ZA200209807B - Non-nucleoside reverse transcriptase inhibitors. - Google Patents

Non-nucleoside reverse transcriptase inhibitors. Download PDF

Info

Publication number: ZA200209807B
Authority: ZA; South Africa
Prior art keywords: mmol; solution; compound; pharmaceutically acceptable; ethyl
Prior art date: 2000-06-16

Application number

ZA200209807A

Other languages

English (en)

Inventor

Bruno Simoneau

Original Assignee

Boehringer Ingelheim Ca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-16

Filing date

2002-12-03

Publication date

2003-10-16

2002-12-03 Application filed by Boehringer Ingelheim Ca Ltd filed Critical Boehringer Ingelheim Ca Ltd

2003-10-16 Publication of ZA200209807B publication Critical patent/ZA200209807B/en

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)

ZA200209807A 2000-06-16 2002-12-03 Non-nucleoside reverse transcriptase inhibitors. ZA200209807B (en)

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US21232900P	2000-06-16	2000-06-16
US25663800P	2000-12-18	2000-12-18
PCT/CA2001/000890 WO2001096338A1 (en)	2000-06-16	2001-06-14	Non-nucleoside reverse transcriptase inhibitors

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US (1)	US6420359B1 (de)
EP (1)	EP1294720B1 (de)
JP (1)	JP3923894B2 (de)
KR (1)	KR20030017540A (de)
CN (1)	CN1178939C (de)
AR (1)	AR028958A1 (de)
AT (1)	ATE322492T1 (de)
AU (2)	AU7037001A (de)
BG (1)	BG107348A (de)
BR (1)	BR0102377A (de)
CA (1)	CA2411766C (de)
CZ (1)	CZ20024114A3 (de)
DE (1)	DE60118560T2 (de)
DK (1)	DK1294720T3 (de)
EA (1)	EA005598B1 (de)
EE (1)	EE200200690A (de)
ES (1)	ES2261433T3 (de)
HR (1)	HRP20021003A2 (de)
HU (1)	HUP0301105A2 (de)
IL (1)	IL152819A0 (de)
MX (1)	MXPA02012205A (de)
MY (1)	MY130375A (de)
NO (1)	NO323830B1 (de)
NZ (1)	NZ523549A (de)
PE (1)	PE20020083A1 (de)
PL (1)	PL360370A1 (de)
PT (1)	PT1294720E (de)
SA (1)	SA01220202B1 (de)
SK (1)	SK17722002A3 (de)
TW (1)	TWI270547B (de)
UA (1)	UA74834C2 (de)
UY (1)	UY26767A1 (de)
WO (1)	WO2001096338A1 (de)
YU (1)	YU94202A (de)
ZA (1)	ZA200209807B (de)

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Publication number	Priority date	Publication date	Assignee	Title
US6716836B2 (en)	2001-03-22	2004-04-06	Boehringer Ingelheim (Canada) Ltd.	Non-nucleoside reverse transcriptase inhibitors
US6673791B2 (en) *	2001-07-30	2004-01-06	Boehringer Ingelheim (Canada) Ltd.	Non-nucleoside reverse transcriptase inhibitors
US6706706B2 (en) *	2002-03-27	2004-03-16	Boehringer Ingelheim International Gmbh	Non-nucleoside reverse transcriptase inhibitors
US6806265B2 (en) *	2002-05-16	2004-10-19	Boehringer Ingelheim International Gmbh	Non-nucleoside reverse transcriptase inhibitors
US6759533B2 (en) *	2002-06-28	2004-07-06	Boehringer Ingelheim Pharmaceuticals, Inc.	Process and intermediates for making non-nucleoside HIV-1 reverse transcriptase inhibitors
US7642277B2 (en)	2002-12-04	2010-01-05	Boehringer Ingelheim International Gmbh	Non-nucleoside reverse transcriptase inhibitors
US20040152625A1 (en) *	2002-12-16	2004-08-05	Boehringer Ingelheim International Gmbh	Method for improving the pharmacokinetics of an NNRTI
EP1610782A1 (de) *	2003-03-27	2006-01-04	Boehringer Ingelheim International GmbH	Antivirale kombination eines dipyridodiazepinons und einer weiteren antiretroviralen verbindung
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2001
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Also Published As

Publication number	Publication date
HRP20021003A2 (en)	2005-02-28
PL360370A1 (en)	2004-09-06
YU94202A (sh)	2005-11-28
PT1294720E (pt)	2006-06-30
JP2004502787A (ja)	2004-01-29
ES2261433T3 (es)	2006-11-16
BR0102377A (pt)	2002-02-19
HK1057558A1 (en)	2004-04-08
MY130375A (en)	2007-06-29
PE20020083A1 (es)	2002-02-28
NO20025844D0 (no)	2002-12-05
JP3923894B2 (ja)	2007-06-06
TWI270547B (en)	2007-01-11
NO20025844L (no)	2002-12-05
WO2001096338A1 (en)	2001-12-20
EA200201255A1 (ru)	2003-06-26
CN1436189A (zh)	2003-08-13
MXPA02012205A (es)	2003-09-10
AU7037001A (en)	2001-12-24
DK1294720T3 (da)	2006-07-31
CZ20024114A3 (cs)	2003-04-16
SK17722002A3 (sk)	2003-06-03
AR028958A1 (es)	2003-05-28
US6420359B1 (en)	2002-07-16
EP1294720A1 (de)	2003-03-26
UA74834C2 (en)	2006-02-15
BG107348A (bg)	2004-06-30
NZ523549A (en)	2004-08-27
EA005598B1 (ru)	2005-04-28
EP1294720B1 (de)	2006-04-05
CA2411766A1 (en)	2001-12-20
HUP0301105A2 (hu)	2003-08-28
CN1178939C (zh)	2004-12-08
NO323830B1 (no)	2007-07-09
US20020028807A1 (en)	2002-03-07
IL152819A0 (en)	2003-06-24
ATE322492T1 (de)	2006-04-15
DE60118560T2 (de)	2006-09-28
AU2001270370B2 (en)	2006-08-03
CA2411766C (en)	2006-05-23
DE60118560D1 (de)	2006-05-18
UY26767A1 (es)	2002-01-31
SA01220202B1 (ar)	2006-09-05
EE200200690A (et)	2004-06-15
KR20030017540A (ko)	2003-03-03

Publication	Publication Date	Title
EP1554276B1 (de)	2006-06-28	Nicht-nukleosidische inhibitoren der reverse transkriptase
US20040132723A1 (en)	2004-07-08	Non-nucleoside reverse transcriptase inhibitors
EP1506195B1 (de)	2008-10-29	Nicht-nukleosidische inhibitoren der reversen transkriptase
US6420359B1 (en)	2002-07-16	Non-nucleoside reverse transcriptase inhibitors
AU2001270370A1 (en)	2002-03-14	Non-nucleoside reverse transcriptase inhibitors
EP1414820B1 (de)	2008-02-13	Nicht-nucleosidische inhibitoren der reverse transkriptase
CA2479216C (en)	2009-08-18	Dipyridodiazepinones as reverse transcriptase inhibitors
EP1655300A1 (de)	2006-05-10	Nicht-nucleosidische Inhibitoren der reversen Transcriptase