YU44788B - Process for making ready for use solution for injections containing antitumor antracyclic glicoside - Google Patents

Process for making ready for use solution for injections containing antitumor antracyclic glicoside

Info

Publication number: YU44788B
Authority: YU; Yugoslavia
Prior art keywords: glicoside; antracyclic; use solution; injections containing; making ready
Prior art date: 1985-08-02

Application number

YU1035/86A

Other languages

English (en)

Other versions

YU103586A (en

Inventor

Gaetano Gatti

Diego Oldani

Giuseppe Bottoni

Carlo Confalonieri

Luciano Gambini

Ponti Roberto De

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-02

Filing date

1986-06-16

Publication date

1991-02-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10583216&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU44788(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-06-16 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1986-06-16 Priority to SI8611035A priority Critical patent/SI8611035A8/sl

1988-04-30 Publication of YU103586A publication Critical patent/YU103586A/xx

1991-02-28 Publication of YU44788B publication Critical patent/YU44788B/xx

1992-09-28 Priority to HRP-1035/86A priority patent/HRP920525B1/xx

1997-08-14 Priority to BA970187A priority patent/BA97187B1/bs

Links

230000000259 anti-tumor effect Effects 0.000 title 1
239000007924 injection Substances 0.000 title 1
238000002347 injection Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000000243 solution Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Inorganic Chemistry (AREA)
Dermatology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)

YU1035/86A 1985-08-02 1986-06-16 Process for making ready for use solution for injections containing antitumor antracyclic glicoside YU44788B (en)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
SI8611035A SI8611035A8 (sl)	1985-08-02	1986-06-16	Postopek pripravljanja injekcijske raztopine, pripravljene za uporabo, ki vsebuje protitumorni, antraciklinski glikozid
HRP-1035/86A HRP920525B1 (en)	1985-08-02	1992-09-28	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
BA970187A BA97187B1 (bs)	1985-08-02	1997-08-14	Postupak za pravljenje rastvora za injekcije spremnog za koriscenje koji sadrzi antitumorni antraciklinski glikozid

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB858519452A GB8519452D0 (en)	1985-08-02	1985-08-02	Injectable solutions

Publications (2)

Publication Number	Publication Date
YU103586A YU103586A (en)	1988-04-30
YU44788B true YU44788B (en)	1991-02-28

Family

ID=10583216

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
YU1035/86A YU44788B (en)	1985-08-02	1986-06-16	Process for making ready for use solution for injections containing antitumor antracyclic glicoside

Country Status (34)

Country	Link
US (1)	US4946831A (cs)
JP (1)	JPH0655667B2 (cs)
KR (1)	KR920001773B1 (cs)
CN (1)	CN1064531C (cs)
AT (1)	AT397463B (cs)
BE (1)	BE905202A (cs)
BG (1)	BG60425B2 (cs)
CA (1)	CA1291037C (cs)
CH (2)	CH668911C1 (cs)
CS (1)	CS277561B6 (cs)
CY (1)	CY1592A (cs)
DE (1)	DE3621844C2 (cs)
DK (1)	DK167557B1 (cs)
ES (1)	ES8801580A1 (cs)
FI (1)	FI86800C (cs)
FR (1)	FR2585569B1 (cs)
GB (2)	GB8519452D0 (cs)
GR (1)	GR861556B (cs)
HK (1)	HK93990A (cs)
HU (1)	HU196123B (cs)
IE (1)	IE59297B1 (cs)
IL (1)	IL79129A (cs)
IT (1)	IT1204906B (cs)
NL (2)	NL191507C (cs)
NO (1)	NO170913C (cs)
NZ (1)	NZ216604A (cs)
PH (1)	PH22332A (cs)
PT (1)	PT82865B (cs)
RU (2)	RU1837883C (cs)
SE (1)	SE466383C (cs)
SG (1)	SG80690G (cs)
UA (1)	UA29383C2 (cs)
YU (1)	YU44788B (cs)
ZA (1)	ZA864792B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5124317A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.P.A.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.R.L.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en)	1985-08-02	1999-11-02	Pharmacia & Upjohn Company	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
IT1226072B (it) *	1986-12-05	1990-12-10	Erba Farmitalia	Soluzioni iniettabili pronte all'uso contenenti un glicoside antraciclinico antitumorale.
FI883337L (fi) *	1987-07-16	1989-01-17	Bristol Myers Co	Icke-vattenloesningar av doxorubicinhydroklorin.
FI883338A7 (fi) *	1987-07-16	1989-01-17	Bristol Myers Squibb Co	Doksorubisiinihydrokloridin vesiliuoksia
DE3801178A1 (de) *	1988-01-18	1989-07-27	Hoechst Ag	Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
EP0372889B1 (en) *	1988-12-05	1993-03-24	Bristol-Myers Squibb Company	Doxorubicin solutions
FI895733A7 (fi) *	1988-12-05	1990-06-06	Bristol Myers Squibb Co	Doksorubisiinin vesiliuoksia
GB9200247D0 (en) *	1992-01-07	1992-02-26	Erba Carlo Spa	Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation
DE19544532C2 (de) *	1995-11-29	1997-12-11	Pharma Dynamics Gmbh	Verfahren zum Herstellen eines Doxorubicin-Lyophilisats
EP0848009B1 (en) *	1996-12-16	2000-08-16	Pharmachemie B.V.	A process for preparing epirubicin or acid addition salts thereof from daunorubicin
BR9713661A (pt)	1996-12-30	2000-10-24	Battelle Memorial Institute	Formulação e método para o tratamento de neoplasmas por inalação
US20090253220A1 (en) *	2003-10-28	2009-10-08	Sukanta Banerjee	Absorbing Biomolecules into Gel-Shell Beads
WO2006122309A2 (en) *	2005-05-11	2006-11-16	Sicor, Inc.	Stable lyophilized anthracycline glycosides
EP2771034B1 (en) *	2011-10-25	2018-08-08	Nektar Therapeutics	Topoisomerase-i and-ii inhibitors for use in the treatment of patients suffering from cancer
CN102614118B (zh) *	2012-03-15	2014-04-30	北京协和药厂	注射用盐酸表柔比星制剂的制备方法及制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU33730B (en) *	1967-04-18	1978-02-28	Farmaceutici Italia	Process for preparing a novel antibiotic substance and salts thereof
GB1457632A (en) *	1974-03-22	1976-12-08	Farmaceutici Italia	Adriamycins
GB1500421A (en) *	1975-01-22	1978-02-08	Farmaceutici Italia	Optically active anthracyclinones
US4039663A (en) *	1975-03-19	1977-08-02	Societa' Farmaceutici Italia S.P.A.	Daunomycins, process for their uses and intermediates
FR2314726A1 (fr) *	1975-06-16	1977-01-14	Rhone Poulenc Ind	Nouveaux derives du naphtagene, leur preparation et les compositions qui les contiennent
GB1511559A (en) *	1975-09-26	1978-05-24	Farmaceutici Italia	Anthracycline glycosides
FR2397425A1 (fr) *	1977-07-11	1979-02-09	Rhone Poulenc Ind	Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
DE2738656A1 (de) *	1977-08-26	1979-03-08	Microbial Chem Res Found	Anthracyclinglycoside, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4177264A (en) *	1977-10-17	1979-12-04	Sri International	N-benzyl anthracyclines
GB2007645B (en) *	1977-10-17	1982-05-12	Stanford Res Inst Int	Benzyl anthracyclines and pharmaceutical compositions containing them
FR2430425A1 (fr) *	1978-07-07	1980-02-01	Rhone Poulenc Ind	Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2433027A1 (fr) *	1978-08-08	1980-03-07	Rhone Poulenc Ind	Nouveau procede de preparation de derives de la doxorubicine
US4325947A (en) *	1981-05-12	1982-04-20	Farmitalia Carlo Erba S.P.A.	4-Demethoxy-4'-deoxydoxorubicin
US4438105A (en) *	1982-04-19	1984-03-20	Farmaitalia Carlo Erba S.P.A	4'-Iododerivatives of anthracycline glycosides
US4464529A (en) *	1982-07-20	1984-08-07	Sri International	Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
JPS6092212A (ja) *	1983-10-26	1985-05-23	Kyowa Hakko Kogyo Co Ltd	ドキソルビシン塩の製剤
IT1226072B (it) *	1986-12-05	1990-12-10	Erba Farmitalia	Soluzioni iniettabili pronte all'uso contenenti un glicoside antraciclinico antitumorale.

1985
- 1985-08-02 GB GB858519452A patent/GB8519452D0/en active Pending
1986
- 1986-06-16 YU YU1035/86A patent/YU44788B/xx unknown
- 1986-06-16 GR GR861556A patent/GR861556B/el unknown
- 1986-06-17 IL IL79129A patent/IL79129A/xx not_active IP Right Cessation
- 1986-06-17 IE IE159886A patent/IE59297B1/en not_active IP Right Cessation
- 1986-06-18 GB GB8614800A patent/GB2178311B/en not_active Expired
- 1986-06-19 ES ES556291A patent/ES8801580A1/es not_active Expired
- 1986-06-19 FI FI862629A patent/FI86800C/fi not_active IP Right Cessation
- 1986-06-19 SE SE8602743A patent/SE466383C/sv not_active IP Right Cessation
- 1986-06-20 FR FR868608964A patent/FR2585569B1/fr not_active Expired - Lifetime
- 1986-06-20 NZ NZ216604A patent/NZ216604A/xx unknown
- 1986-06-20 HU HU862614A patent/HU196123B/hu unknown
- 1986-06-24 CH CH2534/86A patent/CH668911C1/de not_active IP Right Cessation
- 1986-06-24 CH CH02158/99A patent/CH690490C2/de not_active IP Right Cessation
- 1986-06-25 CS CS864708A patent/CS277561B6/cs not_active IP Right Cessation
- 1986-06-26 IT IT20917/86A patent/IT1204906B/it active Protection Beyond IP Right Term
- 1986-06-26 NO NO19862587A patent/NO170913C/no not_active IP Right Cessation
- 1986-06-27 JP JP61149878A patent/JPH0655667B2/ja not_active Expired - Lifetime
- 1986-06-27 ZA ZA864792A patent/ZA864792B/xx unknown
- 1986-06-27 CA CA000512613A patent/CA1291037C/en not_active Expired - Lifetime
- 1986-06-27 RU SU864027713A patent/RU1837883C/ru active
- 1986-06-27 PT PT82865A patent/PT82865B/pt unknown
- 1986-06-27 NL NL8601698A patent/NL191507C/nl not_active IP Right Cessation
- 1986-06-27 UA UA5011936A patent/UA29383C2/uk unknown
- 1986-06-27 DK DK306286A patent/DK167557B1/da not_active IP Right Cessation
- 1986-06-28 CN CN86104283A patent/CN1064531C/zh not_active Expired - Lifetime
- 1986-06-28 KR KR1019860005231A patent/KR920001773B1/ko not_active Expired
- 1986-06-30 DE DE3621844A patent/DE3621844C2/de not_active Revoked
- 1986-06-30 PH PH33966A patent/PH22332A/en unknown
- 1986-06-30 AT AT0176886A patent/AT397463B/de active Protection Beyond IP Right Term
- 1986-07-31 BE BE0/216997A patent/BE905202A/fr not_active IP Right Cessation
1989
- 1989-07-27 US US07/385,999 patent/US4946831A/en not_active Expired - Lifetime
1990
- 1990-10-04 SG SG806/90A patent/SG80690G/en unknown
- 1990-11-15 HK HK939/90A patent/HK93990A/xx not_active IP Right Cessation
1992
- 1992-04-03 CY CY1592A patent/CY1592A/en unknown
- 1992-06-24 RU SU5011936A patent/RU2110263C1/ru active
1993
- 1993-12-21 BG BG098321A patent/BG60425B2/bg unknown
2000
- 2000-07-18 NL NL300011C patent/NL300011I1/nl unknown

Also Published As

Publication number	Publication date
HU196123B (en)	1988-10-28
NO862587D0 (no)	1986-06-26
IL79129A (en)	1992-03-29
NO170913C (no)	2003-10-10
JPH0655667B2 (ja)	1994-07-27
DK167557B1 (da)	1993-11-22
SE8602743L (sv)	1987-02-03
PT82865A (en)	1986-07-01
IT1204906B (it)	1989-03-10
DK306286A (da)	1987-02-03
US4946831A (en)	1990-08-07
PT82865B (pt)	1989-01-17
RU2110263C1 (ru)	1998-05-10
FI862629L (fi)	1987-02-03
ATA176886A (de)	1993-09-15
FI86800C (fi)	1999-10-28
RU1837883C (ru)	1993-08-30
CN86104283A (zh)	1987-01-28
AU5885886A (en)	1987-02-12
BG60425B2 (bg)	1995-03-31
CH690490C2 (de)	2000-09-29
GR861556B (en)	1986-10-17
KR920001773B1 (ko)	1992-03-02
NL191507C (nl)	2000-02-16
NL300011I1 (nl)	2000-10-02
NO170913B (no)	1992-09-21
DE3621844A1 (de)	1987-03-05
BE905202A (fr)	1987-02-02
CN1064531C (zh)	2001-04-18
NO862587L (no)	1987-02-03
NL8601698A (nl)	1987-03-02
FI862629A0 (fi)	1986-06-19
HK93990A (en)	1990-11-23
GB8519452D0 (en)	1985-09-11
IE861598L (en)	1987-02-02
SG80690G (en)	1990-11-23
PH22332A (en)	1988-07-29
IE59297B1 (en)	1994-02-09
NZ216604A (en)	1989-10-27
ES8801580A1 (es)	1988-02-16
ES556291A0 (es)	1988-02-16
JPS6248629A (ja)	1987-03-03
GB2178311B (en)	1989-10-11
CH668911C1 (de)	2000-05-31
CH668911A5 (de)	1989-02-15
DK306286D0 (da)	1986-06-27
DE3621844C2 (de)	1994-02-17
HUT42326A (en)	1987-07-28
IT8620917A0 (it)	1986-06-26
FI86800B (fi)	1992-07-15
SE466383B (sv)	1992-02-10
NL191507B (nl)	1995-04-18
CA1291037C (en)	1991-10-22
SE8602743D0 (sv)	1986-06-19
CS277561B6 (en)	1993-03-17
ZA864792B (en)	1988-02-24
FR2585569B1 (fr)	1990-01-19
SE466383C (sv)	1996-02-19
CS470886A3 (en)	1992-11-18
AU598197B2 (en)	1990-06-21
GB8614800D0 (en)	1986-07-23
YU103586A (en)	1988-04-30
GB2178311A (en)	1987-02-11
CY1592A (en)	1992-04-03
IL79129A0 (en)	1986-09-30
FR2585569A1 (fr)	1987-02-06
KR870001828A (ko)	1987-03-28
AT397463B (de)	1994-04-25
UA29383C2 (uk)	2000-11-15

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