ZA986334B - Medicaments comprising a polyhydroxyalkylpyrazine derivative novel derivatives and their preparation - Google Patents

Medicaments comprising a polyhydroxyalkylpyrazine derivative novel derivatives and their preparation

Info

Publication number
ZA986334B
ZA986334B ZA986334A ZA986334A ZA986334B ZA 986334 B ZA986334 B ZA 986334B ZA 986334 A ZA986334 A ZA 986334A ZA 986334 A ZA986334 A ZA 986334A ZA 986334 B ZA986334 B ZA 986334B
Authority
ZA
South Africa
Prior art keywords
formula
ch2oh
choh
polyhydroxyalkylpyrazine
medicaments
Prior art date
Application number
ZA986334A
Other languages
English (en)
Inventor
Georges Bashiardes
Jean-Christophe Carry
Michel Evers
Bruno Filoche
Serge Mignani
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of ZA986334B publication Critical patent/ZA986334B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA986334A 1997-07-17 1998-07-16 Medicaments comprising a polyhydroxyalkylpyrazine derivative novel derivatives and their preparation ZA986334B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9709060A FR2766184B1 (fr) 1997-07-17 1997-07-17 Medicaments contenant en tant que principe actif au moins un derive de polyhydroxylalkylpyrazine, les nouveaux derives de polyhydroxylalkylpyrazine et leur preparation

Publications (1)

Publication Number Publication Date
ZA986334B true ZA986334B (en) 1999-02-02

Family

ID=9509303

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA986334A ZA986334B (en) 1997-07-17 1998-07-16 Medicaments comprising a polyhydroxyalkylpyrazine derivative novel derivatives and their preparation

Country Status (24)

Country Link
US (2) US6392042B1 (de)
EP (1) EP0998465B1 (de)
JP (1) JP4443034B2 (de)
KR (1) KR20010021822A (de)
CN (1) CN1264370A (de)
AT (1) ATE249442T1 (de)
AU (1) AU751090B2 (de)
BR (1) BR9811013A (de)
CA (1) CA2296739C (de)
CZ (1) CZ290908B6 (de)
DE (1) DE69818060T2 (de)
DK (1) DK0998465T3 (de)
ES (1) ES2206978T3 (de)
FR (1) FR2766184B1 (de)
HU (1) HUP0002821A3 (de)
IL (1) IL134038A0 (de)
MX (1) MXPA00000252A (de)
NO (1) NO20000055L (de)
NZ (1) NZ502276A (de)
PL (1) PL338133A1 (de)
RU (1) RU2192420C2 (de)
SK (1) SK472000A3 (de)
WO (1) WO1999003842A1 (de)
ZA (1) ZA986334B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1704862A1 (de) * 2005-03-24 2006-09-27 Rottapharm S.p.A. 2,5-bis(tetrahydroxybutyl)pyrazin-Derivaten zur Behandlung von Osteoarthritis und rheumatoider Arthritis
CN100371330C (zh) * 2006-01-24 2008-02-27 湖南中烟工业公司 从糖氨反应液中分离提纯多羟基烷基吡嗪类化合物的方法
CN105294579B (zh) * 2015-11-27 2018-07-20 中国科学院山西煤炭化学研究所 一种利用甲壳素类生物质制备脱氧果糖嗪的方法
US11091446B2 (en) * 2017-03-24 2021-08-17 R.J. Reynolds Tobacco Company Methods of selectively forming substituted pyrazines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL64267A (en) * 1980-12-09 1985-08-30 Erba Farmitalia Ethers of hydroxymethylpyrazin-n-oxides,their preparation and pharmaceutical compositions containing them
WO1995030660A1 (fr) * 1994-05-10 1995-11-16 Firmenich S.A. Procede pour la preparation de pyrazines substituees
DE19547543A1 (de) 1995-12-20 1997-06-26 Teves Gmbh Alfred Teilbelagscheibenbremse mit einem Schwimmsattel
FR2744365B1 (fr) * 1996-02-06 1998-02-27 Inst Malgache Rech Appl Melanges isolables a partir de graines d'eugenia jambolana lamarck, leur preparation et l'utilisation de ces melanges et certains de leurs constituants comme medicaments

Also Published As

Publication number Publication date
ES2206978T3 (es) 2004-05-16
US6392042B1 (en) 2002-05-21
DK0998465T3 (da) 2003-12-15
HUP0002821A3 (en) 2001-07-30
JP4443034B2 (ja) 2010-03-31
JP2001510186A (ja) 2001-07-31
AU8810498A (en) 1999-02-10
US20040209890A1 (en) 2004-10-21
RU2192420C2 (ru) 2002-11-10
CZ2000122A3 (cs) 2000-05-17
CN1264370A (zh) 2000-08-23
CZ290908B6 (cs) 2002-11-13
EP0998465B1 (de) 2003-09-10
PL338133A1 (en) 2000-09-25
WO1999003842A1 (fr) 1999-01-28
MXPA00000252A (es) 2002-04-24
IL134038A0 (en) 2001-04-30
HUP0002821A2 (hu) 2001-05-28
FR2766184A1 (fr) 1999-01-22
AU751090B2 (en) 2002-08-08
NO20000055D0 (no) 2000-01-06
CA2296739C (fr) 2008-09-23
SK472000A3 (en) 2000-06-12
ATE249442T1 (de) 2003-09-15
EP0998465A1 (de) 2000-05-10
DE69818060D1 (de) 2003-10-16
NO20000055L (no) 2000-01-06
NZ502276A (en) 2001-09-28
FR2766184B1 (fr) 2000-11-17
KR20010021822A (ko) 2001-03-15
DE69818060T2 (de) 2004-07-08
BR9811013A (pt) 2000-08-15
CA2296739A1 (fr) 1999-01-28

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