ZA909445B - Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives - Google Patents

Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives

Info

Publication number: ZA909445B
Authority: ZA; South Africa
Prior art keywords: 6alkyl; aryl; compounds; dihydroimidazo; thiazole derivatives
Prior art date: 1989-11-24

Application number

ZA909445A

Other languages

English (en)

Inventor

Alfons Herman Marg Raeymaekers

Herman Margaretha Raeym Alfons

Leopold Frans Corneel Roevens

Frans Corneel Roevens Leopold

Willy Joannes Carolu Laerhoven

Joannes Carolus Van Laer Willy

Jean Pierre Frans Van Wauwe

Pierre Frans Van Wauwe Jean

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-24

Filing date

1990-11-23

Publication date

1992-07-29

1990-11-23 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1992-07-29 Publication of ZA909445B publication Critical patent/ZA909445B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

ZA909445A 1989-11-24 1990-11-23 Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives ZA909445B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US44084289A	1989-11-24	1989-11-24

Publications (1)

Publication Number	Publication Date
ZA909445B true ZA909445B (en)	1992-07-29

Family

ID=23750399

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA909445A ZA909445B (en)	1989-11-24	1990-11-23	Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives

Country Status (25)

Country	Link
EP (1)	EP0430334B1 (de)
JP (1)	JPH03170487A (de)
KR (1)	KR910009714A (de)
CN (1)	CN1032754C (de)
AT (1)	ATE127795T1 (de)
AU (1)	AU630766B2 (de)
BG (1)	BG60587B1 (de)
CA (1)	CA2028756A1 (de)
CZ (1)	CZ281422B6 (de)
DE (1)	DE69022370T2 (de)
FI (1)	FI93459C (de)
HU (1)	HU206361B (de)
IE (1)	IE67656B1 (de)
IL (1)	IL96435A (de)
MY (1)	MY131024A (de)
NO (1)	NO300065B1 (de)
NZ (1)	NZ236026A (de)
PL (1)	PL165413B1 (de)
PT (1)	PT95978B (de)
RO (1)	RO108869B1 (de)
RU (1)	RU2051153C1 (de)
YU (1)	YU47955B (de)
ZA (1)	ZA909445B (de)
ZM (1)	ZM5390A1 (de)
ZW (1)	ZW17890A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0524055A1 (de) *	1991-07-19	1993-01-20	Synthelabo	Imidazo(2,1-b)benzothiazolderivate, Verfahren zu ihrer Herstellung und ihre therapeutische Verwendung
US6165253A (en) *	1994-05-23	2000-12-26	New Jersey Institute Of Technology	Apparatus for removal of volatile organic compounds from gaseous mixtures
RU2129870C1 (ru) *	1998-04-07	1999-05-10	Ливицкий Василий Иванович	Способ получения антимикробного и противоопухолевого лечебного средства
ATE380548T1 (de)	1999-01-29	2007-12-15	Univ Illinois	Verwendung von p53 inhibitoren zur behandlung von nebenerscheinungen bei der krebstherapie
EP1797880A3 (de) *	1999-01-29	2010-04-28	Board Of Trustees Of The University Of Illinois	Verwendung von P53-Hemmern zur Behandlung der Nebenwirkungen der Krebsbehandlung
AU2005288522B2 (en)	2004-09-28	2012-06-28	Quark Pharmaceuticals, Inc.	Oligoribonucleotides and methods of use thereof for treatment of alopecia, acute renal failure and other diseases
RU2282438C1 (ru) *	2005-03-24	2006-08-27	Александра Петровна Безрукова	Средство, обладающее противоопухолевой активностью
US7825099B2 (en)	2006-01-20	2010-11-02	Quark Pharmaceuticals, Inc.	Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
US7910566B2 (en)	2006-03-09	2011-03-22	Quark Pharmaceuticals Inc.	Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
HRP20140522T1 (hr)	2007-06-27	2014-08-15	Quark Pharmaceuticals, Inc.	Pripravci i metode za inhibiranje izražaja proapoptotiäśkih gena
CN104557979A (zh) *	2013-10-23	2015-04-29	丹阳恒安化学科技研究所有限公司	盐酸左旋咪唑的制备方法
RU2763739C1 (ru) *	2021-06-28	2021-12-30	Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ)	(Z)-9-ароил-8-гидрокси-6-(2-гидроксифенил)-2-(((Z)-2-оксоиндолин-3-илиден)гидразоно)-1-тиа-3,6-диазаспиро[4.4]нон-8-ен-4,7-дионы, обладающие противомикробной активностью
JP7814782B2 (ja) *	2021-11-29	2026-02-17	オーシャンユニバーシティオブチャイナ	イミダゾチアゾール誘導体およびその製造方法と使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU409983B2 (en) *	1965-07-19	1970-12-31	Imperial Chemical Industries Of Australia New Zealand Limited	Process for the manufacture of thia zolidines and thiazolidines produced thereby
GB1444743A (en) *	1973-09-20	1976-08-04	Pfizer Ltd	7-substituted imidazo-1,1-b-thiazolium and 9-substituted thiazolo-3,2-a-benzimidazolium derivatives having hypogly caemic and/or growth promotant properties
US4340738A (en) *	1979-06-21	1982-07-20	Janssen Pharmaceutica, N.V.	2,3-Dihydro-imidazo[2,1-b]benzothiazoles

1990
- 1990-10-29 CA CA002028756A patent/CA2028756A1/en not_active Abandoned
- 1990-11-09 NZ NZ236026A patent/NZ236026A/xx unknown
- 1990-11-15 DE DE69022370T patent/DE69022370T2/de not_active Expired - Fee Related
- 1990-11-15 AT AT90203031T patent/ATE127795T1/de active
- 1990-11-15 EP EP90203031A patent/EP0430334B1/de not_active Expired - Lifetime
- 1990-11-17 JP JP2310193A patent/JPH03170487A/ja active Pending
- 1990-11-20 YU YU220890A patent/YU47955B/sh unknown
- 1990-11-21 MY MYPI90002052A patent/MY131024A/en unknown
- 1990-11-21 AU AU66809/90A patent/AU630766B2/en not_active Ceased
- 1990-11-22 BG BG93298A patent/BG60587B1/bg unknown
- 1990-11-22 IL IL9643590A patent/IL96435A/en not_active IP Right Cessation
- 1990-11-22 CZ CS905803A patent/CZ281422B6/cs unknown
- 1990-11-23 PT PT95978A patent/PT95978B/pt not_active IP Right Cessation
- 1990-11-23 KR KR1019900019029A patent/KR910009714A/ko not_active Ceased
- 1990-11-23 PL PL90287907A patent/PL165413B1/pl unknown
- 1990-11-23 ZA ZA909445A patent/ZA909445B/xx unknown
- 1990-11-23 IE IE424190A patent/IE67656B1/en not_active IP Right Cessation
- 1990-11-23 RO RO146390A patent/RO108869B1/ro unknown
- 1990-11-23 ZW ZW178/90A patent/ZW17890A1/xx unknown
- 1990-11-23 ZM ZM53/90A patent/ZM5390A1/xx unknown
- 1990-11-23 NO NO905086A patent/NO300065B1/no unknown
- 1990-11-23 RU SU904831684A patent/RU2051153C1/ru active
- 1990-11-23 FI FI905788A patent/FI93459C/fi not_active IP Right Cessation
- 1990-11-23 HU HU907633A patent/HU206361B/hu not_active IP Right Cessation
- 1990-11-24 CN CN90109407A patent/CN1032754C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
HUT59414A (en)	1992-05-28
FI93459B (fi)	1994-12-30
HU206361B (en)	1992-10-28
RU2051153C1 (ru)	1995-12-27
ATE127795T1 (de)	1995-09-15
BG60587B1 (bg)	1995-09-29
PL287907A1 (en)	1992-04-21
DE69022370D1 (de)	1995-10-19
CN1052117A (zh)	1991-06-12
ZM5390A1 (en)	1992-06-30
HU907633D0 (en)	1991-06-28
IE904241A1 (en)	1991-06-05
CZ281422B6 (cs)	1996-09-11
YU47955B (sh)	1996-07-24
EP0430334A1 (de)	1991-06-05
AU630766B2 (en)	1992-11-05
NO300065B1 (no)	1997-04-01
IL96435A0 (en)	1991-08-16
PT95978B (pt)	1998-01-30
EP0430334B1 (de)	1995-09-13
CZ580390A3 (en)	1996-06-12
RO108869B1 (ro)	1994-09-30
FI905788L (fi)	1991-05-25
JPH03170487A (ja)	1991-07-24
CA2028756A1 (en)	1991-05-25
BG93298A (bg)	1993-12-24
AU6680990A (en)	1991-05-30
PL165413B1 (pl)	1994-12-30
NO905086D0 (no)	1990-11-23
YU220890A (sh)	1992-12-21
KR910009714A (ko)	1991-06-28
FI905788A0 (fi)	1990-11-23
FI93459C (fi)	1995-04-10
DE69022370T2 (de)	1996-03-14
PT95978A (pt)	1991-09-13
NO905086L (no)	1991-05-27
IL96435A (en)	1995-03-15
MY131024A (en)	2007-07-31
CN1032754C (zh)	1996-09-11
NZ236026A (en)	1992-03-26
ZW17890A1 (en)	1992-07-08
IE67656B1 (en)	1996-04-17

Publication	Publication Date	Title
ZA895613B (en)	1990-05-30	Chemical compounds
PT89047A (pt)	1988-12-01	Processo para a preparacao de derivados de piridazinamina
AU630766B2 (en)	1992-11-05	Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b) thiazole derivatives
HU9202047D0 (en)	1992-09-28	Method for producing n-phenyl-thiourea derivatives and pharmaceutical prepartives containing these compounds as active agents
PT90034A (pt)	1989-11-10	Processo para a preparacao de tetra-hidroimidazo-{1,4}benzodiazepina-2-onas
ZA903663B (en)	1992-01-29	Antirhinoviral(thio)morpholinyl and piperazinyl alkylphenol ethers
AU5494290A (en)	1990-11-15	Antirhinoviral pyridazinamines
PT91613A (pt)	1990-03-30	Process for the preparation of antihypertensive 3-piperidinyl-indazole derivatives
GB8801300D0 (en)	1988-02-17	New compositions of matter
DE3362523D1 (en)	1986-04-17	Optically active imidazolylpropanol compounds, and their production and use