ZA9610874B - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number: ZA9610874B
Authority: ZA; South Africa
Prior art keywords: hydroxyl; lower alkoxy; chemical compounds; optionally hydroxylated; alkoxylated
Prior art date: 1995-12-21

Application number

ZA9610874A

Other languages

English (en)

Inventor

Robert Henry Hesse

Maurice Murdoch Pechet

Sundara Katugam Srinvasa Setty

Original Assignee

Res Inst Medicine Chem

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-21

Filing date

1996-12-23

Publication date

1997-06-18

1996-12-23 Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem

1997-06-18 Publication of ZA9610874B publication Critical patent/ZA9610874B/xx

Links

150000001875 compounds Chemical class 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000000304 alkynyl group Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
XMDLIEZJERQGEY-ZHFUSYIKSA-N (1r,3s,5z)-5-[(2e)-2-[(1s,3as,7ar)-1-ethyl-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)CC)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C XMDLIEZJERQGEY-ZHFUSYIKSA-N 0.000 abstract 1
230000003509 anti-fertility effect Effects 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
230000000118 anti-neoplastic effect Effects 0.000 abstract 1
230000001028 anti-proliverative effect Effects 0.000 abstract 1
239000003418 antiprogestin Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
230000001506 immunosuppresive effect Effects 0.000 abstract 1
229940125721 immunosuppressive agent Drugs 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
230000003623 progesteronic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)

ZA9610874A 1995-12-21 1996-12-23 Chemical compounds ZA9610874B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9526208.5A GB9526208D0 (en)	1995-12-21	1995-12-21	Chemical compounds

Publications (1)

Publication Number	Publication Date
ZA9610874B true ZA9610874B (en)	1997-06-18

Family

ID=10785847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9610874A ZA9610874B (en)	1995-12-21	1996-12-23	Chemical compounds

Country Status (21)

Country	Link
US (2)	US6372926B2 (de)
EP (1)	EP0874815B1 (de)
JP (1)	JP2000503636A (de)
KR (1)	KR19990076664A (de)
CN (1)	CN1086694C (de)
AT (1)	ATE200663T1 (de)
AU (1)	AU710680B2 (de)
CA (1)	CA2241011A1 (de)
CZ (1)	CZ290930B6 (de)
DE (1)	DE69612568T2 (de)
DK (1)	DK0874815T3 (de)
ES (1)	ES2155948T3 (de)
GB (1)	GB9526208D0 (de)
GR (1)	GR3036132T3 (de)
HU (1)	HUP9903786A3 (de)
IL (1)	IL125027A0 (de)
NO (1)	NO982816L (de)
NZ (1)	NZ324775A (de)
PT (1)	PT874815E (de)
WO (1)	WO1997023453A1 (de)
ZA (1)	ZA9610874B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2481909C (en) *	2002-04-11	2013-07-02	Instytut Farmaceutyczny	Preparation of 24-alkyl analogs of cholecalciferol
US7253293B2 (en) *	2004-01-06	2007-08-07	Andrzej Slominski	Enzymatic method to produce 7-dehydropregnenolone, vitamin D3-like compounds and derivatives thereof
WO2006115509A2 (en)	2004-06-24	2006-11-02	Novartis Vaccines And Diagnostics Inc.	Small molecule immunopotentiators and assays for their detection
CA2601545A1 (en) *	2005-03-23	2006-09-28	Bioxell S.P.A.	Use of vitamin d compounds to treat endometriosis
TW200714580A (en) *	2005-10-14	2007-04-16	Formosa Lab Inc	Process for preparing vitamin D analogs
EA201691980A1 (ru)	2009-01-27	2017-07-31	БЕРГ ЭлЭлСи	Способы уменьшения побочных эффектов, связанных с химиотерапией
CN102655869B (zh)	2009-08-14	2016-08-10	博格有限责任公司	用于治疗脱发的维生素d3及其类似物
JP5563324B2 (ja) *	2010-02-03	2014-07-30	フォーモサ・ラボラトリーズ・インコーポレーテッド	マキサカルシトール中間体およびその製造方法
WO2014194133A1 (en)	2013-05-29	2014-12-04	Berg Llc	Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6034543B2 (ja)	1977-07-01	1985-08-09	中外製薬株式会社	ビタミンｄ誘導体
GB9214202D0 (en)	1992-07-03	1992-08-12	Leo Pharm Prod Ltd	Chemical compounds
GB9220439D0 (en) *	1992-09-28	1992-11-11	Leo Pharm Prod Ltd	Chemical compounds
US5397776A (en) *	1993-08-20	1995-03-14	Wisconsin Alumni Research Foundation	Vitamin D compounds with anti-progesterone activity

1995
- 1995-12-21 GB GBGB9526208.5A patent/GB9526208D0/en active Pending
1996
- 1996-12-23 AU AU12025/97A patent/AU710680B2/en not_active Ceased
- 1996-12-23 HU HU9903786A patent/HUP9903786A3/hu unknown
- 1996-12-23 IL IL12502796A patent/IL125027A0/xx not_active IP Right Cessation
- 1996-12-23 ZA ZA9610874A patent/ZA9610874B/xx unknown
- 1996-12-23 JP JP9523433A patent/JP2000503636A/ja not_active Ceased
- 1996-12-23 US US09/051,483 patent/US6372926B2/en not_active Expired - Fee Related
- 1996-12-23 CA CA002241011A patent/CA2241011A1/en not_active Abandoned
- 1996-12-23 CZ CZ19981947A patent/CZ290930B6/cs not_active IP Right Cessation
- 1996-12-23 EP EP96943236A patent/EP0874815B1/de not_active Expired - Lifetime
- 1996-12-23 PT PT96943236T patent/PT874815E/pt unknown
- 1996-12-23 WO PCT/GB1996/003218 patent/WO1997023453A1/en not_active Ceased
- 1996-12-23 ES ES96943236T patent/ES2155948T3/es not_active Expired - Lifetime
- 1996-12-23 KR KR1019980704776A patent/KR19990076664A/ko not_active Ceased
- 1996-12-23 DK DK96943236T patent/DK0874815T3/da active
- 1996-12-23 AT AT96943236T patent/ATE200663T1/de not_active IP Right Cessation
- 1996-12-23 DE DE69612568T patent/DE69612568T2/de not_active Expired - Fee Related
- 1996-12-23 NZ NZ324775A patent/NZ324775A/xx unknown
- 1996-12-23 CN CN96180032A patent/CN1086694C/zh not_active Expired - Fee Related
1998
- 1998-06-18 NO NO982816A patent/NO982816L/no not_active Application Discontinuation
2001
- 2001-06-27 GR GR20010400985T patent/GR3036132T3/el not_active IP Right Cessation
2002
- 2002-03-07 US US10/091,594 patent/US20020188142A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20020188142A1 (en)	2002-12-12
ES2155948T3 (es)	2001-06-01
CN1086694C (zh)	2002-06-26
HUP9903786A2 (hu)	2000-03-28
AU710680B2 (en)	1999-09-30
GR3036132T3 (en)	2001-09-28
CA2241011A1 (en)	1997-07-03
AU1202597A (en)	1997-07-17
JP2000503636A (ja)	2000-03-28
EP0874815B1 (de)	2001-04-18
KR19990076664A (ko)	1999-10-15
GB9526208D0 (en)	1996-02-21
CZ290930B6 (cs)	2002-11-13
NZ324775A (en)	1999-02-25
DE69612568T2 (de)	2001-09-06
US20020010163A1 (en)	2002-01-24
DE69612568D1 (de)	2001-05-23
DK0874815T3 (da)	2002-03-04
EP0874815A1 (de)	1998-11-04
CZ194798A3 (cs)	1998-11-11
PT874815E (pt)	2001-07-31
CN1209120A (zh)	1999-02-24
WO1997023453A1 (en)	1997-07-03
HUP9903786A3 (en)	2000-09-28
NO982816L (no)	1998-08-21
IL125027A0 (en)	1999-01-26
ATE200663T1 (de)	2001-05-15
NO982816D0 (no)	1998-06-18
US6372926B2 (en)	2002-04-16

Publication	Publication Date	Title
AU1497997A (en)	1997-09-04	Use of estrogen antagonists and estrogen agonists in inhibiting pathological conditions
CA2223513A1 (en)	1996-12-12	Betulinic acid derivatives and uses therefor
TR199902357T2 (xx)	2000-05-22	Yeni bile�imler.
LV12618A (en)	2001-02-20	Use of sulphamate derivatives as steroid sulphatase inhibitors
NZ331941A (en)	2000-04-28	Pentafluorobenzenesulfonamides and analogs and use in regulation of LDL receptor synthesis
ES2104090T3 (es)	1997-10-01	Nuevas 3',5'-di-t-butil-4'-hidroxi-flavonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
IT1271325B (it)	1997-05-27	Composti diastereomericamente puri derivati da 3-oxo e 3-tioxo-4-azaandrostani e loro uso come antiandrogeni
GB9526208D0 (en)	1996-02-21	Chemical compounds
AU3744397A (en)	1998-02-25	Total synthesis of antitumor acylfulvenes
NO20002676L (no)	2000-05-25	Androgene steroidforbindelser og en fremgangsmÕte for fremstilling og anvendelse av samme
MX9806211A (es)	1998-10-31	Composiciones herbicidas estables que contienen quelados metalicos de compuestos herbicidas de dionas.
CA2385200A1 (en)	2001-04-12	4-hydroxybiphenyl hydrazide derivatives
DK0755922T3 (da)	2000-11-13	22-Thiavitamin D3-derivat
EP0605728A4 (de)	1995-05-03	Chromonderivate und diese als aktivbestandteile enthaltende aldose reduktase-inhibitoren.
FR2706893B1 (de)	1995-08-04
AU2549099A (en)	1999-09-15	24-hydroxyvitamin d derivatives
CA2245537A1 (en)	1997-08-07	Stable herbicidal compositions containing metal chelates of herbicidal dione compounds
NO307139B1 (no)	2000-02-14	Fremgangmåte ved fremstilling av 5,6-dihydroksy-2-amino- 1,2,3,4-tetrahydronaftalenderivater
CA2032311A1 (en)	1991-06-21	2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase and 19-hydroxylase inhibitors
MX9604735A (es)	1998-01-31	Derivados de la 22-tiavitamina d3.
EP0609457A4 (en)	1994-08-24	Benzene derivative.
AU2148899A (en)	1999-06-16	15-methyl-cyclopropanosteroids and method for the production thereof
YU49004B (sh)	2003-04-30	LANOSTA-7,9-DIEN-3Гџ, 32-DIOL I POSTUPAK ZA NJEGOVO DOBIJANJE
TW349935B (en)	1999-01-11	Oxime ether compounds, their intermediates and their use as pesticides