ZA984466B - Process for obtaining quinapril hydrochloride and solvates useful for the isolation and purification of quinapril hydrochloride - Google Patents

Process for obtaining quinapril hydrochloride and solvates useful for the isolation and purification of quinapril hydrochloride

Info

Publication number
ZA984466B
ZA984466B ZA984466A ZA984466A ZA984466B ZA 984466 B ZA984466 B ZA 984466B ZA 984466 A ZA984466 A ZA 984466A ZA 984466 A ZA984466 A ZA 984466A ZA 984466 B ZA984466 B ZA 984466B
Authority
ZA
South Africa
Prior art keywords
quinapril hydrochloride
solvate
quinapril
obtaining
isolation
Prior art date
Application number
ZA984466A
Other languages
English (en)
Inventor
Montserrat Monsalva Liagostera
Marti Bartra Sanmarti
Jaime Tomas Navarro
Salvador Poug Torres
Original Assignee
Esteve Quimica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Quimica Sa filed Critical Esteve Quimica Sa
Publication of ZA984466B publication Critical patent/ZA984466B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
ZA984466A 1997-05-29 1998-05-26 Process for obtaining quinapril hydrochloride and solvates useful for the isolation and purification of quinapril hydrochloride ZA984466B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09701169A ES2122941B1 (es) 1997-05-29 1997-05-29 Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato.

Publications (1)

Publication Number Publication Date
ZA984466B true ZA984466B (en) 1998-12-01

Family

ID=8299498

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA984466A ZA984466B (en) 1997-05-29 1998-05-26 Process for obtaining quinapril hydrochloride and solvates useful for the isolation and purification of quinapril hydrochloride

Country Status (13)

Country Link
US (2) USRE39888E1 (de)
EP (1) EP0992495B1 (de)
JP (1) JP2002502386A (de)
KR (1) KR100477713B1 (de)
AT (1) ATE258920T1 (de)
AU (1) AU730140B2 (de)
CA (1) CA2293705C (de)
DE (1) DE69821483T2 (de)
DK (1) DK0992495T3 (de)
ES (1) ES2122941B1 (de)
PT (1) PT992495E (de)
WO (1) WO1998054149A1 (de)
ZA (1) ZA984466B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
AU2002361494A1 (en) * 2002-12-16 2004-07-09 Lupin Limited Crystalline form of quinapril hydrochloride and process for preparing the same
CL2004000541A1 (es) 2003-03-31 2005-02-04 Warner Lambert Co Procedimiento de preparacion de clorhidrato de quinapril por reaccion entre una 2,5-dioxo-oxazolidina y un ester terbutilico de una tetrahidro isoquinolina, util como principio activo para tratar la hipertension y la insuficiencia cardiaca congestiva
WO2007054966A2 (en) * 2005-09-13 2007-05-18 Aarti Healthcare Limited A process for the preparation of highly pure crystalline quinapril hydrochloride
WO2007069268A2 (en) * 2005-10-14 2007-06-21 Sun Pharmaceutical Industries Limited A process for the preparation of substantially pure 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives
WO2009053994A1 (en) * 2007-10-26 2009-04-30 Matrix Laboratories Limited Process for preparing pure amorphous quinapril hydrochloride

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
IN156096B (de) * 1981-03-19 1985-05-11 Usv Pharma Corp
JPS58188857A (ja) * 1982-04-26 1983-11-04 Takeda Chem Ind Ltd テトラヒドロイソキノリン誘導体
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3333454A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
US4761479A (en) * 1987-03-30 1988-08-02 Warner-Lambert Company Crystalline quinapril and a process for producing the same
JPH01275546A (ja) * 1988-04-26 1989-11-06 Nisso Yuka Kogyo Kk 安息香酸ソーダの単離方法
DE4206697A1 (de) * 1992-03-04 1993-09-09 Hoechst Ag Verfahren zur herstellung von modifizierten phenolharzen
JP3211396B2 (ja) * 1992-08-26 2001-09-25 住友化学工業株式会社 アクリル酸及び酢酸の回収方法

Also Published As

Publication number Publication date
ES2122941A1 (es) 1998-12-16
ES2122941B1 (es) 1999-07-01
AU7336598A (en) 1998-12-30
JP2002502386A (ja) 2002-01-22
ATE258920T1 (de) 2004-02-15
EP0992495B1 (de) 2004-02-04
US6617457B1 (en) 2003-09-09
EP0992495A1 (de) 2000-04-12
DE69821483T2 (de) 2005-01-13
KR20010013167A (ko) 2001-02-26
KR100477713B1 (ko) 2005-03-18
AU730140B2 (en) 2001-03-01
CA2293705C (en) 2008-03-18
WO1998054149A1 (es) 1998-12-03
DK0992495T3 (da) 2004-06-01
DE69821483D1 (de) 2004-03-11
CA2293705A1 (en) 1998-12-03
PT992495E (pt) 2004-06-30
USRE39888E1 (en) 2007-10-16

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