ZA925522B - Stable compositions for parenteral administration and their use - Google Patents

Stable compositions for parenteral administration and their use

Info

Publication number: ZA925522B
Authority: ZA; South Africa
Prior art keywords: compounds; parenteral administration; lambda; warm; alpha
Prior art date: 1991-07-23

Application number

ZA925522A

Other languages

English (en)

Inventor

Susan Mancini Cady

William David Steber

Phillip Wayne Hayes

Mary Ehlers Doscher

Kurt Allen Schwinghammer

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-23

Filing date

1992-07-22

Publication date

1993-04-28

1992-07-22 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1993-04-28 Publication of ZA925522B publication Critical patent/ZA925522B/xx

Links

239000000203 mixture Substances 0.000 title abstract 5
238000007911 parenteral administration Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 4
241001465754 Metazoa Species 0.000 abstract 2
YNFMRVVYUVPIAN-UHFFFAOYSA-N nemadectin alpha Natural products C1C(O)C(C)C(C(C)=CC(C)C)OC11OC(CC=C(C)CC(C)C=CC=C2C3(C(C(=O)O4)C=C(C)C(O)C3OC2)O)CC4C1 YNFMRVVYUVPIAN-UHFFFAOYSA-N 0.000 abstract 2
241000238421 Arthropoda Species 0.000 abstract 1
241000244206 Nematoda Species 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000003963 antioxidant agent Substances 0.000 abstract 1
230000003078 antioxidant effect Effects 0.000 abstract 1
RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical class C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 1
239000008280 blood Substances 0.000 abstract 1
210000004369 blood Anatomy 0.000 abstract 1
235000014113 dietary fatty acids Nutrition 0.000 abstract 1
229930195729 fatty acid Natural products 0.000 abstract 1
239000000194 fatty acid Substances 0.000 abstract 1
150000004665 fatty acids Chemical class 0.000 abstract 1
244000000013 helminth Species 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000004005 microsphere Substances 0.000 abstract 1
FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Chemical class COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 abstract 1
YNFMRVVYUVPIAN-AQUURSMBSA-N nemadectin Chemical compound C1[C@H](O)[C@H](C)[C@@H](C(/C)=C/C(C)C)O[C@]11O[C@H](C\C=C(C)\C[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 YNFMRVVYUVPIAN-AQUURSMBSA-N 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Tropical Medicine & Parasitology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

ZA925522A 1991-07-23 1992-07-22 Stable compositions for parenteral administration and their use ZA925522B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US73443091A	1991-07-23	1991-07-23

Publications (1)

Publication Number	Publication Date
ZA925522B true ZA925522B (en)	1993-04-28

Family

ID=24951666

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA925522A ZA925522B (en)	1991-07-23	1992-07-22	Stable compositions for parenteral administration and their use

Country Status (21)

Country	Link
US (1)	US6340671B1 (fr)
EP (1)	EP0525307B1 (fr)
JP (1)	JP3470904B2 (fr)
KR (1)	KR100235550B1 (fr)
CN (1)	CN1046852C (fr)
AT (1)	ATE134873T1 (fr)
AU (1)	AU651229B2 (fr)
BR (1)	BR9202771A (fr)
CA (1)	CA2074348C (fr)
DE (1)	DE69208765T2 (fr)
DK (1)	DK0525307T3 (fr)
ES (1)	ES2086022T3 (fr)
GR (1)	GR3019234T3 (fr)
HK (1)	HK1000005A1 (fr)
HU (1)	HU220595B1 (fr)
IE (1)	IE74401B1 (fr)
IL (1)	IL102567A (fr)
MX (1)	MX9204135A (fr)
NZ (1)	NZ243619A (fr)
TW (1)	TW201696B (fr)
ZA (1)	ZA925522B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5733566A (en) *	1990-05-15	1998-03-31	Alkermes Controlled Therapeutics Inc. Ii	Controlled release of antiparasitic agents in animals
US5643595A (en) *	1992-11-24	1997-07-01	Alkermes Controlled Therapeutics Inc. Ii	Growth promoters for animals
DE4308282C2 (de) *	1993-03-16	1994-12-22	Beiersdorf Ag	Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices
DE19613972A1 (de) *	1996-04-09	1997-10-16	Bayer Ag	Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
DE19638045A1 (de) *	1996-09-18	1998-03-19	Bayer Ag	Injektionsformulierungen von Avermectinen und Milbemycinen
TR200103188T2 (tr) *	1999-05-07	2002-04-22	Pharmasol Gmbh	Sıvı ve katı lipit karışımları temelli lipid parçacıklar.
US8663692B1 (en) *	1999-05-07	2014-03-04	Pharmasol Gmbh	Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
DE60133706T2 (de) *	2000-10-10	2009-07-02	Wyeth Holdings Corp.	Stabilisierte Arzneizusammensetzungen zur parenteralen Vearbreichung
FR2852843B1 (fr)	2003-03-24	2008-05-23	Karim Ioualalen	Systeme galenique permettant le masquage du gout
NZ534939A (en) *	2004-08-26	2007-04-27	Bomac Research Ltd	Injectable formulation comprising an anthelmintic compound with complexing compound for improved solubility
MX2012004133A (es)	2009-10-07	2012-05-08	Wyeth Llc	Composiciones que comprenden adyuvante, macrolido y antigeno proteico y procedimientos de uso de las mismas.
ITUB20153652A1 (it) *	2015-09-16	2017-03-16	Fatro Spa	Microsfere contenenti lattoni macrociclici antielminitici
HUE065367T2 (hu)	2017-04-13	2024-05-28	Ceva Sante Animale	Parazitafertõzések kezelésére használható injektálható anyag
BR112021016432A2 (pt)	2019-02-21	2021-11-09	Chromadex Inc	Composição que compreende prills de cera, processo para produzir prills de cera, composição nutricional, alimento, bebida ou suplemento alimentar que compreende prills de cera, e composição que compreende microesferas encapsuladas
EP3962448A1 (fr)	2019-05-03	2022-03-09	Intervet International B.V.	Compositions pharmaceutiques injectables et leurs utilisations
AU2021277491B2 (en)	2020-05-20	2024-05-16	Intervet International B.V.	Injectable pharmaceutical compositions and uses thereof
WO2022263505A1 (fr) *	2021-06-16	2022-12-22	Société des Produits Nestlé S.A.	Procédés d'enrobage d'un principe actif par une cire en phase solide
US20260014227A1 (en)	2022-06-30	2026-01-15	Virbac	Deslorelin use in chemical castration of a non-human mammal related to pk/pd interaction
WO2025190964A1 (fr)	2024-03-12	2025-09-18	Virbac	Modoflaner parentéral pour la lutte contre les ectoparasites
US20260021076A1 (en)	2024-07-22	2026-01-22	Zoetis Services Llc	Isoxazoline and macrocyclic lactone microspheres
WO2026041795A1 (fr)	2024-08-23	2026-02-26	Intervet International B.V.	Composition vétérinaire injectable pour bétail

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3659022A (en) *	1967-11-13	1972-04-25	Upjohn Co	Methods of preventing impregnation
US4144352A (en) *	1977-12-19	1979-03-13	Merck & Co., Inc.	Milbemycin compounds as anthelmintic agents
US5106994A (en) *	1984-06-05	1992-04-21	American Cyanamid Company	Agents and method of production thereof
US5169956A (en) *	1984-06-05	1992-12-08	American Cyanamid Company	Macrolide antibiotic compounds
ES2039219T3 (es) *	1986-08-11	1993-09-16	American Cyanamid Company	Composiciones para administracion parenteral y su uso.
GB8803836D0 (en) *	1988-02-18	1988-03-16	Glaxo Group Ltd	Compositions
DK0385106T3 (da) *	1989-02-28	1994-04-11	American Cyanamid Co	Bolus med forhalet frigivelse effektiv til forlænget prævention eller behandling af eller kontrol med nematode-, mide- og endo- og ektoparasitiske infektioner hos drøvtyggere
US5213810A (en) *	1990-03-30	1993-05-25	American Cyanamid Company	Stable compositions for parenteral administration and method of making same
US5192546A (en) *	1991-01-15	1993-03-09	Mycogen Corporation	Synergistic pesticidal compositions
US5346698A (en) *	1991-01-15	1994-09-13	Mycogen Corporation	Synergistic pesticidal compositions
US5185108A (en) *	1991-07-10	1993-02-09	The B. F. Goodrich Company	Method for producing wax microspheres
JP4654917B2 (ja)	2006-01-12	2011-03-23	日産自動車株式会社	車体後部構造

1992
- 1992-04-29 DE DE69208765T patent/DE69208765T2/de not_active Expired - Lifetime
- 1992-04-29 AT AT92107277T patent/ATE134873T1/de active
- 1992-04-29 EP EP92107277A patent/EP0525307B1/fr not_active Expired - Lifetime
- 1992-04-29 ES ES92107277T patent/ES2086022T3/es not_active Expired - Lifetime
- 1992-04-29 DK DK92107277.3T patent/DK0525307T3/da active
- 1992-05-16 TW TW081103831A patent/TW201696B/zh not_active IP Right Cessation
- 1992-06-30 CN CN92105395A patent/CN1046852C/zh not_active Expired - Lifetime
- 1992-07-15 MX MX9204135A patent/MX9204135A/es unknown
- 1992-07-20 JP JP21325992A patent/JP3470904B2/ja not_active Expired - Lifetime
- 1992-07-20 NZ NZ243619A patent/NZ243619A/en unknown
- 1992-07-20 BR BR929202771A patent/BR9202771A/pt not_active Application Discontinuation
- 1992-07-21 CA CA002074348A patent/CA2074348C/fr not_active Expired - Lifetime
- 1992-07-21 IL IL10256792A patent/IL102567A/en not_active IP Right Cessation
- 1992-07-22 AU AU20472/92A patent/AU651229B2/en not_active Expired
- 1992-07-22 HU HU9202404A patent/HU220595B1/hu unknown
- 1992-07-22 ZA ZA925522A patent/ZA925522B/xx unknown
- 1992-07-22 IE IE922373A patent/IE74401B1/en not_active IP Right Cessation
- 1992-07-22 KR KR1019920013077A patent/KR100235550B1/ko not_active Expired - Lifetime
1994
- 1994-06-22 US US08/263,574 patent/US6340671B1/en not_active Expired - Lifetime
1996
- 1996-03-07 GR GR950402159T patent/GR3019234T3/el unknown
1997
- 1997-07-09 HK HK97101523A patent/HK1000005A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR930001904A (ko)	1993-02-22
JP3470904B2 (ja)	2003-11-25
NZ243619A (en)	1994-12-22
KR100235550B1 (ko)	1999-12-15
CN1068735A (zh)	1993-02-10
ATE134873T1 (de)	1996-03-15
HU9202404D0 (en)	1992-10-28
HK1000005A1 (en)	1997-10-03
EP0525307B1 (fr)	1996-03-06
DE69208765T2 (de)	1996-09-26
TW201696B (fr)	1993-03-11
BR9202771A (pt)	1993-03-23
EP0525307A1 (fr)	1993-02-03
HUT62454A (en)	1993-05-28
AU2047292A (en)	1993-01-28
CA2074348C (fr)	2004-02-17
DK0525307T3 (da)	1996-04-01
ES2086022T3 (es)	1996-06-16
IL102567A (en)	1996-10-31
HU220595B1 (hu)	2002-03-28
DE69208765D1 (de)	1996-04-11
IE74401B1 (en)	1997-07-30
JPH05194211A (ja)	1993-08-03
US6340671B1 (en)	2002-01-22
CA2074348A1 (fr)	1993-01-24
MX9204135A (es)	1993-01-01
CN1046852C (zh)	1999-12-01
IE922373A1 (en)	1993-01-27
GR3019234T3 (en)	1996-06-30
IL102567A0 (en)	1993-01-14
AU651229B2 (en)	1994-07-14

Publication	Publication Date	Title
IL102567A0 (en)	1993-01-14	Stable compositions for parenteral administration and their use
Shiau et al.	2002	Vitamin E sparing effect by dietary vitamin C in juvenile hybrid tilapia, Oreochromis niloticus× O. aureus
CY1108145T1 (el)	2013-03-13	Σταθερες συνθεσεις για παρεντερικη χορηγηση
DE69734253D1 (de)	2006-02-02	Arzneizusammensetzungen enthaltend Rapamycinderivate
YU23599A (sh)	2001-07-10	Stabilizovani antihistaminski sirup
KR920007629A (ko)	1992-05-27	SALMe염, 5-MTHF 및 5-FTHF 중에서 선택된 화합물 적어도 1개를 유효성분으로서 함유하여 AIDS환자의 신경학적 질환치료시 활성을 나타내는 약제학적 조성물
EP0146414A2 (fr)	1985-06-26	Formulation non-aqueuse antiparasitaire contenant une avermectine ou une milbémycine
IL102814A0 (en)	1993-01-31	Pyrazine derivatives,their preparation and pharmaceutical compositions comprising them
DK0535734T3 (da)	1999-08-09	Langtidsvirkende injicerbare formuleringer indeholdende hydrogeneret castorolie
KR900006330A (ko)	1990-05-07	피롤로[3,2-e]피라졸로[1,5-a]피리미딘 유도체 및 이를 함유하는 약제
KR890005088A (ko)	1989-05-11	4- 아미노피리딘 유도체 및 그의 산 부가염
CY1112057T1 (el)	2015-11-04	Θεραπευτικος παραγων για διαταραχη επαρκειας τροφης στο στομαχι
ATE207492T1 (de)	2001-11-15	Difluoroavermectin-derivate
ATE285771T1 (de)	2005-01-15	Diaminotrifluoromethylpyrimidinderivate enthaltende antikrebs-zusammensetzung
KR950703956A (ko)	1995-11-17	순환 장애 개선제[circulatory disturbance ameliorant]
WO2001072289A3 (fr)	2002-04-18	Medicament pour stimuler la leucopoese, pour traiter des affections tumorales et des protozooses, l'acarinose, l'arthropodiase et procedes permettant de le produire
DK1100463T3 (da)	2003-01-20	Injicerbare formuleringer indeholdende ramoplanin
CA2239053A1 (fr)	1997-06-26	Derives d'ethane diphenyle pyridyle utilises comme inhibiteurs de pde iv
JPS5480426A (en)	1979-06-27	Agent for prophylaxis and remedy of mycoplasmosis
KR830006182A (ko)	1983-09-20	신규한 옥시아세트산 유도체, 그의 제법 및 그것을 유효성분으로 하는 혈중지질 저하제(血中脂質低下劑)