ZA902909B - A method of preparing a freeze-dried formulation containing a drug - Google Patents

A method of preparing a freeze-dried formulation containing a drug

Info

Publication number
ZA902909B
ZA902909B ZA902909A ZA902909A ZA902909B ZA 902909 B ZA902909 B ZA 902909B ZA 902909 A ZA902909 A ZA 902909A ZA 902909 A ZA902909 A ZA 902909A ZA 902909 B ZA902909 B ZA 902909B
Authority
ZA
South Africa
Prior art keywords
freeze
frozen
liquid
drug
preparing
Prior art date
Application number
ZA902909A
Other languages
English (en)
Inventor
Seigo Ueda
Ueda Seigo
Takashi Shiokari
Shiokari Takashi
Kunio Hashi
Hashi Kunio
Akira Kusai
Kusai Akira
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of ZA902909B publication Critical patent/ZA902909B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
    • A23B2/00Preservation of foods or foodstuffs, in general
    • A23B2/90Preservation of foods or foodstuffs, in general by drying or kilning; Subsequent reconstitution
    • A23B2/92Freeze drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Medicines Containing Plant Substances (AREA)
ZA902909A 1989-04-18 1990-04-18 A method of preparing a freeze-dried formulation containing a drug ZA902909B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9856189 1989-04-18

Publications (1)

Publication Number Publication Date
ZA902909B true ZA902909B (en) 1991-12-24

Family

ID=14223093

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902909A ZA902909B (en) 1989-04-18 1990-04-18 A method of preparing a freeze-dried formulation containing a drug

Country Status (16)

Country Link
US (1) US5044091B1 (ja)
EP (1) EP0394050B1 (ja)
JP (1) JPH07116022B2 (ja)
KR (1) KR950007908B1 (ja)
AT (1) ATE210427T1 (ja)
AU (1) AU624494B2 (ja)
CA (1) CA2014714C (ja)
DE (1) DE69033874T2 (ja)
DK (1) DK0394050T3 (ja)
ES (1) ES2165839T3 (ja)
FI (1) FI104360B (ja)
HU (1) HU204993B (ja)
NO (1) NO180801C (ja)
NZ (1) NZ233344A (ja)
PH (1) PH27522A (ja)
ZA (1) ZA902909B (ja)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215756A (en) * 1989-12-22 1993-06-01 Gole Dilip J Preparation of pharmaceutical and other matrix systems by solid-state dissolution
US5169834A (en) * 1990-11-30 1992-12-08 American Cyanamid Company Compositions and method for reducing vial breakage during lyophilization
GR910100193A (el) * 1991-05-03 1993-03-31 Mediventures Inc Παρασκευη φαρμακευτικων και αλλων περιβληματων με διαλυση σε στερεα κατασταση.
US5362442A (en) 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
US20040067157A1 (en) * 1993-07-22 2004-04-08 Clearant, Inc. Methods for sterilizing biological materials
DE19547973C2 (de) * 1995-12-21 1999-08-12 Plantamed Arzneimittel Gmbh Verfahren zur schonenden Keimreduzierung von pharmazeutischen Zubereitungen
IL120202A (en) * 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
EP1049458B1 (en) * 1998-01-21 2003-03-26 Takeda Chemical Industries, Ltd. Lyophilization method for sustained-release preparations
US20040086420A1 (en) * 2000-03-23 2004-05-06 Macphee Martin J. Methods for sterilizing serum or plasma
US6682695B2 (en) * 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US7252799B2 (en) * 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US6783968B2 (en) 2001-09-24 2004-08-31 Clearant, Inc. Methods for sterilizing preparations of glycosidases
US20030095890A1 (en) * 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
US20110091353A1 (en) * 2001-09-24 2011-04-21 Wilson Burgess Methods for Sterilizing Tissue
US20030185702A1 (en) * 2002-02-01 2003-10-02 Wilson Burgess Methods for sterilizing tissue
US20030124023A1 (en) * 2001-12-21 2003-07-03 Wilson Burgess Method of sterilizing heart valves
US7387796B2 (en) * 2002-01-30 2008-06-17 Hebert Rolland F Stable compositions of S-adenosyl-l-methionine with dextran
US20030180181A1 (en) * 2002-02-01 2003-09-25 Teri Greib Methods for sterilizing tissue
US6908591B2 (en) * 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US20040013562A1 (en) * 2002-07-18 2004-01-22 Wilson Burgess Methods for sterilizing milk.
JP2006111532A (ja) * 2004-10-12 2006-04-27 Yoshindo:Kk パニペネム含有ダブルバッグ型製剤
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
TWI343262B (en) * 2006-09-26 2011-06-11 Schering Corp Rapidly disintegrating lyophilized oral formulations of a thrombin receptor antagonist
US10548839B2 (en) * 2010-03-16 2020-02-04 Wei Tian Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form
US9795745B2 (en) 2012-06-26 2017-10-24 Bioneer A/S Syringe with a hollow plunger
JP6968184B2 (ja) 2016-10-25 2021-11-17 キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド 速崩壊多層錠のための異なる密度の組成物
JP7575776B2 (ja) * 2020-12-09 2024-10-30 アスザックフーズ株式会社 乾燥食品製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB797774A (en) * 1955-03-02 1958-07-09 Armour & Co Improvements in and relating to the production and packaging of stratiform products
US3616543A (en) * 1969-10-31 1971-11-02 Merck & Co Inc Method of producing a multicomponent lyophilized product
FR2109201A6 (ja) * 1970-10-07 1972-05-26 Air Liquide
EP0069176A1 (en) * 1981-07-03 1983-01-12 American Home Products Corporation Method of obtaining a lyophilized product
US4433558A (en) * 1981-08-25 1984-02-28 Cheng Chen Yen Parallel contact distillative freezing process for separating volatile mixtures and apparatuses for use therein
EP0081913B1 (en) * 1981-12-11 1985-06-26 JOHN WYETH & BROTHER LIMITED Process and apparatus for freezing a liquid medium
US4430807A (en) * 1982-05-17 1984-02-14 The Dow Chemical Company Process for drying water-wet membranes
JPS6168412A (ja) * 1984-09-10 1986-04-08 Fujisawa Pharmaceut Co Ltd 医薬品の凍結乾燥方法
IL78930A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Lyophilized emulsion compositions for parenteral administration
FR2601702A1 (fr) * 1986-07-21 1988-01-22 Atochem Composition a base de chlorure de methylene - son utilisation pour le degraissage des metaux

Also Published As

Publication number Publication date
FI104360B (fi) 2000-01-14
NZ233344A (en) 1991-05-28
PH27522A (en) 1993-08-18
JPH0347115A (ja) 1991-02-28
DE69033874D1 (de) 2002-01-24
AU624494B2 (en) 1992-06-11
US5044091A (en) 1991-09-03
EP0394050A2 (en) 1990-10-24
HUT54885A (en) 1991-04-29
JPH07116022B2 (ja) 1995-12-13
HK1010685A1 (en) 1999-06-25
AU5328990A (en) 1990-10-25
ATE210427T1 (de) 2001-12-15
KR900015715A (ko) 1990-11-10
ES2165839T3 (es) 2002-04-01
EP0394050B1 (en) 2001-12-12
DE69033874T2 (de) 2002-08-29
EP0394050A3 (en) 1992-06-10
HU204993B (en) 1992-03-30
CA2014714A1 (en) 1990-10-18
KR950007908B1 (ko) 1995-07-21
NO180801B (no) 1997-03-24
HU902472D0 (en) 1990-08-28
FI901947A0 (fi) 1990-04-18
US5044091B1 (en) 1997-12-30
DK0394050T3 (da) 2002-02-11
CA2014714C (en) 2000-07-18
NO901691D0 (no) 1990-04-17
NO901691L (no) 1990-10-19
NO180801C (no) 1997-07-02

Similar Documents

Publication Publication Date Title
US5044091B1 (en) Method of preparing a freeze-dried formulation of a drug
NO862689D0 (no) Dehydratisert kapsel, samt fremgangsmaate for fremstilling av en slik.
HUT51617A (en) Process for producing oxadiazole derivatives and pharmaceutical preparations containing these compounds as active substance
HU906341D0 (en) Process for producing peptonic derivatives modified with sugar and pharmaceutical preparatives containing these compounds as active substance
NO871791D0 (no) Fremgangsmaate for fremstilling av farmasoeytiske preparater inneholdende syrelabile stoffer for oral anvendelse.
GB9320668D0 (en) Liposomes containing particulare materials
FI893504A0 (fi) Menetelmä terapeuttisesti käyttökelpoisen, mikro- ja/tai nanopartikkeleita sisältävän yhtenäisen, kiinteän ja huokoisen muodon valmistamiseksi
GB2198134B (en) Substituted a-amino acids, their preparation and pharmaceutical compositions containing them
NO179359C (no) Fremgangsmåte for fremstilling av farmasöytisk preparat inneholdende somatostatinanaloger.
ATE100095T1 (de) 2,2-dimethylchromenderivate, verfahren zur herstellung und diese enthaltende pharmazeutische zusammenstellungen.
ATE58538T1 (de) 4-chinolon-3-carbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
HUT44403A (en) Herbicides comprising 3-benzoyl-4-oxo-lactam derivatives as active substance and process for preparing the active substances
HUT44256A (en) Process for preparing in 1,8-position bridged 4-quinolone-3-carboxylic acid derivatives and pharmaceuticals comprising the same as active substance
FI873701L (fi) Menetelmä kylmäkuivattujen farmaseuttisten fenyylikinoliinikarboksyylihappokoostumusten valmistamiseksi
HUT43318A (en) Fungicides comprising 2-cyano-benzimidazole derivatives as active substance and process for preparing the active substances
HUT44018A (en) Insecticides and acaricides containing as active substance 5-amin-1-phenil-pirasole derivatives and process for production of the active substances
IT1228437B (it) "derivati di 2,3,4,5,6,7 esaidro 2,7-metano-1,5 benzossazonina (rispettivamente 1,4 benzossazonina), procedimento per la loro preparazione e prodotti medicinali che contengono questi composti.
DE3790355T (de) Verfahren zur herstellung magensalzsaeureneutralisierender pharmazeutischer praeparate mit grosser saeurebindender kapazitaet, verzoegerter wirkungsdauer und vergroesserter bioverfuegbarkeit
SE8406265D0 (sv) Beredning for farmaceutiskt eller veterinermedicinskt bruk
IT1237515B (it) Procedimento per la preparazione di primicina idrosolubile e suoi componenti e composizioni farmaceutiche che li contengono.
FI873548A0 (fi) Menetelmä oktreotidiä sisältävän farmaseuttisen koostumuksen valmistamiseksi
HUT44440A (en) Process for preparing pvp-i complex and stable pharmaceutical comprising the same as active substance
Unit et al. Accelerated stability studies of widely used pharmaceutical substances under simulated tropical conditions
HUT43235A (en) Insecticidal compositions comprising 2-(benzofuran-7-yl)-hydrazinecarboxylic acid ester derivatives as active substance and process for preparing the active substances
NO914378D0 (no) Fremgangsmaate for fremstilling av oppslemminger med hoeyt innhold av faste stoffer