ZA876970B - Assay method and diagnostic system for a marker of abnormal lipid metabolism - Google Patents

Assay method and diagnostic system for a marker of abnormal lipid metabolism

Info

Publication number
ZA876970B
ZA876970B ZA876970A ZA876970A ZA876970B ZA 876970 B ZA876970 B ZA 876970B ZA 876970 A ZA876970 A ZA 876970A ZA 876970 A ZA876970 A ZA 876970A ZA 876970 B ZA876970 B ZA 876970B
Authority
ZA
South Africa
Prior art keywords
marker
assay method
diagnostic system
lipid metabolism
abnormal lipid
Prior art date
Application number
ZA876970A
Other languages
English (en)
Inventor
S. Smith Richard
M. Hogle Doreen
K. Curtiss Linda
L. Witztum Joseph
Young Steven
Original Assignee
Scripps Clinic And Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic And Research Foundation filed Critical Scripps Clinic And Research Foundation
Publication of ZA876970B publication Critical patent/ZA876970B/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Fats And Perfumes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Arrangements For Transmission Of Measured Signals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA876970A 1986-09-29 1987-09-16 Assay method and diagnostic system for a marker of abnormal lipid metabolism ZA876970B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/913,140 US4828986A (en) 1986-09-29 1986-09-29 Assay method and diagnostic system for determining the ratio of APO B-100 to APO A-I in a blood sample

Publications (1)

Publication Number Publication Date
ZA876970B true ZA876970B (en) 1988-03-21

Family

ID=25432962

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA876970A ZA876970B (en) 1986-09-29 1987-09-16 Assay method and diagnostic system for a marker of abnormal lipid metabolism

Country Status (17)

Country Link
US (1) US4828986A (da)
EP (1) EP0262854B1 (da)
JP (1) JP2656774B2 (da)
AT (1) ATE85435T1 (da)
AU (1) AU611096B2 (da)
CA (1) CA1285869C (da)
DE (1) DE3783991T2 (da)
DK (1) DK173724B1 (da)
ES (1) ES2053555T3 (da)
FI (1) FI89214C (da)
GR (1) GR3008027T3 (da)
IE (1) IE60119B1 (da)
IL (1) IL83938A (da)
NO (1) NO173902C (da)
NZ (1) NZ221941A (da)
PT (1) PT85827B (da)
ZA (1) ZA876970B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE120233T1 (de) * 1986-08-06 1995-04-15 Scripps Clinic Res Monoklonale antikörper, b-spezifisch für apolipoprotein, die von zwei hybridomen erzeugt werden.
DE3734015A1 (de) * 1987-10-08 1989-04-20 Behringwerke Ag Diagnostisches mittel und verfahren zur bestimmung von apolipoprotein b
AU621575B2 (en) * 1987-11-02 1992-03-19 Scripps Clinic And Research Foundation Diagnostic methods and systems for quantifying apo ai
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5183738A (en) * 1988-09-29 1993-02-02 Japan Immuno Research Laboratories Co., Ltd. Kit for the detection of denatured lipoproteins
US5179008A (en) * 1989-02-09 1993-01-12 Wisconsin Alumni Research Foundation Hybridoma and monoclonal antibody to FHAP
US5168045A (en) * 1989-08-18 1992-12-01 The Scripps Research Institute Diagnostic systems and methods using polypeptide analogs of apolipoprotein e
US5473039A (en) * 1989-08-18 1995-12-05 The Scripps Research Institute Polypeptide analogs of apolipoprotein E, diagnostic systems and methods using the analogs
AU662885B2 (en) * 1990-06-07 1995-09-21 Scripps Research Institute, The APO AI polypeptides, antibodies, and immunoassays
AU9088891A (en) * 1990-11-29 1992-06-25 John E. Carbaugh Diagnostic and therapeutic compositions and methods for lipoprotein(a)
US5844097A (en) * 1990-11-30 1998-12-01 Monoclonetics International, Inc. Methods for the diagnosis of peripheral nerve damage
AU667462B2 (en) * 1990-11-30 1996-03-28 Monoclonetics International Incorporated Methods for the diagnosis of chronic lower back and cervical pain
US5408038A (en) * 1991-10-09 1995-04-18 The Scripps Research Institute Nonnatural apolipoprotein B-100 peptides and apolipoprotein B-100-apolipoprotein A-I fusion peptides
JPH08501633A (ja) * 1992-09-24 1996-02-20 パーセプティブ バイオシステムズ インコーポレイテッド Ｌｄｌの定量
US6107045A (en) * 1994-06-30 2000-08-22 Oklahoma Medical Research Foundation Antibodies to lipoproteins and apolipoproteins and methods of use thereof
US5994061A (en) * 1995-09-29 1999-11-30 Queen's University At Kingston DNA constructs and methods for screening for increased expression of human apo AI gene
US5741647A (en) * 1996-02-16 1998-04-21 Tam; Joseph Wing On Flow through nucleic acid hybridisation uses thereof and a device thereof
US6248539B1 (en) 1997-09-05 2001-06-19 The Scripps Research Institute Porous semiconductor-based optical interferometric sensor
EP0911344B1 (en) * 1997-10-15 2004-03-03 Fujirebio Inc. Anti-Apo-B-48 monoclonal antibody, hybridoma, and methods of use
AT5044U1 (de) * 2001-05-10 2002-02-25 Medsystems Diagnostics Gmbh Quantitativer einschritt immuntest in lyophilisierter form
WO2003006989A1 (fr) * 2001-07-12 2003-01-23 Kyowa Medex Co., Ltd. Procede de quantification de lipoproteines denaturees, reactifs pour la quantification de lipoproteines denaturees, procede de detection de maladies du systeme circulatoire et reactifs pour la detection de maladies du systeme circulatoire
CN1864067B (zh) * 2003-10-15 2011-07-06 积水医疗株式会社 试样的前处理方法及使用该方法的免疫学测定方法
US7781171B2 (en) 2003-10-15 2010-08-24 Daiichi Pure Chemicals Co., Ltd. Mehod of pretreating sample and immunological assay method using the same
US7521248B2 (en) * 2007-04-20 2009-04-21 Atherotech, Inc. Apo B measurement system and method
CN110042146B (zh) 2011-11-11 2023-09-01 雅培快速诊断国际无限公司 血样本的化验方法
CN118047854B (zh) * 2024-02-26 2024-08-02 武汉鹰达生物科技有限公司 一种人载脂蛋白a-i的分离纯化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2061282B (en) * 1979-10-22 1983-03-30 Symphar Sa Method for the clinical separation of a-and lipoproteins and kit for carrying out this method
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
JPS60193926A (ja) * 1984-03-15 1985-10-02 Tokyo Daigaku 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体
JPS60253871A (ja) * 1984-05-30 1985-12-14 Nippon Koutai Kenkyusho:Kk 抗アポａ−１抗体
WO1986004144A1 (en) * 1984-12-31 1986-07-17 International Genetic Engineering, Inc. Peptide fragments of human apolipoprotein, type-specific antibodies and methods of use
US4677057A (en) * 1985-03-11 1987-06-30 Scripps Clinic And Research Foundation Diagnostic assay for the presence of apolipoproteins associated with plasma high density lipoproteins

Also Published As

Publication number Publication date
IL83938A (en) 1991-12-15
PT85827A (en) 1987-10-01
JP2656774B2 (ja) 1997-09-24
IE872605L (en) 1988-03-29
DE3783991D1 (de) 1993-03-18
PT85827B (pt) 1990-08-31
US4828986A (en) 1989-05-09
NZ221941A (en) 1989-05-29
FI89214B (fi) 1993-05-14
FI874253A0 (fi) 1987-09-28
EP0262854B1 (en) 1993-02-03
ES2053555T3 (es) 1994-08-01
NO874056D0 (no) 1987-09-28
FI874253L (fi) 1988-03-30
IE60119B1 (en) 1994-06-01
JPS63277968A (ja) 1988-11-15
DK509287A (da) 1988-03-30
FI89214C (fi) 1993-08-25
NO173902C (no) 1994-02-16
NO173902B (no) 1993-11-08
DK173724B1 (da) 2001-07-30
AU7902887A (en) 1988-03-31
NO874056L (no) 1988-03-30
AU611096B2 (en) 1991-06-06
EP0262854A3 (en) 1989-12-06
CA1285869C (en) 1991-07-09
IL83938A0 (en) 1988-02-29
ATE85435T1 (de) 1993-02-15
DE3783991T2 (de) 1993-06-09
EP0262854A2 (en) 1988-04-06
DK509287D0 (da) 1987-09-28
GR3008027T3 (da) 1993-09-30

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