ZA897660B - Biologically active compounds - Google Patents

Biologically active compounds

Info

Publication number: ZA897660B
Authority: ZA; South Africa
Prior art keywords: biologically active; active compounds; compounds; 6acyl; 4alkoxy
Prior art date: 1988-10-10

Application number

ZA897660A

Other languages

English (en)

Inventor

David Gwyn Cooper

Gwyn Cooper David

Andrew Derrick Gribble

Derrick Gribble Andrew

Original Assignee

Smith Kline French Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-10

Filing date

1989-10-09

Publication date

1990-09-26

1989-10-09 Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab

1990-09-26 Publication of ZA897660B publication Critical patent/ZA897660B/xx

Links

150000001875 compounds Chemical class 0.000 title abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000002015 acyclic group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ZA897660A 1988-10-10 1989-10-09 Biologically active compounds ZA897660B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888823731A GB8823731D0 (en)	1988-10-10	1988-10-10	Biologically active compounds

Publications (1)

Publication Number	Publication Date
ZA897660B true ZA897660B (en)	1990-09-26

Family

ID=10644962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA897660A ZA897660B (en)	1988-10-10	1989-10-09	Biologically active compounds

Country Status (11)

Country	Link
EP (1)	EP0365183B1 (de)
JP (1)	JPH02157258A (de)
AT (1)	ATE85608T1 (de)
AU (1)	AU621667B2 (de)
DE (1)	DE68904863T2 (de)
DK (1)	DK496089A (de)
ES (1)	ES2054020T3 (de)
GB (1)	GB8823731D0 (de)
IE (1)	IE893246L (de)
PT (1)	PT91931B (de)
ZA (1)	ZA897660B (de)

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US6099856A (en)	1992-06-15	2000-08-08	Emisphere Technologies, Inc.	Active agent transport systems
US6331318B1 (en)	1994-09-30	2001-12-18	Emisphere Technologies Inc.	Carbon-substituted diketopiperazine delivery systems
US6221367B1 (en)	1992-06-15	2001-04-24	Emisphere Technologies, Inc.	Active agent transport systems
US5693338A (en)	1994-09-29	1997-12-02	Emisphere Technologies, Inc.	Diketopiperazine-based delivery systems
US5451410A (en) *	1993-04-22	1995-09-19	Emisphere Technologies, Inc.	Modified amino acids for encapsulating active agents
US5578323A (en)	1992-06-15	1996-11-26	Emisphere Technologies, Inc.	Proteinoid carriers and methods for preparation and use thereof
US5443841A (en)	1992-06-15	1995-08-22	Emisphere Technologies, Inc.	Proteinoid microspheres and methods for preparation and use thereof
US5447728A (en) *	1992-06-15	1995-09-05	Emisphere Technologies, Inc.	Desferrioxamine oral delivery system
US5714167A (en)	1992-06-15	1998-02-03	Emisphere Technologies, Inc.	Active agent transport systems
US5629020A (en)	1994-04-22	1997-05-13	Emisphere Technologies, Inc.	Modified amino acids for drug delivery
US5541155A (en)	1994-04-22	1996-07-30	Emisphere Technologies, Inc.	Acids and acid salts and their use in delivery systems
US5792451A (en)	1994-03-02	1998-08-11	Emisphere Technologies, Inc.	Oral drug delivery compositions and methods
US5811127A (en)	1992-06-15	1998-09-22	Emisphere Technologies, Inc.	Desferrioxamine oral delivery system
US5401516A (en)	1992-12-21	1995-03-28	Emisphere Technologies, Inc.	Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5958457A (en)	1993-04-22	1999-09-28	Emisphere Technologies, Inc.	Compositions for the delivery of antigens
US5643957A (en)	1993-04-22	1997-07-01	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
ATE298561T1 (de)	1993-04-22	2005-07-15	Emisphere Tech Inc	Orale dareichungsform
US6610329B2 (en)	1993-04-22	2003-08-26	Emisphere Technologies Inc.	Compositions for the delivery of antigens
US5709861A (en)	1993-04-22	1998-01-20	Emisphere Technologies, Inc.	Compositions for the delivery of antigens
US6001347A (en)	1995-03-31	1999-12-14	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5866536A (en)	1995-03-31	1999-02-02	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5650386A (en)	1995-03-31	1997-07-22	Emisphere Technologies, Inc.	Compositions for oral delivery of active agents
BR9604880A (pt)	1995-03-31	1998-05-19	Emisphere Tech Inc	Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5989539A (en)	1995-03-31	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6090958A (en)	1995-03-31	2000-07-18	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5965121A (en)	1995-03-31	1999-10-12	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5820881A (en)	1995-04-28	1998-10-13	Emisphere Technologies, Inc.	Microspheres of diamide-dicarboxylic acids
US5667806A (en)	1995-06-07	1997-09-16	Emisphere Technologies, Inc.	Spray drying method and apparatus
US5824345A (en)	1995-06-07	1998-10-20	Emisphere Technologies, Inc.	Fragrances and flavorants
US5750147A (en)	1995-06-07	1998-05-12	Emisphere Technologies, Inc.	Method of solubilizing and encapsulating itraconazole
US6051258A (en)	1995-06-07	2000-04-18	Emisphere Technologies, Inc.	Proteinoid emulsions and methods for preparation and use thereof
WO1997010197A1 (en)	1995-09-11	1997-03-20	Emisphere Technologies, Inc.	METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
IL126318A (en)	1996-03-29	2004-09-27	Emisphere Tech Inc	Compounds and compositions for delivering active agents and some novel carrier compounds
WO1997047288A1 (en)	1996-06-14	1997-12-18	Emisphere Technologies, Inc.	Microencapsulated fragrances and method for preparation
US5990166A (en)	1997-02-07	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6313088B1 (en)	1997-02-07	2001-11-06	Emisphere Technologies, Inc.	8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6358504B1 (en)	1997-02-07	2002-03-19	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5939381A (en)	1997-02-07	1999-08-17	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6060513A (en)	1997-02-07	2000-05-09	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5876710A (en)	1997-02-07	1999-03-02	Emisphere Technologies Inc.	Compounds and compositions for delivering active agents
US5879681A (en)	1997-02-07	1999-03-09	Emisphere Technolgies Inc.	Compounds and compositions for delivering active agents
US5804688A (en)	1997-02-07	1998-09-08	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5863944A (en)	1997-04-30	1999-01-26	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5962710A (en)	1997-05-09	1999-10-05	Emisphere Technologies, Inc.	Method of preparing salicyloylamino acids
BE1012386A3 (fr) *	1999-01-15	2000-10-03	Univ Liege	Derives de sulfonamides benzeniques et leurs utilisations.
IL145546A0 (en)	1999-04-05	2002-06-30	Emisphere Tech Inc	Disodium salts, monohydrates, and ethanol solvates for delivering active agents
US7279597B1 (en)	1999-11-05	2007-10-09	Emisphere Technologies, Inc.	Phenyl amine carboxylic acid compounds and compositions for delivering active agents
US7129274B1 (en)	1999-11-05	2006-10-31	Emisphere Technologies Inc.	Phenoxy carboxylic acid compounds and compositions for delivering active agents
ATE387430T1 (de)	1999-12-16	2008-03-15	Emisphere Tech Inc	Verbindungen und zusammensetzungen zur abgabe aktiver wirkstoffe

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3629320A (en) *	1969-04-09	1971-12-21	Geigy Chem Corp	2-(4-halo- and 4-trifluoromethylphenylsulfonamido)phenylacetic acids and esters thereof
DE3000377A1 (de) *	1980-01-07	1981-07-09	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds

1988
- 1988-10-10 GB GB888823731A patent/GB8823731D0/en active Pending
1989
- 1989-10-03 JP JP1258653A patent/JPH02157258A/ja active Pending
- 1989-10-05 AU AU42578/89A patent/AU621667B2/en not_active Ceased
- 1989-10-06 EP EP89310242A patent/EP0365183B1/de not_active Expired - Lifetime
- 1989-10-06 DE DE8989310242T patent/DE68904863T2/de not_active Expired - Fee Related
- 1989-10-06 ES ES89310242T patent/ES2054020T3/es not_active Expired - Lifetime
- 1989-10-06 AT AT89310242T patent/ATE85608T1/de not_active IP Right Cessation
- 1989-10-06 DK DK496089A patent/DK496089A/da not_active Application Discontinuation
- 1989-10-09 IE IE893246A patent/IE893246L/xx unknown
- 1989-10-09 PT PT91931A patent/PT91931B/pt not_active IP Right Cessation
- 1989-10-09 ZA ZA897660A patent/ZA897660B/xx unknown

Also Published As

Publication number	Publication date
DE68904863T2 (de)	1993-06-24
GB8823731D0 (en)	1988-11-16
DK496089A (da)	1990-04-11
AU621667B2 (en)	1992-03-19
IE893246L (en)	1990-04-10
EP0365183A1 (de)	1990-04-25
ES2054020T3 (es)	1994-08-01
DE68904863D1 (de)	1993-03-25
JPH02157258A (ja)	1990-06-18
AU4257889A (en)	1990-04-12
ATE85608T1 (de)	1993-02-15
PT91931A (pt)	1990-04-30
DK496089D0 (da)	1989-10-06
EP0365183B1 (de)	1993-02-10
PT91931B (pt)	1995-05-31

Publication	Publication Date	Title
ZA897660B (en)	1990-09-26	Biologically active compounds
DK602589A (da)	1990-05-31	Quinazolinonderivater
KR900700465A (ko)	1990-08-13	화합물
DE68914292D1 (de)	1994-05-11	Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
GB8804443D0 (en)	1988-03-23	Compounds
ZA89389B (en)	1989-10-25	Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia
ES552782A0 (es)	1987-11-01	Un procedimiento para preparar un compuesto de n-fenil-trans-4-guanidincometilciclohexanocarboxamida.
WO1989001330A3 (en)	1989-05-05	W-arylsulphonamidoalkanoic acids for treatment of thromboxane mediated diseases
KR880007070A (ko)	1988-08-26	백내장 치료용 약학 조성물
ATE88176T1 (de)	1993-04-15	2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
PT87310A (pt)	1988-05-01	Process for the preparation of thiadiazole guanidines
HUT47900A (en)	1989-04-28	Process for producing new amides of butenic acid and pharmaceutical compositions containing them as active components
ZA885358B (en)	1989-03-29	Uricosuric composition
FR2633292B1 (fr)	1990-11-09	Nouveaux derives de la 20,21-dinoreburnamenine substitues en 15 par un groupement amine, leur procede de preparation et les intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les reenfermant