ZA917695B - Fibrinogen receptor antagonists - Google Patents

Fibrinogen receptor antagonists

Info

Publication number: ZA917695B
Authority: ZA; South Africa
Prior art keywords: receptor antagonists; fibrinogen receptor; fibrinogen; antagonists; receptor
Prior art date: 1990-09-27

Application number

ZA917695A

Other languages

English (en)

Inventor

Mark E Duggan

E Duggan Mark

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-27

Filing date

1991-09-26

Publication date

1992-05-27

1991-09-26 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1992-05-27 Publication of ZA917695B publication Critical patent/ZA917695B/xx

Links

239000002319 fibrinogen receptor antagonist Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA917695A 1990-09-27 1991-09-26 Fibrinogen receptor antagonists ZA917695B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US58928290A	1990-09-27	1990-09-27

Publications (1)

Publication Number	Publication Date
ZA917695B true ZA917695B (en)	1992-05-27

Family

ID=24357362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA917695A ZA917695B (en)	1990-09-27	1991-09-26	Fibrinogen receptor antagonists

Country Status (15)

Country	Link
EP (1)	EP0479481A3 (cs)
JP (1)	JPH0517498A (cs)
KR (1)	KR920006373A (cs)
CN (1)	CN1060293A (cs)
AU (1)	AU8477891A (cs)
CA (1)	CA2052057A1 (cs)
CS (1)	CS294791A3 (cs)
FI (1)	FI914532A7 (cs)
HU (1)	HUT60751A (cs)
IE (1)	IE913380A1 (cs)
IL (1)	IL99539A0 (cs)
MX (1)	MX9101311A (cs)
NO (1)	NO913786L (cs)
PT (1)	PT99095A (cs)
ZA (1)	ZA917695B (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5939412A (en) *	1992-06-26	1999-08-17	Smithkline Beecham Corporation	Bicyclic fibrinogen antagonists
AU666318B2 (en) *	1991-06-28	1996-02-08	Smithkline Beecham Corporation	Bicyclic fibrinogen antagonists
US5340798A (en) *	1992-10-14	1994-08-23	Merck & Co., Inc.	Fibrinogen receptor antagonists
JP3322878B2 (ja) *	1992-10-14	2002-09-09	メルクエンドカンパニーインコーポレーテッド	フィブリノーゲンレセプターアンタゴニスト
US5358956A (en) *	1992-10-14	1994-10-25	Merck & Co., Inc.	Fibrinogen receptor antagonists
WO1994008962A1 (en) *	1992-10-14	1994-04-28	Merck & Co., Inc.	Fibrinogen receptor antagonists
WO1994012181A1 (en) *	1992-12-01	1994-06-09	Merck & Co., Inc.	Fibrinogen receptor antagonists
WO1994022834A1 (en) *	1993-03-29	1994-10-13	Zeneca Limited	Heterocyclic derivatives as platelet aggregation inhibitors
US5652242A (en) *	1993-03-29	1997-07-29	Zeneca Limited	Heterocyclic derivatives
GB9406144D0 (en) *	1993-03-29	1994-05-18	Zeneca Ltd	Heterocyclic compounds
US5750754A (en) *	1993-03-29	1998-05-12	Zeneca Limited	Heterocyclic compounds
US5753659A (en) *	1993-03-29	1998-05-19	Zeneca Limited	Heterocyclic compouds
US5334596A (en) *	1993-05-11	1994-08-02	Merck & Co., Inc.	Fibrinogen receptor antagonists
US5463011A (en) *	1993-06-28	1995-10-31	Zeneca Limited	Acid derivatives
GB9313268D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Chemical compounds
GB9313285D0 (en) *	1993-06-28	1993-08-11	Zeneca Ltd	Acid derivatives
US5397791A (en) *	1993-08-09	1995-03-14	Merck & Co., Inc.	Fibrinogen receptor antagonists
SK47796A3 (en) *	1993-10-15	1997-03-05	Rhone Poulenc Rorer Pharma	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
US5780590A (en) *	1993-10-15	1998-07-14	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
US6274705B1 (en)	1996-05-02	2001-08-14	Aventis Pharmaceuticals Products Inc.	Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
MA23420A1 (fr) *	1994-01-07	1995-10-01	Smithkline Beecham Corp	Antagonistes bicycliques de fibrinogene.
US6458784B1 (en)	1994-06-29	2002-10-01	Smithkline Beecham Corporation	Vitronectin receptor antagonists
US5451578A (en) *	1994-08-12	1995-09-19	Merck & Co., Inc.	Fibrinogen receptor antagonists
US5525617A (en) *	1994-08-24	1996-06-11	Merck & Co., Inc.	Fibrinogen receptor antagonists
US5977101A (en) *	1995-06-29	1999-11-02	Smithkline Beecham Corporation	Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity
US5789421A (en) *	1995-10-26	1998-08-04	Merck & Co., Inc.	Fibrinogen receptor antagonist
US5780480A (en) *	1996-02-28	1998-07-14	Merck & Co., Inc.	Fibrinogen receptor antagonists
AU754936B2 (en) *	1996-11-27	2002-11-28	Aventis Pharmaceuticals Inc.	Pharmaceutical composition comprising a compound having anti-Xa activity and a platelet aggregation antagonist compound
EP1747219A4 (en) *	2004-05-13	2010-05-26	Glaxo Group Ltd	Antagonists of muscarinic acetylcholine receptor

1991
- 1991-09-20 IL IL99539A patent/IL99539A0/xx unknown
- 1991-09-23 CA CA002052057A patent/CA2052057A1/en not_active Abandoned
- 1991-09-25 EP EP19910308722 patent/EP0479481A3/en not_active Withdrawn
- 1991-09-26 KR KR1019910016759A patent/KR920006373A/ko not_active Withdrawn
- 1991-09-26 CS CS912947A patent/CS294791A3/cs unknown
- 1991-09-26 ZA ZA917695A patent/ZA917695B/xx unknown
- 1991-09-26 PT PT99095A patent/PT99095A/pt not_active Application Discontinuation
- 1991-09-26 NO NO91913786A patent/NO913786L/no unknown
- 1991-09-26 AU AU84778/91A patent/AU8477891A/en not_active Abandoned
- 1991-09-26 FI FI914532A patent/FI914532A7/fi not_active Application Discontinuation
- 1991-09-26 HU HU913074A patent/HUT60751A/hu unknown
- 1991-09-26 CN CN91109394A patent/CN1060293A/zh active Pending
- 1991-09-26 IE IE338091A patent/IE913380A1/en unknown
- 1991-09-27 MX MX9101311A patent/MX9101311A/es unknown
- 1991-09-27 JP JP3248809A patent/JPH0517498A/ja active Pending

Also Published As

Publication number	Publication date
CA2052057A1 (en)	1992-03-28
JPH0517498A (ja)	1993-01-26
HU913074D0 (en)	1992-01-28
MX9101311A (es)	1992-05-04
CN1060293A (zh)	1992-04-15
EP0479481A2 (en)	1992-04-08
AU8477891A (en)	1992-04-02
IE913380A1 (en)	1992-04-08
EP0479481A3 (en)	1993-07-28
HUT60751A (en)	1992-10-28
FI914532A0 (fi)	1991-09-26
IL99539A0 (en)	1992-08-18
PT99095A (pt)	1992-08-31
NO913786D0 (no)	1991-09-26
CS294791A3 (en)	1992-04-15
NO913786L (no)	1992-03-30
FI914532A7 (fi)	1992-03-28
KR920006373A (ko)	1992-04-27

Publication	Publication Date	Title
EP0479481A3 (en)	1993-07-28	Fibrinogen receptor antagonists
GB9405317D0 (en)	1994-04-27	Fibrinogen receptor antagonists
FI914533A7 (fi)	1992-03-28	Fibrinogeenireseptoriantagonisteja
FI914535A7 (fi)	1992-03-28	Uusia fibrinogeenireseptoriantagonisteja
DE69207351D1 (de)	1996-02-15	Fibrinogen-Rezeptor-Antagoniste
FI934894A7 (fi)	1993-11-05	Fibrinogeenireseptorin antagonisteja
EP0475206A3 (en)	1992-08-05	Angiotensin ii receptor antagonists
AU3665793A (en)	1993-09-13	Fibrinogen receptor antagonists
FI905022A7 (fi)	1991-04-14	Fibrinogeenin reseptorin antagonisteja
GB9020051D0 (en)	1990-10-24	Muscarinic receptor antagonists
EP0912175A4 (en)	1999-09-08	FIBRINOGENIC RECEPTOR ANTAGONISTS
FI905023A7 (fi)	1991-04-14	Fibrinogeenin reseptorin antagonisteja
EP0796098A4 (en)	1998-04-29	FIBRINOGEN RECEPTOR ANTAGONISTS
EP0885213A4 (en)	1999-04-28	FIBRINOGEN RECEPTOR ANTAGONISTS
HU9502028D0 (en)	1995-09-28	Fibrinogen receptor antagonists
EP0801650A4 (en)	1998-05-06	FIBRINOGEN RECEPTOR ANTAGONISTS
GR3024965T3 (en)	1998-01-30	Process for preparing fibrinogen receptor antagonists
AU5322994A (en)	1994-05-09	Fibrinogen receptor antagonists
GB9320799D0 (en)	1993-12-01	Fibrinogen receptor antagonists
EP0794779A4 (en)	1998-04-29	FIBRINOGENIC RECEPTOR ANTAGONISTS
GB9515852D0 (en)	1995-10-04	Fibrinogen receptor antagonists
ZA894097B (en)	1990-06-27	Alpha-adrenergic receptor antagonists
EP0800395A4 (en)	1998-04-29	FIBRINOGENIC RECEPTOR ANTAGONISTS
ZA917693B (en)	1992-05-27	Fibrinogen receptor antagonists
GB9516643D0 (en)	1995-10-18	Fibrinogen receptor antagonists