ZA200900165B - 4-amino-3-arylamino-6-arylpyrazolo[3,4-D]pyrimidine derivatives, methods for their preparation and their use as antiviral agents - Google Patents

4-amino-3-arylamino-6-arylpyrazolo[3,4-D]pyrimidine derivatives, methods for their preparation and their use as antiviral agents

Info

Publication number
ZA200900165B
ZA200900165B ZA200900165A ZA200900165A ZA200900165B ZA 200900165 B ZA200900165 B ZA 200900165B ZA 200900165 A ZA200900165 A ZA 200900165A ZA 200900165 A ZA200900165 A ZA 200900165A ZA 200900165 B ZA200900165 B ZA 200900165B
Authority
ZA
South Africa
Prior art keywords
arylpyrazolo
arylamino
amino
preparation
antiviral agents
Prior art date
Application number
ZA200900165A
Other languages
English (en)
Inventor
Vadim Makarov
Peter Wutzler
Michaela Schmidtke
Hans-Martin Dahse
Original Assignee
Dritte Patentportfolio Beteili
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dritte Patentportfolio Beteili filed Critical Dritte Patentportfolio Beteili
Publication of ZA200900165B publication Critical patent/ZA200900165B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200900165A 2006-06-22 2009-01-08 4-amino-3-arylamino-6-arylpyrazolo[3,4-D]pyrimidine derivatives, methods for their preparation and their use as antiviral agents ZA200900165B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102006029074A DE102006029074A1 (de) 2006-06-22 2006-06-22 4-Amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidin-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung als antivirale Wirkstoffe

Publications (1)

Publication Number Publication Date
ZA200900165B true ZA200900165B (en) 2009-12-30

Family

ID=38606873

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200900165A ZA200900165B (en) 2006-06-22 2009-01-08 4-amino-3-arylamino-6-arylpyrazolo[3,4-D]pyrimidine derivatives, methods for their preparation and their use as antiviral agents

Country Status (18)

Country Link
US (1) US8962634B2 (pt)
EP (1) EP2049540B1 (pt)
JP (1) JP5171815B2 (pt)
KR (1) KR101107839B1 (pt)
CN (1) CN101553489B (pt)
AT (1) ATE492548T1 (pt)
AU (1) AU2007262524B2 (pt)
BR (1) BRPI0713488B1 (pt)
CA (1) CA2655754C (pt)
DE (2) DE102006029074A1 (pt)
ES (1) ES2359677T3 (pt)
IL (1) IL195837A0 (pt)
NO (1) NO20090332L (pt)
NZ (1) NZ573849A (pt)
RU (1) RU2456288C2 (pt)
SG (1) SG173316A1 (pt)
WO (1) WO2007147401A1 (pt)
ZA (1) ZA200900165B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA121539C2 (uk) * 2011-09-02 2020-06-25 Інсайт Холдинґс Корпорейшн Гетероцикліламіни як інгібітори рі3к
DE102011116373A1 (de) 2011-10-14 2013-04-18 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg Methode zur Herstellung von 4-Amino-3-arylamino-6-arylpyrazolo[3, 4-d]pyrimidinen
PT2766367T (pt) 2011-10-14 2022-08-12 Scandion Oncology As Derivados de 4-amino-3-fenilamino-6-fenilpirazolo[3,4-d]pirimidina para o tratamento de infeções virais, em particular infeções por picornavírus
DE102012004736A1 (de) 2011-10-20 2013-04-25 Dritte Patentportfolio Beteiligungsgesellschaft Mbh & Co.Kg 4-Amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidin-Derivate und deren Verwendung als antivirale Wirkstoffe
WO2016044656A1 (en) 2014-09-17 2016-03-24 Ansun Biopharma, Inc. Treatment of infection by human enterovirus d68
EP3064207B1 (en) 2015-03-04 2017-12-20 Scandion Oncology A/S 4-amino-3-phenylamino-6-phenylpyrazolo[3,4-d]pyrimidine derivatives for use as BCRP inhibitors in therapeutic treatments

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2965643A (en) * 1960-12-20 Derivatives of pyrazolo
US3551428A (en) * 1956-02-10 1970-12-29 Ciba Geigy Corp New 1- (or 2-) substituted 4-mercapto-pyrazolo(3,4-d)pyrimidines
DE1088503B (de) * 1957-12-06 1960-09-08 Ciba Geigy Verfahren zur Herstellung von 3-Amino-pyrazolo-[3,4-d]-pyrimidinen
DE3712735A1 (de) * 1987-04-15 1988-11-10 Boehringer Mannheim Gmbh Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel
FI933303L (fi) 1991-01-23 1993-08-31 Gensia Inc Adenosinkinasinhibitorer
US5294612A (en) * 1992-03-30 1994-03-15 Sterling Winthrop Inc. 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
TW444018B (en) 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
US5646152A (en) 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
CZ27399A3 (cs) * 1999-01-26 2000-08-16 Ústav Experimentální Botaniky Av Čr Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
KR100844864B1 (ko) * 2004-02-27 2008-07-09 에프. 호프만-라 로슈 아게 헤테로아릴-융합 피라졸로 유도체
AP2007003923A0 (en) * 2004-09-30 2007-02-28 Tibotec Pharm Ltd Hcv inhibiting bi-cyclic pyrimidines

Also Published As

Publication number Publication date
CN101553489A (zh) 2009-10-07
NO20090332L (no) 2009-03-12
IL195837A0 (en) 2009-09-01
ES2359677T3 (es) 2011-05-25
BRPI0713488B1 (pt) 2022-04-12
US8962634B2 (en) 2015-02-24
EP2049540B1 (de) 2010-12-22
WO2007147401A1 (de) 2007-12-27
RU2456288C2 (ru) 2012-07-20
JP5171815B2 (ja) 2013-03-27
CA2655754A1 (en) 2007-12-27
DE502007006042D1 (de) 2011-02-03
KR101107839B1 (ko) 2012-02-09
US20100010018A1 (en) 2010-01-14
DE102006029074A1 (de) 2007-12-27
AU2007262524B2 (en) 2011-12-01
SG173316A1 (en) 2011-08-29
AU2007262524A1 (en) 2007-12-27
KR20090071536A (ko) 2009-07-01
JP2009541230A (ja) 2009-11-26
NZ573849A (en) 2011-11-25
CN101553489B (zh) 2013-07-17
EP2049540A1 (de) 2009-04-22
CA2655754C (en) 2012-02-07
RU2009101920A (ru) 2010-07-27
ATE492548T1 (de) 2011-01-15
BRPI0713488A2 (pt) 2012-10-23

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