ZA926837B - A pharmaceutical composition for and a method of using a combination of an uricosuric agent and an EAA antagonist - Google Patents

A pharmaceutical composition for and a method of using a combination of an uricosuric agent and an EAA antagonist

Info

Publication number: ZA926837B
Authority: ZA; South Africa
Prior art keywords: combination; pharmaceutical composition; uricosuric agent; eaa antagonist; antagonist
Prior art date: 1991-09-09

Application number

ZA926837A

Other languages

English (en)

Inventor

Christopher Franklin Bigge

Graham Johnson

Charles Price Taylor Jr

Devind Franklin Welty

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-09

Filing date

1992-09-08

Publication date

1994-03-08

1992-09-08 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1994-03-08 Publication of ZA926837B publication Critical patent/ZA926837B/xx

Links

229940116731 Uricosuric agent Drugs 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
239000003383 uricosuric agent Substances 0.000 title abstract 2
239000005557 antagonist Substances 0.000 title 1
239000003194 amino acid receptor blocking agent Substances 0.000 abstract 2
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
DBABZHXKTCFAPX-UHFFFAOYSA-N probenecid Chemical compound CCCN(CCC)S(=O)(=O)C1=CC=C(C(O)=O)C=C1 DBABZHXKTCFAPX-UHFFFAOYSA-N 0.000 abstract 1
229960003081 probenecid Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA926837A 1991-09-09 1992-09-08 A pharmaceutical composition for and a method of using a combination of an uricosuric agent and an EAA antagonist ZA926837B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US75640191A	1991-09-09	1991-09-09

Publications (1)

Publication Number	Publication Date
ZA926837B true ZA926837B (en)	1994-03-08

Family

ID=25043303

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA926837A ZA926837B (en)	1991-09-09	1992-09-08	A pharmaceutical composition for and a method of using a combination of an uricosuric agent and an EAA antagonist

Country Status (16)

Country	Link
US (4)	US5407935A (de)
EP (1)	EP0603301B1 (de)
JP (1)	JP3218038B2 (de)
AT (1)	ATE162075T1 (de)
AU (1)	AU660717B2 (de)
CA (1)	CA2115442C (de)
DE (1)	DE69224069T2 (de)
DK (1)	DK0603301T3 (de)
ES (1)	ES2113957T3 (de)
GR (1)	GR3026369T3 (de)
MX (1)	MX9205127A (de)
NO (1)	NO307645B1 (de)
NZ (1)	NZ244243A (de)
PT (1)	PT100850B (de)
WO (1)	WO1993004688A1 (de)
ZA (1)	ZA926837B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993004688A1 (en) *	1991-09-09	1993-03-18	Warner-Lambert Company	Pharmaceutical preparation containing an uricosuric and an excitatory amino acid antagonist
US5318985A (en) *	1991-12-20	1994-06-07	Merrell Dow Pharmaceuticals Inc.	Potentiation of NMDA antagonists
US5854217A (en)	1992-09-28	1998-12-29	Bearsden Bio, Inc.	Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function
JPH07505908A (ja) *	1992-09-28	1995-06-29	マックセチーニ、マリア　ルイザ	Ｎｍｄａ受容体のアロステリックモジュレーター
EP0964691A4 (de)	1996-07-22	2002-10-30	Cognetix Inc	Verwendung von conantokine
US6515103B1 (en)	1996-07-22	2003-02-04	University Of Utah Research Foundation	Conantokins
US6277825B1 (en)	1996-07-22	2001-08-21	University Of Utah Research Foundation	Use of conantokins for treating pain
IL125950A0 (en) *	1997-09-05	1999-04-11	Pfizer Prod Inc	Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
EP1082113A2 (de) *	1998-05-26	2001-03-14	Peter Louis Carlen	Zusammensetzungen und verfahren zur verminderung von behinderter mentaler funktion, gedächtnisschwund und zur verkürzung der erholungszeit nach der narkose bei zaügetieren
US6399574B1 (en)	2000-03-22	2002-06-04	University Of Utah Research Foundation	Use of conantokins
JP2004517804A (ja)	2000-06-28	2004-06-17	メルク・アンド・カンパニー・インコーポレーテッド	心臓血管病の治療法
US20080051428A1 (en) *	2002-05-15	2008-02-28	Davis Paul J	Pyrroloquinoline quinone drugs and methods of use thereof
US7276514B2 (en) *	2002-05-15	2007-10-02	Charitable Leadership Foundation - Medical Technology Acceleration Program	Pyrroloquinoline quinone drugs for treatment of cardiac injury and methods of use thereof
US20040152694A1 (en) *	2003-02-04	2004-08-05	Istvan Kurucz	Methods and compositions for treating inflammatory disorders of the airways
US20050209317A1 (en) *	2004-03-22	2005-09-22	Apkarian A V	Method and compositions for treatment of chronic neuropathic pain
US8461223B2 (en)	2005-04-07	2013-06-11	Aspen Aerogels, Inc.	Microporous polycyclopentadiene-based aerogels
ITFI20050083A1 (it) *	2005-04-29	2006-10-30	Univ Firenze	Uso dell'acido chinurenico per la prevenzione e il trattamento dello shock
EP1883405A4 (de)	2005-05-09	2010-01-27	Takeda Pharmaceuticals North A	Verfahren zur behandlung von nephrolithiase
WO2007140293A2 (en)	2006-05-25	2007-12-06	Aspen Aerogels, Inc.	Aerogel compositions with enhanced performance
EP2338492A1 (de)	2009-12-24	2011-06-29	Universidad del Pais Vasco	Verfahren und Zusammensetzung zur Behandlung von Alzheimer
CA2812034C (en)	2010-09-10	2018-10-23	Takeda Pharmaceuticals U.S.A., Inc.	Methods for concomitant treatment of theophylline and febuxostat
US10806711B2 (en)	2011-08-12	2020-10-20	University Of Cincinnati	Method of treating acute decompensated heart failure with probenecid
MX376077B (es)	2013-03-13	2025-03-07	Univ Cincinnati	Tratamiento de una disfuncion cardiaca diastolica con un agonista del receptor trpv2.
US20170143681A1 (en)	2015-11-02	2017-05-25	Apkarian Technologies Llc	Methods and compositions for treating pain
EP3427729A1 (de) *	2017-07-13	2019-01-16	Paris Sciences et Lettres - Quartier Latin	Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4812458A (en) *	1986-09-16	1989-03-14	A/S Ferrosan	6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics
DK146787A (da) *	1987-03-23	1988-09-24	Ferrosan	Heterocykliske forbindelser, deres fremstilling og anvendelse
AU643365B2 (en) *	1991-02-28	1993-11-11	Aventisub Ii Inc.	NMDA antagonists
WO1993004688A1 (en) *	1991-09-09	1993-03-18	Warner-Lambert Company	Pharmaceutical preparation containing an uricosuric and an excitatory amino acid antagonist

1992
- 1992-09-02 WO PCT/US1992/007540 patent/WO1993004688A1/en not_active Ceased
- 1992-09-02 DE DE69224069T patent/DE69224069T2/de not_active Expired - Fee Related
- 1992-09-02 ES ES92919882T patent/ES2113957T3/es not_active Expired - Lifetime
- 1992-09-02 CA CA002115442A patent/CA2115442C/en not_active Expired - Fee Related
- 1992-09-02 AU AU25943/92A patent/AU660717B2/en not_active Ceased
- 1992-09-02 EP EP92919882A patent/EP0603301B1/de not_active Expired - Lifetime
- 1992-09-02 AT AT92919882T patent/ATE162075T1/de not_active IP Right Cessation
- 1992-09-02 JP JP50544593A patent/JP3218038B2/ja not_active Expired - Fee Related
- 1992-09-02 DK DK92919882T patent/DK0603301T3/da active
- 1992-09-07 NZ NZ244243A patent/NZ244243A/en unknown
- 1992-09-08 ZA ZA926837A patent/ZA926837B/xx unknown
- 1992-09-08 MX MX9205127A patent/MX9205127A/es not_active IP Right Cessation
- 1992-09-08 PT PT100850A patent/PT100850B/pt not_active IP Right Cessation
1993
- 1993-04-19 US US08/049,228 patent/US5407935A/en not_active Expired - Fee Related
1994
- 1994-03-08 NO NO940809A patent/NO307645B1/no not_active IP Right Cessation
1995
- 1995-10-05 US US08/539,398 patent/US5627168A/en not_active Expired - Fee Related
1996
- 1996-12-31 US US08/775,637 patent/US5767119A/en not_active Expired - Fee Related
1998
- 1998-03-13 GR GR980400554T patent/GR3026369T3/el unknown
- 1998-03-27 US US09/049,495 patent/US5942513A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5767119A (en)	1998-06-16
EP0603301B1 (de)	1998-01-14
CA2115442A1 (en)	1993-03-18
US5627168A (en)	1997-05-06
DE69224069T2 (de)	1998-07-02
NO307645B1 (no)	2000-05-08
US5942513A (en)	1999-08-24
PT100850A (pt)	1993-10-29
PT100850B (pt)	1999-07-30
NZ244243A (en)	1995-07-26
DE69224069D1 (de)	1998-02-19
EP0603301A1 (de)	1994-06-29
ES2113957T3 (es)	1998-05-16
NO940809D0 (no)	1994-03-08
AU2594392A (en)	1993-04-05
JPH06510544A (ja)	1994-11-24
JP3218038B2 (ja)	2001-10-15
DK0603301T3 (da)	1998-09-14
MX9205127A (es)	1993-07-01
AU660717B2 (en)	1995-07-06
CA2115442C (en)	2003-09-23
GR3026369T3 (en)	1998-06-30
NO940809L (no)	1994-03-08
WO1993004688A1 (en)	1993-03-18
US5407935A (en)	1995-04-18
ATE162075T1 (de)	1998-01-15

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