ZA9193B - Purification of human interleukin-4 from a secreted escherichia coli mutant - Google Patents

Purification of human interleukin-4 from a secreted escherichia coli mutant

Info

Publication number: ZA9193B
Authority: ZA; South Africa
Prior art keywords: secreted; sodium chloride; coli mutant; purification; escherichia coli
Prior art date: 1990-05-31

Application number

ZA9193A

Other languages

English (en)

Inventor

John Chu-Tay Tang

Chu-Tay Tang John

David Naveh

Naveh David

T L Nagabhushan

L Nagabhushan T

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-05-31

Filing date

1991-01-04

Publication date

1991-09-25

1991-01-04 Application filed by Schering Corp filed Critical Schering Corp

1991-09-25 Publication of ZA9193B publication Critical patent/ZA9193B/xx

Links

101001002709 Homo sapiens Interleukin-4 Proteins 0.000 title abstract 3
102000055229 human IL4 Human genes 0.000 title abstract 3
241000588724 Escherichia coli Species 0.000 title abstract 2
238000000746 purification Methods 0.000 title 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 6
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
239000011780 sodium chloride Substances 0.000 abstract 3
239000000872 buffer Substances 0.000 abstract 2
239000000243 solution Substances 0.000 abstract 2
229920000936 Agarose Polymers 0.000 abstract 1
238000005277 cation exchange chromatography Methods 0.000 abstract 1
239000007979 citrate buffer Substances 0.000 abstract 1
238000011026 diafiltration Methods 0.000 abstract 1
230000007717 exclusion Effects 0.000 abstract 1
230000004151 fermentation Effects 0.000 abstract 1
238000000855 fermentation Methods 0.000 abstract 1
238000005227 gel permeation chromatography Methods 0.000 abstract 1
239000008363 phosphate buffer Substances 0.000 abstract 1
238000005406 washing Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5406—IL-4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ZA9193A 1990-05-31 1991-01-04 Purification of human interleukin-4 from a secreted escherichia coli mutant ZA9193B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/531,270 US5077388A (en)	1990-05-31	1990-05-31	Purification of human interleukin-4 from a secreted escherichia coli mutant

Publications (1)

Publication Number	Publication Date
ZA9193B true ZA9193B (en)	1991-09-25

Family

ID=24116964

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9193A ZA9193B (en)	1990-05-31	1991-01-04	Purification of human interleukin-4 from a secreted escherichia coli mutant

Country Status (16)

Country	Link
US (1)	US5077388A (de)
EP (1)	EP0537148B1 (de)
JP (1)	JP2573767B2 (de)
AT (1)	ATE136552T1 (de)
AU (1)	AU659993B2 (de)
CA (1)	CA2084186C (de)
DE (1)	DE69118696T2 (de)
DK (1)	DK0537148T3 (de)
ES (1)	ES2085986T3 (de)
GR (1)	GR3019705T3 (de)
IE (1)	IE73668B1 (de)
IL (1)	IL96880A0 (de)
MY (1)	MY130013A (de)
NZ (1)	NZ236699A (de)
WO (1)	WO1991018919A1 (de)
ZA (1)	ZA9193B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100191223B1 (ko) *	1989-07-28	1999-06-15	둘락 노먼 씨.	인터루킨-4의 정제방법 및 이를 함유하는 약제학적 조성물
US5840851A (en) *	1993-07-23	1998-11-24	Plomer; J. Jeffrey	Purification of hemoglobin
KR0141651B1 (ko) *	1994-09-07	1998-06-15	강재헌	금속이온 친화성 크로마토그라피를 이용한 히루딘의 정제방법
AU8671798A (en) *	1997-07-30	1999-02-22	Betagene, Inc.	Methods and compositions relating to no-mediated cytotoxicity
US6171856B1 (en)	1997-07-30	2001-01-09	Board Of Regents, The University Of Texas System	Methods and compositions relating to no-mediated cytotoxicity
EP3088412B1 (de)	2001-03-09	2021-05-05	Chugai Seiyaku Kabushiki Kaisha	Proteinaufreinigungsverfahren

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL80678A (en) *	1985-11-19	1999-05-09	Schering Biotech Corp	Human interleukin-4
EP0374791A1 (de) *	1988-12-21	1990-06-27	Schering Corporation	Verwendung von Interleukin-4 zur Herstellung eines Arzneimittels zur Herabsetzung der Cholesterolkoncentration des Blutes
KR100191223B1 (ko) *	1989-07-28	1999-06-15	둘락 노먼 씨.	인터루킨-4의 정제방법 및 이를 함유하는 약제학적 조성물

1990
- 1990-05-31 US US07/531,270 patent/US5077388A/en not_active Expired - Fee Related
1991
- 1991-01-04 CA CA002084186A patent/CA2084186C/en not_active Expired - Fee Related
- 1991-01-04 AT AT91903451T patent/ATE136552T1/de not_active IP Right Cessation
- 1991-01-04 DE DE69118696T patent/DE69118696T2/de not_active Expired - Fee Related
- 1991-01-04 EP EP91903451A patent/EP0537148B1/de not_active Expired - Lifetime
- 1991-01-04 WO PCT/US1991/000006 patent/WO1991018919A1/en not_active Ceased
- 1991-01-04 DK DK91903451.2T patent/DK0537148T3/da active
- 1991-01-04 NZ NZ236699A patent/NZ236699A/en unknown
- 1991-01-04 AU AU72220/91A patent/AU659993B2/en not_active Ceased
- 1991-01-04 ES ES91903451T patent/ES2085986T3/es not_active Expired - Lifetime
- 1991-01-04 JP JP3503528A patent/JP2573767B2/ja not_active Expired - Lifetime
- 1991-01-04 IL IL96880A patent/IL96880A0/xx unknown
- 1991-01-04 IE IE2791A patent/IE73668B1/en not_active IP Right Cessation
- 1991-01-04 MY MYPI91000007A patent/MY130013A/en unknown
- 1991-01-04 ZA ZA9193A patent/ZA9193B/xx unknown
1996
- 1996-04-22 GR GR960401088T patent/GR3019705T3/el unknown

Also Published As

Publication number	Publication date
MY130013A (en)	2007-05-31
IE910027A1 (en)	1991-12-04
US5077388A (en)	1991-12-31
WO1991018919A1 (en)	1991-12-12
CA2084186A1 (en)	1991-12-01
GR3019705T3 (en)	1996-07-31
NZ236699A (en)	1992-08-26
ES2085986T3 (es)	1996-06-16
DE69118696D1 (de)	1996-05-15
AU659993B2 (en)	1995-06-08
JPH05505934A (ja)	1993-09-02
ATE136552T1 (de)	1996-04-15
IL96880A0 (en)	1992-03-29
IE73668B1 (en)	1997-07-02
CA2084186C (en)	1999-12-14
DK0537148T3 (da)	1996-05-06
DE69118696T2 (de)	1996-08-29
EP0537148A1 (de)	1993-04-21
AU7222091A (en)	1991-12-31
EP0537148B1 (de)	1996-04-10
JP2573767B2 (ja)	1997-01-22

Similar Documents

Publication	Publication Date	Title
MY103892A (en)	1993-10-30	Interleukin-2 of high purity production and use
NZ210427A (en)	1988-09-29	Process for purifying blood clotting factor (factor viii:c); pharmaceutical compositions
GB8824869D0 (en)	1988-11-30	Synthetic antibody
BE892846A (fr)	1982-10-14	Procede de purification de substance physiologiquement active a activite antitumorale, et substance ainsi obtenue
IL96880A0 (en)	1992-03-29	Purification of human interleukin-4 from a secreted escherichia coli mutant
SE8005498L (sv)	1981-02-01	Homogent fibroblastinterferon och framstellning derav
DE69027995D1 (de)	1996-09-05	Reinigungsverfahren von transformierendem wachstumsfaktor (tgf)
JPS6344883A (ja)	1988-02-25	新規なヒアルロニダ−ゼｓｄ−６７８およびその製造法
GB2099008B (en)	1985-01-30	Enzymatic process for the treatment of xanthan gums to improve the filtrability of their aqueous solutions
EP0152346A3 (en)	1986-09-10	Method for purifying gamma-interferon
GR3029696T3 (en)	1999-06-30	Method of preparing a radioactive rhenium complex solution.
AU1239495A (en)	1995-06-01	An electrophoretic method to assess human cerebrospinal fluid
EP0446850B1 (de)	1996-01-24	Verfahren zur Herstellung von rekombinantem Humaninterferon-beta in reiner Form
FR2547814B1 (fr)	1985-10-18	Derives de l'acide bicyclo (3.2.1.) octane carboxylique, leur procede de preparation et leur application therapeutique
FR2583751B1 (fr)	1989-10-13	Nouveaux antibacteriens contenant des derives des acides oxo-4-pyridine carboxyliques et leur procede de preparation
Murooka et al.	1977	Affinity chromatography of Klebsiella arylsulfatase on tyrosyl-hexamethylenediamino-β-1, 3-glucan and immunoadsorbent
ES8304150A1 (es)	1983-02-16	"un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral".
JPS5599191A (en)	1980-07-28	Purification of kallikrein in human urine
SU1187826A1 (ru)	1985-10-30	Способ получени плазминогена
RU96102282A (ru)	1998-05-10	Способ терапии поллиноза
JPS57140726A (en)	1982-08-31	Purification of physiologically active substance having carcinostatic action
DK163582A (da)	1983-10-08	Fremgangsmaade til rensning af et fysiologisk aktivt stof med antitumorvirkning
FR2104732A1 (en)	1972-04-21	Asparaginase purification using asparagine in - hibitors coupled to carbohydrate matrix
Varghese et al.	1978	Hemolysin of Myxococcus fulvus NK 35: I. Production and Isolation
Allen et al.	1972	Amylolytic isoenzymes of Thermoactinomyces vulgaris