HRP20021003A2 - Non-nucleoside reverse transcriptase inhibitors - Google Patents

Non-nucleoside reverse transcriptase inhibitors Download PDF

Info

Publication number
HRP20021003A2
HRP20021003A2 HR20021003A HRP20021003A HRP20021003A2 HR P20021003 A2 HRP20021003 A2 HR P20021003A2 HR 20021003 A HR20021003 A HR 20021003A HR P20021003 A HRP20021003 A HR P20021003A HR P20021003 A2 HRP20021003 A2 HR P20021003A2
Authority
HR
Croatia
Prior art keywords
mmol
solution
ethyl
dihydro
dipyrido
Prior art date
Application number
HR20021003A
Other languages
English (en)
Croatian (hr)
Inventor
Simoneau Bruno
Original Assignee
Boehringer Ingelheim (Canada) Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim (Canada) Ltd. filed Critical Boehringer Ingelheim (Canada) Ltd.
Publication of HRP20021003A2 publication Critical patent/HRP20021003A2/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
HR20021003A 2000-06-16 2001-06-14 Non-nucleoside reverse transcriptase inhibitors HRP20021003A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21232900P 2000-06-16 2000-06-16
US25663800P 2000-12-18 2000-12-18
PCT/CA2001/000890 WO2001096338A1 (en) 2000-06-16 2001-06-14 Non-nucleoside reverse transcriptase inhibitors

Publications (1)

Publication Number Publication Date
HRP20021003A2 true HRP20021003A2 (en) 2005-02-28

Family

ID=26907019

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20021003A HRP20021003A2 (en) 2000-06-16 2001-06-14 Non-nucleoside reverse transcriptase inhibitors

Country Status (35)

Country Link
US (1) US6420359B1 (de)
EP (1) EP1294720B1 (de)
JP (1) JP3923894B2 (de)
KR (1) KR20030017540A (de)
CN (1) CN1178939C (de)
AR (1) AR028958A1 (de)
AT (1) ATE322492T1 (de)
AU (2) AU7037001A (de)
BG (1) BG107348A (de)
BR (1) BR0102377A (de)
CA (1) CA2411766C (de)
CZ (1) CZ20024114A3 (de)
DE (1) DE60118560T2 (de)
DK (1) DK1294720T3 (de)
EA (1) EA005598B1 (de)
EE (1) EE200200690A (de)
ES (1) ES2261433T3 (de)
HR (1) HRP20021003A2 (de)
HU (1) HUP0301105A2 (de)
IL (1) IL152819A0 (de)
MX (1) MXPA02012205A (de)
MY (1) MY130375A (de)
NO (1) NO323830B1 (de)
NZ (1) NZ523549A (de)
PE (1) PE20020083A1 (de)
PL (1) PL360370A1 (de)
PT (1) PT1294720E (de)
SA (1) SA01220202B1 (de)
SK (1) SK17722002A3 (de)
TW (1) TWI270547B (de)
UA (1) UA74834C2 (de)
UY (1) UY26767A1 (de)
WO (1) WO2001096338A1 (de)
YU (1) YU94202A (de)
ZA (1) ZA200209807B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716836B2 (en) 2001-03-22 2004-04-06 Boehringer Ingelheim (Canada) Ltd. Non-nucleoside reverse transcriptase inhibitors
US6673791B2 (en) 2001-07-30 2004-01-06 Boehringer Ingelheim (Canada) Ltd. Non-nucleoside reverse transcriptase inhibitors
US6706706B2 (en) * 2002-03-27 2004-03-16 Boehringer Ingelheim International Gmbh Non-nucleoside reverse transcriptase inhibitors
US6806265B2 (en) * 2002-05-16 2004-10-19 Boehringer Ingelheim International Gmbh Non-nucleoside reverse transcriptase inhibitors
US6759533B2 (en) * 2002-06-28 2004-07-06 Boehringer Ingelheim Pharmaceuticals, Inc. Process and intermediates for making non-nucleoside HIV-1 reverse transcriptase inhibitors
US7642277B2 (en) 2002-12-04 2010-01-05 Boehringer Ingelheim International Gmbh Non-nucleoside reverse transcriptase inhibitors
WO2004054586A1 (en) * 2002-12-16 2004-07-01 Boehringer Ingelheim International Gmbh Use of a combination containing a non-nucleoside reverse transcriptase inhibitor (nnrti) with an inhibitor of cytochrome p450, such as protease inhibitors
EP1610782A1 (de) * 2003-03-27 2006-01-04 Boehringer Ingelheim International GmbH Antivirale kombination eines dipyridodiazepinons und einer weiteren antiretroviralen verbindung
US7309700B2 (en) * 2004-04-02 2007-12-18 Boehringer Ingelheim International Gmbh Crystalline forms of 5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-dipyrido[3,2-b:2′,3′-e] [1,4]diazepin-6-one
US20060025480A1 (en) 2004-08-02 2006-02-02 Boehringer Ingelheim International Gmbh Benzoic acid derivatives as non nucleoside reverse transcriptase inhibitors
US7151174B2 (en) * 2004-11-05 2006-12-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for making a non-nucleoside HIV-1 reverse transcriptase inhibitor
WO2007067844A1 (en) * 2005-12-05 2007-06-14 Boehringer Ingelheim International Gmbh Process for making 5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6h-di pyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
EP2085390A1 (de) 2008-01-31 2009-08-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Markierte Analoge von Halobenzamiden als multimodale Radiopharmazeutika und ihre Vorläufer
BRPI1014821A2 (pt) * 2009-04-09 2016-04-05 Boehringer Ingelheim Int "inibidores de replicação de hiv"

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
US5705499A (en) * 1995-10-06 1998-01-06 Boehringer Ingelheim Pharmaceuticals, Inc. 8-arylalkyl- and 8-arylheteroalkyl-5,11-dihydro-6H-dipyrido 3,2-B:2',3'-e! 1!diazepines and their use in the treatment of HIV-1 infection

Also Published As

Publication number Publication date
NO20025844D0 (no) 2002-12-05
ATE322492T1 (de) 2006-04-15
DE60118560T2 (de) 2006-09-28
JP2004502787A (ja) 2004-01-29
PE20020083A1 (es) 2002-02-28
BR0102377A (pt) 2002-02-19
TWI270547B (en) 2007-01-11
EA200201255A1 (ru) 2003-06-26
CA2411766A1 (en) 2001-12-20
IL152819A0 (en) 2003-06-24
PL360370A1 (en) 2004-09-06
CN1178939C (zh) 2004-12-08
AU2001270370B2 (en) 2006-08-03
KR20030017540A (ko) 2003-03-03
ZA200209807B (en) 2003-10-16
EE200200690A (et) 2004-06-15
DK1294720T3 (da) 2006-07-31
PT1294720E (pt) 2006-06-30
AR028958A1 (es) 2003-05-28
UY26767A1 (es) 2002-01-31
MXPA02012205A (es) 2003-09-10
NO20025844L (no) 2002-12-05
NZ523549A (en) 2004-08-27
EA005598B1 (ru) 2005-04-28
EP1294720A1 (de) 2003-03-26
HUP0301105A2 (hu) 2003-08-28
AU7037001A (en) 2001-12-24
CZ20024114A3 (cs) 2003-04-16
MY130375A (en) 2007-06-29
CN1436189A (zh) 2003-08-13
WO2001096338A1 (en) 2001-12-20
CA2411766C (en) 2006-05-23
US6420359B1 (en) 2002-07-16
JP3923894B2 (ja) 2007-06-06
US20020028807A1 (en) 2002-03-07
YU94202A (sh) 2005-11-28
EP1294720B1 (de) 2006-04-05
HK1057558A1 (en) 2004-04-08
DE60118560D1 (de) 2006-05-18
UA74834C2 (en) 2006-02-15
SK17722002A3 (sk) 2003-06-03
ES2261433T3 (es) 2006-11-16
BG107348A (bg) 2004-06-30
NO323830B1 (no) 2007-07-09
SA01220202B1 (ar) 2006-09-05

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
OBST Application withdrawn