ZA200506708B - Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter - Google Patents

Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter Download PDF

Info

Publication number: ZA200506708B
Authority: ZA; South Africa
Prior art keywords: agonists; compound; inhibitors; compounds; medicament
Prior art date: 2003-04-01

Application number

ZA200506708A

Other languages

English (en)

Inventor

Jaehne Gerhard

Lindenschmidt Andreas

Heuer Hubert

Kramer Werner

Glombik Heiner

Frick Wendelin

Flohr Stefanie

Schaefer Hans-Ludwig

Galia Eric

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-01

Filing date

2005-08-22

Publication date

2007-01-31

2005-08-22 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2007-01-31 Publication of ZA200506708B publication Critical patent/ZA200506708B/en

Links

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VDOXIAUNJCHYRC-UHFFFAOYSA-N 1,3-diphenylazetidin-2-one Chemical compound O=C1C(C=2C=CC=CC=2)CN1C1=CC=CC=C1 VDOXIAUNJCHYRC-UHFFFAOYSA-N 0.000 title description 4
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Classifications

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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Diabetes (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
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Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ZA200506708A 2003-04-01 2005-08-22 Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter ZA200506708B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10314610A DE10314610A1 (de)	2003-04-01	2003-04-01	Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung

Publications (1)

Publication Number	Publication Date
ZA200506708B true ZA200506708B (en)	2007-01-31

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ZA200506708A ZA200506708B (en)	2003-04-01	2005-08-22	Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter

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US (2)	US7205290B2 (sr)
EP (2)	EP1613589B1 (sr)
JP (1)	JP2006522040A (sr)
KR (1)	KR20050119180A (sr)
CN (2)	CN100361970C (sr)
AR (1)	AR043783A1 (sr)
AT (2)	ATE386020T1 (sr)
AU (1)	AU2004226287B2 (sr)
BR (1)	BRPI0408920A (sr)
CA (1)	CA2520689A1 (sr)
CL (1)	CL43489B (sr)
CR (1)	CR7995A (sr)
CY (2)	CY1107398T1 (sr)
DE (3)	DE10314610A1 (sr)
DK (2)	DK1613589T3 (sr)
EC (1)	ECSP056071A (sr)
ES (2)	ES2298731T3 (sr)
GT (1)	GT200400058A (sr)
HN (1)	HN2004000109A (sr)
HR (1)	HRP20050870A2 (sr)
JO (1)	JO2493B1 (sr)
MA (1)	MA27753A1 (sr)
ME (1)	MEP41408A (sr)
MX (1)	MXPA05010128A (sr)
MY (1)	MY136269A (sr)
NI (1)	NI200500164A (sr)
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NZ (1)	NZ542751A (sr)
PA (1)	PA8599401A1 (sr)
PE (1)	PE20050011A1 (sr)
PL (2)	PL1862455T3 (sr)
PT (2)	PT1613589E (sr)
RS (1)	RS51146B (sr)
RU (1)	RU2334737C2 (sr)
SA (1)	SA04250154B1 (sr)
SI (2)	SI1862455T1 (sr)
SV (1)	SV2004001756A (sr)
TN (1)	TNSN05244A1 (sr)
TW (1)	TW200504009A (sr)
UA (1)	UA80754C2 (sr)
UY (1)	UY28253A1 (sr)
WO (1)	WO2004087655A1 (sr)
ZA (1)	ZA200506708B (sr)

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WO2012120051A1 (de)	2011-03-08	2012-09-13	Sanofi	Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
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2003
- 2003-04-01 DE DE10314610A patent/DE10314610A1/de not_active Withdrawn
2004
- 2004-02-24 JO JO200418A patent/JO2493B1/en active
- 2004-03-16 ES ES04720854T patent/ES2298731T3/es not_active Expired - Lifetime
- 2004-03-16 CN CNB2004800084976A patent/CN100361970C/zh not_active Expired - Fee Related
- 2004-03-16 PT PT04720854T patent/PT1613589E/pt unknown
- 2004-03-16 JP JP2006504695A patent/JP2006522040A/ja active Pending
- 2004-03-16 AU AU2004226287A patent/AU2004226287B2/en not_active Ceased
- 2004-03-16 PL PL07016889T patent/PL1862455T3/pl unknown
- 2004-03-16 DK DK04720854T patent/DK1613589T3/da active
- 2004-03-16 DE DE502004009059T patent/DE502004009059D1/de not_active Expired - Lifetime
- 2004-03-16 ME MEP-414/08A patent/MEP41408A/xx unknown
- 2004-03-16 CA CA002520689A patent/CA2520689A1/en not_active Abandoned
- 2004-03-16 BR BRPI0408920-0A patent/BRPI0408920A/pt not_active IP Right Cessation
- 2004-03-16 DE DE502004006195T patent/DE502004006195D1/de not_active Expired - Lifetime
- 2004-03-16 RS YUP-2005/0719A patent/RS51146B/sr unknown
- 2004-03-16 CN CNA2007101491852A patent/CN101139306A/zh active Pending
- 2004-03-16 WO PCT/EP2004/002690 patent/WO2004087655A1/de not_active Ceased
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- 2004-03-16 RU RU2005133631/04A patent/RU2334737C2/ru not_active IP Right Cessation
- 2004-03-16 ES ES07016889T patent/ES2322876T3/es not_active Expired - Lifetime
- 2004-03-16 SI SI200430681T patent/SI1613589T1/sl unknown
- 2004-03-16 AT AT04720854T patent/ATE386020T1/de not_active IP Right Cessation
- 2004-03-16 UA UAA200510204A patent/UA80754C2/uk unknown
- 2004-03-16 NZ NZ542751A patent/NZ542751A/en unknown
- 2004-03-16 PT PT07016889T patent/PT1862455E/pt unknown
- 2004-03-16 HR HR20050870A patent/HRP20050870A2/xx not_active Application Discontinuation
- 2004-03-16 KR KR1020057018705A patent/KR20050119180A/ko not_active Ceased
- 2004-03-16 EP EP04720854A patent/EP1613589B1/de not_active Expired - Lifetime
- 2004-03-16 AT AT07016889T patent/ATE423766T1/de not_active IP Right Cessation
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- 2004-03-16 DK DK07016889T patent/DK1862455T3/da active
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- 2004-03-31 SV SV2004001756A patent/SV2004001756A/es not_active Application Discontinuation
- 2004-03-31 US US10/813,954 patent/US7205290B2/en not_active Expired - Fee Related
- 2004-04-01 CL CL200400708A patent/CL43489B/es active
- 2004-06-09 SA SA04250154A patent/SA04250154B1/ar unknown
2005
- 2005-08-22 ZA ZA200506708A patent/ZA200506708B/en unknown
- 2005-09-19 CR CR7995A patent/CR7995A/es unknown
- 2005-09-22 NI NI200500164A patent/NI200500164A/es unknown
- 2005-09-30 MA MA28529A patent/MA27753A1/fr unknown
- 2005-09-30 EC EC2005006071A patent/ECSP056071A/es unknown
- 2005-09-30 TN TNP2005000244A patent/TNSN05244A1/en unknown
- 2005-10-27 NO NO20055001A patent/NO20055001L/no not_active Application Discontinuation
2007
- 2007-03-26 US US11/690,993 patent/US7772429B2/en not_active Expired - Fee Related
2008
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Also Published As

Publication number	Publication date
SI1862455T1 (sl)	2009-06-30
PT1862455E (pt)	2009-04-23
CY1109055T1 (el)	2014-07-02
TW200504009A (en)	2005-02-01
PA8599401A1 (es)	2004-10-08
TNSN05244A1 (en)	2007-06-11
AU2004226287A1 (en)	2004-10-14
US7772429B2 (en)	2010-08-10
GT200400058A (es)	2004-11-10
JP2006522040A (ja)	2006-09-28
EP1613589B1 (de)	2008-02-13
KR20050119180A (ko)	2005-12-20
AU2004226287B2 (en)	2010-03-18
MXPA05010128A (es)	2005-11-16
CN101139306A (zh)	2008-03-12
SA04250154B1 (ar)	2007-10-29
ES2298731T3 (es)	2008-05-16
PL1862455T3 (pl)	2009-07-31
CN1768034A (zh)	2006-05-03
WO2004087655A1 (de)	2004-10-14
RU2005133631A (ru)	2006-03-10
DK1862455T3 (da)	2009-06-02
US20050020563A1 (en)	2005-01-27
US7205290B2 (en)	2007-04-17
PT1613589E (pt)	2008-03-27
BRPI0408920A (pt)	2006-03-28
NI200500164A (es)	2006-01-11
DK1613589T3 (da)	2008-06-09
RS20050719A (sr)	2008-04-04
MA27753A1 (fr)	2006-02-01
EP1862455B1 (de)	2009-02-25
EP1862455A3 (de)	2007-12-12
ATE386020T1 (de)	2008-03-15
RS51146B (sr)	2010-10-31
DE502004006195D1 (de)	2008-03-27
CA2520689A1 (en)	2004-10-14
HRP20050870A2 (en)	2006-10-31
CL43489B (es)	2005-01-21
PE20050011A1 (es)	2005-02-28
SV2004001756A (es)	2004-11-18
SI1613589T1 (sl)	2008-06-30
NZ542751A (en)	2007-05-31
DE502004009059D1 (de)	2009-04-09
MEP41408A (en)	2011-02-10
UA80754C2 (en)	2007-10-25
ATE423766T1 (de)	2009-03-15
JO2493B1 (en)	2009-10-05
MY136269A (en)	2008-09-30
RU2334737C2 (ru)	2008-09-27
HK1087697A1 (zh)	2006-10-20
PL1613589T3 (pl)	2008-07-31
US20070197498A1 (en)	2007-08-23
ECSP056071A (es)	2006-01-27
EP1862455A2 (de)	2007-12-05
HN2004000109A (es)	2008-02-21
EP1613589A1 (de)	2006-01-11
CN100361970C (zh)	2008-01-16
CY1107398T1 (el)	2012-12-19
CR7995A (es)	2006-09-22
ES2322876T3 (es)	2009-06-30
UY28253A1 (es)	2004-11-08
NO20055001L (no)	2005-10-27
DE10314610A1 (de)	2004-11-04
AR043783A1 (es)	2005-08-10

Publication	Publication Date	Title
US7772429B2 (en)	2010-08-10	Diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use
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US20080207592A1 (en)	2008-08-28	Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof
JP4328212B2 (ja)	2009-09-09	アシル−３−カルボキシフェニル尿素誘導体、その製造方法およびその使用
CN1910182A (zh)	2007-02-07	环烷基取代的7－氨基－4－喹诺酮－3－甲酸衍生物、其制备方法及其作为药物的用途
US20040266768A1 (en)	2004-12-30	Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use
US7470706B2 (en)	2008-12-30	Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
JP2006502206A (ja)	2006-01-19	カルボキシアルコキシ置換アシル−カルボキシフェニル尿素誘導体、その製造方法、および医薬品としてのその使用
HK1115861A (en)	2008-12-12	Novel diphenyl azetidinone with improved physiological charateristics, corresponding production method, medicaments containing said compound and use of the latter
HK1087697B (en)	2008-05-02	Novel diphenyl azetidinone with improved physiological characteristics, corresponding production method, medicaments containing said compound and use of the latter
HK1123034A (en)	2009-06-05	1,4-benzothiazepine 1,1-dioxide derivative, process for its preparation, medicaments comprising this compound, and use thereof as a hypolipidaemic
HK1122280A (en)	2009-05-15	Novel 1,4-benzothiazepine-1,1-dioxide derivative having improved properties, method for the production thereof, medicaments containing said compound, and use thereof
HK1087113A (en)	2006-10-06	Substituted benzoylureidopyridyl-piperidine and -pyrrolidine carboxylic acid derivatives, method for the production thereof and the use thereof