ZA986874B - Alatrofloxacin parenteral compositions. - Google Patents

Alatrofloxacin parenteral compositions.

Info

Publication number: ZA986874B
Authority: ZA; South Africa
Prior art keywords: alatrofloxacin; parenteral compositions; parenteral; compositions; alatrofloxacin parenteral
Prior art date: 1997-08-01

Application number

ZA9806874A

Other languages

English (en)

Inventor

Robert Mark Guinn

John Francis Lambert

Subramanian Sam Guhan

Stanley Walter Walinsky

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-01

Filing date

1998-07-31

Publication date

2000-01-31

1998-07-31 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2000-01-31 Publication of ZA986874B publication Critical patent/ZA986874B/xx

Links

UUZPPAMZDFLUHD-VUJLHGSVSA-N alatrofloxacin Chemical compound C([C@@H]1[C@H]([C@@H]1C1)NC(=O)[C@H](C)NC(=O)[C@@H](N)C)N1C(C(=CC=1C(=O)C(C(O)=O)=C2)F)=NC=1N2C1=CC=C(F)C=C1F UUZPPAMZDFLUHD-VUJLHGSVSA-N 0.000 title 1
229960000919 alatrofloxacin Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

ZA9806874A 1997-08-01 1998-07-31 Alatrofloxacin parenteral compositions. ZA986874B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5424697P	1997-08-01	1997-08-01

Publications (1)

Publication Number	Publication Date
ZA986874B true ZA986874B (en)	2000-01-31

Family

ID=21989735

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9806874A ZA986874B (en)	1997-08-01	1998-07-31	Alatrofloxacin parenteral compositions.

Country Status (40)

Country	Link
US (1)	US6194429B1 (fr)
EP (1)	EP1000086B1 (fr)
JP (1)	JP3463928B2 (fr)
KR (1)	KR20010022495A (fr)
CN (1)	CN1265671A (fr)
AP (1)	AP1031A (fr)
AR (1)	AR015417A1 (fr)
AT (1)	ATE259827T1 (fr)
AU (1)	AU734863B2 (fr)
BG (1)	BG104105A (fr)
BR (1)	BR9811580A (fr)
CA (1)	CA2296466C (fr)
CO (1)	CO4970688A1 (fr)
DE (1)	DE69821767T2 (fr)
DK (1)	DK1000086T3 (fr)
DZ (1)	DZ2576A1 (fr)
EA (1)	EA002120B1 (fr)
ES (1)	ES2214716T3 (fr)
GT (1)	GT199800112A (fr)
HN (1)	HN1998000106A (fr)
HR (1)	HRP980417B1 (fr)
HU (1)	HUP0004793A3 (fr)
ID (1)	ID24374A (fr)
IL (1)	IL134156A0 (fr)
IS (1)	IS5339A (fr)
MA (1)	MA24626A1 (fr)
NO (1)	NO20000485L (fr)
NZ (1)	NZ502249A (fr)
OA (1)	OA11281A (fr)
PA (1)	PA8456701A1 (fr)
PE (1)	PE103799A1 (fr)
PL (1)	PL338477A1 (fr)
PT (1)	PT1000086E (fr)
SK (1)	SK1012000A3 (fr)
TN (1)	TNSN98146A1 (fr)
TW (1)	TW538043B (fr)
UY (1)	UY25113A1 (fr)
WO (1)	WO1999006430A1 (fr)
YU (1)	YU2500A (fr)
ZA (1)	ZA986874B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE285821T1 (de) *	1999-10-08	2005-01-15	Affinium Pharm Inc	Fab i inhibitoren
EP1121933A1 (fr) *	2000-02-02	2001-08-08	Pfizer Products Inc.	Compositions prémélangées injectables d'alatrofloxacin
CA2444597A1 (fr)	2001-04-06	2002-10-06	Affinium Pharmaceuticals, Inc.	Inhibiteurs de fab i
EP1575951B1 (fr)	2002-12-06	2014-06-25	Debiopharm International SA	Composes heterocycliques, procedes de production de ceux-ci et utilisation de ceux-ci dans un traitement
DE602004016831D1 (de)	2003-03-17	2008-11-13	Affinium Pharm Inc	Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
CA2467321A1 (fr) *	2004-05-14	2005-11-14	Paul J. Santerre	Agents de couplage polymeres et polymeres ayant une activite pharmaceutique produits a partir de ceux-ci
EP2848614A3 (fr)	2004-06-04	2015-07-29	Debiopharm International SA	Dérivés de acrylamide et leur utilisation comme agents antibiotiques
EP1973902A2 (fr) *	2005-12-05	2008-10-01	Affinium Pharmaceuticals, Inc.	Agents therapeutiques et ses procédés de fabrication et d utilisation
EP2687533B1 (fr)	2006-07-20	2017-07-19	Debiopharm International SA	Dérivés d'acrylamide en tant qu'inhibiteurs de FAB I
WO2008098374A1 (fr)	2007-02-16	2008-08-21	Affinium Pharmaceuticals, Inc.	Sels, promédicaments et polymorphes d'inhibiteurs de fab 1
SI2861608T1 (sl)	2012-06-19	2019-08-30	Debiopharm International Sa	Derivati predzdravila (E)-N-metil-N-((3-metilbenzofuran-2-IL)metil)- 3-(7-okso-5,6,7,8-tetrahidro-1 ,8-nafthiridin-3-il)akrilamid
EP3134103B1 (fr) *	2014-04-25	2020-01-15	Naurex Inc.	Compositions stables de peptides neuroactifs
BR122023021456A2 (pt)	2016-02-26	2024-02-20	Debiopharm International S.A.	Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica
CN111971292B (zh)	2018-02-02	2024-12-13	波纹疗法公司	包含类固醇二聚体的玻璃制剂及其用途
WO2020154815A1 (fr)	2019-02-01	2020-08-06	Ripple Therapeutics Corporation	Formes cristallines de dimères de dexaméthasone et leurs utilisations
LT3923914T (lt)	2019-02-14	2023-07-25	Debiopharm International S.A.	Afabicino kompozicija, jos gamybos būdas
CN113939306B (zh)	2019-06-14	2024-07-19	德彪药业国际股份公司	用于治疗涉及生物膜的细菌感染的药物及其用途
WO2021024041A1 (fr)	2019-08-07	2021-02-11	Ripple Therapeutics Corporation	Dimères de médicaments à libération contrôlée
MX2022013665A (es)	2020-05-01	2022-11-30	Ripple Therapeutics Corp	Composiciones y metodos heterodimeros para el tratamiento de trastornos oculares.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3713672A1 (de)	1987-04-24	1988-11-17	Bayer Ag	Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren
US5164402A (en)	1989-08-16	1992-11-17	Pfizer Inc	Azabicyclo quinolone and naphthyridinone carboxylic acids
US5256791A (en)	1992-03-02	1993-10-26	Pfizer Inc.	Preparation of intermediates in the synthesis of quinoline antibiotics
CZ286896B6 (en)	1994-01-18	2000-07-12	Pfizer	Process for preparing pharmaceutically acceptable salts of naphthyridone carboxylic acid and intermediates for this preparation
TW420610B (en)	1994-04-07	2001-02-01	Pfizer	A pharmaceutical composition for treating a H. pylori infection or gastric or duodenal ulcers
US5475116A (en)	1994-04-29	1995-12-12	Pfizer Inc.	Aza bicyclo[3,1,0]hexane intermediates useful in the synthesis of quinolones
US5763454A (en)	1995-06-06	1998-06-09	Pfizer, Inc.	Crystal form of anhydrous 7-( 1α,5α,6α!-6-amino-3-azabicyclo 3.1.0!hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8 naphthyridine-3-carboxylic acid, methanessulfonic acid salt
ATE221544T1 (de) *	1995-06-15	2002-08-15	Pfizer	Verfahren zur herstellung von derivaten der ein peptid enthaltenden azabizylo-naphtyridin- carbonsäure
SK23898A3 (en)	1995-08-29	1999-05-07	Pfizer	Zwitterionic forms of trovafloxacin
DE69617027T2 (de) *	1995-08-29	2002-03-21	Pfizer Inc., New York	Polymorphs von prodrug 6-n(l-ala-l-ala)-trovafloxacin
GB9524466D0 (en)	1995-11-30	1996-01-31	Pfizer Ltd	Process
JPH1087617A (ja)	1996-07-09	1998-04-07	Pfizer Inc	キノリン系抗生物質の合成に有用な中間体の製法

1998
- 1998-07-10 HN HN1998000106A patent/HN1998000106A/es unknown
- 1998-07-23 CA CA002296466A patent/CA2296466C/fr not_active Expired - Fee Related
- 1998-07-23 ES ES98932444T patent/ES2214716T3/es not_active Expired - Lifetime
- 1998-07-23 US US09/403,886 patent/US6194429B1/en not_active Expired - Fee Related
- 1998-07-23 EA EA200000086A patent/EA002120B1/ru not_active IP Right Cessation
- 1998-07-23 PT PT98932444T patent/PT1000086E/pt unknown
- 1998-07-23 WO PCT/IB1998/001122 patent/WO1999006430A1/fr not_active Ceased
- 1998-07-23 YU YU2500A patent/YU2500A/sh unknown
- 1998-07-23 HU HU0004793A patent/HUP0004793A3/hu unknown
- 1998-07-23 ID IDW20000200A patent/ID24374A/id unknown
- 1998-07-23 AU AU82368/98A patent/AU734863B2/en not_active Ceased
- 1998-07-23 CN CN98807829A patent/CN1265671A/zh active Pending
- 1998-07-23 IL IL13415698A patent/IL134156A0/xx unknown
- 1998-07-23 PL PL98338477A patent/PL338477A1/xx not_active Application Discontinuation
- 1998-07-23 EP EP98932444A patent/EP1000086B1/fr not_active Expired - Lifetime
- 1998-07-23 JP JP2000505185A patent/JP3463928B2/ja not_active Expired - Fee Related
- 1998-07-23 SK SK101-2000A patent/SK1012000A3/sk unknown
- 1998-07-23 KR KR1020007001081A patent/KR20010022495A/ko not_active Ceased
- 1998-07-23 NZ NZ502249A patent/NZ502249A/en unknown
- 1998-07-23 AT AT98932444T patent/ATE259827T1/de not_active IP Right Cessation
- 1998-07-23 BR BR9811580-4A patent/BR9811580A/pt not_active Application Discontinuation
- 1998-07-23 DE DE1998621767 patent/DE69821767T2/de not_active Expired - Fee Related
- 1998-07-23 DK DK98932444T patent/DK1000086T3/da active
- 1998-07-24 GT GT199800112A patent/GT199800112A/es unknown
- 1998-07-24 PE PE1998000667A patent/PE103799A1/es not_active Application Discontinuation
- 1998-07-27 TW TW087112260A patent/TW538043B/zh not_active IP Right Cessation
- 1998-07-28 HR HR980417A patent/HRP980417B1/xx not_active IP Right Cessation
- 1998-07-28 UY UY25113A patent/UY25113A1/es unknown
- 1998-07-29 DZ DZ980186A patent/DZ2576A1/fr active
- 1998-07-30 AP APAP/P/1998/001310A patent/AP1031A/en active
- 1998-07-31 CO CO98043890A patent/CO4970688A1/es unknown
- 1998-07-31 AR ARP980103814A patent/AR015417A1/es unknown
- 1998-07-31 ZA ZA9806874A patent/ZA986874B/xx unknown
- 1998-07-31 MA MA25198A patent/MA24626A1/fr unknown
- 1998-07-31 TN TNTNSN98146A patent/TNSN98146A1/fr unknown
- 1998-08-03 PA PA19988456701A patent/PA8456701A1/es unknown
2000
- 2000-01-14 IS IS5339A patent/IS5339A/is unknown
- 2000-01-25 BG BG104105A patent/BG104105A/bg unknown
- 2000-01-26 OA OA1200000019A patent/OA11281A/en unknown
- 2000-01-31 NO NO20000485A patent/NO20000485L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HRP980417A2 (en)	1999-08-31
JP3463928B2 (ja)	2003-11-05
TNSN98146A1 (fr)	2005-03-15
BG104105A (bg)	2000-08-31
EA200000086A1 (ru)	2000-08-28
JP2001512133A (ja)	2001-08-21
HUP0004793A3 (en)	2001-10-29
DK1000086T3 (da)	2004-05-17
BR9811580A (pt)	2000-08-22
NO20000485D0 (no)	2000-01-31
NO20000485L (no)	2000-03-27
IS5339A (is)	2000-01-14
GT199800112A (es)	2000-01-15
EP1000086A1 (fr)	2000-05-17
EA002120B1 (ru)	2001-12-24
AU8236898A (en)	1999-02-22
CO4970688A1 (es)	2000-11-07
YU2500A (sh)	2002-09-19
HUP0004793A2 (hu)	2001-04-28
AR015417A1 (es)	2001-05-02
US6194429B1 (en)	2001-02-27
ATE259827T1 (de)	2004-03-15
DZ2576A1 (fr)	2003-02-22
NZ502249A (en)	2001-11-30
ID24374A (id)	2000-07-13
DE69821767T2 (de)	2005-01-13
KR20010022495A (ko)	2001-03-15
IL134156A0 (en)	2001-04-30
AP1031A (en)	2001-12-21
OA11281A (en)	2002-11-19
DE69821767D1 (de)	2004-03-25
AU734863B2 (en)	2001-06-21
PL338477A1 (en)	2000-11-06
CA2296466A1 (fr)	1999-02-11
TW538043B (en)	2003-06-21
SK1012000A3 (en)	2000-09-12
EP1000086B1 (fr)	2004-02-18
CN1265671A (zh)	2000-09-06
WO1999006430A1 (fr)	1999-02-11
PA8456701A1 (es)	2000-05-24
CA2296466C (fr)	2003-04-15
HRP980417B1 (en)	2002-10-31
AP9801310A0 (en)	1998-09-30
ES2214716T3 (es)	2004-09-16
HN1998000106A (es)	1999-01-08
PT1000086E (pt)	2004-05-31
MA24626A1 (fr)	1999-04-01
PE103799A1 (es)	1999-10-25
UY25113A1 (es)	2000-12-29

Publication	Publication Date	Title
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