ZA972599B - Use of bradykinin antagonists for the production of pharmaceuticals for the treatment of chronic fibrogenetic liver disorders and acute liver disorders. - Google Patents

Use of bradykinin antagonists for the production of pharmaceuticals for the treatment of chronic fibrogenetic liver disorders and acute liver disorders.

Info

Publication number
ZA972599B
ZA972599B ZA9702599A ZA972599A ZA972599B ZA 972599 B ZA972599 B ZA 972599B ZA 9702599 A ZA9702599 A ZA 9702599A ZA 972599 A ZA972599 A ZA 972599A ZA 972599 B ZA972599 B ZA 972599B
Authority
ZA
South Africa
Prior art keywords
liver disorders
pharmaceuticals
treatment
production
bradykinin antagonists
Prior art date
Application number
ZA9702599A
Other languages
English (en)
Inventor
Gerhard Breipohl
Stephan Henke
Jochen Knolle
Klaus Wirth
Max Hropot
Martin Bickel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA972599B publication Critical patent/ZA972599B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA9702599A 1996-03-27 1997-03-26 Use of bradykinin antagonists for the production of pharmaceuticals for the treatment of chronic fibrogenetic liver disorders and acute liver disorders. ZA972599B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19612067A DE19612067A1 (de) 1996-03-27 1996-03-27 Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen

Publications (1)

Publication Number Publication Date
ZA972599B true ZA972599B (en) 1997-09-29

Family

ID=7789557

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9702599A ZA972599B (en) 1996-03-27 1997-03-26 Use of bradykinin antagonists for the production of pharmaceuticals for the treatment of chronic fibrogenetic liver disorders and acute liver disorders.

Country Status (24)

Country Link
US (1) US5863901A (es)
EP (1) EP0797997B1 (es)
JP (1) JP4185169B2 (es)
KR (1) KR100453394B1 (es)
CN (1) CN1164421A (es)
AT (1) ATE297749T1 (es)
AU (1) AU1651697A (es)
BR (1) BR9701455A (es)
CA (1) CA2200040A1 (es)
CZ (1) CZ90797A3 (es)
DE (2) DE19612067A1 (es)
DK (1) DK0797997T3 (es)
ES (1) ES2242973T3 (es)
HR (1) HRP970171A2 (es)
HU (1) HUP9700642A3 (es)
ID (1) ID16413A (es)
IL (1) IL120521A0 (es)
NO (1) NO971453L (es)
PL (1) PL319193A1 (es)
PT (1) PT797997E (es)
SI (1) SI0797997T1 (es)
SK (1) SK39297A3 (es)
TR (1) TR199700228A2 (es)
ZA (1) ZA972599B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914236A1 (en) 2002-04-10 2008-04-23 Ortho-McNeil Pharmaceutical, Inc. Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators
TWI407960B (zh) 2007-03-23 2013-09-11 Jerini Ag 小分子緩激肽ｂ２受體調節劑
JP2011525194A (ja) * 2008-06-20 2011-09-15 キネメッド， インコーポレイテッド 線維性疾患または病態を治療するための組成物
AR113839A1 (es) 2017-11-24 2020-06-17 Pharvaris B V Antagonistas del receptor b2 de bradiquinina
AR118983A1 (es) 2019-05-23 2021-11-17 Pharvaris Gmbh Antagonistas cíclicos del receptor b2 de bradiquinina
UY38706A (es) 2019-05-23 2020-12-31 Pharvaris Gmbh Antagonistas cíclicos del receptor b2 de bradiquinina

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides
US4923963A (en) * 1987-09-02 1990-05-08 Nova Technology Limited Partnership Bradykinin antagonist peptides
WO1989009230A1 (en) * 1988-03-25 1989-10-05 Administrators Of The Tulane Educational Fund Therapeutic peptides
DE3926822A1 (de) * 1989-08-14 1991-02-21 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
IE63490B1 (en) * 1988-11-24 1995-05-03 Hoechst Ag Peptides having bradykinin antagonist action
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
EP0502987B1 (en) * 1989-12-08 1994-08-31 Trustees Of Boston University Acylated bradykinin antagonists and uses therefor
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
JPH06508116A (ja) * 1991-04-01 1994-09-14 コルテク，インコーポレイテッド ブラジキニンアンタゴニスト
DE69226708T2 (de) * 1991-04-19 1999-04-15 Scios Nova Inc., Mountain View, Calif. Bradykinin typische peptide
CA2106762C (en) * 1991-04-19 2000-10-10 Donald J. Kyle Bradykinin antagonist peptides
WO1993011789A1 (en) * 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides
FR2686343B1 (fr) * 1992-01-17 1994-03-11 Adir Cie Nouveaux derives pseudopeptidiques a activite antagoniste de la bradykinine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
TW258739B (es) * 1992-04-04 1995-10-01 Hoechst Ag
FR2692581B1 (fr) * 1992-06-18 1994-08-19 Adir Nouveaux dérivés peptidiques à activité antagoniste de la bradykinine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
AU5098593A (en) * 1992-09-11 1994-04-12 Lajos Gera Bradykinin antagonists containing aliphatic amino acids in the 5-position
US5521158A (en) * 1992-10-08 1996-05-28 Scios Nova Inc. Pseudopeptide bradykinin receptor antagonists
IL107400A0 (en) * 1992-11-10 1994-01-25 Cortech Inc Bradykinin antagonists
WO1994019372A1 (en) * 1993-02-17 1994-09-01 Scios Nova Inc. Cyclic bradykinin antagonist peptides
AU680870B2 (en) * 1993-04-28 1997-08-14 Astellas Pharma Inc. New heterocyclic compounds
JPH11500100A (ja) * 1993-09-09 1999-01-06 サイオス ノバ インコーポレイテッド 偽ペプチドおよび非ペプチドブラジキニンレセプターアンタゴニスト
DE4345062A1 (de) * 1993-12-31 1995-07-13 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von Viruserkrankungen
KR100360639B1 (ko) * 1994-03-09 2003-01-30 코르텍, 인크. N-치환글리신함유브라디키닌길항제펩티드

Also Published As

Publication number Publication date
PT797997E (pt) 2005-09-30
ES2242973T3 (es) 2005-11-16
EP0797997A2 (de) 1997-10-01
BR9701455A (pt) 1998-08-18
MX9702292A (es) 1997-09-30
HRP970171A2 (en) 1998-04-30
NO971453L (no) 1997-09-29
JP4185169B2 (ja) 2008-11-26
KR970064622A (ko) 1997-10-13
ATE297749T1 (de) 2005-07-15
US5863901A (en) 1999-01-26
JPH1017491A (ja) 1998-01-20
DE59712344D1 (de) 2005-07-21
EP0797997B1 (de) 2005-06-15
DE19612067A1 (de) 1997-10-02
HUP9700642A2 (hu) 1998-01-28
HU9700642D0 (en) 1997-05-28
SK39297A3 (en) 1997-10-08
TR199700228A2 (xx) 1997-10-21
NO971453D0 (no) 1997-03-26
IL120521A0 (en) 1997-07-13
CN1164421A (zh) 1997-11-12
EP0797997A3 (de) 2000-05-31
SI0797997T1 (en) 2005-10-31
KR100453394B1 (ko) 2004-12-30
PL319193A1 (en) 1997-09-29
AU1651697A (en) 1997-10-02
HUP9700642A3 (en) 1998-03-02
DK0797997T3 (da) 2005-10-17
ID16413A (id) 1997-09-25
CA2200040A1 (en) 1997-09-27
CZ90797A3 (en) 1997-10-15

Similar Documents

Publication Publication Date Title
IL128416A0 (en) Pharmaceutical composition for the treatment of alzheimer's disease
HUP0000558A3 (en) Use of active d vitamin analogues for producing pharmaceutical composition for the treatment of prostatic diseases
HU9701059D0 (en) Use of strontium salts for the production of pharmaceutical compositions intended for the treatment of arthrosis
BG102733A (en) New substituted cyclic amino acids as pharmaceutical forms
CA2260145A1 (en) Use of l-acetylcarnitine, l-isovalerylcarnitine, l-propionylcarnitine for increasing the levels of igf-1
HUP9700603A3 (en) Pharmaceutical preparation for the treatment of blood coagulation disorders
CA2100212A1 (en) Use of complement inhibitors for the preparation of a pharmaceutical for the prophylaxis and therapy of inflammatory intestinal and skin disorders as well as purpura
WO1998025930A3 (en) Use of bi- and tricyclic pyridone derivatives against alzheimer's disease
PL323798A1 (en) Application of derivatives of vitamin d4 in treating skin diseases
WO1999040883A3 (en) Compositions and methods for the treatment of cystic fibrosis
CA2266608A1 (en) Combination composition in the form of nutritional supplement or pharmaceutical composition for the prevention and therapeutical treatment of degenerative or inflammatory articular disorders
NO975234L (no) Fremgangsmåte for behandling av maniske og bipolare forstyrrelser
DE69424777D1 (de) 3,4-diarylchromane zur behandlung von dermatitis
IL120521A0 (en) Use of bradykinin antagonists for the production of pharmaceuticals for the treatment of chronic fibrogenetic liver disorders and acute liver disorders
PL338673A1 (en) Application of fanquinone in treating alzheimer disease
MY121604A (en) Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc together with azt
NZ303993A (en) Pharmaceutical compositions containing aminotetralin derivatives for treating cardiac disorders
CA2260863A1 (en) Treatment of psychotic disorders
ES2190499T3 (es) Uso de antagonistas de bradiquinina para la preparacion de medicamentos para el tratamiento y la prevencion de la enfermedad de alzheimer.
WO1990006116A3 (de) Mittel zur behandlung von chronisch entzündlichen darmerkrankungen
HUT71422A (en) Use of bradykinin-antagonists for producing pharmaceutical compositions for treating virus diseases
AU4016189A (en) Use of 2-azabicyclo(2.2.2) octane-3-carboxylic acid derivatives for the production of medicinal products intended for the treatment of diseases resulting from impairment of the vascular wall as well as for disorders of the microcirculation
ZA921101B (en) Use of tetra: Hydro-thieno-pyrido-indole derivatives for the prepartion of a medicine for the treatment of skin disorders.
ZA974415B (en) Use of nonpeptide bradykinin antagonists for the treatment and prevention of chronic fibrogenetic liver disorders, acute liver disorders and the complications associated therewith.
IT8522576A0 (it) Composizione farmaceutica per il trattamento di disturbi respiratori, muscolari e articolari.