ZA983740B - Novel amidine derivatives and their use in therapy - Google Patents

Novel amidine derivatives and their use in therapy

Info

Publication number
ZA983740B
ZA983740B ZA983740A ZA983740A ZA983740B ZA 983740 B ZA983740 B ZA 983740B ZA 983740 A ZA983740 A ZA 983740A ZA 983740 A ZA983740 A ZA 983740A ZA 983740 B ZA983740 B ZA 983740B
Authority
ZA
South Africa
Prior art keywords
therapy
amidine derivatives
novel amidine
novel
derivatives
Prior art date
Application number
ZA983740A
Other languages
English (en)
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA983740B publication Critical patent/ZA983740B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA983740A 1997-05-05 1998-05-04 Novel amidine derivatives and their use in therapy ZA983740B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds

Publications (1)

Publication Number Publication Date
ZA983740B true ZA983740B (en) 1999-02-19

Family

ID=20406836

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA983740A ZA983740B (en) 1997-05-05 1998-05-04 Novel amidine derivatives and their use in therapy

Country Status (28)

Country Link
US (1) US6166030A (da)
EP (1) EP0983266B1 (da)
JP (1) JP2001523263A (da)
KR (1) KR20010012227A (da)
CN (1) CN1255130A (da)
AR (1) AR012602A1 (da)
AT (1) ATE210661T1 (da)
AU (1) AU734394B2 (da)
BR (1) BR9808725A (da)
CA (1) CA2287999A1 (da)
DE (1) DE69802923T2 (da)
DK (1) DK0983266T3 (da)
EE (1) EE9900475A (da)
ES (1) ES2168757T3 (da)
HU (1) HUP0003766A3 (da)
ID (1) ID23156A (da)
IL (1) IL132677A0 (da)
IS (1) IS5237A (da)
MX (1) MXPA99009874A (da)
NO (1) NO995404L (da)
NZ (1) NZ500676A (da)
PL (1) PL336854A1 (da)
PT (1) PT983266E (da)
SE (1) SE9701682D0 (da)
SK (1) SK140699A3 (da)
TR (1) TR199902719T2 (da)
WO (1) WO1998050380A1 (da)
ZA (1) ZA983740B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1330901A (en) * 1999-10-06 2001-05-10 Brigham And Women's Hospital Compounds and methods for modulating non-transcriptional effects of steroid hormones
US6683108B1 (en) * 2000-03-30 2004-01-27 Curis, Inc. Agonists of hedgehog signaling pathways and uses related thereto
US7115653B2 (en) * 2000-03-30 2006-10-03 Curis, Inc. Small organic molecule regulators of cell proliferation
US8852937B2 (en) * 2000-03-30 2014-10-07 Curis, Inc. Small organic molecule regulators of cell proliferation
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
CN1642946A (zh) * 2002-03-22 2005-07-20 株式会社Lg生命科学 (2s)－n－{5－[氨基(亚氨基)甲基]－2－噻吩基}甲基－1－{(2r)－2－[(羧甲基)氨基]3，－二苯基丙酰}－2－吡咯烷甲酰胺的马来酸盐及其制备方法
ZA200709038B (en) 2005-04-13 2009-01-28 Neuraxon Inc Substituted indole compounds having nos inhibitory activity
TWI417099B (zh) * 2007-03-23 2013-12-01 Neuraxon Inc 具抑制一氧化氮合成酶活性之喹諾酮、四氫喹啉及其相關化合物
EA201000808A1 (ru) 2007-11-16 2011-04-29 Ньюраксон, Инк. Индольные соединения и способы лечения висцеральной боли

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504278A (ja) * 1944-06-01 1997-04-28 ザ、ウェルカム、ファンデーション、リミテッド Ｎｏシンターゼインヒビターとしての置換尿素およびイソチオ尿素誘導体
PL180081B1 (pl) * 1993-08-12 2000-12-29 Astra Ab Nowe pochodne amidyny i sposób ich wytwarzania PL PL PL PL PL PL PL
KR100342275B1 (ko) * 1993-10-21 2002-12-05 지.디. 썰 엘엘씨 산화질소신타제저해제로서유용한아미디노유도체
CA2188680A1 (en) * 1994-05-07 1996-01-25 James Edwin Macdonald Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
KR970706272A (ko) * 1995-08-10 1997-11-03 클래스 빌헬름슨 치료에 유용한 바이시클릭 아미딘 유도체(Bicyclic Amidine Derivatives Useful in Therapy)

Also Published As

Publication number Publication date
NO995404D0 (no) 1999-11-04
MXPA99009874A (es) 2004-09-30
IS5237A (is) 1999-11-01
ES2168757T3 (es) 2002-06-16
ID23156A (id) 2000-03-23
CN1255130A (zh) 2000-05-31
ATE210661T1 (de) 2001-12-15
HUP0003766A3 (en) 2001-09-28
NZ500676A (en) 2001-05-25
NO995404L (no) 2000-01-05
EE9900475A (et) 2000-06-15
AU7460098A (en) 1998-11-27
CA2287999A1 (en) 1998-11-12
TR199902719T2 (xx) 2000-02-21
DE69802923T2 (de) 2002-07-04
WO1998050380A1 (en) 1998-11-12
HUP0003766A2 (en) 2001-03-28
DE69802923D1 (de) 2002-01-24
JP2001523263A (ja) 2001-11-20
SK140699A3 (en) 2000-06-12
DK0983266T3 (da) 2002-03-11
US6166030A (en) 2000-12-26
EP0983266A1 (en) 2000-03-08
AR012602A1 (es) 2000-11-08
AU734394B2 (en) 2001-06-14
SE9701682D0 (sv) 1997-05-05
PT983266E (pt) 2002-05-31
KR20010012227A (ko) 2001-02-15
EP0983266B1 (en) 2001-12-12
BR9808725A (pt) 2000-07-11
PL336854A1 (en) 2000-07-17
IL132677A0 (en) 2001-03-19

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