ZA858986B - Porphyrins and cancer treatment - Google Patents

Porphyrins and cancer treatment

Info

Publication number
ZA858986B
ZA858986B ZA858986A ZA858986A ZA858986B ZA 858986 B ZA858986 B ZA 858986B ZA 858986 A ZA858986 A ZA 858986A ZA 858986 A ZA858986 A ZA 858986A ZA 858986 B ZA858986 B ZA 858986B
Authority
ZA
South Africa
Prior art keywords
porphyrins
meso
same
cancer treatment
compound
Prior art date
Application number
ZA858986A
Other languages
English (en)
Original Assignee
Efamol Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Efamol Ltd filed Critical Efamol Ltd
Publication of ZA858986B publication Critical patent/ZA858986B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA858986A 1984-11-26 1985-11-25 Porphyrins and cancer treatment ZA858986B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848429845A GB8429845D0 (en) 1984-11-26 1984-11-26 Porphyrins & cancer treatment

Publications (1)

Publication Number Publication Date
ZA858986B true ZA858986B (en) 1986-08-27

Family

ID=10570288

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA858986A ZA858986B (en) 1984-11-26 1985-11-25 Porphyrins and cancer treatment

Country Status (11)

Country Link
US (1) US4837221A (de)
EP (1) EP0186962B1 (de)
JP (1) JPH0653665B2 (de)
AT (1) ATE42037T1 (de)
AU (1) AU578329B2 (de)
CA (1) CA1257202A (de)
DE (1) DE3569332D1 (de)
GB (1) GB8429845D0 (de)
HK (1) HK132493A (de)
IE (1) IE58500B1 (de)
ZA (1) ZA858986B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066274A (en) * 1985-04-30 1991-11-19 Nippon Petrochemicals Company, Ltd. Tetrapyrrole therapeutic agents
GB8522670D0 (en) * 1985-09-13 1985-10-16 Efamol Ltd Drug treatments
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
JPH0629196B2 (ja) * 1987-12-01 1994-04-20 甲子郎 梅村 超音波による腫瘍治療用生理作用増強剤
GB8805849D0 (en) * 1988-03-11 1988-04-13 Efamol Holdings Porphyrins & cancer treatment
DE3809671A1 (de) * 1988-03-18 1989-09-28 Schering Ag Porphyrin-komplexverbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
JPH01242584A (ja) * 1988-03-24 1989-09-27 Yoshio Imai 芳香族ジアミン
FR2632187B1 (fr) * 1988-06-02 1990-09-14 Centre Nat Rech Scient Derives de metalloporphyrines, leur preparation, leur application en therapeutique et leur utilisation pour la preparation de molecules hybrides
FR2656866B1 (fr) * 1990-01-10 1992-05-15 Cis Bio Int Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant.
US5219878A (en) * 1990-10-05 1993-06-15 Queen's University Tetrapyrrole hydroxyalkylamide photochemotherapeutic agents
PL165249B1 (pl) * 1991-10-29 1994-11-30 Wojskowa Akad Tech Sposób otrzymywania soli kompleksowych hematoporfiryny i jej pochodnych PL PL PL PL PL PL PL
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
GB9408746D0 (en) * 1994-05-03 1994-06-22 Scotia Holdings Plc Tumour locallising photosensitising compounds
WO1996009053A1 (en) * 1994-09-20 1996-03-28 Duke University Oxidoreductase activity of manganic porphyrins
JPH11509180A (ja) * 1995-06-07 1999-08-17 デューク・ユニバーシティ 酸化体脱除剤
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
JP2001521939A (ja) 1997-11-03 2001-11-13 デューク・ユニバーシティー 置換されたポルフィリン類
DE69928655T2 (de) 1998-04-24 2006-08-24 Duke University Substituierte porphyrine
AU765509B2 (en) * 1998-08-28 2003-09-18 Destiny Pharma Limited Porphyrin derivatives, their use in photodynamic therapy and medical devices containing them
EP1155019B1 (de) 1999-01-25 2005-12-07 National Jewish Medical and Research Center Substituierte porphyrine und deren therapeutische verwendungen
GB0001455D0 (en) * 2000-01-21 2000-03-15 Scotia Holdings Plc Porphyrins and related compounds
JP2004501923A (ja) * 2000-06-26 2004-01-22 カタリスト　　バイオメディカ　リミテッド 発色団の改善及び発色団に関する改善
KR100390771B1 (ko) * 2000-08-31 2003-07-10 한국화학연구원 광역학 치료(ｐｄｔ)용 광민감성 물질로 유용한 포르피린유도체
JP2004520380A (ja) * 2001-01-19 2004-07-08 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 癌治療本出願は、２００１年１月１９日に出願の仮出願番号第６０／２６２，３９０号の優先権を主張し、その全ての内容は、参照により本願明細書に援用したものとする。
JP2005508864A (ja) 2001-06-01 2005-04-07 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー
JP4529344B2 (ja) * 2002-06-03 2010-08-25 ニプロ株式会社 腫瘍組織の酸素濃度を上昇させるためのポルフィリン酸素輸液製剤
EP1513537A4 (de) 2002-06-07 2006-09-06 Univ Duke Substituierte porphyrine
US11382895B2 (en) 2008-05-23 2022-07-12 National Jewish Health Methods for treating injury associated with exposure to an alkylating species
EP2230242B1 (de) 2009-03-16 2013-08-14 Johannes Kepler Universität Synthese von neuen asymmetrisch mesosubstituierten wasserlöslichen, als zytostatische Mittel wirkenden Porphyrinen
WO2011161065A1 (en) 2010-06-25 2011-12-29 Fundação Padre Antonio Vieira Macrocyclic tetrapyrrolic compound of the family of porphyrins, chlorins and bacteriochlorins as photosensitizers for photodynamic therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988436A (en) * 1974-02-11 1976-10-26 Carnation Company Sunscreening method using rice bran oil
US4393071A (en) * 1975-03-17 1983-07-12 Naoharu Fujii Method of treating gastric, mammary, lung and uterus tumors
JPS5587792A (en) * 1978-12-27 1980-07-02 Green Cross Corp:The Meso-tetra(p-carboxyphenyl)porphine derivative
JPS5587793A (en) * 1978-12-27 1980-07-02 Green Cross Corp:The Carcinostatic meso-tetra(p-carboxyphenyl)porphine derivative
JPS5787793A (en) * 1980-11-19 1982-06-01 Mitsubishi Heavy Ind Ltd Hydraulic steering apparatus for vessel
US4386087A (en) * 1981-07-01 1983-05-31 Research Foundation Of The City University Of New York N-Substituted metalloporphyrins as anti-tumor agents against PS-P-388(P388) leukemia in animals
JPH0249315B2 (ja) * 1981-08-17 1990-10-29 Seisan Kaihatsu Kagaku Kenkyusho Sosuiseichikankiojusuruhorufuirinoyobisonosakutai
AU549719B2 (en) * 1981-09-08 1986-02-06 Metalaser Technologies Limited Photoradiation method and arrangement
US4656186A (en) * 1985-04-30 1987-04-07 Nippon Petrochemicals Co., Ltd. Tetrapyrrole therapeutic agents

Also Published As

Publication number Publication date
IE852906L (en) 1986-05-26
HK132493A (en) 1993-12-10
AU5036785A (en) 1986-06-05
JPS61130220A (ja) 1986-06-18
JPH0653665B2 (ja) 1994-07-20
IE58500B1 (en) 1993-10-06
AU578329B2 (en) 1988-10-20
CA1257202A (en) 1989-07-11
GB8429845D0 (en) 1985-01-03
EP0186962A1 (de) 1986-07-09
EP0186962B1 (de) 1989-04-12
ATE42037T1 (de) 1989-04-15
DE3569332D1 (en) 1989-05-18
US4837221A (en) 1989-06-06

Similar Documents

Publication Publication Date Title
DE3569332D1 (en) Porphyrins and cancer treatment
GB8805849D0 (en) Porphyrins & cancer treatment
GR3017282T3 (en) Novel arylpyridazines, their manufacture, use and medicaments containing them.
BR9205645A (pt) Derivados de 2,4-diaminoquinazolinas para aumentar a atividade antitumoral
IN170909B (de)
GEP20001917B (en) Macrolidal Antibiotic.
NO882785D0 (no) Heksacyklisk forbindelse.
HU911193D0 (en) Conjugates consisting of difluor-glutaminic acid and pholates as well as antipholates being suitable for treating pneosplastic illnesses
EP0424156A3 (en) Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
EP0333831A4 (de) Verwendung von metalloporphyrin zur umkehr des toxischen effekts der tumortherapie.
AU639804B2 (en) Novel platinum (ii) complex and drug for treating malignant tumor
DK0378146T3 (da) Polyamin-derivater som antineoplastiske midler
ATE88176T1 (de) 2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
IL98200A0 (en) Pharmaceutical composition containing a derivative of substituted-l-valyl-l-prolinamide
MX9706283A (es) Nuevos antibioticos de polieno, 3874 hi a h6, procedimientos para su preparacion y empleo.
TW228524B (de)
MX9102181A (es) Iminobenzodiazepina para el tratamiento de desordenes del sueno
NZ336321A (en) Use of benzothiophene (raloxifene) for treating breast cancer