticuerpos anti-esclerostina
UY29514A UY29514A1 (es) 2005-05-03 2006-05-02 Agentes de unión

Family Applications After (1)

Application Number Title Priority Date Filing Date
UY29514A UY29514A1 (es) 2005-05-03 2006-05-02 Agentes de unión

Country Status (43)

Country Link
US (8) US7592429B2 (2)
EP (7) EP1891101B8 (2)
JP (4) JP5462484B2 (2)
KR (4) KR101450888B1 (2)
CN (4) CN103819558B (2)
AR (1) AR053266A1 (2)
AU (2) AU2006242476B2 (2)
BE (1) BE2020C508I2 (2)
BR (2) BR122020023315B1 (2)
CA (2) CA2607197C (2)
CR (1) CR9524A (2)
CY (4) CY1114350T1 (2)
DK (3) DK1891101T3 (2)
EA (2) EA037044B1 (2)
ES (4) ES2902548T3 (2)
FR (1) FR20C1010I2 (2)
GE (2) GEP20125594B (2)
GT (1) GT200600186A (2)
HR (3) HRP20130803T1 (2)
HU (3) HUE057097T2 (2)
IL (3) IL187106A (2)
LT (2) LT3670528T (2)
LU (1) LUC00151I2 (2)
MA (1) MA29528B1 (2)
ME (2) ME02247B (2)
MX (3) MX358705B (2)
MY (1) MY163480A (2)
NL (1) NL301034I2 (2)
NO (4) NO346914B1 (2)
NZ (2) NZ563539A (2)
PE (1) PE20070317A1 (2)
PH (1) PH12015501848A1 (2)
PL (3) PL3670528T3 (2)
PT (3) PT1891101E (2)
RS (3) RS54049B1 (2)
SG (1) SG10201403400UA (2)
SI (3) SI3670528T1 (2)
TN (1) TNSN07406A1 (2)
TW (5) TWI778444B (2)
UA (1) UA123695C2 (2)
UY (2) UY38207A (2)
WO (1) WO2006119107A2 (2)
ZA (1) ZA200709480B (2)

Families Citing this family (225)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
ATE481487T1 (de) * 1998-11-27 2010-10-15 Ucb Sa Zusammensetzungen und verfahren zur erhöhung der knochenmineralisierung
US7799523B2 (en) 2002-04-03 2010-09-21 Celltech R & D, Inc. Association of polymorphisms in the SOST gene region with bone mineral density
US7893218B2 (en) * 2003-06-16 2011-02-22 Stowers Institute For Medical Research Antibodies that specifically bind SOST peptides
US7585501B2 (en) 2002-06-14 2009-09-08 Stowers Institute For Medical Research Compositions and methods for treating kidney disease
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HUE057097T2 (hu) 2022-04-28
JP5391360B2 (ja) 2014-01-15
US11939372B2 (en) 2024-03-26
SG10201403400UA (en) 2014-10-30
PL2325199T3 (pl) 2015-08-31
TWI712613B (zh) 2020-12-11
JP2014061000A (ja) 2014-04-10
EA201400933A1 (ru) 2015-04-30
CA2947080A1 (en) 2006-11-09
EP2264063B1 (en) 2018-06-27
EP2264063A1 (en) 2010-12-22
EP2336163A1 (en) 2011-06-22
PT1891101E (pt) 2013-08-23
SI3670528T1 (sl) 2022-01-31
NZ591636A (en) 2012-10-26
HUE025530T2 (en) 2016-04-28
KR20140037293A (ko) 2014-03-26
NO20076046L (no) 2008-01-30
BR122020023315B1 (pt) 2021-06-08
EP1891101A2 (en) 2008-02-27
US20130121997A1 (en) 2013-05-16
SI2325199T1 (sl) 2015-07-31
TW201323438A (zh) 2013-06-16
LTPA2020506I1 (lt) 2020-04-27
NO345294B1 (no) 2020-11-30
US7872106B2 (en) 2011-01-18
ES2902548T3 (es) 2022-03-28
JP2014012001A (ja) 2014-01-23
FR20C1010I2 (fr) 2021-03-05
CY2020009I1 (el) 2020-11-25
UA123695C2 (uk) 2021-05-19
IL187106A (en) 2015-10-29
TW202323271A (zh) 2023-06-16
NO346914B1 (no) 2023-02-27
GEP20125594B (en) 2012-08-10
CR9524A (es) 2008-05-21
JP5462484B2 (ja) 2014-04-02
TW201741332A (zh) 2017-12-01
RS54049B1 (sr) 2015-10-30
NL301034I2 (nl) 2020-05-13
SI1891101T1 (sl) 2013-10-30
US20090304713A1 (en) 2009-12-10
CY1124802T1 (el) 2022-11-25
CY1116525T1 (el) 2017-03-15
IL224967B (en) 2019-03-31
US20130203965A1 (en) 2013-08-08
PL1891101T3 (pl) 2013-11-29
US20200048338A1 (en) 2020-02-13
CN103435698A (zh) 2013-12-11
PL3670528T3 (pl) 2022-01-31
BRPI0610197B1 (pt) 2021-05-11
KR20150117302A (ko) 2015-10-19
UY29514A1 (es) 2006-11-30
NO348331B1 (no) 2024-11-25
US8383801B2 (en) 2013-02-26
HRP20211904T1 (hr) 2022-03-04
EA037044B1 (ru) 2021-01-29
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US20070110747A1 (en) 2007-05-17
EP3670528B1 (en) 2021-09-08

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