ZA89894B - Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them - Google Patents

Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA89894B
ZA89894B ZA89894A ZA89894A ZA89894B ZA 89894 B ZA89894 B ZA 89894B ZA 89894 A ZA89894 A ZA 89894A ZA 89894 A ZA89894 A ZA 89894A ZA 89894 B ZA89894 B ZA 89894B
Authority
ZA
South Africa
Prior art keywords
perhydrocycloalka
imadazone
diones
preparation
pharmaceutical compositions
Prior art date
Application number
ZA89894A
Other languages
English (en)
Inventor
Mario Pinza
Pinza Mario
Carlo Farina
Farina Carlo
Alberto Cerri
Cerri Alberto
Maria Teresa Riccaboni
Teresa Riccaboni Maria
Original Assignee
Isf Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isf Spa filed Critical Isf Spa
Publication of ZA89894B publication Critical patent/ZA89894B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
ZA89894A 1988-02-08 1989-02-06 Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them ZA89894B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8819336A IT1233860B (it) 1988-02-08 1988-02-08 Derivati del peridroazacicloalca (1,2-a) imidazolo ad attivita' nootropa

Publications (1)

Publication Number Publication Date
ZA89894B true ZA89894B (en) 1991-10-30

Family

ID=11156852

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA89894A ZA89894B (en) 1988-02-08 1989-02-06 Perhydrocycloalka(1,2-a)imadazone-2,5-diones,process for their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (2) US5053422A (de)
EP (1) EP0335483A3 (de)
JP (1) JPH01246281A (de)
KR (1) KR890013013A (de)
CN (1) CN1036204A (de)
AU (2) AU616240B2 (de)
BR (1) BR8900541A (de)
CA (1) CA1324378C (de)
DD (2) DD291996A5 (de)
DK (1) DK55089A (de)
FI (1) FI890438L (de)
HU (2) HU204794B (de)
IT (1) IT1233860B (de)
NO (1) NO168424C (de)
NZ (1) NZ227833A (de)
PL (1) PL158198B1 (de)
PT (1) PT89657B (de)
RO (4) RO105965B1 (de)
RU (1) RU1799383C (de)
ZA (1) ZA89894B (de)
ZW (1) ZW1489A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9123641D0 (en) * 1991-11-07 1992-01-02 Isf Spa Process
TW304167B (de) * 1995-01-30 1997-05-01 Lilly Co Eli
PE17897A1 (es) * 1995-02-17 1997-06-12 Lilly Co Eli Formulacion transdermica en parche del 3-(4-butiltio)-1,2,5-tiadiazol-3-il)-1-azabiciclo (2,2,2) octano
ZA964008B (en) * 1995-06-02 1997-07-11 Akzo Nobel Nv Imidazo[1,5a]pyridine derived serine protease inhibitors
JP3905409B2 (ja) 2002-04-10 2007-04-18 タレックス光学工業株式会社 光学レンズ成型用ポリウレタン樹脂組成物および耐衝撃性合成樹脂レンズ
ITMI20030573A1 (it) * 2003-03-24 2004-09-25 Nikem Research Srl Composti ad azione nootropica, loro preparazione,
ITMI20070770A1 (it) 2007-04-16 2008-10-17 Brane Discovery S R L Impiego di dimiracetam nel trattamento del dolore cronico
US9593209B2 (en) 2009-10-22 2017-03-14 Dow Corning Corporation Process for preparing clustered functional polyorganosiloxanes, and methods for their use
PT2598504E (pt) * 2010-07-26 2014-07-14 Neurotune Ag Novo processo de fabrico de dimiracetam
JP6408491B2 (ja) 2013-02-11 2018-10-17 ダウ シリコーンズ コーポレーション 熱伝導性熱ラジカル硬化性シリコーン組成物を形成するためのｉｎｓｉｔｕ法
CN105189685B (zh) 2013-02-11 2017-08-08 道康宁公司 用于形成导热热自由基固化有机硅组合物的方法
KR102244164B1 (ko) 2013-02-11 2021-04-26 다우 실리콘즈 코포레이션 알콕시-작용성 실록산 반응성 수지를 포함하는 수분-경화성 핫멜트 실리콘 접착제 조성물
CN104968748B (zh) 2013-02-11 2017-03-29 道康宁公司 烷氧基官能化有机聚硅氧烷树脂和聚合物及其相关形成方法
CN104968751B (zh) 2013-02-11 2017-04-19 道康宁公司 包含簇合官能化聚有机硅氧烷和有机硅反应性稀释剂的可固化有机硅组合物
CN104968750B (zh) 2013-02-11 2017-04-19 道康宁公司 簇合官能化聚有机硅氧烷、形成所述簇合官能化聚有机硅氧烷的工艺及其使用方法
US9670392B2 (en) 2013-02-11 2017-06-06 Dow Corning Corporation Stable thermal radical curable silicone adhesive compositions
EP3196229B1 (de) 2015-11-05 2018-09-26 Dow Silicones Corporation Verzweigte polyorganosiloxane und zugehörige härtbare zusammensetzungen, verfahren, verwendungen und vorrichtungen
JOP20190251A1 (ar) 2017-05-31 2019-10-21 Metys Pharmaceuticals AG تركيبات تآزرية تشتمل على (r)-ديميراسيتام (1) و(s)-ديميراسيتام (2) بنسبة غير راسيمية

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334099A (en) * 1965-03-31 1967-08-01 Sandoz Ag Novel pyrrolo-diazepines, pyrrolo-imidazolidines, and pyrrolo-pyrimidines
FR2358891A1 (fr) * 1976-07-22 1978-02-17 Yamanouchi Pharma Co Ltd Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires
US4372966A (en) * 1980-09-15 1983-02-08 Warner-Lambert Company Use of dihydro-1H-pyrrolizine-3,5(2H,6H)-dione as a cognition activator
US4582838A (en) * 1984-08-24 1986-04-15 Warner-Lambert Company Derivatives of dihydro-1H-pyrrolo[1,2-c]imidazol-3,5-dione as cognition activators
US4677098A (en) * 1985-11-22 1987-06-30 Warner-Lambert Company Substituted dihydro-1H-pyrolizine-3,5(2H,6H)-diones

Also Published As

Publication number Publication date
PT89657B (pt) 1994-02-28
NZ227833A (en) 1991-09-25
FI890438A7 (fi) 1989-08-09
BR8900541A (pt) 1989-10-03
NO168424B (no) 1991-11-11
RO104070B1 (en) 1993-07-20
RO105965B1 (ro) 1993-01-30
PT89657A (pt) 1989-10-04
HU204794B (en) 1992-02-28
NO890515D0 (no) 1989-02-07
RU1799383C (ru) 1993-02-28
CN1036204A (zh) 1989-10-11
FI890438L (fi) 1989-08-09
HUT53363A (en) 1990-10-28
ZW1489A1 (en) 1989-08-02
EP0335483A3 (de) 1991-12-18
RO105964B1 (ro) 1993-01-30
IT1233860B (it) 1992-04-21
AU2969289A (en) 1989-08-10
KR890013013A (ko) 1989-09-20
EP0335483A2 (de) 1989-10-04
AU7947991A (en) 1991-09-12
HU904864D0 (en) 1991-01-28
JPH01246281A (ja) 1989-10-02
NO168424C (no) 1992-02-19
HU203104B (en) 1991-05-28
CA1324378C (en) 1993-11-16
DD283393A5 (de) 1990-10-10
US5130319A (en) 1992-07-14
NO890515L (no) 1989-08-09
RO105963B1 (ro) 1993-01-30
DK55089A (da) 1989-08-09
PL158198B1 (pl) 1992-08-31
DK55089D0 (da) 1989-02-07
AU616240B2 (en) 1991-10-24
DD291996A5 (de) 1991-07-18
FI890438A0 (fi) 1989-01-30
IT8819336A0 (it) 1988-02-08
US5053422A (en) 1991-10-01

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